The DOI matches its Crossref record; 85 of the 85 references it cites were found in a registry or an index.
Beyond infertility: obstetrical and postpartum complications associated with endometriosis and adenomyosis
Open accessAbstract
The risk of pregnancy and neonatal complications in women with endometriosis and adenomyosis is debatable. A literature review looking at rates, presentation, and management of spontaneous hemoperitoneum, enlargement, abscess, and rupture of an endometrioma, uterine rupture, and bowel perforation in pregnant women with endometriosis was conducted. Moreover, studies addressing differences in early pregnancy (miscarriage), late pregnancy (gestational diabetes mellitus, preeclampsia, prematurity, placenta previa, placental abruption, cesarean section, hemorrhages) and neonatal outcomes (weight at birth) between endometriosis and adenomyosis patients versus control subjects were reviewed. The overall prevalence of endometriosis-related spontaneous hemoperitoneum in pregnancy is estimated to be ∼0.4%. Only four cases of endometrioma rupture in pregnancy have been reported. Although during pregnancy there is no way to anticipate the onset of complications from preexisting endometriosis, it is important, when a specific abdominal pain occurs, to suspect rare but potentially life-threating events. Population-based studies suggest a possible association of endometriosis with preterm birth and placenta previa. Limits of the published studies are noted and discussed.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“AM-associated disruption of the junctional zone and the inner myometrium may lead to placental implantation disorders [29,30,31,32].”
From Women with Endometriosis—Who Is at Risk for Complications Associated with Pregnancy and Childbirth? A Retrospective Case–Control Study (2024) · cites this paper as [31]
In the citing paper
“Instead of becoming at rest during a pregnancy, some deep lesions do progress and can cause bowel (65,66), uterus, or bladder perforations.”
From Pathogenesis of deep endometriosis (2017) · cites this paper as [66]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Endometriosis: pathogenesis and treatment
Vercellini, P., Viganò, P., Somigliana, E., & Fedele, L. (2014) · Nature Reviews Endocrinology · doi:10.1038/nrendo.2013.255 · Cited by 1,940
Eskenazi, B., & Warner, M. L. (1997) · Obstetrics and Gynecology Clinics of North America · doi:10.1016/s0889-8545(05)70302-8 · Cited by 1,617
Mechanisms of implantation: strategies for successful pregnancy
Cha, J., Sun, X., & Dey, S. K. (2012) · Nature Medicine · doi:10.1038/nm.3012 · Cited by 1,391
Endometriosis: pathogenetic implications of the anatomic distribution.
Jenkins, S., Olive, D. L., & Haney, A. F. (1986) · PubMed · Cited by 523
Uterine adenomyosis and in vitro fertilization outcome: a systematic review and meta-analysis
Vercellini, P., Consonni, D., Dridi, D., Bracco, B., Frattaruolo, M. P., & Somigliana, E. (2014) · Human Reproduction · doi:10.1093/humrep/deu041 · Cited by 411
Kunz, G., Beil, D., Huppert, P., Noe, M., Kissler, S., & Leyendecker, G. (2005) · Human Reproduction · doi:10.1093/humrep/dei021 · Cited by 377
Bazot, M., Fiori, O., & Daraï, É. (2006) · Human Reproduction · doi:10.1093/humrep/dei448 · Cited by 283
Structural and molecular features of the endomyometrium in endometriosis and adenomyosis
Benagiano, G., Brosens, I., & Habiba, M. (2014) · Human Reproduction Update · doi:10.1093/humupd/dmt052 · Cited by 246
Healy, D. L., Breheny, S., Halliday, J. L., Jaques, A., Rushford, D., Garrett, C., Talbot, J. M., & Baker, H. W. G. (2009) · Human Reproduction · doi:10.1093/humrep/dep376 · Cited by 240
Endometriosis, assisted reproduction technology, and risk of adverse pregnancy outcome
Stephansson, O., Kieler, H., Granath, F., & Falconer, H. (2009) · Human Reproduction · doi:10.1093/humrep/dep186 · Cited by 234
Flagged first, then by citations
Cited by
Sorted by citations
Zondervan, K. T., Becker, C. M., Koga, K., Missmer, S. A., Taylor, R. N., & Viganò, P. (2018) · Nature Reviews Disease Primers · doi:10.1038/s41572-018-0008-5 · Cited by 1,257
Pathogenesis of endometriosis: The genetic/epigenetic theory
Koninckx, P. R., Ussia, A., Adamyan, L., Wattiez, A., Gomel, V., & Martin, D. C. (2019) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.10.013 · Cited by 427
“Bowel perforations have been reported during pregnancy (66, 67) and estrogen-progestin treatment (68).”
