Chloroquine and hydroxychloroquine as available weapons to fight COVID-19

Remdesivir and chloroquine effectively inhibit the recently emerged novel coronavirus (2019-nCoV) in vitro

Wang, M., Cao, R., Zhang, L., Yang, X., Liu, J., Xu, M., Shi, Z., Hú, Z., Zhong, W., & Xiao, G. (2020) · Cell Research · doi:10.1038/s41422-020-0282-0 · Cited by 6,994

Breakthrough: Chloroquine phosphate has shown apparent efficacy in treatment of COVID-19 associated pneumonia in clinical studies

Gao, J., Tian, Z., & Yang, X. (2020) · BioScience Trends · doi:10.5582/bst.2020.01047 · Cited by 2,592

Chloroquine is a potent inhibitor of SARS coronavirus infection and spread

Vincent, M. J., Bergeron, É., Benjannet, S., Erickson, B. R., Rollin, P. E., Ksiazek, T. G., Seidah, N. G., & Nichol, S. T. (2005) · Virology Journal · doi:10.1186/1743-422x-2-69 · Cited by 1,831

Screening of an FDA-Approved Compound Library Identifies Four Small-Molecule Inhibitors of Middle East Respiratory Syndrome Coronavirus Replication in Cell Culture

de Wilde, A. H., Jochmans, D., Posthuma, C. C., Zevenhoven-Dobbe, J. C., van Nieuwkoop, S., Bestebroer, T. M., van den Hoogen, B. G., Neyts, J. H., & Snijder, E. J. (2014) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.03011-14 · Cited by 731

Whipple's Disease

Fenollar, F., Puéchal, X., & Raoult, D. (2007) · New England Journal of Medicine · doi:10.1056/nejmra062477 · Cited by 651

In vitro inhibition of severe acute respiratory syndrome coronavirus by chloroquine

Keyaerts, E., Vijgen, L., Maes, P., Neyts, J. H., & Ranst, M. A. V. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.08.085 · Cited by 644

New insights into the antiviral effects of chloroquine

Savarino, A., Trani, L. D., Donatelli, I., Cauda, R., & Cassone, A. (2006) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(06)70361-9 · Cited by 570

Chloroquine analogues in drug discovery: new directions of uses, mechanisms of actions and toxic manifestations from malaria to multifarious diseases

Al‐Bari, M. A. A. (2015) · Journal of Antimicrobial Chemotherapy · doi:10.1093/jac/dkv018 · Cited by 477

Chloroquine for the 2019 novel coronavirus SARS-CoV-2

Colson, P., Rolain, J., & Raoult, D. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105923 · Cited by 471

Recycling of chloroquine and its hydroxyl analogue to face bacterial, fungal and viral infections in the 21st century

Rolain, J., Colson, P., & Raoult, D. (2007) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2007.05.015 · Cited by 408

Main protease inhibitors and drug surface hotspots for the treatment of COVID-19: A drug repurposing and molecular docking approach

Hasan, M., Parvez, M. S. A., Azim, K. F., Imran, M. A. S., Raihan, T., Gulshan, A., Muhit, S., Akhand, M. R. N., Ahmed, S. S. U., & Uddin, M. B. (2021) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2021.111742 · Cited by 25

COVID‐19; current situation and recommended interventions

Saeed, H., Osama, H., Madney, Y. M., Harb, H. S., Abdelrahman, M. A., Ehrhardt, C., & Abdelrahim, M. E. A. (2020) · International Journal of Clinical Practice · doi:10.1111/ijcp.13886 · Cited by 24

In silico study of medicinal plants with cyclodextrin inclusion complex as the potential inhibitors against SARS-CoV-2 main protease (Mpro) and spike (S) receptor

Dermawan, D., Prabowo, B. A., & Rakhmadina, C. A. (2021) · Informatics in Medicine Unlocked · doi:10.1016/j.imu.2021.100645 · Cited by 25

Management of obstetrics and gynaecological patients with COVID-19

Franchi, M. P., Bosco, M., Garzon, S., Laganà, A. S., Cromi, A., Barbieri, B., Raffaelli, R., Tacconelli, E., Scambia, G., & Ghezzi, F. (2020) · Italian Journal of Gynaecology and Obstetrics · doi:10.36129/jog.32.01.01 · Cited by 24

