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Analysis of 22 Y chromosomal STR haplotypes and Y haplogroup distribution in Pathans of Pakistan

Lee, Eun Young, Shin, Kyoung-Jin, Rakha, Allah, Sim, Jeong Eun, Park, Myung Jin, Kim, Na Young, Yang, Woo Ick, Lee, Hwan Young·2014·Forensic Science International: Genetics
DOI 10.1016/j.fsigen.2014.03.004
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Abstract

We analyzed haplotypes for 22 Y chromosomal STRs (Y-STRs), including 17 Yfiler loci (DYS19, DYS385a/b, DYS389I/II, DYS390, DYS391, DYS392, DYS393, DYS437, DY438, DYS439, DYS448, DYS456, DYS458, DYS635 and Y-GATA-H4) and five additional STRs (DYS388, DYS446, DYS447, DYS449 and DYS464), and Y chromosomal haplogroup distribution in 270 unrelated individuals from the Pathans residing in the Federally Administered Tribal Areas and the North-West Frontier Province of Pakistan using in-house multiplex PCR systems. Each Y-STR showed diversities ranging from 0.2506 to 0.8538, and the discriminatory capacity (DC) was 73.7% with 199 observed haplotypes using 17 Yfiler loci. By the addition of 5 Y-STRs to the Yfiler system, the DC was increased to 85.2% while showing 230 observed haplotypes. Among the additional 5 Y-STRs, DYS446, DYS447 and DYS449 were major contributors to enhancing discrimination. In the analysis of molecular variance, the Pathans of this study showed significant differences from other Pathan populations as well as neighboring population sets. In Y-SNP analysis, a total of 12 Y chromosomal haplogroups were observed and the most frequent haplogroup was R1a1a with 49.3% frequency. To obtain insights on the origin of Pathans, the network analysis was performed for the haplogroups G and Q observed from the Pathans and the Jewish population groups including Ashkenazim and Sephardim, but little support for a Jewish origin could be found. In the present study, we report Y-STR…

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Research works printed but not linked: 36

