Cited by 589Ovarian function and disordersDiabetes, Cardiovascular Risks, and LipoproteinsGenetic and Kidney Cyst Diseases

The DOI matches its Crossref record; 57 of the 62 references it cites were found in a registry or an index.

Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment

Open access

DeUgarte, Catherine Marin, Bartolucci, Alfred A., Azziz, Ricardo·2005·Fertility and Sterility

DOI 10.1016/j.fertnstert.2004.11.070

Open this paper in CoChat — free account

Abstract

Objective To determine the prevalence of insulin resistance (IR) in a large population of patients with the polycystic ovary syndrome (PCOS).Design Prospective, case-control.Setting University medical center.Patient(s) Two hundred seventy-one PCOS patients and 260 eumenorrheic, non-hirsute, control women.Intervention(s) History and physical examination and blood sampling.Main outcome measure(s) Total T, free T, DHEAS, sex hormone-binding globulin, and fasting glucose and insulin levels; homeostatic model assessment values for IR (HOMA-IR) and percent beta-cell function (HOMA-%beta-cell).Result(s) Patients with PCOS and controls differed significantly in all parameters studied, except fasting glucose. Because the HOMA-IR and HOMA-%beta-cell values were variably associated with race, age, and body mass index, the HOMA-IR and HOMA-%beta-cell values were then adjusted for these cofounders. After adjustment, 64.4% of PCOS patients were noted to be insulin resistant, and 2.6% had beta-cell dysfunction. Compared with PCOS patients without IR (n = 96), patients with IR (n = 174) were more obese and had higher beta-cell function.Conclusion(s) In patients with PCOS, the prevalence of IR was 64% according to the HOMA-IR measurement, after adjustment. Patients with IR were more clinically affected. Although IR is a common abnormality in PCOS, it does not seem to be a universal feature.

Integrity signals

Registry

Crossref · 10.1016/j.fertnstert.2004.11.070

Cites

57 of 57 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Homeostasis model assessment: insulin resistance and ?-cell function from fasting plasma glucose and insulin concentrations in man
Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., & Turner, R. C. (1985) · Diabetologia · doi:10.1007/bf00280883 · Cited by 31,502
Use and Abuse of HOMA Modeling
Wallace, T. M., Levy, J. C., & Matthews, D. R. (2004) · Diabetes Care · doi:10.2337/diacare.27.6.1487 · Cited by 5,114
Quantitative Insulin Sensitivity Check Index: A Simple, Accurate Method for Assessing Insulin Sensitivity In Humans
Katz, A., Nambi, S. S., Mather, K., Baron, A. D., Follmann, D. A., Sullivan, G., & Quon, M. J. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6661 · Cited by 3,931
The Prevalence and Features of the Polycystic Ovary Syndrome in an Unselected Population
Azziz, R., Woods, K. S., Reyna, R., Key, T. J., Knochenhauer, E. S., & Yıldız, B. O. (2004) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2003-032046 · Cited by 2,715
Self-citation
Homeostasis model assessment closely mirrors the glucose clamp technique in the assessment of insulin sensitivity: Studies in subjects with various degrees of glucose tolerance and insulin sensitivity
Bonora, E., Targher, G., Alberiche, M., Bonadonna, R. C., Saggiani, F., Zenere, M. B., Monauni, T., & Muggeo, M. (2000) · Diabetes Care · doi:10.2337/diacare.23.1.57 · Cited by 2,456
Correct Homeostasis Model Assessment (HOMA) Evaluation Uses the Computer Program
Lévy, J., Matthews, D. R., & Hermans, M. P. (1998) · Diabetes Care · doi:10.2337/diacare.21.12.2191 · Cited by 2,023
Profound Peripheral Insulin Resistance, Independent of Obesity, in Polycystic Ovary Syndrome
Dunaif, A., Segal, K. R., Futterweit, W., & Dobrjansky, A. (1989) · Diabetes · doi:10.2337/diab.38.9.1165 · Cited by 1,967
Prevalence of the Polycystic Ovary Syndrome in Unselected Black and White Women of the Southeastern United States: A Prospective Study
Knochenhauer, E. S., Key, T. J., Kahsar-Miller, M., Waggoner, W., Boots, L. R., & Azziz, R. (1998) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.83.9.5090 · Cited by 1,759
Self-citation
Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
Legro, R. S. (1999) · Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.84.1.165 · Cited by 1,743
A Prospective Study of the Prevalence of the Polycystic Ovary Syndrome in Unselected Caucasian Women from Spain1
Asunción, M., Calvo, R. M., Millán, J. L. S., Sancho, J., Ávila, S., & Escobar-Morreale, H. F. (2000) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jcem.85.7.6682 · Cited by 1,328

Flagged first, then by citations

Show all 62 references

5 of the 62 references couldn’t be matched to a known paper.