Systematic review and meta-analysis of the effectiveness and safety of hydroxychloroquine in treating COVID-19 patients

Yang, T.-H., Chou, C., Yang, Y., Chien, C., Yarmishyn, A. A., Yang, T.-Y., Liu, C.-H., Chang, K.-J., Yang, Y., & Chang, Y. (2020) · Journal of the Chinese Medical Association · doi:10.1097/jcma.0000000000000425 · Cited by 24

Computational investigation of binding of chloroquinone and hydroxychloroquinone against PLPro of SARS-CoV-2

Patel, D., Athar, M., & Jha, P. (2020) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2020.1844804 · Cited by 21

In vitro Dissolution Profile at Different Biological pH Conditions of Hydroxychloroquine Sulfate Tablets Is Available for the Treatment of COVID-19

Dongala, T., Katari, N. K., Ettaboina, S. K., Krishnan, A., Tambuwala, M. M., & Dua, K. (2021) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2020.613393 · Cited by 24

Identification of SARS‐CoV‐2 Main Protease Inhibitors Using Structure Based Virtual Screening and Molecular Dynamics Simulation of DrugBank Database

Debnath, P., Bhaumik, S., Sen, D., Muttineni, R., & Debnath, S. (2021) · ChemistrySelect · doi:10.1002/slct.202100854 · Cited by 24

Potential strategies for combating COVID-19

Shamim, S., Khan, M., Kharaba, Z. J., Ijaz, M., & Murtaza, G. (2020) · Archives of Virology · doi:10.1007/s00705-020-04768-3 · Cited by 24

High-dose glucocorticoids pulse-therapy for beta-coronaviridae pneumonia: a systematic literature review and case-series of Coronavirus disease-2019

Dolci, G., Cassone, G., Venturelli, F., Besutti, G., Revelli, M., Corsini, R., Sampaolesi, F., Pavone, P., Contardi, G., Riva, N., et al. (2021) · Clinical and Experimental Rheumatology · doi:10.55563/clinexprheumatol/36rs0j · Cited by 23

Recent Developments in the Antimicrobial Potential of Some Nitrogenous Heterocycles and their SAR Studies: A Review

Nehra, B., Kumar, M., Singh, S., Chawla, V., Chawla, P. A., & Grover, P. (2024) · Current Medicinal Chemistry · doi:10.2174/0109298673301266240506083014 · Cited by 23

What to expect from different drugs used in the treatment of COVID-19: A study on applications and in vivo and in vitro results

Marcolino, V. A., Pimentel, T. C., & Barão, C. E. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173467 · Cited by 23

Molecular Docking Studies of some Antiviral and Antimalarial Drugs Via Bindings to 3CL-Protease and Polymerase Enzymes of the Novel Coronavirus (SARS-CoV-2)

(2020) · Biointerface Research in Applied Chemistry · doi:10.33263/briac105.64446459 · Cited by 23

Ayurveda and Allopathic Therapeutic Strategies in Coronavirus Pandemic Treatment 2020

Talwar, S., Sood, S., Kumar, J., Chauhan, R., Sharma, M., & Tuli, H. S. (2020) · Current Pharmacology Reports · doi:10.1007/s40495-020-00245-2 · Cited by 23

COVID-19 Impact on Educational System Globally

Khalil, M. I., Humayun, M., & Jhanjhi, N. Z. (2021) · Studies in systems, decision and control · doi:10.1007/978-3-030-60039-6_13 · Cited by 23

Co-Infection with SARS-COV-2 and Parainfluenza in a young adult patient with pneumonia: Case Report

Rodríguez, J. Á., Rubio-Gomez, H., Roa, A. A., Miller, N., & Eckardt, P. (2020) · IDCases · doi:10.1016/j.idcr.2020.e00762 · Cited by 22

Treatments for COVID-19: emerging drugs against the coronavirus - reply.

