The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy
Abstract
Purine salvage is an essential function for all obligate parasitic protozoa studied to date and most are also capable of efficient uptake of preformed pyrimidines. Much progress has been made in the identification and characterisation of protozoan purine and pyrimidine transporters. While the genes encoding protozoan or metazoan pyrimidine transporters have yet to be identified, numerous purine transporters have now been cloned. All protozoan purine transporter-encoding genes characterised to date have been of the Equilibrative Nucleoside Transporter family conserved in a great variety of eukaryote organisms. However, these protozoan transporters have been shown to be sufficiently different from mammalian transporters to mediate selective uptake of therapeutic agents. Recent studies are increasingly addressing the structure and substrate recognition mechanisms of these vital transport proteins.
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Quartet Puzzling: A Quartet Maximum-Likelihood Method for Reconstructing Tree Topologies
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Morgenstern, B. (1999) · Bioinformatics · doi:10.1093/bioinformatics/15.3.211 · Cited by 678
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Drugs and drug resistance in African trypanosomiasis
DELESPAUX, V, & DEKONING, H. (2007) · Drug Resistance Updates · doi:10.1016/j.drup.2007.02.004 · Cited by 288
Self-citationNucleoside transporters: from scavengers to novel therapeutic targets
King, A. E., Ackley, M. A., Cass, C. E., Young, J. D., & Baldwin, S. A. (2006) · Trends in Pharmacological Sciences · doi:10.1016/j.tips.2006.06.004 · Cited by 278
A novel route for ATP acquisition by the remnant mitochondria of Encephalitozoon cuniculi
Tsaousis, A. D., Kunji, E. R. S., Goldberg, A. V., Lucocq, J. M., Hirt, R. P., & Embley, T. M. (2008) · Nature · doi:10.1038/nature06903 · Cited by 268
Metadata
- Authors
- de Koning, H. P., Bridges, D. J., & Burchmore, R. J. S.
- Venue
- FEMS Microbiology Reviews
- Publisher
- Oxford University Press (OUP)
- Published
- 2005-11
- Volume
- 29
- Issue
- 5
- Pages
- 987-1020
- ISSN
- 0168-6445 (ISSN-L)
- 1574-6976
- OpenAlex
- W2081190990
- Cited by
- 196
- References
- 3
- FWCI
- 4.72
- Type
- journal article
- Language
- en
- Open access
- closed
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- de Koning, H. P., Bridges, D. J., & Burchmore, R. J. S. (2005). Purine and pyrimidine transport in pathogenic protozoa: From biology to therapy. FEMS Microbiology Reviews. https://doi.org/10.1016/j.femsre.2005.03.004
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