Sorted by citations

Items 301–400 of 586

In an Ovine Model of Polycystic Ovary Syndrome (PCOS) Prenatal Androgens Suppress Female Fetal Renal Gluconeogenesis
Connolly, F., Rae, M. T., Späth, K., Boswell, L., McNeilly, A. S., & Duncan, W. C. (2015) · PLoS ONE · doi:10.1371/journal.pone.0132113 · Cited by 15
Harnessing Microbiome, Bacterial Extracellular Vesicle, and Artificial Intelligence for Polycystic Ovary Syndrome Diagnosis and Management
Kushawaha, B., Rem, T. T., & Pelosi, E. (2025) · Biomolecules · doi:10.3390/biom15060834 · Cited by 15
Association of increased levels of omentin‐1 and carotid intima‐media thickness with early signs of cardiovascular risk in patients with polycystic ovary syndrome: A prospective case control study
Tosun, Ş. A., GÜRBÜZ, T., Çebi, A., Tosun, A., Gökmen, O., & Usta, M. (2021) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.15077 · Cited by 17
Women With Polycystic Ovary Syndrome Have Comparable Hip Bone Geometry to Age-Matched Control Women
McBreairty, L. E., Zello, G. A., Gordon, J. J., Serrao, S. B., Pierson, R. A., Chizen, D. R., & Chilibeck, P. D. (2016) · Journal of Clinical Densitometry · doi:10.1016/j.jocd.2016.10.007 · Cited by 14
Alterations in plasma non-esterified fatty acid (NEFA) kinetics and relationship with insulin resistance in polycystic ovary syndrome
Ezeh, U. I., Arzumanyan, Z., Lizneva, D., Mathur, R., Chen, Y., Boston, R. C., Chen, Y. I., & Azziz, R. (2018) · Human Reproduction · doi:10.1093/humrep/dey356 · Cited by 14
Self-citation
Biomediators in Polycystic Ovary Syndrome and Cardiovascular Risk
Pandurevic, S., Μacut, D., Fanelli, F., Pagotto, U., & Gambineri, A. (2021) · Biomolecules · doi:10.3390/biom11091350 · Cited by 14
THYROID PROFILE IN POLYCYSTIC OVARIAN SYNDROME
Nanda, S. S., Dash, S., Behera, A., & Mishra, B. (2014) · Journal of Evolution of Medical and Dental Sciences · doi:10.14260/jemds/2014/3242 · Cited by 14
Insights into Manipulating Postprandial Energy Expenditure to Manage Weight Gain in Polycystic Ovary Syndrome
Siemienowicz, K. J., Rae, M. T., Howells, F., Anderson, C., Nicol, L. M., Franks, S., & Duncan, W. C. (2020) · iScience · doi:10.1016/j.isci.2020.101164 · Cited by 16
Effect of insulin and testosterone on androgen production and transcription of SULT2A1 in the NCI-h295r adrenocortical cell line
Kumar, A., Magoffin, D. A., Munir, I., & Azziz, R. (2008) · Fertility and Sterility · doi:10.1016/j.fertnstert.2008.05.076 · Cited by 14
Self-citation
Polycystic Ovary Syndrome and the Neuroendocrine Consequences of Androgen Excess
Silva, M. S. B., & Campbell, R. E. (2022) · Comprehensive physiology · doi:10.1002/cphy.c210025 · Cited by 22
The role of polycystic ovary syndrome in preclinical left ventricular diastolic dysfunction: an echocardiographic approach: a systematic review and meta-analysis
Mirzohreh, S., Panahi, P., Zafardoust, H., Zavvar, M., Fathi, N., Dehghan, M., & Sarbakhsh, P. (2023) · Cardiovascular Endocrinology & Metabolism · doi:10.1097/xce.0000000000000294 · Cited by 13
Effects of polyphenol in women with polycystic ovary syndrome: A systematic review and meta-analysis of randomized controlled trials
Balieiro, C. C. A., Hespanhol, L. C., Fonseca, L. M., Wantowski, S., Freitas, M. A. A., Dias, Y. J. M., Burlá, M. M., & de Oliveira, L. M. L. (2023) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2023.12.038 · Cited by 13
Adolescent PCOS and long-term metabolic risk: insights from triglycerides to high-density lipoprotein cholesterol ratio and high-density lipoprotein cholesterol profiles
Nowak-Ciołek, M., Stachowiak, J. J., Krok, K., Sokal, J., Malczyk, Ż., Skrzyńska, K., & Zachurzok, A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1579217 · Cited by 13
Evidence-Based Lifestyle and Pharmacological Management of Infertility in Women with Polycystic Ovary Syndrome
Costello, M., & Ledger, W. J. (2012) · Women s Health · doi:10.2217/whe.12.14 · Cited by 14
Polycystic ovary syndrome and metabolic syndrome: the worrisome twosome?
Shah, D., & Rasool, S. (2015) · Climacteric · doi:10.3109/13697137.2015.1116505 · Cited by 13
Anogenital distance and anti-Müllerian hormone combined improves the diagnosis of polycystic ovary syndrome
Prieto‐Sánchez, M. T., Peñalver, A. I. H., Sánchez-Ferrer, M. L., Mendiola, J., & Torres-Cantero, A. M. (2020) · Human Fertility · doi:10.1080/14647273.2020.1795574 · Cited by 13