  1. de Knijff, 1997, Chromosome Y microsatellites: population genetic and evolutionary aspects, Int. J. Legal Med., 110, 134, 10.1007/s004140050052 · DOI
  2. Jobling, 1997, The Y chromosome in forensic analysis and paternity testing, Int. J. Legal Med., 110, 118, 10.1007/s004140050050 · DOI
  3. Brookfield, 1995, Human evolution Y-chromosome clues to human ancestry, Curr. Biol., 5, 1114, 10.1016/S0960-9822(95)00224-7 · DOI
  4. Sánchez-Diz, 2008, Population and segregation data on 17 Y-STRs: results of a GEP-ISFG collaborative study, Int. J. Legal Med., 122, 529, 10.1007/s00414-008-0265-z · DOI
  5. Mulero, 2006, Development and validation of the AmpFlSTR Yfiler PCR amplification kit: a male specific, single amplification 17 Y-STR multiplex system, J. Forensic Sci., 51, 64, 10.1111/j.1556-4029.2005.00016.x · DOI
  6. Gross, 2008, Internal validation of the AmpFlSTR Yfiler amplification kit for use in forensic casework, J. Forensic Sci., 53, 125, 10.1111/j.1556-4029.2008.00591.x · DOI
  7. Willuweit, 2007, Y chromosome haplotype reference database (YHRD): update, Forensic Sci. Int. Genet., 1, 83, 10.1016/j.fsigen.2007.01.017 · DOI
  8. Vermeulen, 2009, Improving global and regional resolution of male lineage differentiation by simple single-copy Y-chromosomal short tandem repeat polymorphisms, Forensic Sci. Int. Genet., 3, 205, 10.1016/j.fsigen.2009.01.009 · DOI
  9. Mohyuddin, 2001, Y-chromosomal STR haplotypes in Pakistani populations, Forensic Sci. Int., 118, 141, 10.1016/S0379-0738(01)00382-6 · DOI · Paper page
  10. Ghosh, 2011, Genetic diversity of 17 Y-short tandem repeats in Indian population, Forensic Sci. Int. Genet., 5, 363, 10.1016/j.fsigen.2010.12.007 · DOI
  11. Haber, 2012, Genographic Consortium, Afghanistan's ethnic groups share a Y-chromosomal heritage structured by historical events, PLoS ONE, 7, e34288, 10.1371/journal.pone.0034288 · DOI · Paper page
  12. Lacau, 2011, Y-STR profiling in two Afghanistan populations, Leg. Med., 13, 103, 10.1016/j.legalmed.2010.11.004 · DOI
  13. Achakzai, 2012, Y-chromosomal STR analysis in the Pashtun population of Southern Afghanistan, Forensic Sci. Int. Genet., 6, e103, 10.1016/j.fsigen.2011.10.005 · DOI
  14. Lee, 2007, Haplotypes and mutation analysis of 22 Y-chromosomal STRs in Korean father–son pairs, Int. J. Legal Med., 121, 128, 10.1007/s00414-006-0130-x · DOI
  15. Frank, 2008, Y chromosome STR haplotypes and allele frequencies in a southern Indian male population, J. Forensic Sci., 53, 248, 10.1111/j.1556-4029.2007.00633.x · DOI
  16. Yadav, 2011, Haplotype diversity of 17 Y-chromosomal STRs in Saraswat Brahmin Community of North India, Forensic Sci. Int. Genet., 5, e63, 10.1016/j.fsigen.2010.09.012 · DOI
  17. Roy, 2012, Genetic analysis of 17 Y-chromosomal STRs haplotypes of three ethnic groups residing in West Bengal, India, Forensic Sci. Int. Genet., 6, e5, 10.1016/j.fsigen.2010.11.002 · DOI
  18. Roewer, 2009, A Y-STR database of Iranian and Azerbaijanian minority populations, Forensic Sci. Int. Genet., 4, e53, 10.1016/j.fsigen.2009.05.002 · DOI
  19. Behar, 2004, Contrasting patterns of Y chromosome variation in Ashkenazi Jewish and host non-Jewish European populations, Hum. Genet., 114, 354, 10.1007/s00439-003-1073-7 · DOI
  20. Adams, 2008, The genetic legacy of religious diversity and intolerance: paternal lineages of Christians, Jews, and Muslims in the Iberian Peninsula, Am. J. Hum. Genet., 83, 725, 10.1016/j.ajhg.2008.11.007 · DOI
  21. Bandelt, 1999, Median-joining networks for inferring intraspecific phylogenies, Mol. Biol. Evol., 16, 37, 10.1093/oxfordjournals.molbev.a026036 · DOI · Paper page
  22. Excoffier, 2005, Arlequin (version 3.0): an integrated software package for population genetics data analysis, Evol. Bioinform. Online, 1, 47, 10.1177/117693430500100003 · DOI
  23. Firasat, 2007, Y-chromosomal evidence for a limited Greek contribution to the Pathan population of Pakistan, Eur. J. Hum. Genet., 15, 121, 10.1038/sj.ejhg.5201726 · DOI
  24. Hanson, 2007, An ultra-high discrimination Y chromosome short tandem repeat multiplex DNA typing system, PLoS ONE, 2, e688, 10.1371/journal.pone.0000688 · DOI
  25. Rodig, 2008, Evaluation of haplotype discrimination capacity of 35 Y-chromosomal short tandem repeat loci, Forensic Sci. Int., 174, 182, 10.1016/j.forsciint.2007.04.223 · DOI
  26. Ballantyne, 2010, Mutability of Y-chromosomal microsatellites: rates, characteristics, molecular bases, and forensic implications, Am. J. Hum. Genet., 87, 341, 10.1016/j.ajhg.2010.08.006 · DOI
  27. Ballantyne, 2012, A new future of forensic Y-chromosome analysis: rapidly mutating Y-STRs for differentiating male relatives and paternal lineages, Forensic Sci. Int. Genet., 6, 208, 10.1016/j.fsigen.2011.04.017 · DOI
  28. Butler, 2006, Allele frequencies for 27 Y-STR loci with U.S. Caucasian, African American, and Hispanic samples, Forensic Sci. Int., 156, 250, 10.1016/j.forsciint.2005.02.011 · DOI
  29. Gusmão, 2006, DNA Commission of the International Society of Forensic Genetics (ISFG): an update of the recommendations on the use of Y-STRs in forensic analysis, Forensic Sci. Int., 157, 187, 10.1016/j.forsciint.2005.04.002 · DOI
  30. Jacobs, 2009, Development and evaluation of multiplex Y-STR assays for application in molecular genealogy, Forensic Sci. Int. Genet. Suppl., 2, 57, 10.1016/j.fsigss.2009.08.114 · DOI
  31. Mohyuddin, 2006, Detection of novel Y SNPs provides further insights into Y chromosomal variation in Pakistan, J. Hum. Genet., 51, 375, 10.1007/s10038-005-0357-2 · DOI
  32. Nebel, 2001, Haplogroup-specific deviation from the stepwise mutation model at the microsatellite loci DYS388 and DYS392, Eur. J. Hum. Genet., 9, 22, 10.1038/sj.ejhg.5200577 · DOI
  33. Rakha, 2011, Forensic and genetic characterization of mtDNA from Pathans of Pakistan, Int. J. Legal Med., 125, 841, 10.1007/s00414-010-0540-7 · DOI
  34. Schoske, 2004, High-throughput Y-STR typing of U.S. populations with 27 regions of the Y chromosome using two multiplex PCR assays, Forensic Sci. Int., 139, 107, 10.1016/j.forsciint.2003.10.007 · DOI
  35. Karafet, 2008, New binary polymorphisms reshape and increase resolution of the human Y chromosomal haplogroup tree, Genome Res., 18, 830, 10.1101/gr.7172008 · DOI · Paper page
  36. Park, 2013, Y-SNP miniplexes for East Asian Y-chromosomal haplogroup determination in degraded DNA, Forensic Sci. Int. Genet., 7, 75, 10.1016/j.fsigen.2012.06.014 · DOI

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Metadata

Authors
Lee, E. Y., Shin, K.-J., Rakha, A., Sim, J. E., Park, M. J., Kim, N. Y., Yang, W. I., & Lee, H. Y.
Venue
Forensic Science International: Genetics
Publisher
Elsevier BV
Published
2014-07
Volume
11
Pages
111-116
ISSN
1872-4973
DOI
10.1016/j.fsigen.2014.03.004
Cited by
22
References
1
Language
en
Licence
Funders
  • National Research Foundation of Korea
  • Ministry of Education, Science and Technology (2010-0020631, 2011-0027729)

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CoChat. (2026). Citation check: Analysis of 22 Y chromosomal STR haplotypes and Y haplogroup distribution in Pathans of Pakistan. https://app.cochat.ai/papers/10.1016/j.fsigen.2014.03.004
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Lee, E. Y., Shin, K.-J., Rakha, A., Sim, J. E., Park, M. J., Kim, N. Y., Yang, W. I., & Lee, H. Y. (2014). Analysis of 22 Y chromosomal STR haplotypes and Y haplogroup distribution in Pathans of Pakistan. Forensic Science International: Genetics. https://doi.org/10.1016/j.fsigen.2014.03.004