Cellular senescence: putting the paradoxes in perspective

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Items 201–300 of 367

1. A Review of Telomere Attrition in Cancer and Aging: Current Molecular Insights and Future Therapeutic Approaches
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2. Enhancer of zeste homolog 2 depletion induces cellular senescence via histone demethylation along the INK4/ARF locus
   Bai Jie, Chang Weilong, Ming Cai, Fei Xu, Liu Xinghua, Chen Junhua, Wang Guobin, Kaixiong Tao, Shuai Xiaoming · 2015 · The International Journal of Biochemistry & Cell Biology
3. Senescence as A Consequence of Ginsenoside Rg1Response on K562 Human Leukemia Cell Line
   Jun Liu, Shizhong Cai, Yue Zhou, Xian-Ping Zhang, Dianfeng Liu, Rong Jiang, Yaping Wang · 2012 · Asian Pacific Journal of Cancer Prevention
4. Helicobacter pylori-induced premature senescence of extragastric cells may contribute to chronic skin diseases
   Anna Lewińska, Maciej Wnuk · 2017 · Biogerontology
5. The role of autophagy in escaping therapy-induced polyploidy/senescence
   Magdalena Dudkowska, Karolina Staniak, Agnieszka Bojko, Ewa Sikora · 2021 · Advances in cancer research
6. Genome instability: Linking ageing and brain degeneration
   Ari Barzilai, Björn Schumacher, Yosef Shiloh · 2016 · Mechanisms of Ageing and Development
7. Fanconi anemia proteins counteract the implementation of the oncogene-induced senescence program
   Anne Helbling-Leclerc, Françoise Dessarps-Freichey, Caroline Evrard, Filippo Rosselli · 2019 · Scientific Reports
8. The Role of Cellular Senescence in the Gastrointestinal Mucosa
   Joshua D. Penfield, Marlys A. Anderson, Lori L. Lutzke, Kenneth K. Wang · 2013 · Gut and Liver
9. Aging Biomarkers and Novel Targets for Anti-Aging Interventions
   Kang Xu, Yannan Guo, Zhongchi Li, Zhao Wang · 2019 · Advances in experimental medicine and biology
10. Yearning for machine learning: applications for the classification and characterisation of senescence
    Bethany K. Hughes, Ryan Wallis, Cleo L. Bishop · 2023 · Cell and Tissue Research
11. Bmi1 limits dilated cardiomyopathy and heart failure by inhibiting cardiac senescence
    Ileana B. Gonzalez-Valdes, Isabel Hidalgo, Arturo Bujarrabal-Dueso, Enrique Lara‐Pezzi, Laura Padrón-Barthe, Pablo García‐Pavía, Pablo Gómez‐del Arco, Juan Miguel Redondo, Jesús Ruı́z-Cabello, Luis Jesús Jiménez‐Borreguero et al. · 2015 · Nature Communications · Retracted
12. Energy metabolism homeostasis in cardiovascular diseases.
    Lu-Yun Wang, Chen Chen · 2021 · PubMed Central
13. Cancer as a disease of tissue pattern formation
    Fabio Marongiu, Silvia Doratiotto, Marcella Sini, Maria Paola Serra, Ezio Laconi · 2012 · Progress in Histochemistry and Cytochemistry
14. Regulation and function of Myb-binding protein 1A (MYBBP1A) in cellular senescence and pathogenesis of head and neck cancer
    Babitha George, Dominik Horn, Pilar Bayo, Karim Zaoui, Christa Flechtenmacher, Niels Grabe, Peter K. Plinkert, Valery Krizhanovsky, Jochen Heß · 2014 · Cancer Letters
15. Dual mTORC1/C2 inhibitors: gerosuppressors with potential anti-aging effect
    Pedro Sousa‐Victor, Laura García‐Prat, Pura Muñoz‐Cánoves · 2015 · Oncotarget
16. Miz1 Is a Critical Repressor of cdkn1a during Skin Tumorigenesis
    Jan Hönnemann, Adrián Sanz‐Moreno, Elmar Wolf, Martin Eilers, Hans‐Peter Elsässer · 2012 · PLoS ONE
17. Chemiluminescent Detection of Senescence-Associated β Galactosidase
    Vinícius Bassaneze, Ayumi Aurea Miyakawa, José Eduardo Krieger · 2012 · Methods in molecular biology