BackgroundHorton, J., Sterrenburg, M. D., Lane, S. I. R., Maheshwari, A., Li, T. C., & Cheong, Y. C. (2019) · Human Reproduction Update · doi:10.1093/humupd/dmz012 · Cited by 387
Is the oocyte quality affected by endometriosis? A review of the literature
Sanchez, A. M., Vanni, V. S., Bartiromo, L., Papaleo, E., Zilberberg, E., Candiani, M., Orvieto, R., & Viganò, P. (2017) · Journal of Ovarian Research · doi:10.1186/s13048-017-0341-4 · Cited by 257
Pathogenesis of deep endometriosis
Gordts, S., Koninckx, P., & Brosens, I. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.08.036 · Cited by 241
Association of endometriosis and adenomyosis with pregnancy and infertility
Vercellini, P., Viganò, P., Bandini, V., Buggio, L., Berlanda, N., & Somigliana, E. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.03.018 · Cited by 249
Hashimoto, A., Iriyama, T., Sayama, S., Nakayama, T., Komatsu, A., Miyauchi, A., Nishii, O., Nagamatsu, T., Osuga, Y., & Fujii, T. (2018) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2017.1285895 · Cited by 141
“However, only a limited number of studies have reported on pregnancies complicated by adenomyosis and the associations between adenomyosis and perinatal outcomes have not been thoroughly investigated [3].”
BackgroundCurrent Medical Therapy for Adenomyosis: From Bench to Bedside
Etrusco, A., Barra, F., Chiàntera, V., Ferrero, S., Bogliolo, S., Evangelisti, G., Oral, E., Pastore, M., Izzotti, A., Venezia, R., et al. (2023) · Drugs · doi:10.1007/s40265-023-01957-7 · Cited by 125
“It is already known that adenomyosis has adverse obstetric effects such as premature birth, preterm rupture of the membranes, and live birth rate [100].”
BackgroundDueholm, M. (2017) · Acta Obstetricia et Gynecologica Scandinavica · doi:10.1111/aogs.13158 · Cited by 113
Exacoustos, C., Lauriola, I., Lazzeri, L., De Felice, G., & Zupi, E. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.06.024 · Cited by 100
Adenomyosis and Infertility—Review of Medical and Surgical Approaches
Szubert, M., Koziróg, E., Olszak, O., Krygier-Kurz, K., Kaźmierczak, J., & Wilczyński, J. R. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph18031235 · Cited by 99
“In addition, adenomyosis enhances the risk of obstetric complications, such as premature birth and preterm rupture of the amniotic membranes [18,19].”
BackgroundPregnancy outcome in women with endometriosis achieving pregnancy with IVF
Benaglia, L., Candotti, G., Papaleo, E., Pagliardini, L., Leonardi, M., Reschini, M., Quaranta, L., Munaretto, M., Viganò, P., Candiani, M., et al. (2016) · Human Reproduction · doi:10.1093/humrep/dew210 · Cited by 95
“Some recent epidemiological studies actually supported this possibility (Viganò et al., 2015: Leone Roberti Maggiore et al., 2016).”
BackgroundResultInfluentialLier, M. C. I., Malik, R. F., Ket, J. C. F., Lambalk, C. B., Brosens, I. A., & Mijatovic, V. (2017) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2017.10.012 · Cited by 97
Bruun, M. R., Arendt, L. H., Forman, A., & Ramlau‐Hansen, C. H. (2018) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1111/aogs.13364 · Cited by 80
“It has been suggested that both endometriosis and adenomyosis could be associated with obstetrical complications (8), and speculation on whether adenomyosis poses a larger threat to the pregnancy exist.”