Potì, F., Pozzoli, C., Adami, M., Poli, E., & Costa, L. G. (2020) · Acta bio-medica dell'Ateneo parmense/Acta biomedica · doi:10.23750/abm.v91i2.9639 · Cited by 22

COVID-19 Drug Treatment in China

Fan, L., Jiang, S., Yang, X., Wang, Z., & Yang, C. (2020) · Current Pharmacology Reports · doi:10.1007/s40495-020-00218-5 · Cited by 22

Prediction studies of the epidemic peak of coronavirus disease in Japan: From Caputo derivatives to Atangana–Baleanu derivatives

Kumar, P., Rangaig, N. A., Abboubakar, H., Kumar, A., & Manickam, A. (2021) · Advances in Complex Systems · doi:10.1142/s179396232250012x · Cited by 22

Cell and Animal Models for SARS-CoV-2 Research

Bestion, E., Halfon, P., Mezouar, S., & Mège, J. (2022) · Viruses · doi:10.3390/v14071507 · Cited by 24

The ICMR bulletin on targeted hydroxychloroquine prophylaxis for Covid-19: Need to interpret with caution

Dcruz, M. M. (2020) · Indian Journal of Medical Ethics · doi:10.20529/ijme.2020.040 · Cited by 21

Combined Prophylactic and Therapeutic Use Maximizes Hydroxychloroquine Anti-SARS-CoV-2 Effects in vitro

Clementi, N., Criscuolo, E., Diotti, R. A., Ferrarese, R., Castelli, M., Dagna, L., Burioni, R., Clementi, M., & Mancini, N. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.01704 · Cited by 21

Translating bioactive peptides for COVID-19 therapy

Bhullar, K. S., Drews, S. J., & Wu, J. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173661 · Cited by 21

Inhalable Hydroxychloroquine Powders for Potential Treatment of COVID-19

Albariqi, A. H., Chang, R. Y. K., Tai, W., Ke, W.-R., Chow, M. Y. T., Tang, P., Kwok, P. C. L., & Chan, H. (2020) · Journal of Aerosol Medicine and Pulmonary Drug Delivery · doi:10.1089/jamp.2020.1648 · Cited by 21

Potential therapeutic and pharmacological strategies for SARS-CoV2

Ghareeb, D. A., Saleh, S. R., Nofal, M. S., Kaddah, M. M. Y., Hassan, S. F., Seif, I. K., El‐Zahaby, S. A., Khedr, S. M., Kenawy, M. Y., Masoud, A. A., et al. (2021) · Journal of Pharmaceutical Investigation · doi:10.1007/s40005-021-00520-4 · Cited by 21

An Overview on Novel Coronavirus (COVID-19)

Suresh, G. (2020) · Nanomedicine & Nanotechnology Open Access · doi:10.23880/nnoa-16000183 · Cited by 21

Review on development of potential inhibitors of SARS-CoV-2 main protease (MPro)

Katre, S. G., Asnani, A. J., Pratyush, K., Sakharkar, N. G., Bhope, A. G., Sawarkar, K. T., & Nimbekar, V. S. (2022) · Future Journal of Pharmaceutical Sciences · doi:10.1186/s43094-022-00423-7 · Cited by 21

Hydroxychloroquine for treatment of nonsevere COVID‐19 patients: Systematic review and meta‐analysis of controlled clinical trials

Elsawah, H. K., Elsokary, M. A., Elrazzaz, M., & Elshafie, A. H. (2020) · Journal of Medical Virology · doi:10.1002/jmv.26442 · Cited by 20

Implications of myocardial injury in Mexican hospitalized patients with coronavirus disease 2019 (COVID-19)

Aquino‐Bruno, H., Carlos, P. C. J., Antonio, C. R. J., Pulido‐Perez, P., Torres‐Rasgado, E., Morales-Portano, J. D., Benito, G. Á. E., & Alfredo, M. R. J. (2020) · IJC Heart & Vasculature · doi:10.1016/j.ijcha.2020.100638 · Cited by 21

Methods of Synthesis of Remdesivir, Favipiravir, Hydroxychloroquine, and Chloroquine: Four Small Molecules Repurposed for Clinical Trials during the Covid-19 Pandemic

