Free radical-scavenging phytochemicals of hot water extracts of Acacia confusa leaves detected by an on-line screening method
Abstract
Acacia confusa Merr. (Leguminosae), a species native to Taiwan, is widely distributed on the hills and lowlands of Taiwan, and has been traditionally used as a medicine. In this study, phytochemicals and antioxidant activities of hot water extracts from A. confusa leaves were investigated for the first time. Among all the fractions from hot water extracts of leaves, the EtOAc-soluble fraction exhibits the best DPPH radical-scavenging activity, superoxide radical-scavenging activity, and reducing power. In addition, a rapid screening method, on-line RP-HPLC-DPPH system, for individual antioxidants in the EtOAc-soluble fraction was developed. Furthermore, following solid phase extraction (SPE) and reverse-phase high-performance liquid chromatography 12 pure phenolic compounds, including five major compounds (gallic acid, (+)-catechin, (-)-epicatechin, myricetin 3-glucopyranoside, and myricetin 3-rhamnopyranoside) were detected using the developed screening method. These results demonstrated that hot water extracts of A. confusa leaves have excellent antioxidant activities and thus have great potential as a source for natural health products.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Some studies have already reported the antioxidant capacity of olive and mimosa leaf extracts.
“Some studies have already reported the antioxidant capacity of olive [17,18,22] and mimosa leaf [8,71] extracts.”
From Comparison of Techniques and Solvents on the Antimicrobial and Antioxidant Potential of Extracts from Acacia dealbata and Olea europaea (2020) · cites this paper as [71]
Cites
Oyaizu, M. (1986) · The Japanese Journal of Nutrition and Dietetics · doi:10.5264/eiyogakuzashi.44.307 · Cited by 7,733 · see citing works
Tannins and Human Health: A Review
Chung, K.-T., Wong, T. Y., Wei, C.-I., Huang, Y.-W., & Lin, Y. (1998) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408699891274273 · Cited by 1,996 · see citing works
Quettier-Deleu, C., Gressier, B., Vasseur, J., Dine, T., Brunet, C., Luyckx, M., CAZIN, M., Cazin, J. C., Bailleul, F., & Trotin, F. (2000) · Journal of Ethnopharmacology · doi:10.1016/s0378-8741(00)00196-3 · Cited by 1,203 · see citing works
Yamaguchi, T., Takamura, H., Matoba, T., & Terao, J. (1998) · Bioscience Biotechnology and Biochemistry · doi:10.1271/bbb.62.1201 · Cited by 1,107 · see citing works
The Mechanism of Antioxidant Action in Vitro
Gordon, M. H. (1990) · Springer eBooks · doi:10.1007/978-94-009-0753-9_1 · Cited by 971 · see citing works
von Gadow, A., Joubert, E., & Hansmann, C. F. (1997) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf960281n · Cited by 583 · see citing works
Antioxidant Activity of Extracts from Acacia confusa Bark and Heartwood
Chang, S., Wu, J., Wang, S., Kang, P.-L., Yang, N., & Shyur, L. (2001) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0100907 · Cited by 490 · see citing works
Self-citationMalonylated flavonol glycosides from the petals of Clitoria ternatea
Kazuma, K. (2002) · Phytochemistry · doi:10.1016/s0031-9422(02)00486-7 · Cited by 445 · see citing works
Tanaka, M., Chiu, W. K., Nagashima, Y., & Taguchi, T. (1988) · NIPPON SUISAN GAKKAISHI · doi:10.2331/suisan.54.1409 · Cited by 389 · see citing works
ANTIOXIDANT PROPERTIES OF POLYPHENOLS EXTRACTED FROM GREEN AND BLACK TEAS
CHEN, C., & Ho, C. (1995) · Journal of Food Lipids · doi:10.1111/j.1745-4522.1995.tb00028.x · Cited by 389 · see citing works
Shon, M.-Y., Choi, S.-D., Kahng, G. G., et al. (2004) · Food and Chemical Toxicology · doi:10.1016/j.fct.2003.12.002 · Cited by 274 · see citing works
2,2-Diphenyl-1-picrylhydrazyl Radical-Scavenging Active Components from Polygonum multiflorum Thunb.