BackgroundBurghaus, S., Schäfer, S. D., Beckmann, M. W., Brandes, I., Brünahl, C., Chvatal, R., Drahoňovský, J., Dudek, W., Ebert, A. D., Fahlbusch, C., et al. (2021) · Geburtshilfe und Frauenheilkunde · doi:10.1055/a-1380-3693 · Cited by 69
“3 Endometriose: Schwangerschaft und Geburt Bezüglich der Schwangerschaft existiert inzwischen eine größere Anzahl an Studien, die eine erhöhte Risikokonstellation wie folgt darstellt: ▪ Abortrate [28] ▪ Frühgeburtlichkeit [29] ▪ vorzeitiger Blasensprung [30] ▪ vorzeitige Plazentalösung [31] ▪ Placenta praevia [31] ▪ P…”
BackgroundEffect of aromatherapy on post-partum complications: A systematic review
Keikhaie, K. R., Hastings‐Tolsma, M., Bouya, S., Shad, F. S., Sari, M., Shoorvazi, M., Younes-Barani, Z., & Balouchi, A. (2019) · Complementary Therapies in Clinical Practice · doi:10.1016/j.ctcp.2019.03.010 · Cited by 65
Villette, C., Bourret, A., Santulli, P., Gayet, V., Chapron, C., & de Ziegler, D. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.04.014 · Cited by 59
Endometriosis, especially mild disease: a risk factor for miscarriages
Kohl Schwartz, A. S., Wölfler, M. M., Mitter, V., Rauchfuss, M., Haeberlin, F., Eberhard, M., von Orelli, S., Imthurn, B., Imesch, P., Fink, D., et al. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.08.025 · Cited by 63
“It has been shown that phenotypic classification corresponds better to the 246 obstetric outcome than the rASRM classification (42,43).”
A Relationship Between Endometriosis and Obstetric Complications
Kobayashi, H., Kawahara, N., Ogawa, K., & Yoshimoto, C. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00118-0 · Cited by 57
“Endometriosis significantly increased the incidence of preterm birth [6–12, 24–27, 31–36], miscarriage [13, 34], preterm premature rupture of membranes [8, 10, 32], placenta previa [7, 9, 11, 14, 32, 34, 35], preeclampsia [7, 10, 27, 32, 36], pregnancy-induced hypertension (PIH) [6, 7, 31, 32], gestational diabetes [8…”
BackgroundObstetrical complications of endometriosis, particularly deep endometriosis
Leone Roberti Maggiore, U., Inversetti, A., Schimberni, M., Viganò, P., Giorgione, V., & Candiani, M. (2017) · Fertility and Sterility · doi:10.1016/j.fertnstert.2017.10.035 · Cited by 60
Endometriosis and Pregnancy: A Single Institution Experience
Porpora, M. G., Tomao, F., Ticino, A., Piacenti, I., Scaramuzzino, S., Simonetti, S., Imperiale, L., Sangiuliano, C., Masciullo, L., Manganaro, L., et al. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17020401 · Cited by 47
“Complications of preexisting endometriotic foci during pregnancy are rare [46]; in our study, we observed one case of hemoperitoneum due to probable rupture of an ovarian endometrioma in the third trimester of pregnancy.”
BackgroundRiemma, G., FRANCISCIS, P. D., Verde, M. L., Ravo, M., Fumiento, P., Fasulo, D. D., Corte, L. D., Ronsini, C., Torella, M., & Cobellis, L. (2022) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.14621 · Cited by 43
Vercellini, P. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.09.004 · Cited by 40
Maternal and neonatal outcomes in women with colorectal endometriosis
Thomin, A., Belghiti, J., David, C., Marty, O., Bornes, M., Ballester, M., Roman, H., & Daraï, E. (2018) · BJOG: An International Journal of Obstetrics & Gynaecology · doi:10.1111/1471-0528.14221 · Cited by 39
Impact of endometriosis on obstetric outcome after natural conception: a multicenter Italian study
Berlanda, N., Alio, W., Angioni, S. L., Bergamini, V., Bonin, C., Boracchi, P., Candiani, M., Centini, G., D’Alterio, M. N., Forno, S. D., et al. (2021) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-021-06243-z · Cited by 35
Epidemiology of subtle, typical, cystic, and deep endometriosis: a systematic review
Koninckx, P. R., Ussia, A., Keckstein, J., Wattiez, A., & Adamyan, L. (2016) · Gynecological Surgery · doi:10.1007/s10397-016-0970-4 · Cited by 30
Obstetrical complications and outcome in patients with endometriosis
Borisova, A. V., Konnon, S. R., Tosto, V., Gerli, S., & Radzinsky, V. E. (2020) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2020.1793326 · Cited by 32
Shi, J., Dai, Y., Zhang, J., Li, X., Jia, S., & Leng, J. (2021) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-021-03851-0 · Cited by 30
“Two other systematic reviews failed to draw conclusions on obstetrical complications related to EM except for preterm delivery [34] and placenta previa [35].”
