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Cited by 20Ovarian function and disordersCardiovascular Function and Risk FactorsDiabetes, Cardiovascular Risks, and Lipoproteins

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Blood pressure regulation and resting heart rate abnormalities in adolescent girls with polycystic ovary syndrome

Open access
Zachurzok-Buczynska, Agnieszka, Szydlowski, Leslaw, Gawlik, Aneta, Wilk, Krzysztof, Malecka-Tendera, Ewa·2011·Fertility and Sterility
DOI 10.1016/j.fertnstert.2011.09.043
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Abstract

Objective To assess the risk of cardiovascular disease on the basis of biochemical, echocardiographic, and 24-hour blood pressure (BP) monitoring parameters in adolescent girls with polycystic ovary syndrome (PCOS). Design Cross-sectional study. Setting Academic and research institution. Patient(s) Thirty-four obese and nonobese girls with PCOS were evaluated and compared with body mass index-matched girls with regular menses. Intervention(s) None. Main outcome measure(s) Androgens, gonadotropins, lipids, and fasting and oral glucose tolerance test-stimulated glucose and insulin concentrations were measured. Echocardiographic assessment and 24-hour BP monitoring were done. Result(s) Compared with obese controls, obese girls with PCOS had significantly higher 24-hour mean BP, day mean BP, day diastolic BP, and diastolic BP nighttime dip (75.5 ± 4.5 mm Hg vs. 71.7 ± 3.7 mm Hg; 78.2 ± 5.0 mm Hg vs. 73.6 ± 4.0 mm Hg; 67.6 ± 4.9 mm Hg vs. 63.7 ± 3.7 mm Hg; and 20.2% ± 5.2% vs. 15.0% ± 6.6%, respectively). Obese girls with PCOS had significantly higher night heart rate than obese controls (60.4 ± 5.6 beats per minute vs. 61.7 ± 4.8 beats per minute). Left ventricle end-diastolic (4.6 ± 0.3 cm vs. 4.2 ± 0.2 cm) and end-systolic diameter (3.0 ± 0.3 cm vs. 2.7 ± 0.2 cm) were also significantly higher in nonobese girls with PCOS than in nonobese controls; however, all values were still within the accepted range of normal limits. Conclusion(s) Higher night heart rate in obese girls with PCOS and higher day BP but preserved diastolic nocturnal dip in nonobese girls with PCOS may be regarded as early cardiovascular disease risk factors.

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Crossref · 10.1016/j.fertnstert.2011.09.043

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  • Ten studies included information regarding the use of wearables.

    “Ten studies included information regarding the use of wearables [77,78,79,80,81,82,83,84,85,86] (Supplementary File S3).”

    From Polycystic Ovary Syndrome and the Internet of Things: A Scoping Review (2024) · cites this paper as [83]

  • Adolescents with PCOS, particularly those with obesity, may present asymptomatic adverse alterations (e.g., in blood pressure and resting heart rate), which are considered early cardiovascular disease risk factors.

    “Adolescents with PCOS, particularly those with obesity, may present asymptomatic adverse alterations (e.g., in blood pressure and resting heart rate), which are considered early cardiovascular disease risk factors [83].”

    From Polycystic Ovary Syndrome and the Internet of Things: A Scoping Review (2024) · cites this paper as [83]

  • Wearables used included activity trackers, sleep monitors, 24-h blood pressure monitors, and more invasive ones inserted into the abdominal interstitial tissue for continuous glucose monitoring.

    “Wearables used included activity trackers [78,79,82], sleep monitors [77,80], 24-h blood pressure monitors [83], and more invasive ones inserted into the abdominal interstitial tissue for continuous glucose monitoring [81,84,85,86].”

    From Polycystic Ovary Syndrome and the Internet of Things: A Scoping Review (2024) · cites this paper as [83]

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Research works printed but not linked: 26

