The DOI matches its Crossref record.
Barriers to conducting clinical research in reproductive medicine: Latin America
Open accessAbstract
Societies in Latin America are not scientifically driven and therefore, the allocation of human and economic resources to research is meager, as a reflection of this as well as other cultural and economic realities.
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Delays in regulatory and ethical review were mentioned in most articles.
“Delays in regulatory and ethical review were mentioned in most articles [40, 42, 45, 46, 48, 49, 52].”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [45]
Four articles reported that the presence of unskilled authorities in the review process posed a barrier to conducting clinical trials.
“Four articles reported that the presence of unskilled authorities in the review process posed a barrier to conducting clinical trials [42, 45, 48, 49].”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [45]
The majority of articles stated that the administrative environment was characterized by lengthy and complex logistic and financial systems that hampered the conduct of clinical trials.
“The majority of the articles [43, 45, 47, 48, 51, 52] stated that the administrative environment was characterized by lengthy and complex logistic and financial systems that hampered the conduct of clinical trials.”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [45]
Many articles reported that lack of time and other competing priorities related to competing demands of working multiple jobs and their attendant responsibilities was an issue.
“Many articles reported that lack of time [40, 48, 51, 53] and other competing priorities related to the competing demands of working multiple jobs and their attendant responsibilities [40, 43, 45, 46, 48, 51, 53] was an issue.”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [45]
Absence of suitable research infrastructure was stated by many articles.
“Absence of suitable research infrastructure was stated by many articles [45, 47–50].”
From Barriers for conducting clinical trials in developing countries—A systematic review (2018) · cites this paper as [45]
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Barriers for conducting clinical trials in developing countries—A systematic review
Alemayehu, C., Mitchell, G., & Nikles, J. (2018) · International Journal for Equity in Health · doi:10.1186/s12939-018-0748-6 · Cited by 406
“Many articles reported that lack of time [40, 48, 51, 53] and other competing priorities related to the competing demands of working multiple jobs and their attendant responsibilities [40, 43, 45, 46, 48, 51, 53] was an issue.”
BackgroundInfluentialMotives for participating in a clinical research trial: a pilot study in Brazil
Nappo, S. A., Iafrate, G. B., & Sanchez, Z. M. (2013) · BMC Public Health · doi:10.1186/1471-2458-13-19 · Cited by 79
“The basic principles of bioethics (autonomy, beneficence, non-maleficence and justice) [10] may be violated in clinical studies on human subjects in such developing countries as Brazil and may be a source of bias within the study [11].”
BackgroundVeziari, Y., Kumar, S., & Leach, M. (2021) · BMC Complementary Medicine and Therapies · doi:10.1186/s12906-021-03371-6 · Cited by 36
Gómez, H., Pinto, J. A., Castañeda, C. A., & Vallejos, C. S. (2015) · Clinical Research and Trials · doi:10.15761/crt.1000108 · Cited by 20
“In other medical science disciplines, there are opinions that societies are not scientifically conducted and that the allocation of human and economic resources to research is meagre [15].”
BackgroundAbuses and Apologies: Irresponsible Conduct of Human Subjects Research in Latin America
Aultman, J. M. (2013) · The Journal of Law Medicine & Ethics · doi:10.1111/jlme.12025 · Cited by 10
Randomised clinical trials in surgery: are we at a crossroads?
Ramchurn, T. P., & Nundy, S. (2023) · Annals of Medicine and Surgery · doi:10.1097/ms9.0000000000001457 · Cited by 7
“Some of the challenges facing researchers in developing countries are: lack of funding [24 – 35] , lack of skilled personnel [24,26,28,29] , complex and strict ethical and regulatory frameworks [32,35,36] , lack of research environment [29,34] , and competing demands (lack of time) of health…”
BackgroundParedes, R., Karol, A. B., Markus, A., Argulian, A., Omori, R., Fujiwara, Y., Joshi, H. N., Doroshow, D. B., & Galsky, M. D. (2026) · JCO Global Oncology · doi:10.1200/go-25-00411 · Cited by 1
González‐Santos, S. P. (2019) · Springer eBooks · doi:10.1007/978-3-030-23041-8_5
Contesting the ‘No Rules’ Label
González‐Santos, S. P., & Saldaña‐Tejeda, A. (2023) · doi:10.1093/oso/9780197616192.003.0008
Metadata
- Authors
- Zegers-Hochschild, F.
- Affiliations
- Clínica Las Condes (CL)
- Corresponding author
- Zegers-Hochschild, Fernando
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2011-10
- Volume
- 96
- Issue
- 4
- Pages
- 802-804
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2074764333
- Cited by
- 9
- References
- 0
- Citations by year
- 2026: 1 · 2023: 2 · 2021: 1 · 2019: 1 · 2018: 1 · 2015: 1 · 2013: 2
- FWCI
- 0.63
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- DigitalGeorgetown (Georgetown University Library) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health and Medical Research Impacts
- Social Sciences › Demography › Science, Technology, and Education in Latin America
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Keywords
- research funding, research resource allocation, Latin America
- MeSH terms
- Animals, Communication Barriers, Educational Status, Humans, Latin America, Religion, Research Support as Topic, Multicenter Studies as Topic, Reproductive Medicine, Biomedical Research
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