Pioglitazone counteracts the tumor necrosis factor-α inhibition of follicle-stimulating hormone-induced follicular development and estradiol production in an in vitro mouse preantral follicle culture system
Hara, S., Takahashi, T., Amita, M., Matsuo, K., Igarashi, H., & Kurachi, H. (2013) · Journal of Ovarian Research · doi:10.1186/1757-2215-6-69 · Cited by 13
PHYSIOLOGY AND ENDOCRINOLOGY SYMPOSIUM: Insulin action and lipotoxicity in the development of polycystic ovary syndrome: A review1
Faubert, J., Battista, M., & Baillargeon, J. (2016) · Journal of Animal Science · doi:10.2527/jas.2015-0089 · Cited by 12
Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) in the Diagnosis of Insulin Resistance and Prediabetes
Bhosle, D. (2016) · Journal of Medical Science And clinical Research · doi:10.18535/jmscr/v4i9.65 · Cited by 13
Elevated CD14++CD16+ Monocytes in Hyperhomocysteinemia-Associated Insulin Resistance in Polycystic Ovary Syndrome
Zhang, B., Qi, X., Zhao, Y., Li, R., Zhang, C., Chang, H., Pang, Y., & Qiao, J. (2018) · Reproductive Sciences · doi:10.1177/1933719118756772 · Cited by 13
Comparative Study of Insulin Sensitivity and Resistance and Their Correlation with Androgens in Lean and Obese Women with Polycystic Ovary Syndrome
Misra, S., Gada, J. V., Dhole, C., Varthakavi, P. K., & Bhagwat, N. M. (2023) · Reproductive Sciences · doi:10.1007/s43032-023-01374-x · Cited by 12
Effect of circulating ceramides on adiposity and insulin resistance in patients with type 2 diabetes: An observational cross‐sectional study
Ofori, E. K., Buabeng, A., Amanquah, S. D., Danquah, K. O., Amponsah, S. K., Wormenor, D., Dogodzi, F. K., Adusu‐Donkor, L. X., Bernard, S. K., & Asare‐Anane, H. (2023) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.418 · Cited by 12
The role of metformin in ovulation induction: Current status
Elnashar, A. M. (2011) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2010.10.003 · Cited by 13
Serum brain natriuretic peptide and C-reactive protein levels in adolescent with polycystic ovary syndrome
Deveer, R., Üstün, Y. E., Uysal, S., Su, F. A., Sarıaslan, S., Gülerman, C., & Mollamahmutoğlu, L. (2012) · Gynecological Endocrinology · doi:10.3109/09513590.2011.650758 · Cited by 12
Plasma total oxidant and antioxidant status after oral glucose tolerance and mixed meal tests in patients with polycystic ovary syndrome
Küçükaydın, Z., Duran, C., Başaran, M., Camlica, F., Erdem, S. S., Basaran, A., Kutlu, O., BURNİK, F. S., Elmas, H., & Gönen, M. S. (2016) · Journal of Endocrinological Investigation · doi:10.1007/s40618-016-0498-5 · Cited by 12
Application of proteomics to the study of polycystic ovary syndrome.
Insenser, M. R., & Escobar-Morreale, H. F. (2011) · PubMed · doi:10.3275/8108 · Cited by 12
Oral and Vaginal Hormonal Contraceptives Induce Similar Unfavorable Metabolic Effects in Women with PCOS: A Randomized Controlled Trial
Mosorin, M., Piltonen, T., Rantala, A. S., Kangasniemi, M. H., Korhonen, E., Bloigu, R., Tapanainen, J. S., & Morin-Papunen, L. C. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12082827 · Cited by 11
Association Between Insulin Resistance Indices and Liver Function Parameters Among Women With Polycystic Ovary Syndrome
Naz, M. S. G., Mousavi, M. A., Firouzi, F., Momenan, A. A., Azizi, F., & Tehrani, F. R. (2024) · Endocrinology Diabetes & Metabolism · doi:10.1002/edm2.490 · Cited by 11
Causal Association Between BMI and Polycystic Ovarian Syndrome: Bidirectional 2-Sample Mendelian Randomization Study
Fang, Y., Liu, L., Yang, Y., Zhang, B., & Xie, S. (2024) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgae446 · Cited by 14
Breast Cancer Risk and Management in the Endocrine Clinic: A Comprehensive Review
Hawazie, A., & Druce, M. R. (2025) · Clinical Endocrinology · doi:10.1111/cen.15209 · Cited by 11
Ketone supplementation acutely lowers androgen and glucose levels in women with polycystic ovary syndrome: a randomized clinical trial
Rittig, N. F., Arlien-Søborg, M. C., Svart, M. V., Thomsen, H. H., Kirkegaard, K., Greve, V. H., Nielsen, M. M., Stochholm, K., Ørnstrup, M. J., & Gravholt, C. H. (2025) · European Journal of Endocrinology · doi:10.1093/ejendo/lvaf106 · Cited by 12
Salicylate administration suppresses the inflammatory response to nutrients and improves ovarian function in polycystic ovary syndrome
