The DOI matches its Crossref record; 63 of the 63 references it cites were found in a registry or an index.
Oocyte vitrification for fertility preservation for both medical and nonmedical reasons
Open accessAbstract
Growing evidence of successful outcomes achieved with the oocyte vitrification technique has greatly contributed to its application in the field of fertility preservation (FP). The population that can benefit from FP includes women at a risk of losing their ovarian function because of either iatrogenic causes or natural depletion of their ovarian reserve. Therefore, oncological patients and healthy women who wish to delay motherhood for various reasons-elective FP-are currently being offered this option. Satisfactory oocyte survival rates and clinical outcomes, including cumulative live birth rates, have been reported in recent years. These studies show that age at oocyte retrieval strongly affects reproductive prognosis after FP. Therefore, elective FP patients should be encouraged to decide before they reach the age of 35 years to significantly increase their chances of success. The effect of age has also been observed in patients with cancer and women diagnosed with endometriosis. The reproductive outcome after FP is worse in patients with cancer, but a direct association between the disease and reproductive outcome is yet to be proven. Young patients (≤35 years) with endometriosis who have undergone cystectomy before oocyte retrieval for FP have worse outcomes than nonoperated women in age-matched groups. In addition, the number of oocytes used per patient is closely related to success in all populations, with considerable improvement in the result with the addition of a few oocytes, especially in healthy young patients.
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“In individuals with threats to ovarian reserve such as oncological patients and those with endometriosis, cumulative live birth rate after oocyte cryopreservation is associated with the number of vitrified oocytes.612”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [612]
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“In general, 10 to 20 oocytes are needed for one live birth in non-TS individuals less than 35 years old.612”
From Clinical practice guidelines for the care of girls and women with Turner syndrome. (2024) · cites this paper as [612]
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Citations
Cites
PREGNANCY AFTER HUMAN OOCYTE CRYOPRESERVATION
Chen, C. (1986) · The Lancet · doi:10.1016/s0140-6736(86)90989-x · Cited by 1,011
Mature oocyte cryopreservation: a guideline
(2013) · Fertility and Sterility · doi:10.1016/j.fertnstert.2012.09.028 · Cited by 928
Highly efficient vitrification for cryopreservation of human oocytes and embryos: The Cryotop method
Kuwayama, M. (2006) · Theriogenology · doi:10.1016/j.theriogenology.2006.09.014 · Cited by 859
Rienzi, L. F., Gracia, C. R., Maggiulli, R., LaBarbera, A. R., Kaser, D. J., Ubaldi, F. M., Vanderpoel, S., & Racowsky, C. (2016) · Human Reproduction Update · doi:10.1093/humupd/dmw038 · Cited by 737
Cobo, A., Meseguer, M., Remohi, J. A., & Pellicer, A. (2010) · Human Reproduction · doi:10.1093/humrep/deq146 · Cited by 557
Self-citationBirth following vitrification of a small number of human oocytes: Case Report
Kuleshova, L. L., Gianaroli, L., Magli, M. C., Ferraretti, A. P., & Trounson, A. (1999) · Human Reproduction · doi:10.1093/humrep/14.12.3077 · Cited by 556
Oocyte vitrification as an efficient option for elective fertility preservation
Cobo, A. C., García-Velasco, J. A., Coello, A., Domingo, J., Pellicer, A., & Remohi, J. A. (2015) · Fertility and Sterility · doi:10.1016/j.fertnstert.2015.11.027 · Cited by 538
Self-citationOver 900 oocyte cryopreservation babies born with no apparent increase in congenital anomalies
Noyes, N., Porcu, E., & Borini, A. (2009) · Reproductive BioMedicine Online · doi:10.1016/s1472-6483(10)60025-9 · Cited by 501
Cobo, A. C., & Díaz‐García, C. (2011) · Fertility and Sterility · doi:10.1016/j.fertnstert.2011.06.030 · Cited by 411