BackgroundKobayashi, H., Yoshimoto, C., Matsubara, S., Shigetomi, H., & Imanaka, S. (2023) · Diagnostics · doi:10.3390/diagnostics13111926 · Cited by 36
“Collectively, the high iron content of ovarian endometriomas adversely affects the adjacent granulosa cells through oxidative stress by free iron-mediated Fenton reactions, reducing the quantity and quality of the retrieved oocytes [28,54,63], which could be associated with impaired fertility and adverse pregnancy out…”
BackgroundObstetrical and neonatal outcomes of pregnancies complicated by endometriosis
Shmueli, A., Salman, L., Hiersch, L., Ashwal, E., Hadar, E., Wiznitzer, A., Yogev, Y., & Aviram, A. (2017) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.1080/14767058.2017.1393513 · Cited by 29
“Other neonatal complications were observed in several studies, including low birthweight, prematurity and stillbirth [16], however, these were not observed in our cohort.”
ResultSalmeri, N., Piani, L. L., Cavoretto, P. I., Somigliana, E., Viganò, P., & Candiani, M. (2023) · Scientific Reports · doi:10.1038/s41598-023-35236-y · Cited by 29
Salmeri, N., Farina, A., Candiani, M., Dolci, C., Bonavina, G., Poziello, C., Viganò, P., & Cavoretto, P. I. (2022) · Diagnostics · doi:10.3390/diagnostics12051024 · Cited by 30
Palomba, S., Santagni, S., Gibbins, K. J., Sala, G. B. L., & Silver, R. M. (2016) · Reproductive BioMedicine Online · doi:10.1016/j.rbmo.2016.08.007 · Cited by 32
The mid-secretory endometrial transcriptomic landscape in endometriosis: a meta-analysis
Vargas, E., García-Moreno, E., Aghajanova, L., Salumets, A., Horcajadas, J. A., Esteban, F. J., & Altmäe, S. (2022) · Human Reproduction Open · doi:10.1093/hropen/hoac016 · Cited by 30
“…involving inflammation, immune modulation, aberrant angiogenesis, oxidative stress, extracellular matrix remodelling, genetic and epigenetic changes could impact endometrial receptivity and implantation process in women with endometriosis (Gupta et al., 2008; Kokcu, 2013; Vigano et al., 2015).”
BackgroundRisk of miscarriage in women with endometriosis: insights from in vitro fertilization cycles
Leonardi, M., Papaleo, E., Reschini, M., Pagliardini, L., Benaglia, L., Candotti, G., Viganò, P., Quaranta, L., Munaretto, M., Candiani, M., et al. (2016) · Fertility and Sterility · doi:10.1016/j.fertnstert.2016.03.047 · Cited by 24
“Recently, interest on this argument has re-flourished (8,9) but, to date, definite conclusions cannot be drawn because the designs of the available studies are generally weak and results inevitably exposed to confounders (Table 1) (10-16).”
BackgroundWang, H., Tsai, C.-L., Chang, P.-Y., Chao, A., Wu, R., Chen, S., Wang, C., Yen, C., Lee, Y., & Wang, T. (2018) · PLoS ONE · doi:10.1371/journal.pone.0190573 · Cited by 22
Carneiro, M. M., Costa, L. M. P., & Ávila, I. D. (2017) · JBRA Assisted Reproduction · doi:10.5935/1518-0557.20170027 · Cited by 21
“…addition, some studies suggest that the presence of endometriosis per se may adversely affect pregnancy and neonatal outcomes (Brosens et al., 2012; Vigano et al., 2015; Jacques et al., 2016), while a recent systematic review stated that complications of endometriosis during pregnancy were rare…”
BackgroundKim, S.-G., Seo, H.-G., & Kim, Y. (2017) · Obstetrics & Gynecology Science · doi:10.5468/ogs.2017.60.3.283 · Cited by 21
Vercellini, P., Viganò, P., Frattaruolo, M. P., Borghi, A., & Somigliana, E. (2018) · Human Reproduction · doi:10.1093/humrep/dey104 · Cited by 20
“In any case, the association seems to be with deep endometriosis in general and not specifically with colorectal endometriosis (Vigano et al., 2015; Leone Roberti Maggiore et al., 2017; Zullo et al., 2017).”
BackgroundGuo, H., Gao, H., Li, J., Cong, Y., Chen, Q., Wang, Y., Zhu, Q., Lyu, Q., Wu, L., Chai, W., et al. (2020) · Annals of Translational Medicine · doi:10.21037/atm.2020.02.15 · Cited by 19
“The expansion of results from most previous studies is limited by the methodology, sample size and accurate diagnosis (28,29).”
ResultGebremedhin, A. T., Mitter, V. R., Duko, B., Tessema, G. A., & Pereira, G. F. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-07002-y · Cited by 19
“MAR treatment itself has shown to be a risk factor for adverse pregnancy outcomes, with mixed results for women with endometriosis [47].”