González, F., Mather, K. J., Considine, R. V., Abdelhadi, O. A., & Acton, A. J. (2020) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00228.2020 · Cited by 12
Bezafibrate Restores the Inhibition of FSH-Induced Follicular Development and Steroidogenesis by Tumor Necrosis Factor-Alpha Through Peroxisome Proliferator-Activated Receptor-Gamma Pathway in an In Vitro Mouse Preantral Follicle Culture1
Hara, S., Takahashi, T., Amita, M., Igarashi, H., Tsutsumi, S., & Kurachi, H. (2011) · Biology of Reproduction · doi:10.1095/biolreprod.111.090738 · Cited by 12
Creatine Kinase Is a Marker of Metabolic Syndrome in Qatari Women With and Without Polycystic Ovarian Syndrome
Al-Hail, N., Butler, A. E., Dargham, S. R., Seif, A. A., & Atkin, S. L. (2019) · Frontiers in Endocrinology · doi:10.3389/fendo.2019.00659 · Cited by 11
Association between VEGF gene polymorphisms (11 sites) and polycystic ovary syndrome risk
Huang, L., & Lunwen, W. (2020) · Bioscience Reports · doi:10.1042/bsr20191691 · Cited by 11
Obesity and Insulin Resistance, Not Polycystic Ovary Syndrome, Are Independent Predictors of Bone Mineral Density in Adolescents and Young Women
Pereira-Eshraghi, C., Chiuzan, C. C., Zhang, Y., Tao, R., McCann, M. R., Neugut, Y. D., Printz, A., Fennoy, I., Cree‐Green, M., Oberfield, S. E., et al. (2019) · Hormone Research in Paediatrics · doi:10.1159/000507079 · Cited by 11
The 6th Annual World Congress on the Insulin Resistance Syndrome
Bloomgarden, Z. T. (2009) · Diabetes Care · doi:10.2337/dc09-zb09 · Cited by 11
Association between β2‐adrenoceptor ( ADRB 2) haplotypes and insulin resistance in PCOS
Tellechea, M. L., Muzzio, D. O., Molli, A. E. I., Belli, S., Graffigna, M., Levalle, O. A., Frechtel, G. D., & Cerrone, G. E. (2012) · Clinical Endocrinology · doi:10.1111/cen.12019 · Cited by 12
Comparison of acupuncture pretreatment followed by letrozole versus letrozole alone on live birth in anovulatory infertile women with polycystic ovary syndrome: a study protocol for a randomised controlled trial
Li, J., Ng, E. H. Y., Stener‐Victorin, E., Hu, Z., Wu, W., Lai, M., Wu, T., & Ma, H. (2016) · BMJ Open · doi:10.1136/bmjopen-2015-010955 · Cited by 11
Reporting of ethnicity in research on chronic disease: update
O’Loughlin, J. L., Dugas, E. N., Maximova, K., & Kishchuk, N. A. (2006) · Postgraduate Medical Journal · doi:10.1136/pgmj.2005.048074 · Cited by 12
Faster thrombin generation in women with polycystic ovary syndrome compared with healthy controls matched for age and body mass index
de Mendonça-Louzeiro, M. R. M. F., Annichino‐Bizzacchi, J. M., Magna, L. A., Quaino, S. K. P., & Benetti‐Pinto, C. L. (2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2013.01.105 · Cited by 10
Surprisingly low infertility rate in married type 2 diabetic women: A rather curious paradox to the current opinion of insulin resistance as the joint pathogenesis of poly cystic ovary syndrome and type 2 diabetes mellitus
Arjmand, A. T., Nouri, M., & Tavakolian Arjmand, S. (2015) · Diabetes & Metabolic Syndrome Clinical Research & Reviews · doi:10.1016/j.dsx.2015.08.007 · Cited by 10
Assessment of atrial conduction time in patients with polycystic ovary syndrome
Zehi̇r, R., Karabay, C. Y., Kocabay, G., Kalaycı, A., Kaymaz, Ö., Aykan, A. Ç., Karabay, E., & Kırma, C. (2014) · Journal of Interventional Cardiac Electrophysiology · doi:10.1007/s10840-014-9925-8 · Cited by 10
The role of vitamin D deficiency in the etiology of polycystic ovary syndrome disorders
Brzozowska, M., & Karowicz-Bilińska, A. (2013) · Ginekologia Polska · doi:10.17772/gp/1604 · Cited by 10
Using metabolic markers to identify insulin resistance in premenopausal women with and without polycystic ovary syndrome
Blum, M. R., Popat, R. A., Nagy, A., Cataldo, N. A., & McLaughlin, T. (2021) · Journal of Endocrinological Investigation · doi:10.1007/s40618-020-01430-2 · Cited by 14
Knockdown of DPP4 promotes the proliferation and the activation of the CREB/aromatase pathway in ovarian granulosa cells
Lin, L., & Wang, L. (2022) · Molecular Medicine Reports · doi:10.3892/mmr.2022.12589 · Cited by 11
Lack of association of INS VNTR polymorphism with polycystic ovary syndrome: a meta-analysis
Song, L.-Y., Luo, J.-R., Peng, Q.-L., Wang, J., Xie, L., He, Y., Li, S., & Qin, X. (2014) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-014-0211-6 · Cited by 11