  1. Talbott, 2001, Cardiovascular risk in women with polycystic ovary syndrome, Obstet Gynecol Clin North Am, 28, 111, 10.1016/S0889-8545(05)70189-3 · DOI
  2. Arslanian, 2001, Glucose intolerance in obese adolescents with polycystic ovary syndrome: roles of insulin resistance and beta-cell dysfunction and risk of cardiovascular disease, J Clin Endocrinol Metab, 86, 66
  3. Talbott, 1995, Coronary heart disease risk factor in women with polycystic ovary syndrome, Arterioscler Thromb Vasc Biol, 15, 821, 10.1161/01.ATV.15.7.821 · DOI
  4. Ibanez, 2000, Sensitization to insulin in adolescent girls to normalize hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism after precocious pubarche, J Clin Endocrinol Metab, 85, 3526
  5. Kelly, 2002, Altered vascular function in young women with polycystic ovary syndrome, J Clin Endocrinol Metab, 87, 742, 10.1210/jcem.87.2.8199 · DOI
  6. Orio, 2004, The cardiovascular risk of young women with polycystic ovary syndrome: an observational, analytical, prospective case-control study, J Clin Endocrinol Metab, 89, 3696, 10.1210/jc.2003-032049 · DOI
  7. Christian, 2003, Prevalence and predictors of coronary artery calcification in women with polycystic ovary syndrome, J Clin Endocrinol Metab, 88, 2562, 10.1210/jc.2003-030334 · DOI
  8. Wild, 2000, Cardiovascular disease in women with polycystic ovary syndrome at long-term follow-up: a retrospective cohort study, Clin Endocrinol (Oxf), 52, 595, 10.1046/j.1365-2265.2000.01000.x · DOI · Paper page
  9. Arslanian, 2002, Polycystic ovary syndrome in adolescents: is there an epidemic?, Endocrinol Diabetes, 9, 32
  10. Ibanez, 1999, Endocrinology and metabolism after premature pubarche in girls, Acta Paediatr Suppl, 433, 73
  11. Azziz, 2009, The Androgen Excess and PCOS Society criteria for the polycystic ovary syndrome: the complete task force report, Fertil Steril, 91, 456, 10.1016/j.fertnstert.2008.06.035 · DOI · Paper page
  12. Cutfield, 2003, Evaluation of HOMA and QUICKI as measures of insulin sensitivity in prepubertal children, Pediatr Diabetes, 4, 119, 10.1034/j.1399-5448.2003.t01-1-00022.x · DOI
  13. Friedewald, 1972, Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge, Clin Chem, 18, 499, 10.1093/clinchem/18.6.499 · DOI · Paper page
  14. Teicholz, 1976, Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence or absence of asynergy, Am J Cardiol, 37, 7, 10.1016/0002-9149(76)90491-4 · DOI
  15. Palczewska, 2002, Evaluation of somatic development in children and adolescents [in Polish], Medycyna Praktyczna Pediatria, 3, 1
  16. Eidem, 2004, Impact of cardiac growth on Doppler tissue imaging velocities: a study in healthy children, J Am Soc Echocariogr, 17, 212, 10.1016/j.echo.2003.12.005 · DOI
  17. Reaven, 1988, Banting lecture 1988. Role of insulin resistance in human disease, Diabetes, 37, 1595, 10.2337/diab.37.12.1595 · DOI · Paper page
  18. Coviello, 2006, Adolescent girls with polycystic ovary syndrome have an increased risk of the metabolic syndrome associated with increasing androgen levels independent of obesity and insulin resistance, J Clin Endocrinol Metab, 91, 492, 10.1210/jc.2005-1666 · DOI
  19. Rossi, 2008, Prevalence of metabolic syndrome and related characteristics in obese adolescents with and without polycystic ovary syndrome, J Clin Endocrinol Metab, 93, 4780, 10.1210/jc.2008-1198 · DOI · Paper page
  20. Lewy, 2001, Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome, J Pediatr, 138, 38, 10.1067/mpd.2001.109603 · DOI · Paper page
  21. Battaglia, 2008, Vascular risk in young women with polycystic ovary and polycystic ovary syndrome, Obstet Gynecol, 111, 385, 10.1097/01.AOG.0000296657.41236.10 · DOI
  22. Holte, 1996, Elevated ambulatory day-time blood pressure in women with polycystic ovary syndrome: a sign of a pre-hypertensive state?, Hum Reprod, 11, 23, 10.1093/oxfordjournals.humrep.a019028 · DOI
  23. Zimmermann, 1992, Polycystic ovary syndrome: lack of hypertension despite profound insulin resistance, J Clin Endocrinol Metab, 75, 508
  24. Iqbal, 2010, Cardiovascular outcomes in patients with normal and abnormal 24-hour ambulatory blood pressure monitoring, Int J, 2011, 786912
  25. Fox, 2008, Resting heart rate in cardiovascular disease, J Am Coll Cardiol, 51, 330, 10.1016/j.jacc.2007.09.040 · DOI
  26. Luque-Ramírez, 2007, Obesity is the major determinant of the abnormalities in blood pressure found in young women with the polycystic ovary syndrome, J Clin Endocrinol Metab, 92, 2141, 10.1210/jc.2007-0190 · DOI

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Metadata

Authors
Zachurzok-Buczynska, A., Szydlowski, L., Gawlik, A., Wilk, K., & Malecka-Tendera, E.
Affiliations
Medical University of Silesia (PL)
ORCID
Gawlik, Aneta
Venue
Fertility and Sterility
Publisher
Elsevier BV
Published
2011-12
Volume
96
Issue
6
Pages
1519-1525
ISSN
0015-0282 (ISSN-L)
DOI
10.1016/j.fertnstert.2011.09.043
OpenAlex
W1999017576
Cited by
20
References
0
Citations by year
2026: 1 · 2024: 2 · 2023: 3 · 2021: 1 · 2018: 2 · 2017: 2 · 2016: 1 · 2015: 3 · 2013: 3 · 2012: 2
FWCI
1.79
Type
journal article
Language
en
Open access
Licence
Locations
  • Fertility and Sterility (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Reproductive Medicine › Ovarian function and disorders
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Function and Risk Factors
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
Keywords
polycystic ovary syndrome, adolescent girls, blood pressure, resting heart rate, cardiovascular risk, obesity, nocturnal blood pressure dipping, left ventricular dimensions, androgens, insulin resistance, dyslipidemia, gonadotropins
MeSH terms
Adolescent, Blood Glucose, Blood Pressure, Cardiovascular Diseases, Child, Cross-Sectional Studies, Female, Glucose Tolerance Test, Heart Rate, Humans, Insulin, Monitoring, Physiologic, Obesity, Polycystic Ovary Syndrome, Rest, Risk Factors, Body Mass Index

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