18. Adipose Tissue: A Tertiary Lymphoid Organ: Does It Change with Age?
    Daniela Frasca, Bonnie B. Blomberg · 2019 · Gerontology
19. LRP5 in age-related changes in vascular and alveolar morphogenesis in the lung
    Akiko Mammoto, Megan Muyleart, Tadanori Mammoto · 2019 · Aging
20. Alterations in Gene Array Patterns in Dendritic Cells from Aged Humans
    Jia-ning Cao, Anshu Agrawal, Edward H. Sharman, Zhenyu Jia, Sudhir Gupta · 2014 · PLoS ONE
21. Improvement of non-alcoholic steatohepatitis by hepatocyte-like cells generated from iPSCs with Oct4/Sox2/Klf4/Parp1
    Yueh Chien, Chi-Shuan Huang, Hsin-Chi Lin, Kai‐Hsi Lu, Ping‐Hsing Tsai, Ying-Hsiu Lai, Kuan-Hsuan Chen, Shou‐Dong Lee, Yi‐Hsiang Huang, Chien‐Ying Wang · 2017 · Oncotarget
22. Signs of Similarities and Differences in Cellular Models of Aging: A Scoping Review
    Моргунова Галина Васильевна, Alexander N. Khokhlov · 2022 · Moscow University Biological Sciences Bulletin
23. The influence of photodynamic therapy with 5-aminolevulinic acid on senescent skin cancer cells
    Mantas Grigalavicius, Marina Juraleviciute, Mateusz Kwitniewski, Asta Juzeniene · 2016 · Photodiagnosis and Photodynamic Therapy
24. Cellular senescence and autophagy of myoepithelial cells are involved in the progression of in situ areas of carcinoma ex-pleomorphic adenoma to invasive carcinoma. An in vitro model
    Carolina Amália Barcellos Silva, Elizabeth Ferreira Martinez, Ana Paula Dias Demasi, Albina Altemani, Jeruza P. Bossonaro, Ney Soares de Araújo, Vera Cavalcanti de Araújo · 2015 · Journal of Cell Communication and Signaling
25. Twist1 signaling in age-dependent decline in angiogenesis and lung regeneration
    Kathryn Hendee, Tendai Hunyenyiwa, Kienna Matus, Maria Toledo, Akiko Mammoto, Tadanori Mammoto · 2021 · Aging
26. Role of ADAM17 in the non-cell autonomous effects of oncogene-induced senescence.
    Morancho, Beatriz, Martínez-Barriocanal, Águeda, Villanueva, Josep, Arribas, Joaquín · 2015 · Breast Cancer Research
27. DNA double-strand break repair is impaired in presenescent Syrian hamster fibroblasts
    Ljudmila Solovjeva, Denis Firsanov, А. А. Василишина, Vadim O. Chagin, Nadezhda Pleskach, Andrey Kropotov, Maria Svetlova · 2015 · BMC Molecular Biology
28. Inhibitory effects of quercetagetin 3,4′-dimethyl ether purified from Inula japonica on cellular senescence in human umbilical vein endothelial cells
    Hyo Hyun Yang, Haiyan Zhang, Jong‐Keun Son, Jae‐Ryong Kim · 2015 · Archives of Pharmacal Research
29. PDCD4 is a CSL associated protein with a transcription repressive function in cancer associated fibroblast activation
    Jo, Seung-Hee, Kim, Dong Eun, Clocchiatti, Andrea, Dotto, G. Paolo · 2016 · Oncotarget
30. Reduced leukocyte telomere lengths and sirtuin 1 gene expression in long‐term survivors of type 1 diabetes: A Dialong substudy
    Trine Baur Opstad, Tore Julsrud Berg, Kristine Bech Holte, Harald Arnesen, Svein Solheim, Ingebjørg Seljeflot · 2020 · Journal of Diabetes Investigation
31. Random mtDNA mutations modulate proliferation capacity in mouse embryonic fibroblasts
    Alexandra Kukat, Daniel Edgar, Ivana Bratic, Priyanka Maiti, Aleksandra Trifunović · 2011 · Biochemical and Biophysical Research Communications
