Cited by 247Substance Abuse Treatment and OutcomesOpioid Use Disorder TreatmentYouth, Drugs, and Violence

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Gender effects on drug use, abuse, and dependence: A special analysis of results from the national survey on drug use and health

Cotto, Jessica H., Davis, Elisabeth, Dowling, Gayathri J., Elcano, Jennifer C., Staton, Anna B., Weiss, Susan R.B.·2010·Gender Medicine

DOI 10.1016/j.genm.2010.09.004

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Abstract

Background Gender is increasingly being studied for risk and protective factors underlying substance abuse and addiction. Objective The aim of this study was to assess gender differences in rates of substance abuse and dependence among drug users. Methods A national population sample was examined, focusing on 2 age groups (youths, aged 12-17 years, and young adults, aged 18-25 years) and several commonly abused substances (alcohol, marijuana, and nonmedical prescription medication use). Combined annual data from the National Survey on Drug Use and Health (NSDUH), aggregated from 2002-2005, were used for gender comparisons of rates of substance use, as well as abuse and dependence, among users. Results Overall rates of substance use were significantly higher for males than for females (P < 0.01 for all substances except sedatives and tranquilizers); however, patterns of use, abuse, or dependence among users differed by age group and drug. Interestingly, patterns for youths differed from the overall population and from young adults. Girls exceeded boys in their use of alcohol (P < 0.01) and their nonmedical use of psychotherapeutics (ie, prescription-type pain relievers, stimulants, tranquilizers, sedatives) (P < 0.01); among users, girls were significantly more likely to be dependent on the latter (P < 0.01). Boys reported significantly greater use and abuse of and dependence on marijuana (P < 0.01). In the young adults, the proportion of female users reporting dependence on cocaine or psychotherapeutics was significantly higher than for male users (P < 0.01), who nonetheless reported significantly greater use of these drugs (P < 0.01). Among users, males generally exceeded females in meeting abuse criteria (P < 0.01 for marijuana among 12- to 17-year-olds and for alcohol, marijuana, and psychotherapeutics among 18- to 25-year-olds), with some exceptions mainly in the youngest cohort. Conclusions In this national population sample of youths and young adults, these findings suggest that gender, age, and substance of abuse may all play a role in the observed patterns of drug use, abuse, and dependence. Understanding the reasons for these differences and continuing to evaluate these patterns over time could help in the development of targeted and more effective prevention and treatment interventions.

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Authors: Cotto, J. H., Davis, E., Dowling, G. J., Elcano, J. C., Staton, A. B., & Weiss, S. R. B.
Affiliations: National Institute on Drug Abuse (US)
Corresponding author: Elcano, Jennifer C.
ORCID: Davis, Elisabeth
Dowling, Gayathri J.
Weiss, Susan R.B.
Venue: Gender Medicine
Publisher: Elsevier BV
Published: 2010-10
Volume: 7
Issue: 5
Pages: 402-413
ISSN: 1550-8579 (ISSN-L)
DOI: 10.1016/j.genm.2010.09.004
OpenAlex: W1998881571
Cited by: 247
References: 22
Citations by year: 2026: 7 · 2025: 13 · 2024: 13 · 2023: 24 · 2022: 16 · 2021: 22 · 2020: 24 · 2019: 14 · 2018: 14 · 2017: 18 · 2016: 19 · 2015: 21 · 2014: 15 · 2013: 9 · 2012: 12
FWCI: 5.90
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Gender Medicine (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Opioid Use Disorder Treatment
Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Youth, Drugs, and Violence
Keywords: gender differences, substance use, substance abuse, substance dependence, youth, young adults, alcohol consumption, cannabis use, nonmedical prescription drug use, psychotherapeutics, cocaine, age differences
MeSH terms: Adolescent, Adult, Alcoholism, Marijuana Abuse, Child, Female, Health Surveys, Humans, Male, Psychotropic Drugs, Sex Factors, United States, Age Distribution, Cocaine-Related Disorders, Young Adult

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Gender effects on drug use, abuse, and dependence: A special analysis of results from the national survey on drug use and health

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