Albujuq, N. R. (2020) · Synthesis · doi:10.1055/s-0040-1707386 · Cited by 20

Available Compounds With Therapeutic Potential Against COVID-19: Antimicrobial Therapies, Supportive Care, and Probable Vaccines

Kumar, R., Srivastava, J. K., Singh, R., Siddiqui, M. H., Mansouri, R. A., Abdulhakim, J. A., Bin-Jumah, M. N., Alkahtani, S. H., Abdel‐Daim, M. M., & Uddin, M. S. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.582025 · Cited by 22

Pragmatic, open-label, single-center, randomized, phase II clinical trial to evaluate the efficacy and safety of methylprednisolone pulses and tacrolimus in patients with severe pneumonia secondary to COVID-19: The TACROVID trial protocol

Solanich, X., Antolí, A., Zamora, N. P., Fanlo‐Maresma, M., Iriarte, A., Mitjavila, F., Capdevila, O., Molina, M., Sabater‐Riera, J., Bas, J., et al. (2021) · Contemporary Clinical Trials Communications · doi:10.1016/j.conctc.2021.100716 · Cited by 20

Drug-Induced Liver Disturbance During the Treatment of COVID-19

Zhai, G., Li, M., Wang, Y., & Wu, J. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.719308 · Cited by 20

Explorations in a galaxy of sialic acids: a review of sensing horizons, motivated by emerging biomedical and nutritional relevance

Guin, S. K., Velasco‐Torrijos, T., & Dempsey, E. (2021) · Sensors & Diagnostics · doi:10.1039/d1sd00023c · Cited by 21

Ivermectin: Potential Role as Repurposed Drug for COVID-19

Dixit, A., Yadav, R., & Singh, A. V. (2020) · Malaysian Journal of Medical Sciences · doi:10.21315/mjms2020.27.4.15 · Cited by 20

Clinical characteristics, treatment regimen and duration of hospitalization among COVID-19 patients in Ghana: a retrospective cohort study.

Ashinyo, M. E., Duti, V., Dubik, S. D., Amegah, K. E., Kutsoati, S., Oduro‐Mensah, E., Puplampu, P., Gyansa‐Lutterodt, M., Darko, D. M., Buabeng, K. O., et al. (2020) · PubMed Central · doi:10.11604/pamj.supp.2020.37.9.25718 · Cited by 21

SARS-CoV-2 (COVID-19) en pacientes con algún grado de inmunosupresión

Cajamarca-Barón, J., Guavita-Navarro, D., Buitrago-Bohórquez, J., Gallego-Cardona, L., Navas, Á., Cubides, H. H., Arredondo, A. M., Escobar, A., & Rojas‐Villarraga, A. (2020) · Reumatología Clínica · doi:10.1016/j.reuma.2020.08.004 · Cited by 21

Molecular recognition in the infection, replication, and transmission of COVID-19-causing SARS-CoV-2: an emerging interface of infectious disease, biological chemistry, and nanoscience

Kumar, P., Sobhanan, J., Takano, Y., & Biju, V. (2021) · NPG Asia Materials · doi:10.1038/s41427-020-00275-8 · Cited by 21

Open questions for harnessing autophagy-modulating drugs in the SARS-CoV-2 war: hope or hype?

Brest, P., Benzaquen, J., Klionsky, D. J., Hofman, P. M., & Mograbi, B. (2020) · Autophagy · doi:10.1080/15548627.2020.1779531 · Cited by 23

Chloroquine in fighting COVID-19: good, bad, or both?

Tang, D., Li, J., Zhang, R., Kang, R., & Klionsky, D. J. (2020) · Autophagy · doi:10.1080/15548627.2020.1796014 · Cited by 20

Novel Antiviral Strategies in the Treatment of COVID-19: A Review

Chen, S., Wang, S.-C., & Chen, Y. (2020) · Microorganisms · doi:10.3390/microorganisms8091259 · Cited by 20

Current status of COVID-19 pandemic; characteristics, diagnosis, prevention, and treatment

Ahangarzadeh, S., Nokhodian, Z., Ranjbar, M. M., Nasri, P., Kassaian, N., Shoaei, P., Vakili, B., Rostami, S., Alibakhshi, A., Yarian, F., et al. (2020) · Journal of Research in Medical Sciences · doi:10.4103/jrms.jrms_476_20 · Cited by 19

