The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
Beyond infertility: obstetrical and postpartum complications associated with endometriosis and adenomyosis
Open accessAbstract
The risk of pregnancy and neonatal complications in women with endometriosis and adenomyosis is debatable. A literature review looking at rates, presentation, and management of spontaneous hemoperitoneum, enlargement, abscess, and rupture of an endometrioma, uterine rupture, and bowel perforation in pregnant women with endometriosis was conducted. Moreover, studies addressing differences in early pregnancy (miscarriage), late pregnancy (gestational diabetes mellitus, preeclampsia, prematurity, placenta previa, placental abruption, cesarean section, hemorrhages) and neonatal outcomes (weight at birth) between endometriosis and adenomyosis patients versus control subjects were reviewed. The overall prevalence of endometriosis-related spontaneous hemoperitoneum in pregnancy is estimated to be ∼0.4%. Only four cases of endometrioma rupture in pregnancy have been reported. Although during pregnancy there is no way to anticipate the onset of complications from preexisting endometriosis, it is important, when a specific abdominal pain occurs, to suspect rare but potentially life-threating events. Population-based studies suggest a possible association of endometriosis with preterm birth and placenta previa. Limits of the published studies are noted and discussed.
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“AM-associated disruption of the junctional zone and the inner myometrium may lead to placental implantation disorders [29,30,31,32].”
From Women with Endometriosis—Who Is at Risk for Complications Associated with Pregnancy and Childbirth? A Retrospective Case–Control Study (2024) · cites this paper as [31]
In the citing paper
“Instead of becoming at rest during a pregnancy, some deep lesions do progress and can cause bowel (65,66), uterus, or bladder perforations.”
From Pathogenesis of deep endometriosis (2017) · cites this paper as [66]
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Citations
Cites
Endometriosis: pathogenesis and treatment
Vercellini, P., Viganò, P., Somigliana, E., & Fedele, L. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.255 · Cited by 1,940
Eskenazi, B., & Warner, M. L. (1997) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(05)70302-8 · Cited by 1,617
Mechanisms of implantation: strategies for successful pregnancy
Cha, J., Sun, X., & Dey, S. K. (2012) · Nature Medicine · doi:10.1038/nm.3012 · Cited by 1,391
Endometriosis: pathogenetic implications of the anatomic distribution.
Jenkins, S., Olive, D. L., & Haney, A. F. (1986) · PubMed · Cited by 523
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis
Vercellini, P., Consonni, D., Dridi, D., Bracco, B., Frattaruolo, M. P., & Somigliana, E. (2014) · Human Reproduction · doi:10.1093/humrep/deu041 · Cited by 411
Kunz, G., Beil, D., Huppert, P., Noe, M., Kissler, S., & Leyendecker, G. (2005) · Human Reproduction · doi:10.1093/humrep/dei021 · Cited by 377
Bazot, M., Fiori, O., & Daraï, É. (2006) · Human Reproduction · doi:10.1093/humrep/dei448 · Cited by 283
Structural and molecular features of the endomyometrium in endometriosis and adenomyosis
Benagiano, G., Brosens, I., & Habiba, M. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmt052 · Cited by 246
Healy, D. L., Breheny, S., Halliday, J. L., Jaques, A., Rushford, D., Garrett, C., Talbot, J. M., & Baker, H. W. G. (2009) · Human Reproduction · doi:10.1093/humrep/dep376 · Cited by 240
Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome
Stephansson, O., Kieler, H., Granath, F., & Falconer, H. (2009) · Human Reproduction · doi:10.1093/humrep/dep186 · Cited by 234
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Gruber, T. M., Ebeling, G., Henrich, W., & Mechsner, S. (2026) · Frontiers in Endocrinology · doi:10.3389/fendo.2026.1718224
“The in fl uence of EM and AM on pregnancy and its outcome remains to be elucidated, but a growing body of evidence suggests that pregnant women with EM and AM may experience complications during late pregnancy and childbirth (3).”
Rees, C. O., Gabriels, E., Weyers, S., Siebers, A. G., Westerhuis, M. E. M. H., Schoot, B. C., & van Vliet, H. (2026) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2026.115434
Metadata
- Authors
- Vigano, P., Corti, L., & Berlanda, N.
- Affiliations
- IRCCS Ospedale San Raffaele (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 104
- Issue
- 4
- Pages
- 802-812
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2149590430
- Cited by
- 103
- References
- 85
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 3 · 2023: 15 · 2022: 7 · 2021: 14 · 2020: 10 · 2019: 8 · 2018: 11 · 2017: 12 · 2016: 11 · 2015: 1
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Zenodo (CERN European Organization for Nuclear Research) (other-oa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Keywords
- endometriosis, adenomyosis, pregnancy complications, spontaneous hemoperitoneum, uterine rupture, intestinal perforation, miscarriage, gestational diabetes mellitus, preeclampsia, preterm birth, placenta previa, placental abruption, cesarean section, neonatal outcomes, postpartum complications
- MeSH terms
- Endometriosis, Female, Hemoperitoneum, Humans, Infant, Newborn, Infertility, Ovarian Diseases, Peritoneal Diseases, Pregnancy, Pregnancy Complications, Puerperal Disorders, Postpartum Period, Adenomyosis
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