32. Contact inhibition against senescence
    Peiqing Sun · 2014 · Oncotarget
33. Senescent Astrocytes: A New Player in Brain Aging and Cognitive Decline
    Bruna Pessoa, Lívia de Sá Hayashide, G. R. Dias, Bruno Pontes, Rafael Serafim Pinto, Luan Pereira Diniz · 2026 · Brain Sciences
34. Genetic and Epigenetic Inheritance at Telomeres
    Evan H. Lister‐Shimauchi, Ben McCarthy, Michael J. Lippincott, Shawn Cameron Ahmed · 2022 · Epigenomes
35. New Insight into the Potential Protective Function of Sulforaphene against ROS−Mediated Oxidative Stress Damage In Vitro and In Vivo
    Bo Zhang, Pengtao Liu, Huakang Sheng, Yang Guo, Yongzhi Han, Lin Suo, Qipeng Yuan · 2023 · International Journal of Molecular Sciences
36. Cellular Senescence-Inducing Small Molecules for Cancer Treatment
    Peng Liu, Ziwen Lu, Yanfang Wu, Dongsheng Shang, Zhicong Zhao, Yanting Shen, Yafei Zhang, Feifei Zhu, Hanqing Liu, Zhigang Tu · 2018 · Current Cancer Drug Targets
37. Is Chronic Obstructive Pulmonary Disease a Disease of Aging?
    Manuel G. Cosío, Riccardo Cazzuffi, Marina P. Saetta · 2014 · Respiration
38. Identification of novel therapeutic targets in the secretome of ionizing radiation-induced senescent tumor cells
    Hyun Jung Hwang, Seung Hee Jung, Hyung‐Chul Lee, Na Kyung Han, In Hwa Bae, Minyoung Lee, YOUNG-HOON HAN, Young‐Sun Kang, SU-JAE LEE, Heon Joo Park et al. · 2015 · Oncology Reports
39. Atrophied Thymus, a Tumor Reservoir for Harboring Melanoma Cells
    Olga S. Sizova, Denis Kuriatnikov, Ying Min Liu, Dong‐Ming Su · 2018 · Molecular Cancer Research
40. Activity and intracellular localization of senescence-associated β-galactosidase in aging Xenopus oocytes and eggs
    Alexander A. Tokmakov, Ken‐ichi Sato · 2019 · Experimental Gerontology
41. Distinctive Gene Expression Profiles and Biological Responses of Skin Fibroblasts to Nicotinamide Mononucleotide: Implications for Longevity Effects on Skin
    Seongsu Kang, Ji-Won Park, Eunbyul Cho, Dohyun Kim, Sanghyun Ye, Eui Taek Jeong, Seung‐Hyun Jun, Nae Gyu Kang · 2025 · Biomedicines
42. Immunoregulatory network and cancer-associated genes: molecular links and relevance to aging
    Robi Tăcutu, Arie Budovsky, Hagai Yanai · 2011 · DOAJ (DOAJ: Directory of Open Access Journals)
43. Loss of Pla2r1 decreases cellular senescence and age‐related alterations caused by aging and Western diets
    Amélie Massemin, Delphine Goehrig, Jean‐Michel Flaman, Sara Jaber, Audrey Griveau, Sophia Djebali, Élisabeth Marcos, Lea Francoise Payen, Jacqueline Marvel, Romain Parent et al. · 2023 · Aging Cell
44. Adipose tissue aging as a risk factor for metabolic organ abnormalities: mechanistic insights and the role of exercise interventions
    Shaokai Tang, Yuanwen Geng, Qinqin Lin · 2025 · Lipids in Health and Disease
45. IRF1 Mediates Growth Arrest and the Induction of a Secretory Phenotype in Alveolar Epithelial Cells in Response to Inflammatory Cytokines IFNγ/TNFα
    Giulia Recchia Luciani, Amelia Barilli, Rossana Visigalli, Roberto Sala, Valeria Dall’Asta, Bianca Maria Rotoli · 2024 · International Journal of Molecular Sciences