Androgen receptor actions on AgRP neurons are not a major cause of reproductive and metabolic impairments in peripubertally androgenized mice
Kerbus, R. I., Decourt, C., Inglis, M. A., Campbell, R. E., & Anderson, G. M. (2024) · Journal of Neuroendocrinology · doi:10.1111/jne.13370 · Cited by 9
Android fat distribution affects some hemostatic parameters in women with polycystic ovary syndrome compared with healthy control subjects matched for age and body mass index
de Mendonça-Louzeiro, M. R. M. F., Annichino‐Bizzacchi, J. M., & Benetti‐Pinto, C. L. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.05.013 · Cited by 9
Pharmacologic Treatments for PCOS Patients
Kodama, S., & Torrealday, S. (2020) · Clinical Obstetrics & Gynecology · doi:10.1097/grf.0000000000000597 · Cited by 10
Effects of a Lifestyle Intervention on Health-Promoting Behavior, Psychological Distress and Reproductive Health of Overweight and Obese Female College Students
Nho, J., & Chae, S. (2021) · Healthcare · doi:10.3390/healthcare9030309 · Cited by 9
Insulin Resistance in Polycystic Ovary Syndrome
Sung, Y. (2008) · Korean Diabetes Journal · doi:10.4093/kdj.2008.32.1.1 · Cited by 8
A randomized controlled trial of the effect of rosiglitazone and clomiphene citrate versus clomiphene citrate alone in overweight/obese women with polycystic ovary syndrome
Mohsen, I. A. (2011) · Gynecological Endocrinology · doi:10.3109/09513590.2011.614207 · Cited by 9
Treatment for polycystic ovary syndrome: a critical appraisal of treatment options
Nader, S. (2008) · Expert Review of Endocrinology & Metabolism · doi:10.1586/17446651.3.3.349 · Cited by 9
Definition, Diagnosis, and Epidemiology of the Polycystic Ovary Syndrome
Azziz, R. (2007) · Springer eBooks · doi:10.1007/978-0-387-69248-7_1 · Cited by 9
Self-citation
L’insulinorésistance biologique chez la femme congolaise avec syndrome des ovaires polymicrokystiques (SOPK)
Amisi, C. A., Mputu, L., Mboloko, E., Bieleli, E., & Pozzili, P. (2013) · Gynécologie Obstétrique & Fertilité · doi:10.1016/j.gyobfe.2013.08.002 · Cited by 9
Polycystic Ovary Syndrome and Ovulation Induction
Yildiz, B. O., & Azziz, R. (2007) · Humana Press eBooks · doi:10.1007/978-1-59745-179-6_35 · Cited by 9
Self-citation
Lifestyle changes in women with Polycystic Ovary Syndrome
Moran, L., Hutchison, S. K., Norman, R. J., & Teede, H. J. (2008) · Cochrane Database of Systematic Reviews · doi:10.1002/14651858.cd007506 · Cited by 10
Are Women with Polycystic Ovary Syndrome at Increased Risk of Alzheimer Disease? Lessons from Insulin Resistance, Tryptophan and Gonadotropin Disturbances and Their Link with Amyloid-Beta Aggregation
Sobczuk, J., Paczkowska, K., Andrusiów, S., Bolanowski, M., & Daroszewski, J. (2024) · Biomolecules · doi:10.3390/biom14080918 · Cited by 8
Comprehensive Management of Polycystic Ovary Syndrome: Effect of Pharmacotherapy, Lifestyle Modification, and Enhanced Adherence Counseling
Jungari, M. L., Choudhary, A., & Gill, N. K. (2023) · Cureus · doi:10.7759/cureus.35415 · Cited by 12
Factors Associated With Increased Carotid Intima-Media Thickness and Being Nondipper in Nonobese and Normotensive Young Patients Affected by PCOS
Ercan, E. A., Ertek, S., İş, G., Çağlar, O., Öztaş, E., Cicero, A. F. G., Alhan, A., Çehreli, Ş., Töre, H. F., & Erdoğan, G. (2011) · Angiology · doi:10.1177/0003319711400183 · Cited by 8
Massive Ovarian Growth in a Woman With Severe Insulin-Resistant Polycystic Ovary Syndrome Receiving GnRH Analogue
Singh, P., Agress, A., Madrigal, V., Magyar, C. E., Ostrzega, N. L., Chazenbalk, G. D., & Dumesic, D. A. (2019) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2018-02464 · Cited by 8
Autoimmune activation of the GnRH receptor induces insulin resistance independent of obesity in a female rat model
Li, H., Zhang, G., Guo, Y., Deng, J., Fischer, H., Craig, L. B., Kem, D. C., & Yu, X. (2020) · Physiological Reports · doi:10.14814/phy2.14672 · Cited by 7
Defining PCOS: A syndrome with an intrinsic heterogeneous nature
Escobar-Morreale, H. F. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-823045-9.00012-2 · Cited by 8
Ovarian follicle count by magnetic resonance imaging is greater in adolescents and young adults with polycystic ovary syndrome than in controls
Pereira-Eshraghi, C., Tao, R., Chiuzan, C. C., Zhang, Y., Shen, W., Lerner, J. P., Oberfield, S. E., & Sopher, A. B. (2022) · F&S Reports · doi:10.1016/j.xfre.2022.01.008 · Cited by 8