COVID-19 Impacts, Diagnosis and Possible Therapeutic Techniques: A Comprehensive Review

Aziz, A., Asif, M., Ashraf, G., Yang, Q., & Wang, S. (2020) · Current Pharmaceutical Design · doi:10.2174/1874467213666201204154239 · Cited by 19

Viscometric and FTIR studies of chloroquine phosphate, acefylline piperazine and gentamicin sulfate in aqueous-polyethylene glycol and aqueous-polyvinyl pyrrolidone at different temperatures

Rehman, W., Masood, S., Begum, S., Chandio, A. D., Khan, S. R., Gulnar, L., Khattak, R., & Khan, M. S. (2021) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2021.103265 · Cited by 19

QSAR modeling, molecular docking and molecular dynamic simulation of phosphorus-substituted quinoline derivatives as topoisomerase I inhibitors

Lahyaoui, M., El-Idrissi, H., Saffaj, T., Ihssane, B., Saffaj, N., Mamouni, R., & Rodi, Y. K. (2023) · Arabian Journal of Chemistry · doi:10.1016/j.arabjc.2023.104783 · Cited by 19

Repurposing clinically available drugs and therapies for pathogenic targets to combat SARS‐CoV‐2

Xue, Y., Mei, H., Chen, Y., Griffin, J. D., Liu, Q., Weisberg, E., & Yang, J. C. (2023) · MedComm · doi:10.1002/mco2.254 · Cited by 20

COVID-19 in Iran, a comprehensive investigation from exposure to treatment outcomesPreprint

Ashraf, M. A., Shokouhi, N., Shirali, E., Tanha, F. D., Memar, O. M., Kamalipour, A., Azarnoush, A., Mabadi, A., Ossareh, A., Sanginabadi, M., et al. (2020) · doi:10.21203/rs.3.rs-26339/v1 · Cited by 19

Brief Report: Retrospective Evaluation on the Efficacy of Lopinavir/Ritonavir and Chloroquine to Treat Nonsevere COVID-19 Patients

Gao, G., Wang, A., Wang, S., Qian, F., Chen, M., Yu, F., Zhang, J., Wang, X., Ma, X., Zhao, T., et al. (2020) · JAIDS Journal of Acquired Immune Deficiency Syndromes · doi:10.1097/qai.0000000000002452 · Cited by 18

Safety and Effectiveness of Hydroxychloroquine and Azithromycin Combination Therapy for Treatment of Hospitalized Patients with COVID-19: A Propensity-Matched Study

Huang, H. D., Jneid, H. M., Aziz, M. S., Ravi, V., Sharma, P. S., Larsen, T. R., Chatterjee, N. A., Saour, B., Aziz, Z. A., Nayak, H. M., et al. (2020) · Cardiology and Therapy · doi:10.1007/s40119-020-00201-7 · Cited by 17

Synthesis, Antimicrobial, and Antibiofilm Activities of Some Novel 7-Methoxyquinoline Derivatives Bearing Sulfonamide Moiety against Urinary Tract Infection-Causing Pathogenic Microbes

Ghorab, M. M., Soliman, A. M., El-Sayyad, G. S., Abdel-Kader, M. S., & El-Batal, A. I. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24108933 · Cited by 18

Coronavirus disease ( COVID ‐19): An updated review based on current knowledge and existing literature for dermatologists

Kaur, I., Sharma, A., Jakhar, D., Das, A., Aradhya, S. S., Sharma, R., Jindal, V., & Mhatre, M. (2020) · Dermatologic Therapy · doi:10.1111/dth.13677 · Cited by 17

COVID-19: therapeutic approaches description and discussion

TRINDADE, G. G., Caxito, S. M. C., Xavier, A. R. E. O., Xavier, M. A. D. S., & Brandão, F. (2020) · Anais da Academia Brasileira de Ciências · doi:10.1590/0001-3765202020200466 · Cited by 18

Beta-thalassemia may protect against COVID 19

Drouin, E. (2020) · Medical Hypotheses · doi:10.1016/j.mehy.2020.110014 · Cited by 18