Self-citationNiederberger, C., Pellicer, A., Cohen, J., Gardner, D. K., Palermo, G. D., O’Neill, C. L., Chow, S., Rosenwaks, Z., Cobo, A. C., Swain, J. E., et al. (2018) · Fertility and Sterility · doi:10.1016/j.fertnstert.2018.06.005 · Cited by 411
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Mossetti, L., Herrero, I. H., Juliá, M. G., Navarro‐Gomezlechon, A., Pacheco-Rendón, R. M., Rivera‐Egea, R., & Garrido-Puchalt, N. (2024) · Cells · doi:10.3390/cells13221836 · Cited by 1
Aspects on Social Egg Freezing – Current State in Bulgaria
Dyulgerova-Nikolova, D., Antonova, I., Valkova, L., Timeva, T., Yunakova, M., & Milachich, T. (2024) · Acta Medica Bulgarica · doi:10.2478/amb-2024-0072 · Cited by 1
Artificial reproductive technologies (ART), a reproductive physician’s standpoint
Guérin, J.-F. (2025) · Ethics Medicine and Public Health · doi:10.1016/j.jemep.2025.101062 · Cited by 1
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Massarotti, C., Selmi, C., & Marca, A. L. (2025) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-025-03554-x · Cited by 1
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Boumerdassi, Y., Decanter, C., Labrosse, J., Grynberg, M., & Sifer, C. (2023) · Elsevier eBooks · doi:10.1016/b978-2-294-78134-6.00033-4
To freeze or not to freeze for elective fertility preservation
García-Velasco, J. A. (2022) · Fertility and Sterility · doi:10.1016/j.fertnstert.2022.04.032
Self-citationInnovations for Optimizing Fertility and Ovarian Functionality in Female Cancer Patients
Leonel, E. C. R. (2022) · Medical Research Archives · doi:10.18103/mra.v10i10.3265
Castravet, I., Barry, F., Gala, A., Ferrières-Hoa, A., Loup, V., Mullet, T., Brunet, C., Brouillet, S., & Hamamah, S. (2023) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2023.01.009
Planned Fertility Preservation
Vyas, N., & Goldschlag, D. E. (2023) · Contemporary Endocrinology · doi:10.1007/978-3-031-19443-6_33
Germeyer, A., & Nawroth, F. (2023) · Die Dermatologie · doi:10.1007/s00105-023-05171-0
Takeuchi, H., Maezawa, T., Hagiwara, K., Horage, Y., Hanada, T., Huang, H., Sakamoto, M., Nishioka, M., Takayama, E., Terada, K., et al. (2023) · Reproductive Medicine and Biology · doi:10.1002/rmb2.12534
Murillo, E. O., Peña, C. J., Hidalgo, J.-J., Monllor-Tormos, A., Zolfaroli, I., Vila, M. J., Sánchez-Serrano, M., Pellicer, A., & Cano, A. (2023) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-023-02949-y
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Namath, A. G., Jahandideh, S. S., Devine, K., Kallen, C. B., & O’Brien, J. E. (2023) · Journal of Assisted Reproduction and Genetics · doi:10.1007/s10815-023-02962-1
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Baston-Büst, D. M., Bielfeld, A. P., Scheliga, I., Edimiris, P., Bender-Liebenthron, J., & Krüssel, J.-S. (2023) · Die Gynäkologie · doi:10.1007/s00129-023-05149-y
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Abderrahim, S. B., Turki, E., Zemni, Z., & Zemni, M. (2023) · Gynécologie Obstétrique Fertilité & Sénologie · doi:10.1016/j.gofs.2023.10.008
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Baston-Büst, D. M., Bielfeld, A. P., Scheliga, I., Edimiris, P., Bender-Liebenthron, J., & Krüssel, J.-S. (2023) · TumorDiagnostik & Therapie · doi:10.1055/a-2128-7608
Progress and challenges in ovum retrieval surgery
Gong, Z., You, X., Li, H., & Xie, C. H. (2024) · Asian Journal of Surgery · doi:10.1016/j.asjsur.2023.12.193
Fertility Preservation Strategies in Cancer Patients: A Comprehensive Review
Razik, M., Bator, P., Rozwadowska, P., Ramian, J., Rybak, J., Magiera, B., Magiera, K., & Razik, W. (2024) · Journal of Education Health and Sport · doi:10.12775/jehs.2024.61.008
Conceptos de criobiología y fisiología ovárica en la preservación de la fertilidad
Méndez, M., Cívico, Y., & Casals, G. (2024) · Clínica e Investigación en Ginecología y Obstetricia · doi:10.1016/j.gine.2024.100948