BackgroundResultMaternal–Fetal Outcomes in Women with Endometriosis and Shared Pathogenic Mechanisms
Frîncu, F., Carp-Velișcu, A., Petca, A., Badiu, D., Brătilă, E., Cîrstoiu, M., & Mehedințu, C. (2021) · Medicina · doi:10.3390/medicina57111258 · Cited by 17
Effects of adenomyosis on obstetric outcomes
Cozzolino, M., Basile, F., & Pontrelli, G. (2019) · Minerva Obstetrics and Gynecology · doi:10.23736/s0026-4784.18.04318-6 · Cited by 17
Adenomyosis: Disease, uterine aging process leading to symptoms, or both?
Πρωτόπαπας, Α., Grimbizis, G., Athanasiou, S., & Loutradis, D. (2020) · PubMed Central · Cited by 17
Endometriosis-related spontaneous hemoperitoneum in the early second trimester: A case report
Huang, L.-Y., Hsu, P.-Y., Chiang, C.-T., Chen, H., & Wu, M. (2021) · Taiwanese Journal of Obstetrics and Gynecology · doi:10.1016/j.tjog.2021.01.032 · Cited by 17
Delivery after Operation for Deeply Infiltrating Endometriosis
Allerstorfer, C., Oppelt, P., Enzelsberger, S., Shamiyeh, A., Schimetta, W., Shebl, O. J., & Mayer, R. B. (2016) · BioMed Research International · doi:10.1155/2016/8271452 · Cited by 17
“Previous studies have shown that deeply infiltrating endometriosis can be associated with a various number of complications during pregnancy and delivery [6].”
BackgroundInfluentialEndometriosis-associated Maternal Pregnancy Complications – Case Report and Literature Review
Petresin, J., Wolf, J., EMİR, S. N., Müller, A., & Boosz, A. S. (2016) · Geburtshilfe und Frauenheilkunde · doi:10.1055/s-0042-101026 · Cited by 15
Jin, Z., Wu, X., Liu, H., & Xu, C. (2020) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2020.8580 · Cited by 15
“Similar to endometriosis, adenomyosis is closely associated with inflammation and angiogenesis (8,9), to which the prostaglandin cascade initiated by cyclooxygenases (COXs) may serve an important role.”
Uterine Artery Pseudoaneurysm in a Pregnant Patient with Retrocervical Endometriosis
Zilberman, A., Eisenberg, V. H., Yoeli, R., Soriano, D., Sivan, E., Golan, G., & Mashiach, R. (2020) · Journal of Minimally Invasive Gynecology · doi:10.1016/j.jmig.2020.03.010 · Cited by 15
Han, X., Gao, X., Wang, F., Shang, C., Liu, Z., & Guo, H. (2023) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.14650 · Cited by 13
Bulun, S. E. (2019) · Elsevier eBooks · doi:10.1016/b978-0-323-47912-7.00025-1 · Cited by 14
Novel TRERF1 mutations in Chinese patients with ovarian endometriosis
Cao, B., Zeng, Y., Wu, F., Liu, J., Shuang, Z., Xu, X., & Guo, J.-B. (2018) · Molecular Medicine Reports · doi:10.3892/mmr.2018.8510 · Cited by 13
Han, Y., Liu, C., Liu, D., Wu, L., & Huang, W. M. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1507252 · Cited by 14
“These factors potentially interfere with folliculogenesis, sperm function, embryo transport, and endometrial receptivity (4, 5).”
Ribot, É., Berbis, J., Hamouda, I., Cohen, D. T., Agostini, A., & Courbière, B. (2021) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2021.102274 · Cited by 12
Spontaneous Hemoperitoneum in Pregnancy and Endometriosis: A New Challenge in a Known Disease
Sharon, N. Z., Shiber, Y., Vaknin, Z., Betser, M., Copel, L., & Maymon, R. (2023) · Obstetrical & Gynecological Survey · doi:10.1097/ogx.0000000000001107 · Cited by 14
“Previous case reports and reviews have reported a favorable outcome when a close follow-up was maintained.(9,11,18,27,28) Repeated assessments of hemoglobin level, vital signs, and sonography are helpful in the early identification and prevention of deterioration.”
ResultYang, B., Wang, L., Wan, X., Li, Y., Yu, X., Qin, Y., Luo, Y., Wang, F., & Huang, O. (2017) · BMC Women s Health · doi:10.1186/s12905-017-0474-z · Cited by 12
“A series of hypotheses that attempt to explain the genesis of adenomyosis has been established [3].”