Immune Modulation as a Therapeutic Option During the SARS-CoV-2 Outbreak: The Case for Antimalarial Aminoquinolines

Vitte, J., Michel, M., Mezouar, S., Diallo, A. B., Boumaza, A. F., Mège, J., & Desnues, B. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.02159 · Cited by 18

Antidepressants and Antipsychotic Agents as Repurposable Oncological Drug Candidates

Antoszczak, M., Markowska, A., Markowska, J., & Huczyński, A. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200907141452 · Cited by 18

The Practicality of Deep Learning Algorithms in COVID-19 Detection: Application to Chest X-ray Images

Alorf, A. A. (2021) · Algorithms · doi:10.3390/a14060183 · Cited by 17

Commentary on “Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open label non-randomized clinical trial” by Gautret et al

Toumi, M., & Aballéa, S. (2020) · Journal of Market Access & Health Policy · doi:10.1080/20016689.2020.1758390 · Cited by 18

Insights in Chloroquine Action: Perspectives and Implications in Malaria and COVID‐19

Pillat, M. M., Krüger, A., Guimarães, L. M. F., Lameu, C., de Souza, E. E., Wrenger, C., & Ulrich, H. (2020) · Cytometry Part A · doi:10.1002/cyto.a.24190 · Cited by 17

Incidence of coronavirus disease (COVID-19) and countries affected by malarial infections

Ahmed, A. E. (2020) · Travel Medicine and Infectious Disease · doi:10.1016/j.tmaid.2020.101693 · Cited by 17

Fármacos prometedores y potenciales para el tratamiento de COVID-19

Moneriz, C., & Castro-Salguedo, C. (2020) · Revista chilena de infectología · doi:10.4067/s0716-10182020000300205 · Cited by 23

Pharmacological insight into potential therapeutic agents for the deadly Covid-19 pandemic

Bhandari, R., Khanna, G., & Kuhad, A. (2020) · European Journal of Pharmacology · doi:10.1016/j.ejphar.2020.173643 · Cited by 17

Therapeutic role of traditionally used Indian medicinal plants and spices in combating COVID-19 pandemic situation

Nath, M., & Debnath, P. (2022) · Journal of Biomolecular Structure and Dynamics · doi:10.1080/07391102.2022.2093793 · Cited by 18

Corona Virus Disease (COVID-19): A past and Present Prospective

Talele, S. G., Ahire, E. D., Surana, K. R., Sonawane, V. N., & Talele, G. S. (2022) · Asian Journal of Pharmaceutical Research · doi:10.52711/2231-5691.2022.00008 · Cited by 17

Novel synthesis of quinoline chalcone derivatives - Design, synthesis, characterization and antimicrobial activity

Kumar, C. H. P., Katagi, M. S., & Nandeshwarappa, B. P. (2022) · Chemical Data Collections · doi:10.1016/j.cdc.2022.100955 · Cited by 17

Dual action anti‐inflammatory/antiviral isoquinoline alkaloids as potent naturally occurring anti‐SARS‐CoV ‐2 agents: A combined pharmacological and medicinal chemistry perspective

Valipour, M., Hosseini, A., Sotto, A. D., & Irannejad, H. (2023) · Phytotherapy Research · doi:10.1002/ptr.7833 · Cited by 17

COVID-19: the epidemiology and treatment

Qu, L., Li, J., & Ren, H. (2020) · British Journal of Hospital Medicine · doi:10.12968/hmed.2020.0580 · Cited by 17

Targeting COVID-19 in Parkinsons Patients: Drugs Repurposed

Anwar, F., Naqvi, S., Al-Abbasi, F. A., Neelofar, N., Kumar, V., Sahoo, A., & Kamal, M. A. (2020) · Current Medicinal Chemistry · doi:10.2174/0929867327666200903115138 · Cited by 17

Development and validation of an LC-MS/MS method for determination of hydroxychloroquine, its two metabolites, and azithromycin in EDTA-treated human plasma

Sok, V., Marzan, F., Gingrich, D. J., Aweeka, F. T., & Huang, L. (2021) · PLoS ONE · doi:10.1371/journal.pone.0247356 · Cited by 17