Yerushalmi, G., Avraham, S., Kedem, A., Youngster, M., Barkat, J., Baruchin, O., Gat, I., Yaakov, O., Gidoni, Y., & Hourvitz, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-65059-4
Handling and Assessing of Human Oocytes and Blastocysts After Vitrification and Warming
Conversa, L., Cobo, A. C., & Meseguer, M. (2024) · Springer eBooks · doi:10.1007/978-3-031-58214-1_29
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Sparks, A. E. (2024) · Springer eBooks · doi:10.1007/978-3-031-58214-1_39
Barral, Y., Vidal, M., Peralta, S., & Magnano, L. (2024) · Clínica e Investigación en Ginecología y Obstetricia · doi:10.1016/j.gine.2024.101005
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Хасанов, Н. Б., Yuburova, S. M., & Alybaeva, T. K. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.99.57.303
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MUKHAMBETZHANOV, S. T., & Mussina, A. A. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.34.26.017
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Li, J. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.90.85.004
Redina, A. V. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.41.16.007
Avilov, Y. D., & Kharlanov, A. S. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.30.71.302
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Kharlanov, A. S., Evans, J. N., & Novikov, M. M. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.38.37.297
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Левонович, В. С., Gasparov, A. S., & Феликсович, Д. М. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.10.45.011
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Romanovich, V. A. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.18.24.001
Vedyshev, I. I. (2024) · Practice Oriented Science: UAE – Russia – India · doi:10.34660/inf.2023.10.17.299
Petrushko, M. P., Piniaiev, V. I., & Yurchuk, T. O. (2025) · Reports of Morphology · doi:10.31393/morphology-journal-2025-31(1)-01
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Gigolaeva, L. A., Dubenkina, E. A., Semkina, E. V., Ushkova, K. D., Mazka, S. V., Zhadanova, P. Y., Imamova, Z. A., Barmenkova, P. M., Zhiltsova, N. D., Amayeva, D. S., et al. (2025) · Obstetrics Gynecology and Reproduction · doi:10.17749/2313-7347/ob.gyn.rep.2025.683
Serdarogullari, M., Atayurt, Z., Raad, G., Karakaya, H., Yilancilar, Y., Ammar, O., Yarkıner, Z., Yüksel, B., Meseguer, M., & Liperis, G. (2026) · Reproduction and Fertility · doi:10.1530/raf-26-0003
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Salhoov, H., Yogev, M., Azulay, R., Shinan, E., Bentov, Y., Godin, M., Esh‐Broder, E., Hizkiyahu, R., Lazarovits, C. A., & Klement, A. H. (2026) · International Journal of Gynecology & Obstetrics · doi:10.1002/ijgo.71115
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Metadata
- Authors
- Cobo, A., García-Velasco, J. A., Remohí, J., & Pellicer, A.
- Affiliations
- IVIRMA Global (ES)
- Universidad Rey Juan Carlos (ES)
- Corresponding author
- Cobo, Ana
- Venue
- Fertility and Sterility
- Publisher
- Elsevier BV
- Published
- 2021-05
- Volume
- 115
- Issue
- 5
- Pages
- 1091-1101
- ISSN
- 0015-0282 (ISSN-L)
- OpenAlex
- W3159958283
- Cited by
- 165
- References
- 63
- Citations by year
- 2026: 24 · 2025: 25 · 2024: 53 · 2023: 39 · 2022: 19 · 2021: 5
- FWCI
- 5.17
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Fertility and Sterility (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Biology and Fertility
- Health Sciences › Medicine › Reproductive Medicine › Reproductive Health and Technologies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Reproductive biology and impacts on aquatic species
- Keywords
- oocyte vitrification, fertility preservation, elective fertility preservation, ovarian reserve depletion, cancer patients, endometriosis, oocyte number, live birth rate, ovarian preservation
- MeSH terms
- Adult, Female, Humans, Medical Oncology, Oocytes, Cryopreservation, Elective Surgical Procedures, Reproductive Medicine, Vitrification, Fertility Preservation
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