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The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.

In vitro antioxidant activity of Kyoho grape extracts in DPPH and ABTS assays: Estimation methods for EC50 using advanced statistical programs

Sridhar, Kandi, Charles, Albert Linton·2019·Food Chemistry

Abstract

The antioxidant capacities of Kyoho skin, seed, and flesh extracts were determined using DPPH and ABTS assays and a suitable statistical program was tested for the prediction of EC50 values of Kyoho skin, seed, and flesh extracts obtained by DPPH and ABTS assays. Statistical programs: OriginPro® version 8, GraphPad Prism® version 7, GraphPad Prism® version 7 five-parameter (5P) logistic model, SigmaPlot® version 14.0, Microsoft Excel® version 2016, interpolation log, and direct interpolation methods were employed to estimate the EC50 values. Linear regression and direct interpolation results showed deviations for non-linear models in the prediction of EC50 values of grape extracts. The correlation results of grape flesh extracts demonstrated a positive correlation (r = ≥ 0.95) between EC50 values of antioxidant assays. Therefore, non-linear methods were appropriate for EC50 calculations. These findings have significant implications for selecting an efficient statistical tool to calculate EC50 values for DPPH and ABTS assays.

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Show all 23 references

Research works printed but not linked: 6

  1. Chen, 2014, Grape Production in Taiwan, Taiwan Society for Horticultural Science, 60, 185
  2. Gadagkar, 2015, Computational tools for fitting the Hill equation to dose–response curves, Journal of Pharmacological and Toxicological Methods, 71, 68, 10.1016/j.vascn.2014.08.006 · doi:10.1016/j.vascn.2014.08.006
  3. Li, 2014, A comparison of different estimation methods for fungicide EC50 and EC95 values, Journal of Phytopathology, 163, 239, 10.1111/jph.12312 · doi:10.1111/jph.12312
  4. Mandić, 2009, Antioxidant activity of white grape seed extracts on DPPH radicals, Acta Periodica Technologica, 40, 53, 10.2298/APT0940053M · doi:10.2298/apt0940053m
  5. Villaño, 2006, Influence of enological practices on the antioxidant activity of wines, Food Chemistry, 95, 394, 10.1016/j.foodchem.2005.01.005 · doi:10.1016/j.foodchem.2005.01.005
  6. Youssef, 2006, Study on grape seeds extraction and optimization: An approach, Journal of Applied Sciences, 6, 2944, 10.3923/jas.2006.2944.2947 · doi:10.3923/jas.2006.2944.2947

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Metadata

Authors
Sridhar, K., & Charles, A. L.
Venue
Food Chemistry
Publisher
Elsevier BV
Published
2019-03
Volume
275
Pages
41-49
ISSN
0308-8146 (ISSN-L)
OpenAlex
W2889940709
Cited by
409
References
23
FWCI
16.68
Type
journal article
Language
en
Open access
closed
Licence
  • www.elsevier.com/tdm/userlicense/1.0/ (tdm)
  • www.elsevier.com/legal/tdmrep-license (tdm)

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CoChat. (2026). Citation check: In vitro antioxidant activity of Kyoho grape extracts in DPPH and ABTS assays: Estimation methods for EC50 using advanced statistical programs. https://app.cochat.ai/papers/10.1016/j.foodchem.2018.09.040
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Sridhar, K., & Charles, A. L. (2019). In vitro antioxidant activity of Kyoho grape extracts in DPPH and ABTS assays: Estimation methods for EC50 using advanced statistical programs. Food Chemistry. https://doi.org/10.1016/j.foodchem.2018.09.040

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