Recent advances in extraction of nutraceuticals from plants
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SFE uses fluids in supercritical conditions; CO2 is the most used solvent due to nontoxicity, safety, and low cost; SC-CO2 extracts nonpolar or low polarity compounds, but polar compounds can be extracted by adding polar co-solvents such as ethanol or methanol.
“SFE is based on the principle of extraction with fluids in their supercritical conditions, temperature, and pressure are raised above their critical point with characteristics of both liquids and gases [33].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [27]
Modern extraction methods (SFE, SWE, UAE, MAE) have advantages over conventional methods, including reduced solvent, shorter time, lower temperature, better selectivity, and avoidance of byproducts.
“Alternatives, often classified as green methods, showed several benefits over the conventional methods, including reduced amounts of used solvent, shorter extraction time, and performance at lower temperature. These methods have better selectivity for the isolation of desired compounds, while the formation of byproducts and unwanted reactions during the extraction are avoided [26,27].”
From Overview on the Application of Modern Methods for the Extraction of Bioactive Compounds from Marine Macroalgae (2018) · cites this paper as [27]
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- Authors
- Wang, L., & Weller, C. L.
- Affiliations
- University of Nebraska–Lincoln (US)
- Corresponding author
- Wang, Lijun
- ORCID
- Weller, Curtis L.
- Venue
- Trends in Food Science & Technology
- Publisher
- Elsevier BV
- Published
- 2006-06
- Volume
- 17
- Issue
- 6
- Pages
- 300-312
- ISSN
- 0924-2244 (ISSN-L)
- OpenAlex
- W2044910245
- Cited by
- 2,046
- References
- 86
- Citations by year
- 2026: 65 · 2025: 105 · 2024: 108 · 2023: 116 · 2022: 146 · 2021: 166 · 2020: 159 · 2019: 156 · 2018: 125 · 2017: 153 · 2016: 117 · 2015: 129 · 2014: 135 · 2013: 108 · 2012: 78
- FWCI
- 36.59
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Trends in Food Science & Technology (publishedVersion)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Agricultural and Biological Research
- Health Sciences › Nursing › Nutrition and Dietetics › Food Science and Nutritional Studies
- Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
- Keywords
- nutraceuticals, plant extracts, extraction methods, ultrasound-assisted extraction, microwave-assisted extraction, supercritical fluid extraction, accelerated solvent extraction, Soxhlet extraction, solvent consumption, extraction yield
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