The DOI matches its Crossref record; 35 of the 35 references it cites were found in a registry or an index.
Circulating (cell‐free) nucleic acids – A promising, non‐invasive tool for early detection of several human diseases
Abstract
Circulating nucleic acids (CNA) are present in small amounts in the plasma of healthy individuals. However, increased levels of plasma CNA have been reported in a number of clinical disorders like cancer, stroke, trauma, myocardial infarction, autoimmune disorders, and pregnancy‐associated complications. CNA has received special attention because of its potential application as a non‐invasive, rapid and sensitive tool for molecular diagnosis and monitoring of acute pathologies and the prenatal diagnosis of fetal genetic diseases. This review throws light on the current status of blood CNA as a diagnostic marker and its potential as a powerful tool in the future.
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Citations
Cites
1 retracted
p53 mutation in plasma DNA and its prognostic value in breast cancer patients.
Shao, Z. M., Wu, J., Shen, Z., & Nguyen, M. (2001) · PubMed · Cited by 64
RetractedA simple, rapid, and sensitive DNA assay procedure
Labarca, C., & Paigen, K. (1980) · Analytical Biochemistry · doi:10.1016/0003-2697(80)90165-7 · Cited by 4,901
Presence of fetal DNA in maternal plasma and serum
Lo, Y. M. D., Corbetta, N., Chamberlain, P. F., Rai, V., Sargent, I. L., Redman, C. W., & Wainscoat, J. S. (1997) · The Lancet · doi:10.1016/s0140-6736(97)02174-0 · Cited by 3,129
(1977) · PubMed · Cited by 1,801
Nuclear Acids In Human Blood Plasma.
Mandel, P., & Métais, P. (1948) · PubMed · Cited by 1,196
Tan, E. M., Schur, P. H., Carr, R. I., & Kunkel, H. G. (1966) · Journal of Clinical Investigation · doi:10.1172/jci105479 · Cited by 845
(15031584), Y. M. D. L., Chan, L. Y. S., Lo, K. W., Leung, S. F., Zhang, J., Chan, A. T. �., Lee, J. C., Hjelm, N. M., Johnson, P. J., & Huang, D. P. (1999) · PubMed · Cited by 777
Microsatellite alterations in serum DNA of head and neck cancer patients
Nawroz, H., Koch, W., Anker, P., Stroun, M., & Sidransky, D. (1996) · Nature Medicine · doi:10.1038/nm0996-1035 · Cited by 658
Microsatellite alterations in plasma DNA of small cell lung cancer patients
Qi Chen, X., Stroun, M., Magnenat, J.-L., Nicod, L. P., Kurt, A.-M., Lyautey, J., Lederrey, C., & Anker, P. (1996) · Nature Medicine · doi:10.1038/nm0996-1033 · Cited by 647
Soluble normal and mutated DNA sequences from single-copy genes in human blood.
Sorenson, G. D., Pribish, D. M., Valone, F. H., Memoli, V. A., Bzik, D. J., & Yao, S. (1994) · PubMed · Cited by 530
Cited by
Integrating liquid biopsies into the management of cancer
Siravegna, G., Marsoni, S., Siena, S., & Bardelli, A. (2017) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2017.14 · Cited by 1,908
Origins, structures, and functions of circulating DNA in oncology
Thierry, A. R., El Messaoudi, S., Gahan, P. B., Anker, P., & Stroun, M. (2016) · Cancer and Metastasis Reviews · doi:10.1007/s10555-016-9629-x · Cited by 818
Circulating Exosomal microRNAs as Biomarkers of Colon Cancer
Ogata-Kawata, H., Izumiya, M., Kurioka, D., Honma, Y., Yamada, Y., Furuta, K., Gunji, T., Ohta, H., Okamoto, H., Sonoda, H., et al. (2014) · PLoS ONE · doi:10.1371/journal.pone.0092921 · Cited by 809
Circulating cell free DNA: Preanalytical considerations
El Messaoudi, S., Rolet, F., Mouliere, F., & Thierry, A. R. (2013) · Clinica Chimica Acta · doi:10.1016/j.cca.2013.05.022 · Cited by 560
Pant, S., Hilton, H., & Burczynski, M. E. (2012) · Biochemical Pharmacology · doi:10.1016/j.bcp.2011.12.037 · Cited by 473
Metadata
- Authors
- Swarup, V., & Rajeswari, M. R.
- Venue
- FEBS Letters
- Publisher
- Wiley
- Published
- 2007-02-02
- Volume
- 581
- Issue
- 5
- Pages
- 795-799
- ISSN
- 0014-5793 (ISSN-L)
- 1873-3468
- OpenAlex
- W2164320986
- Cited by
- 379
- References
- 35
- FWCI
- 5.14
- Type
- journal article
- Language
- en
- Open access
- closed
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- Swarup, V., & Rajeswari, M. R. (2007). Circulating (cell‐free) nucleic acids – A promising, non‐invasive tool for early detection of several human diseases. FEBS Letters. https://doi.org/10.1016/j.febslet.2007.01.051
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.