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Congenital abnormalities in children born after assisted reproductive techniques: how much is associated with the presence of infertility and how much with its treatment?
Open accessAbstract
Although there is increasing evidence to link couples with infertility undergoing all assisted reproductive technologies, particularly intracytoplasmic sperm injection (ICSI), and congenital abnormalities, the reasons remain unclear. Much evidence suggests that infertility itself might be a risk factor, and further long-term follow-up studies involving different possible control groups will help determine whether these abnormalities are directly related to treatment.
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The control group in the ASRM abstract was composed of predominantly spontaneous conceptions, which are known to be associated with a lower risk of pregnancy complications and congenital malformations than an infertility population.
“First, the control group was composed of predominantly spontaneous conceptions, which are known to be associated with a lower risk of pregnancy complications and congenital malformations than an infertility population (18).”
From Congenital malformations among 911 newborns conceived after infertility treatment with letrozole or clomiphene citrate (2006) · cites this paper as [18]
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Metadata
- Authors
- Buckett, W. M., & Tan, S. L.
- Affiliations
- McGill University (CA)
- Corresponding author
- Buckett, William M.
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2005-11
- Volume
- 84
- Issue
- 5
- Pages
- 1318-1319
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W1964909047
- Cited by
- 28
- References
- 15
- Citations by year
- 2022: 1 · 2021: 1 · 2019: 1 · 2018: 2 · 2017: 1 · 2016: 2 · 2015: 2 · 2014: 2 · 2013: 2
- FWCI
- 2.60
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Assisted Reproductive Technology and Twin Pregnancy
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Keywords
- congenital malformations, assisted reproduction, infertility, intracytoplasmic sperm injection, infertility treatment, risk factors, long-term follow-up
- MeSH terms
- Congenital Abnormalities, Child, Female, Humans, Infertility, Male, Reproductive Techniques, Assisted
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