Current pharmacological modalities for management of novel coronavirus disease 2019 (COVID‐19) and the rationale for their utilization: A review

Giovane, R., Rezai, S., Cleland, E., & Henderson, C. E. (2020) · Reviews in Medical Virology · doi:10.1002/rmv.2136 · Cited by 16

IVERMECTIN AS ADJUVANT TO HYDROXYCHOLOROQUINE IN PATIENTS RESISTANT TO STANDARD TREATMENT FOR SARS-CoV-2: RESULTS OF AN OPEN-LABEL RANDOMIZED CLINICAL STUDY

Kishoria, N., Mathur, S., Parmar, V., Kaur, R. J., Agarwal, H., Parihar, B. S., & Verma, S. (2020) · PARIPEX-INDIAN JOURNAL OF RESEARCH · doi:10.36106/paripex/4801859 · Cited by 16

The Covid-19 catastrophe: A science communication mess?

León, B., López‐Goñi, I., & Salaverría, R. (2022) · Church Communication and Culture · doi:10.1080/23753234.2022.2031236 · Cited by 15

Integration of transcriptomic profile of SARS-CoV-2 infected normal human bronchial epi-thelial cells with metabolic and protein-protein interaction networks

Karakurt, H. U., & Pir, P. (2020) · TURKISH JOURNAL OF BIOLOGY · doi:10.3906/biy-2005-115 · Cited by 16

A Study on SARS-CoV-2 (COVID-19) and Machine Learning Based Approach to Detect COVID-19 Through X-Ray Images

Gupta, A., Sharma, M., Sharma, A., & Menon, V. (2020) · International Journal of Image and Graphics · doi:10.1142/s0219467821400106 · Cited by 16

Therapeutic options for COVID-19: a quick review

Ismaila, M. S., Bande, F., Ishaka, A., Sani, A. A., & Georges, K. C. (2021) · Journal of Chemotherapy · doi:10.1080/1120009x.2020.1868237 · Cited by 16

ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replicationPreprint

Qu, Y., Wang, X., Zhu, Y., Wang, Y., Yang, X., Hu, G., Liu, C., Li, J., Ren, S., Xiao, Z., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.12.380709 · Cited by 16

THSWD upregulates the LTF/AMPK/mTOR/Becn1 axis and promotes lysosomal autophagy in hepatocellular carcinoma cells by regulating gut flora and metabolic reprogramming

Zhu, Z., Zuo, S., Zhu, Z., Wang, C., Du, Y., & Chen, F. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.114091 · Cited by 15

Hydroxychloroquine as Prophylaxis for Coronavirus SARS-CoV-2 Infection: Review of the Ongoing Clinical Trials

Galvis, V., Spinelli, F. R., Tello, A., Sossa, C., Higuera, J. D., Gómez, E. D., Serrano, S. E., Camacho, P. A., & Velez, F. G. (2020) · Archivos de Bronconeumología · doi:10.1016/j.arbr.2020.05.010 · Cited by 15

Contribution of Nanotechnology in the Fight Against COVID-19

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Hydroxychloroquine as Prophylaxis for COVID-19: A Review

Monti, M., Vertogen, B., Masini, C., Donati, C., Lilli, C., Zingaretti, C., Musuraca, G., Giorgi, U. D., Cerchione, C., Farolfi, A., et al. (2020) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.605185 · Cited by 15

Resistência bacteriana pelo uso indiscriminado da azitromicina frente a Covid-19: uma revisão integrativa

Freires, M. S., & Rodrigues, O. M. (2022) · Research Society and Development · doi:10.33448/rsd-v11i1.25035 · Cited by 15

Panorama mundial de estudos com a hidroxicloroquina para o tratamento da COVID-19

Pacheco, T. J. A., de Souza, D. G., de Lima, L. I., & Longo, J. P. F. (2020) · Journal of Health & Biological Sciences · doi:10.12662/2317-3076jhbs.v8i1.3288.p1-4.2020 · Cited by 15

A fragilidade do sistema de saúde brasileiro e a vulnerabilidade social diante da COVID-19

Silva, M. H. A. D., & Procópio, I. M. (2020) · Revista Brasileira em Promoção da saúde · doi:10.5020/18061230.2020.10724 · Cited by 19