BackgroundDeep Infiltrating Endometriosis and Adenomyosis: Implications on Pregnancy and Outcome
Gruber, T. M., Ortlieb, L., Henrich, W., & Mechsner, S. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm11010157 · Cited by 11
Impact of Adenomyosis on Infertile Patients—Therapy Options and Reproductive Outcomes
Günther, V., Allahqoli, L., Gitas, G., Maass, N., Tesch, K., Ackermann, J., Rosam, P., Mettler, L., von Otte, S., & Alkatout, İ. (2022) · Biomedicines · doi:10.3390/biomedicines10123245 · Cited by 10
“Furthermore, adenomyosis is associated with higher rates of obstetric complications, such as preterm birth and preterm rupture of the amniotic membranes [19,20].”
BackgroundGruber, T. M., Ortlieb, L., Henrich, W., & Mechsner, S. (2024) · Journal of Clinical Medicine · doi:10.3390/jcm13020414 · Cited by 9
Park, B. Y., Yao, R., Rossi, J., & Lee, A. W. (2023) · Fertility and Sterility · doi:10.1016/j.fertnstert.2023.03.033 · Cited by 8
Edelstein, S., Shachar, I. B., Ben-Amram, H., Biswas, S., & Marcus-Braun, N. (2019) · Infectious Diseases in Obstetrics and Gynecology · doi:10.1155/2019/4149587 · Cited by 8
Hemoperitoneum Following Sexual Intercourse in a Woman with Deep Infiltrating Endometriosis
Buggio, L., Aimi, G., & Vercellini, P. (2016) · Gynecologic and Obstetric Investigation · doi:10.1159/000447262 · Cited by 7
Li, Y., Ge, L., Yang, X., Cui, L., & Chen, Z. (2023) · Frontiers in Medicine · doi:10.3389/fmed.2023.1248274 · Cited by 6
Riemma, G., Cobellis, L., Laganà, A. S., Etrusco, A., Corte, L. D., Torella, M., Vastarella, M. G., Carotenuto, R. M., & FRANCISCIS, P. D. (2025) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.70134 · Cited by 7
“31 This network meta-analysis did not evaluate this issue as only one out of the nine included studies evaluated the co-presence of ade-nomyosis, without providing separate data.”
Adenomyosis and pregnant uterus: An alliance doomed to rupture?
Nohuz, E., Albaut, M., Bayeh, S., Tamburro, S., & Chene, G. (2019) · Journal of Gynecology Obstetrics and Human Reproduction · doi:10.1016/j.jogoh.2019.101632 · Cited by 5
Wang, Y., Hu, Z., Jiang, P., Kong, W., Gong, C., Chen, Y., Xu, L., Yang, Y., & Hu, Z. (2023) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-023-07136-z · Cited by 5
“…pregnancy-related complications (hypertensive disorder complicating pregnancy, PPROM, GDM, postpartum hemorrhage, etc.) was also much higher than that in the low-risk group, which undoubtedly increased the risk of adverse pregnancy outcomes on another level, thus entered a “vicious circle” [7, 27].”
Spontaneous hemoperitoneum in pregnancy due to endometriosis
Kim, T. G., Sudhof, L. S., Liu, F. W., & Shainker, S. A. (2020) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.1177/2284026520942432 · Cited by 5
Labor may mask a symptom of the rupture of ovarian endometrial cyst: a case report
Kino, T., Obata, S., Osanai, N., Hashimoto, A., Okada, Y., Aoki, S., & Miyagi, E. (2018) · Clinical Case Reports · doi:10.1002/ccr3.1554 · Cited by 4
“The clinical symptom of rupture of endometrial cyst is often lower abdominal pain without signs of infection [8].”