Establishment of polycystic ovary syndrome-derived human embryonic stem cell lines
Li, P., Wang, F., Kong, H., Zhao, F., Bai, A., Chen, X., & Sun, Y. (2011) · Gynecological Endocrinology · doi:10.3109/09513590.2011.588748 · Cited by 8
Association of MEP1A gene variants with insulin metabolism in central European women with polycystic ovary syndrome
Lam, U. D. P., Lerchbaum, E., Schweighofer, N., Trummer, O., Eberhard, K., Genser, B., Pieber, T. R., & Obermayer-Pietsch, B. M. (2014) · Gene · doi:10.1016/j.gene.2013.12.055 · Cited by 8
Insulin resistance and upper-body obesity in polycystic ovary syndrome
Al-Bayatti, A. A. (2007) · Bioline International (Bioline International) · Cited by 8
Single nucleotide polymorphisms in treatment of polycystic ovary syndrome: a systematic review
Deswal, R., Nanda, S., & Dang, A. S. (2019) · Drug Metabolism Reviews · doi:10.1080/03602532.2019.1667380 · Cited by 9
Novel Systematics of Nomenclature and Classification of Female Functional Androgenization (Including Polycystic Ovary Syndrome and Non-Classic Congenital Adrenal Hyperplasia)
Geisthövel, F., Wacker, A., Brabant, G. E., Botsch, F., Maechtel, A., Wetzka, B., & Ochsner, A. (2010) · Journal für Kardiologie (Krause & Pachernegg GmbH) · Cited by 8
Assessment of Clinical, Biochemical, and Hormonal Profile of Lean Versus Overweight Polycystic Ovarian Syndrome Patients
Ghatnatti, V., Patil, S., & Kour, H. (2022) · APIK Journal of Internal Medicine · doi:10.4103/ajim.ajim_117_20 · Cited by 7
Increased Ratio of Total Testosterone to Dihydrotestosterone May Predict an Adverse Metabolic Outcome in Polycystic Ovary Syndrome
Shah, S., Banu, H., Sultana, T., Akhtar, N., Begum, A., Zamila, B. M., Fariduddin, M., & Hasanat, M. A. (2019) · Journal of Endocrinology and Metabolism · doi:10.14740/jem601 · Cited by 7
The Efficacy and Safety of Dingkun Pill in Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Jin, B., Zhang, Y., Zhang, Z., Yang, G., Pan, Y., Xie, L., Liu, J., & Shen, W. (2022) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2022/8698755 · Cited by 7
Association between Adiponectin Receptor 1 Gene Polymorphism and Insulin Resistance in Chinese Patients with Polycystic Ovary Syndrome
Yang, Z., Yang, X., Xu, J., Sun, Y., Shi, Y., & Fang, S. (2013) · Gynecologic and Obstetric Investigation · doi:10.1159/000356960 · Cited by 7
Genetic variants of the HSD11B1 gene promoter may be protective against polycystic ovary syndrome
Grolmusz, V. K., Ács, O. D., Feldman, K., Szappanos, Á., Stenczer, B., Fekete, T., Szendei, G., Reismann, P., Rácz, K., & Patócs, A. (2014) · Molecular Biology Reports · doi:10.1007/s11033-014-3473-2 · Cited by 7
Effect of Lifestyle Modification and Metformin Therapy on Emerging Cardiovascular Risk Factors in Overweight Indian Women with Polycystic Ovary Syndrome
Rajagopal, G., Reddy, A., Harinarayan, C. V., Suresh, V., Bitla, A. R. R., Rao, S. P. V. L. N., & Sachan, A. (2012) · Metabolic Syndrome and Related Disorders · doi:10.1089/met.2011.0127 · Cited by 8
Triplet pregnancy after metformin in a woman with polycystic ovary syndrome
Clapauch, R., & Mattos, T. M. (2007) · Fertility and Sterility · doi:10.1016/j.fertnstert.2007.05.034 · Cited by 6
How medical treatment affects mean platelet volume as a cardiovascular risk marker in polycystic ovary syndrome?
Kucur, S. K., Gözükara, İ., Aksoy, A. N., Uludağ, E. Ü., Keskin, H., Kamalak, Z., & Çarlıoğlu, A. (2014) · Blood Coagulation & Fibrinolysis · doi:10.1097/mbc.0000000000000229 · Cited by 7
The relationship of serum 25-dihydroxy vitamin D3 concentrations with metabolic parameters in non-obese women with polycystic ovarian syndrome
Rashidi, H., Toolabi, M., Najafian, M., Sadrian, E., Safapoor, N., & Nazari, P. (2016) · Middle East Fertility Society Journal · doi:10.1016/j.mefs.2016.06.003 · Cited by 7
Is There Any Association Between Hirsutism and Serum Zinc Levels in Adolescents?
Aliyev, U., Kızılkan, M. P., Düzçeker, Y., Kanbur, N., Aycan, Z., Akgül, S., & Derman, O. (2020) · Biological Trace Element Research · doi:10.1007/s12011-020-02086-y · Cited by 7
Effects of Resveratrol on Metabolic, Biochemical, and Endocrine Manifestations in Polycystic Ovary Syndrome
Dubey, P., Shi, T., Coltharp, M., & Reddy, S. (2022) · Dietetics · doi:10.3390/dietetics1020008 · Cited by 7
Serum ferritin as a candidate diagnostic biomarker of polycystic ovarian syndrome: a meta-analysis
