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Simultaneous extraction and separation of bioactive compounds from apple pomace using pressurized liquids coupled on-line with solid-phase extraction
Open accessAbstract
The objective of this work was the development of an on-line extraction/fractionation method based on the coupling of pressurized liquid extraction and solid-phase extraction for the separation of phenolic compounds from apple pomace. Several variables of the process were evaluated, including the amount of water of the first stage (0-120 mL), temperature (60-80 °C), solid-phase extraction adsorbent (Sepra, Isolute, Strata X and Oasis) and activation/elution solvent (methanol and ethanol). The best results were observed with the adsorbent Sepra. The temperature had a small effect on recovery, but significant differences were observed for phlorizin and a quercetin derivative. Results indicate that ethanol can be used to replace methanol as an activation, extraction/elution solvent. While using mostly green solvents (water, ethanol, and a small amount of methanol that could be reused), the developed method produced higher or similar yields of acids (2.85 ± 0.19 mg/g) and flavonoids (0.97 ± 0.11 mg/g) than conventional methods.
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“In addition, pressurized liquid extraction, which involves the use of high pres-sure and temperature to enhance extraction efficiency, has been successfully combined with solid phase extraction to concurrently extract and isolate phenolic compounds from apple pomace [73].”
From Valorization of Food Waste to Produce Value-Added Products Based on Its Bioactive Compounds (2023) · cites this paper as [73]
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Metadata
- Authors
- da Silva, L. C., Souza, M. C., Sumere, B. R., Silva, L. G. S., da Cunha, D. T., Barbero, G. F., Bezerra, R. M. N., & Rostagno, M. A.
- Affiliations
- Universidade Estadual de Campinas (UNICAMP) (BR)
- Universidad de Cádiz (ES)
- Venue
- Food Chemistry
- Publisher
- Elsevier BV
- Published
- 2020-07
- Volume
- 318
- Pages
- 126450
- ISSN
- 0308-8146 (ISSN-L)
- OpenAlex
- W3007892079
- Semantic Scholar
- 30c7d2f984b58211bfce918d20845cd9b690ccd5
- Cited by
- 82
- References
- 45
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 16 · 2023: 13 · 2022: 24 · 2021: 15 · 2020: 5
- FWCI
- 7.70
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Food Chemistry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (001, 88887.310558/2018-00)
- Conselho Nacional de Desenvolvimento Científico e Tecnológico (303568/2016-0)
- Fundação de Amparo à Pesquisa do Estado de São Paulo (2019/24537-0, 2018/17089-8, 2016/19930-6, 2018/14582-5, 2013/043044)
- Topics
- Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
- Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Keywords
- apple pomace, accelerated solvent extraction, solid-phase extraction, phenolic compounds, flavonoids, phloridzin, quercetin derivatives, green solvents, ethanol elution, adsorbent comparison, bioactive compounds
- MeSH terms
- Chromatography, High Pressure Liquid, Flavonoids, Gallic Acid, Phenols, Phlorhizin, Plant Extracts, Pressure, Quercetin, Solvents, Temperature, Malus, Solid Phase Extraction, Tandem Mass Spectrometry
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