BackgroundAgrawala, S., Patil, J., Campbell, S. B., & Woodard, T. L. (2021) · Fertility Research and Practice · doi:10.1186/s40738-021-00097-4 · Cited by 4
Endometriosis and risk factors in pregnancy, labor and delivery: a case-control study
Alboni, C., Cannoletta, M., MOSCA, S., PASINI, S., Farulla, A., & Chiossi, G. (2024) · Minerva Obstetrics and Gynecology · doi:10.23736/s2724-606x.24.05527-1 · Cited by 3
A bélendometriosis miatt végzett műtétek hatása a fertilitásra
Brubel, R., Dobó, N., Csibi, N., Kövesdi, A., Máté, S., Ács, N., Lukovich, P., Murber, Á., & Bokor, A. (2019) · Orvosi Hetilap · doi:10.1556/650.2019.31514 · Cited by 3
Nomograms for predicting adverse obstetric outcome in IVF pregnancy: A preliminary study
Portal, A., Sunyach, C., Loundou, A., Paulmyer‐Lacroix, O., Perrin, J., & Courbière, B. (2021) · Birth · doi:10.1111/birt.12528 · Cited by 3
Gebremedhin, A. T., Mitter, V. R., Duko, B., Tessema, G. A., & Pereira, G. F. (2023) · Research Square · doi:10.21203/rs.3.rs-2462392/v1 · Cited by 3
A narrative review of endometriosis surgery and infertility
Çoban, U., Hatırnaz, Ş., & Kalkan, Ü. (2021) · Gynecology and Pelvic Medicine · doi:10.21037/gpm-20-55 · Cited by 2
“Endometriosis, and particularly DIE, is known risk factor for abnormal placental implantation (11).”
BackgroundFrom Endometriosis to Pregnancy: Which is the “Road-Map”?
Zupi, E., Felice, G. D., Conway, F., Martire, F. G., Exacoustós, C., Centini, G., Patrizi, L., Piccione, E., & Lazzeri, L. (2017) · Journal of Endometriosis and Pelvic Pain Disorders · doi:10.5301/jeppd.5000307 · Cited by 2
“In a review conducted by Viganò et al (90) the prevalence of spontaneous bowel perforations remained unknown.”
BackgroundMethodInfluentialGürgan, T., & Bektaş, G. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-89907-9.00014-4 · Cited by 2
Hemoperitoneu Espontâneo na Gravidez
Gonçalves, D. R., Teixeira, M., Rodrigues, R., & Braga, J. S. (2019) · Acta Médica Portuguesa · doi:10.20344/amp.11169 · Cited by 2
Rare and acute complications of endometriosis in pregnant women
Николаевна, В. Е., Артымук, Н. В., & Zotova, O. A. (2021) · Fundamental and Clinical Medicine · doi:10.23946/2500-0764-2021-6-1-69-76 · Cited by 2
“(2015), показал, что общая распространенность спонтанного гемоперитонеума, связанного с эндометриозом, у беременных составляет около 0,4%, риск его повышен у женщин с эндометриозом в случае зачатия с помощью ЭКО [34].”
Ovsyannikova, M. R., Popov, А. А., Chantieva, T. M., & Shidlovskaya, N. V. (2023) · Russian Bulletin of Obstetrician-Gynecologist · doi:10.17116/rosakush2023230419 · Cited by 1
Impact of adenomyosis on fertility and obstetric outcomes among women in tertiary care center
Hoque, L. F., Begum, F., Apsara, S., & Zinan, A. Z. (2025) · International Journal of Reproduction Contraception Obstetrics and Gynecology · doi:10.18203/2320-1770.ijrcog20250173 · Cited by 1
Harigane, E., Matsushima, T., Watanabe, A., Shinmura, H., Kurashina, R., Shigemi, D., & Suzuki, S. (2025) · Journal of Nippon Medical School · doi:10.1272/jnms.jnms.2025_92-106 · Cited by 1
“Many recent reports have shown a relationship between endometriosis and perinatal complications 1 ― 5 .”
Keß, S., & Germeyer, A. (2023) · Die Gynäkologie · doi:10.1007/s00129-023-05065-1 · Cited by 1
Nkobetchou, M., Cohen, Y., Bonhomme, S., Dallongeville, A., & Azria, É. (2021) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2021.09.005 · Cited by 1
Kinderwunsch und Schwangerschaft bei Endometriose
Shebl, O. J., Ebner, T., & Oppelt, P. (2016) · Gynäkologische Endokrinologie · doi:10.1007/s10304-015-0052-0
L’endométriose, une maladie encore méconnue
Linet, T. (2018) · Vocation Sage-femme · doi:10.1016/j.vsf.2018.05.003
Usefulness of plasma D-dimer levels in detecting ruptured ovarian endometrioma
Kajimura, I., Fujishita, A., Fukushima, A., Matsumoto, K., Yoshitake, T., & Hiraki, K. (2018) · JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY · doi:10.5180/jsgoe.34.1_86
Reproductive disorders and obstetric complications in gynecological diseases
Унанян, А. Л., Is, S., Никонец, А. Д., Аминова, Л. Н., Алимов, В. А., Викторовна, Щ. А., Chushkov, Y. V., & Baburin, D. V. (2018) · GYNECOLOGY · doi:10.26442/2079-5696_2018.2.77-81
Hemoperitoneo postcoital secundario a desgarro mesentérico sin lesión vaginal asociada
Reyna‐Villasmil, E., & Torres-Cepeda, D. (2018) · Avances en Biomédicina
Belaroussi, I., Zanini, A.-S., & Azria, É. (2020) · Elsevier eBooks · doi:10.1016/b978-2-294-76781-4.00017-x
A case of spontaneous bowel perforation in labour secondary to endometriosis
Draper, H., Cunningham, K., Muthukumarasamy, S., & Phillips, K. (2021) · Journal of Obstetrics and Gynaecology · doi:10.1080/01443615.2020.1846167
“It is likely that they are under-reported in the literature and the true prevalence of spontaneous bowel perforation in pregnancy is unknown (Vigano et al. 2015).”