Tiongco, R. E., Rivera, N. S., Clemente, B., Dizon, D., Salita, C., & Pineda-Cortel, M. R. (2019) · Biomarkers · doi:10.1080/1354750x.2019.1620335 · Cited by 7
Age, Body Mass Index, and Waist-to-Hip Ratio Related Changes in Insulin Secretion and Insulin Sensitivity in Women with Polycystic Ovary Syndrome: Minimal Model Analyses
Šumarac-Dumanović, M., Stamenković-Pejković, D., Jeremić, D., Dumanović, J., Mandić, V., Žarković, M., & Micić, D. (2022) · International Journal of Endocrinology · doi:10.1155/2022/6630498 · Cited by 7
The presence of polycystic ovary syndrome increases the risk of maternal but not neonatal complications in women with type 2 diabetes in pregnancy
Atkins, P., TOMLINSON, G. A., Feig, D. S., & MiTy Collaborative Group (2023) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3713 · Cited by 7
Androgen-induced upregulation of CFTR in pancreatic β-cell contributes to hyperinsulinemia in PCOS model
Sun, M., Wu, Y., Yuan, C. L., Lyu, J., Zhao, X., Ruan, Y. C., Guo, J., Chen, H., & Huang, W. Q. (2023) · Endocrine · doi:10.1007/s12020-023-03516-2 · Cited by 7
Phenotypic Characterization of Polycystic Ovary Syndrome in Adolescents Based on Menstrual Irregularity
Javed, A., Kumar, S., Simmons, P. S., & Lteif, A. N. (2015) · Hormone Research in Paediatrics · doi:10.1159/000435883 · Cited by 6
Obesity in Polycystic Ovary Syndrome: Insulin Sensitizing Therapy
Hoeger, K. M. (2012) · Current Obesity Reports · doi:10.1007/s13679-012-0030-y · Cited by 6
ATP synthase β-subunit abnormality in pancreas islets of rats with polycystic ovary syndrome and type 2 diabetes mellitus
Li, W., Li, S., Yin, T., Yang, J., & Cheng, Y. (2017) · Journal of Huazhong University of Science and Technology [Medical Sciences] · doi:10.1007/s11596-017-1717-9 · Cited by 6
Polycystic Ovary Syndrome
Waldman, I. N., & Legro, R. S. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813209-8.00026-1 · Cited by 6
Medical journey of patients with polycystic ovary syndrome and obesity: a cross-sectional survey of patients and primary care physicians
Sherif, K., Coborn, J., Hoovler, A., & Gill, L. A. (2022) · Postgraduate Medicine · doi:10.1080/00325481.2022.2140511 · Cited by 7
Insulin Resistance and Lipotoxicity in PCOS: Causes and Consequences
Bellanger, S., Battista, M., & Baillargeon, J. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8394-6_7 · Cited by 5
Effects of Oral Contraceptives and Metformin on the Outcome of In Vitro Maturation in Infertile Women with Polycystic Ovary Syndrome
Zhao, J., Lin, J.-J., Yang, H., Zhang, W., Huang, X., & Huang, Y. (2010) · Journal of Women s Health · doi:10.1089/jwh.2009.1491 · Cited by 6
Síndrome de ovario poliquístico, endometrio y riesgo de aborto
Vivas, C. A. (2005) · Revista Colombiana de Obstetricia y Ginecología · doi:10.18597/rcog.519 · Cited by 6
The 6th Annual World Congress on the Insulin Resistance Syndrome
Bloomgarden, Z. T. (2009) · Diabetes Care · doi:10.2337/dc09-zb11 · Cited by 6
Characterization of distinct polycystic ovary syndrome subtypes by cluster and principal component analyses
Burns, K. A., Stuckey, A. W., Wilson, S. G., Watts, G. F., & Stuckey, B. G. A. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1572427 · Cited by 6
Insight into the pathogensis of polycystic ovarian syndrome
Jung, Y. W., Lee, G. H., Han, Y. J., & Cha, D. H. (2020) · Journal of genetic medicine · doi:10.5734/jgm.2020.17.1.1 · Cited by 5
Circulating HHIP Levels in Women with Insulin Resistance and PCOS: Effects of Physical Activity, Cold Stimulation and Anti-Diabetic Drug Therapy
Zhou, X., Wang, Y., Chen, W., Zhang, H., He, Y., Dai, H., Hu, W., Li, K., Zhang, L., Chen, C., et al. (2023) · Journal of Clinical Medicine · doi:10.3390/jcm12030888 · Cited by 5
Effect of oral glucose tolerance test-based insulin resistance on embryo quality in women with/without polycystic ovary syndrome
Hu, Z., Zeng, R., Tang, Y., Liao, Y., Li, T., & Qin, L. (2024) · Frontiers in Endocrinology · doi:10.3389/fendo.2024.1413068 · Cited by 6
Update on Polycystic Ovary Syndrome
Diamanti‐Kandarakis, E., & Panidis, D. (2006) · Women s Health · doi:10.2217/17455057.2.4.561 · Cited by 5
Polycystic Ovary Syndrome
Alwardi, A. S., AlKaban, R. A., & Abid, A. G. (2018) · International Journal of Advanced Research in Biological Sciences (IJARBS) · doi:10.22192/ijarbs.2018.05.07.004 · Cited by 5