46. Biomarkers, interventions and healthy ageing
    Almas Kenessary, Zhaxybay Sh. Zhumadilov, Talgat S. Nurgozhin, David Kipling, Mark S. Yeoman, Lynne S. Cox, Elizabeth L. Ostler, Richard Faragher · 2012 · New Biotechnology
47. Elevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late Midlife
    Christiane Elisabeth Sørensen, Katerina Tritsaris, Jesper Reibel, Martin Lauritzen, Erik Lykke Mortensen, Merete Osler, Anne Marie Lynge Pedersen · 2016 · PLoS ONE
48. Identification of senescence related hub genes and potential therapeutic compounds for dilated cardiomyopathy via comprehensive transcriptome analysis
    Chong Du, Sibo Wang, Xinying Shi, Peng Jing, Hao Wang, Hao Wang · 2024 · Computers in Biology and Medicine
49. Targeted Therapeutics Delivery by Exploiting Biophysical Properties of Senescent Cells
    Jessalyn Low, Brian Chan, Andy Kah Ping Tay · 2021 · Advanced Functional Materials
50. Effects of Aging on Metabolic Characteristics of Human B Cells
    Daniela Frasca, Suresh Pallikkuth, Savita G. Pahwa · 2022 · JAIDS Journal of Acquired Immune Deficiency Syndromes
51. Reducing the aneuploid cell burden – cell competition and the ribosome connection
    Nicholas E. Baker, Cristina Montagna · 2022 · Disease Models & Mechanisms
52. Genome wide expression analysis of radiation-induced DNA damage responses in isogenic HCT116 p53+/+ and HCT116 p53−/− colorectal carcinoma cell lines
    Theres Lindgren, Torgny I. Stigbrand, Aino Råberg, Katrine Riklund, Lennart F. Johansson, David Eriksson · 2014 · International Journal of Radiation Biology
53. Telomere length and oxidative stress variations in a murine model of Alzheimer’s disease progression
    Martínez‐González, Katia, Islas‐Hernández, Azul, Martínez‐Ezquerro, José Darío, Bermúdez‐Rattoni, Federico, Garcia‐delaTorre, Paola · 2020 · European Journal of Neuroscience
54. Unveiling the complexity of cellular senescence in cancers: From mechanism to therapeutic opportunities
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55. Impaired B Cell Function in Mice Lacking Perforin-2
    Daniela Frasca, Alain Diaz, Maria Romero, Thomas Vazquez, Nataša Štrbo, Laura Romero, Ryan McCormack, Eckhard R. Podack, Bonnie B. Blomberg · 2020 · Frontiers in Immunology
56. Malglycemia and Cancer: Introduction to a Conceptual Model
    Marilyn J. Hammer, Joachim G. Voss · 2012 · Oncology nursing forum
57. Multiwalled Carbon Nanotubes Induce Fibrosis and Telomere Length Alterations
    Mayes Alswady‐Hoff, Johanna Samulin Erdem, Mona Aleksandersen, Kristine Haugen Anmarkrud, Øivind Skare, F.‐C. Lin, Vincent Simensen, Yke Jildouw Arnoldussen, Vidar Skaug, Erik Ropstad et al. · 2022 · International Journal of Molecular Sciences
58. Nicotinamide and calcipotriol counteract UVB-induced photoaging on primary human dermal fibroblasts
    Lara Camillo, Laura Cristina Gironi, Elia Esposto, Elisa Zavattaro, Paola Savoia · 2022 · Journal of Photochemistry and Photobiology
59. Cardiac Stem Cell Senescence
    Daniela Cesselli, Federica D’Aurizio, Patrizia Marcon, Natascha Bergamin, Carlo Alberto Beltrami, Antonio Paolo Beltrami · 2013 · Methods in molecular biology
60. Inflammation, Aging and Cancer: Friend or Foe?
    Mahin Khatami · 2012 · InTech eBooks
61. Modulation of Cellular Senescence in HEK293 and HepG2 Cells by Ultrafiltrates UPla and ULu Is Partly Mediated by Modulation of Mitochondrial Homeostasis under Oxidative Stress
    Jun-Xian Zhou, Kang Liu, Chris Bauer, Gerald Bendner, Heike Dietrich, Jakub Peter Slivka, Michaël Wink, Michelle BF Wong, Mike K. S. Chan, Thomas Skutella · 2023 · International Journal of Molecular Sciences
62. Inflammaging
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63. Aging and the Host Response to Implanted Biomaterials
    Archana N. Rao, M. Avula, David W. Grainger · 2015 · Elsevier eBooks
64. Resistance Mechanisms to Cyclin-Dependent Kinase Inhibitors
    Wiedemeyer, Wolf Ruprecht · 2018 · Resistance to Targeted Anti-Cancer Therapeutics
65. Sex hormones and gender differences in immune responses and anticancer immunity: a comprehensive review
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66. Emerging Therapeutic Strategies in Anti‐Aging Medicine: A Comprehensive Review
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67. ATRX loss inhibits DDR to strengthen radio-sensitization in p53-deficent HCT116 cells
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68. Decline in regeneration during aging: Appropriateness or stochastics?
    Alexander N. Khokhlov · 2013 · Russian Journal of Developmental Biology
69. CSL-p53: From senescence to CAF activation
    Maria-Giuseppina Procopio, Csaba László, Gian Paolo Dotto · 2016 · Cell Cycle
70. Anti-Migratory Effects of 4′-Geranyloxyferulic Acid on LPS-Stimulated U937 and HCT116 Cells via MMP-9 Down-Regulation: Involvement of ROS/ERK Signaling Pathway
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71. Senescence-Associated miRNAs and Their Role in Pancreatic Cancer
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72. The protective effects of Phoenixin-20 in tumor necrosis factor α (TNF-α)-induced cell senescence of rheumatoid arthritis fibroblast-like synoviocytes (FLS)
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73. Performance status in elderly patients with acute myeloid leukemia: exploring gene expression signatures of cytokines and chemokines.
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74. Hypothalamic Pathophysiology in the Neuroimmune,Dysmetabolic and Longevity Complications of Chronic Opiate Dependency
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75. Targeted Senolytic Strategies Based on the Senescent Surfaceome
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76. An effective system for senescence modulating drug development using quantitative high-content analysis and high-throughput screening
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77. Rhythms of life: melatonin, nutrition, sleep, and antioxidant strategies for healthy aging
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78. Modifiable Factors Influencing Telomere Length and Aging
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79. Telomere and Telomerase Biology in Cardiovascular Disease: A State-of-the-art Review and Outlook
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80. Senotherapy for attenuation of cellular senescence in aging and organ implantation
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81. Methods and sensors for functional genomic studies of cell-cycle transitions in single cells
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82. The interactome era: Integrating RNA-seq, proteomics, and network biology to decode cellular senescence
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83. New Targets for the Identification of an Anti-Inflammatory Anti-Senescence Activity
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84. Loss of ALDH2 accelerates the progression of pulmonary arterial hypertension through the 4-HNE/ERK1/2-p16 signaling pathway
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85. Decreased telomerase activity and shortened telomere length in infants whose mothers have gestational diabetes mellitus and increased severity of telomere shortening in male infants
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86. Angiogenic Activity of the Peritoneal Mesothelium: Implications for Peritoneal Dialysis
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87. Aging Aorta—Cellular Mechanisms
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88. Senolysis and Senostasis Through the Plasma Membrane
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89. Progress in Peritoneal Dialysis
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90. Inflammaging
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91. Targeting Genome Stability to Mitigate Human Aging and Disease
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92. In Vitro Treatment with Metformin Significantly Reduces Senescent B Cells Present in the Adipose Tissue of People with Obesity
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93. Major Differences between Tumor and Normal Human Cell Fates after Exposure to Chemotherapeutic Monofunctional Alkylator
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94. Healthspan Extension through Innovative Genetic Medicines
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95. MK3 Modulation Affects BMI1-Dependent and Independent Cell Cycle Check-Points
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96. Detection of Nuclear Envelope Alterations in Senescence
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97. Piwi mutant germ cells transmit a form of heritable stress that promotes longevity
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98. Advances in Molecular Research of Tracheobronchial Tree Aging: A Systematic Review
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99. Telomere Biology and Vascular Aging
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100. Systemic inflammation in patients with hypertension and coronary artery disease in different age groups
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