BackgroundDie Uterusruptur – eine lauernde Gefahr
Küpker, W., Agic, A., Diedrich, K., & Felberbaum, R. E. (2022) · Der Gynäkologe · doi:10.1007/s00129-022-04923-8
“Als mögliche Schwangerschafts- und Geburtskomplikationen sind hier das spontane Hämatoperitoneum, Ruptur von Endometriosezysten, Ruptur des Ureters, spontaneDarmperforationenundebendieUterusruptur zu nennen [14].”
BackgroundShi, J., Dai, Y., Zhang, J., Li, X., Jia, S., & Leng, J. (2020) · Research Square · doi:10.21203/rs.3.rs-85435/v1
Pregnancy and Obstetric Outcomes in Endometriosis
Oppelt, P., & Renner, S. P. (2022) · Springer eBooks · doi:10.1007/978-3-030-97236-3_18
Complicated Pelvic Inflammatory Disease
Augustin, G. (2023) · Springer eBooks · doi:10.1007/978-3-031-26021-6_13
Endometriosis-Related Complications in Women Undergoing In Vitro Fertilization
Riemma, G., Vitale, S. G., & Angioni, S. L. (2024) · Springer eBooks · doi:10.1007/978-3-031-50662-8_20
Libretti, A., Nicosia, A., Remorgida, V., & Leo, L. (2025) · Women · doi:10.3390/women5010001
Li, Z., Chen, W., Sun, X., Zhao, X., Hu, J., Ge, L., Wang, W., & Zhang, P. (2025) · Frontiers in Endocrinology · doi:10.3389/fendo.2025.1473923
Miyazaki, Y., Takada, S., Yamazaki, R., Hirabuki, S., & Sasaki, H. (2026) · Cureus · doi:10.7759/cureus.101871
“However, several studies have suggested an association between adhesions and ovarian endometrioma rupture [1,3,5].”
Uterine rupture during labor in a patient with endometriosis: A case report
Häusler, J., Studer, C., Bütikofer, K., & Stevanovic, N. (2026) · Case Reports in Women s Health · doi:10.1016/j.crwh.2026.e00789
Koroneos, Z., Cao, M., Mooney, S. S., Tyson, K., & Holdsworth‐Carson, S. J. (2026) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2026.115094 · Cited by 1
Metadata
- Authors
- Vigano, P., Corti, L., & Berlanda, N.
- Affiliations
- IRCCS Ospedale San Raffaele (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2015-10
- Volume
- 104
- Issue
- 4
- Pages
- 802-812
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W2149590430
- Cited by
- 103
- References
- 85
- Citations by year
- 2026: 5 · 2025: 6 · 2024: 3 · 2023: 15 · 2022: 7 · 2021: 14 · 2020: 10 · 2019: 8 · 2018: 11 · 2017: 12 · 2016: 11 · 2015: 1
- FWCI
- 1.77
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- INFM-OAR (INFN Catania) (submittedVersion, other-oa)
- Zenodo (CERN European Organization for Nuclear Research) (other-oa)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Endometriosis Research and Treatment
- Health Sciences › Medicine › Obstetrics and Gynecology › Ectopic Pregnancy Diagnosis and Management
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Maternal and fetal healthcare
- Keywords
- endometriosis, adenomyosis, pregnancy complications, spontaneous hemoperitoneum, uterine rupture, intestinal perforation, miscarriage, gestational diabetes mellitus, preeclampsia, preterm birth, placenta previa, placental abruption, cesarean section, neonatal outcomes, postpartum complications
- MeSH terms
- Endometriosis, Female, Hemoperitoneum, Humans, Infant, Newborn, Infertility, Ovarian Diseases, Peritoneal Diseases, Pregnancy, Pregnancy Complications, Puerperal Disorders, Postpartum Period, Adenomyosis
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