Authors: DeUgarte, C. M., Bartolucci, A. A., & Azziz, R.
Affiliations: Cedars-Sinai Medical Center (US)
University of Alabama at Birmingham (US)
Corresponding author: Azziz, Ricardo
ORCID: Bartolucci, Alfred A.
Azziz, Ricardo
Venue: Fertility and Sterility
Publisher: Elsevier BV
Published: 2005-05
Volume: 83
Issue: 5
Pages: 1454-1460
ISSN: 0015-0282 (ISSN-L)
DOI: 10.1016/j.fertnstert.2004.11.070
OpenAlex: W2117559317
Cited by: 589
References: 62
Citations by year: 2026: 14 · 2025: 23 · 2024: 24 · 2023: 30 · 2022: 41 · 2021: 32 · 2020: 33 · 2019: 33 · 2018: 23 · 2017: 28 · 2016: 32 · 2015: 37 · 2014: 33 · 2013: 48 · 2012: 21
FWCI: 23.24
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 6235 d)
Locations: Fertility and Sterility (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetic and Kidney Cyst Diseases
Keywords: polycystic ovary syndrome, insulin resistance, HOMA-IR, beta-cell function, prevalence, obesity, sex hormones, insulin secretion
MeSH terms: Adult, Female, Homeostasis, Humans, Insulin Resistance, Middle Aged, Polycystic Ovary Syndrome, Prospective Studies, Prevalence, Chi-Square Distribution, Case-Control Studies

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Prevalence of insulin resistance in the polycystic ovary syndrome using the homeostasis model assessment

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks