Bupropion, a brief history of seizure risk
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The use of bupropion immediate release (IR) in dosages more than 450 mg may cause a 10-fold increase of the estimated seizure incidence.
“The use of bupropion immediate release (IR) in dosages more than 450 mg may cause a 10-fold increase of the estimated seizure incidence.50”
From Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review (2018) · cites this paper as [50]
Cites
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Seizures and bupropion: a review.
Davidson, J. R. T. (1989) · PubMed · Cited by 237 · see citing works
Seizures associated with antidepressants: a review.
Rosenstein, D. L., Nelson, J. C., & Jacobs, S. (1993) · PubMed · Cited by 215 · see citing works
Treatment of bulimia with bupropion: a multicenter controlled trial.
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A 2—5 year follow-up study of patients treated for bulimia
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Seizures during tricyclic therapy
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The pharmacological treatment of depression in adults with epilepsy
Mula, M., Schmitz, B., & Sander, J. W. A. S. (2008) · Expert Opinion on Pharmacotherapy · doi:10.1517/14656560802587024 · Cited by 41 · see citing works
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Bitemporal Epileptiform Discharges Induced by Bupropion: A Case Report
Shah, G. D., & Hirsch, L. J. (2001) · Clinical Neuropharmacology · doi:10.1097/00002826-200109000-00009 · Cited by 11 · see citing works
Another case of extended-release bupropion-induced seizure.
Rosoff, D. M. (2008) · PubMed · Cited by 5 · see citing works
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Addressing the Side Effects of Contemporary Antidepressant Drugs: A Comprehensive Review
Wang, S.-M., Han, C., Bahk, W.-M., Lee, S.-J., Patkar, A. A., Masand, P. S., & Pae, C.-U. (2018) · Chonnam Medical Journal · doi:10.4068/cmj.2018.54.2.101 · Cited by 299 · see citing works
- Authors
- Tripp, A. C.
- Affiliations
- University of Pittsburgh Medical Center (US)
- Corresponding author
- Tripp, Adam C.
- Venue
- General Hospital Psychiatry
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 32
- Issue
- 2
- Pages
- 216-217
- ISSN
- 0163-8343 (ISSN-L)
- OpenAlex
- W2032214452
- Cited by
- 26
- References
- 13
- Citations by year
- 2025: 1 · 2024: 2 · 2023: 3 · 2022: 2 · 2021: 2 · 2020: 2 · 2019: 2 · 2018: 3 · 2016: 2 · 2015: 2 · 2014: 2 · 2012: 1
- FWCI
- 0.41
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- General Hospital Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Electroconvulsive Therapy Studies
- Health Sciences › Medicine › Psychiatry and Mental health › Epilepsy research and treatment
- Health Sciences › Medicine › Pharmacology › Treatment of Major Depression
- Keywords
- bupropion, seizure risk, antipsychotic adverse effects
- MeSH terms
- Drug Administration Schedule, Epilepsy, Tonic-Clonic, Humans, Incidence, Bupropion, Drug Monitoring, Risk Assessment, Antidepressive Agents, Second-Generation, Bulimia Nervosa
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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