Chen, Y., Wang, M., Rosen, R. T., et al. (1999) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf990092f · Cited by 263 · see citing works
An On-Line HPLC Method for Detection of Radical Scavenging Compounds in Complex Mixtures
Koleva, I. I., Niederländer, H. A. G., & van Beek, T. A. (2000) · Analytical Chemistry · doi:10.1021/ac9912451 · Cited by 252 · see citing works
Antioxidant activities of ethanolic extracts from the twigs of Cinnamomum osmophloeum
Chua, M.-T., Tung, Y., & Chang, S. (2007) · Bioresource Technology · doi:10.1016/j.biortech.2007.03.020 · Cited by 222 · see citing works
Self-citationAntioxidant activities of natural phenolic compounds from Acacia confusa bark
Tung, Y., Wu, J., Kuo, Y., & Chang, S. (2006) · Bioresource Technology · doi:10.1016/j.biortech.2006.04.017 · Cited by 151 · see citing works
Self-citationAntimutagenicity of hydrolyzable tannins from Terminalia chebula in Salmonella typhimurium
Kaur, S., Grover, I. S., Singh, M., et al. (1998) · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · doi:10.1016/s1383-5718(98)00130-2 · Cited by 99 · see citing works
Khallouki, F., Haubner, R., Hull, W. E., et al. (2006) · Food and Chemical Toxicology · doi:10.1016/j.fct.2006.09.011 · Cited by 97 · see citing works
Novel Flavonol Glycoside, 7-O-Methyl Mearnsitrin, from Sageretia theezans and Its Antioxidant Effect
Chung, S., Kim, Y., Takaya, Y., et al. (2004) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf049526j · Cited by 93 · see citing works
Wu, J., Huang, C., Tung, Y., et al. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf072314c · Cited by 92 · see citing works
Self-citationPhenolic Antioxidants from the Heartwood of Acacia confusa
Wu, J., Tung, Y., Wang, S., Shyur, L., Kuo, Y., & Chang, S. (2005) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf050550m · Cited by 90 · see citing works
Self-citationAntioxidant activities and phytochemical characteristics of extracts from Acacia confusa bark
Tung, Y., Wu, J., Huang, C., Kuo, Y., & Chang, S. (2008) · Bioresource Technology · doi:10.1016/j.biortech.2008.01.001 · Cited by 71 · see citing works
Self-citationThree New Flavonol Galloylglycosides from Leaves of Acacia confusa
Lee, T., Qiu, F., Waller, G. R., et al. (2000) · Journal of Natural Products · doi:10.1021/np990482w · Cited by 53 · see citing works
Antioxidant galloylated flavonol glycosides from Calliandra haematocephala
Moharram, F. A.-E., Marzouk, M., Ibrahim, M. T., et al. (2006) · Natural Product Research · doi:10.1080/14786410500378494 · Cited by 50 · see citing works
Flavonol Glycosides in Two Diospyros Plants and Their Radical Scavenging Activity
Tanaka, T., Furusawa, M., Ito, T., et al. (2003) · Heterocycles · doi:10.3987/com-03-9882 · Cited by 13 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Natural and synthetic antioxidants: An updated overview
Augustyniak, A., Bartosz, G., Čipak, A., Duburs, G., Horáková, L., Łuczaj, W., Majekova, M., Odysseos, A. D., Rackova, L., Skrzydlewska, E., et al. (2010) · Free Radical Research · doi:10.3109/10715762.2010.508495 · Cited by 319 · see citing works
Borges, A., José, H., Homem, V., & Simões, M. (2020) · Antibiotics · doi:10.3390/antibiotics9020048 · Cited by 184 · see citing works
“Some studies have already reported the antioxidant capacity of olive [17,18,22] and mimosa leaf [8,71] extracts.”
BackgroundPhytochemistry, Ethnomedicine, and Pharmacology of Acacia
(2018) · Studies in Natural Products Chemistry · doi:10.1016/b978-0-444-64057-4.00009-0 · Cited by 52 · see citing works
- Authors
- Tung, Y.-T., Wu, J.-H., Hsieh, C.-Y., Chen, P.-S., & Chang, S.-T.
- Affiliations
- National Taiwan University (TW)
- National Chung Hsing University (TW)
- Corresponding author
- Chang, Shang-Tzen
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2009-08
- Volume
- 115
- Issue
- 3
- Pages
- 1019-1024
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W2118658402
- Cited by
- 62
- References
- 24
- Citations by year
- 2026: 1 · 2023: 2 · 2022: 4 · 2021: 4 · 2020: 1 · 2019: 3 · 2018: 3 · 2017: 1 · 2016: 2 · 2015: 6 · 2014: 9 · 2013: 5 · 2012: 5
- FWCI
- 4.53
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Food Chemistry (publishedVersion)
- Topics
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Phytochemistry and Biological Activities
- Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
- Keywords
- Acacia confusa, leaf extract, antioxidant activity, free radical scavenging, phenolic compounds, gallic acid, catechins, myricetin glycosides, hot water extraction, natural health products, traditional medicine
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review