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Cited by 429Vector-borne infectious diseasesViral Infections and VectorsBartonella species infections research

Human Granulocytic Anaplasmosis

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Bakken, Johan S., Dumler, J. Stephen·2015·Infectious Disease Clinics of North America
DOI 10.1016/j.idc.2015.02.007PMC PMC4441757
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Abstract

Human granulocytic anaplasmosis, a deer tick-transmitted rickettsial infection caused by Anaplasma phagocytophilum, is a common cause of undifferentiated fever in the northeast and upper Midwest United States. Patients are often initially diagnosed with a mild viral infection, and illness readily resolves in most cases. However, as many as 3% develop life-threatening complications and nearly 1% die from the infection. Although coinfections with Borrelia burgdorferi and Babesia microti occur, there is little evidence to suggest synergism of disease or a role for A phagocytophilum in chronic illness. No vaccine is available.

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  • A. phagocytophilum is the etiologic agent for Human Granulocytic Anaplasmosis (HGA), which occurs in America, Europe and Asia.

    “A. phagocytophilum is the etiologic agent for Human Granulocytic Anaplasmosis (HGA), which occurs in America, Europe and Asia [31].”

    From Tick-borne pathogens in ticks collected from dogs, Latvia, 2011–2016 (2019) · cites this paper as [31]

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Authors
Bakken, J. S., & Dumler, J. S.
Affiliations
  • University of Minnesota (US)
  • University of Maryland, Baltimore (US)
Corresponding author
Dumler, J. Stephen
ORCID
Dumler, J. Stephen
Venue
Infectious Disease Clinics of North America
Publisher
Elsevier BV
Published
2015-06
Volume
29
Issue
2
Pages
341-355
ISSN
0891-5520 (ISSN-L)
DOI
10.1016/j.idc.2015.02.007
PMC
PMC4441757
OpenAlex
W2075556106
Cited by
429
References
0
Citations by year
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FWCI
4.56
Type
journal article
Language
en
Open access
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Infectious Disease Clinics of North America (publishedVersion)
  • PubMed (publishedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Institutes of Health (5r01ai044102-19)
  • National Institute of Allergy and Infectious Diseases (R01 AI44102, R01-AI044102)
Topics
  • Life Sciences › Immunology and Microbiology › Parasitology › Vector-borne infectious diseases
  • Health Sciences › Medicine › Infectious Diseases › Viral Infections and Vectors
  • Life Sciences › Immunology and Microbiology › Parasitology › Bartonella species infections research
Keywords
human granulocytic anaplasmosis, Anaplasma phagocytophilum, Ixodes scapularis, rickettsial infection, undifferentiated fever, tick-borne diseases, disease severity, mortality, vaccines
MeSH terms
Anaplasmosis, Fever, Granulocytes, Humans, Risk Factors, Anaplasma phagocytophilum

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