Safety and Efficacy of Amiodarone in a Patient With COVID-19

Castaldo, N., Aimo, A., Castiglione, V., Padalino, C., Emdin, M., & Tascini, C. (2020) · JACC Case Reports · doi:10.1016/j.jaccas.2020.04.053 · Cited by 15

An evidence-based systematic review on emerging therapeutic and preventive strategies to treat novel coronavirus (SARS-CoV-2) during an outbreak scenario

Gudadappanavar, A. M., & Benni, J. M. (2020) · Journal of Basic and Clinical Physiology and Pharmacology · doi:10.1515/jbcpp-2020-0113 · Cited by 16

Drug Repurposing: Dipeptidyl Peptidase IV (DPP4) Inhibitors as Potential Agents to Treat SARS-CoV-2 (2019-nCoV) Infection

Rao, P. P. N., Pham, A. T., Shakeri, A., Shatshat, A. E., Zhao, Y., Karuturi, R. C., & Hefny, A. A. (2021) · Pharmaceuticals · doi:10.3390/ph14010044 · Cited by 15

Pharmacological treatment of COVID-19: Narrative review of the Working Group in Infectious Diseases and Sepsis (GTEIS) and the Working Groups in Transfusions and Blood Products (GTTH)

Dı́az, E., Menéndez, R. A., Cortés, P. V., Escapa, M. G., Suberviola, B., Lázaro, A. S., Marcos-Neira, P., Quintana‐Díaz, M., & González, M. C. (2021) · Medicina Intensiva (English Edition) · doi:10.1016/j.medine.2020.06.007 · Cited by 15

Analogue discovery of safer alternatives to HCQ and CQ drugs for SAR-CoV-2 by computational design

Sinha, M., Gupta, A., Gupta, S., Singh, P., Pandit, S., Chauhan, S. S., & Parthasarathi, R. (2021) · Computers in Biology and Medicine · doi:10.1016/j.compbiomed.2021.104222 · Cited by 15

Hydroxychloroquine with azithromycin in patients hospitalized for mild and moderate COVID-19

Lamback, E. B., de Oliveira, M. A., Haddad, A. F., Vieira, A. F. M., Neto, A. L. F., Maia, T. D. S., Chrisman, J. D. R., Spineti, P. P. D. M., de Mattos, M. A., & Costa, E. (2021) · The Brazilian Journal of Infectious Diseases · doi:10.1016/j.bjid.2021.101549 · Cited by 16

In Vitro and In Silico Studies of Quinoline-2-Carbaldehyde Hydrazone Derivatives as Potent Antimicrobial Agents

Çeli̇k, İ., Erol, M., Püsküllü, M. O., Uzunhisarcıklı, E., İnce, U., Kuyucuklu, G., & Süzen, S. (2020) · Polycyclic aromatic compounds · doi:10.1080/10406638.2020.1821230 · Cited by 15

Astemizole as a drug to inhibit the effect of SARS-COV-2 in vitro

Wang, X., Lu, J., Ge, S., Hou, Y., Hu, T., Lv, Y., Wang, C., & He, H. (2021) · Microbial Pathogenesis · doi:10.1016/j.micpath.2021.104929 · Cited by 16

Characteristics of COVID-19 Clinical Trials in China Based on the Registration Data on ChiCTR and ClinicalTrials.gov

Huang, J., He, Y., Su, Q., & Yang, J. (2020) · Drug Design Development and Therapy · doi:10.2147/dddt.s254354 · Cited by 15

Potential Drug Options for Treatment of COVID-19: A Review

Kebede, T., Kumar, D., & Sharma, P. K. (2020) · Coronaviruses · doi:10.2174/2666796701999200701131604 · Cited by 15

Perspectives on repositioning chloroquine and hydroxychloroquine for the treatment of Covid-19

Adeel, A. (2020) · Sudanese Journal of Paediatrics · doi:10.24911/sjp.106-1587122398 · Cited by 14

Current treatment of COVID-19 in renal patients: hope or hype?

Palumbo, R., Londrino, F., Cordova, E., Gambardella, G., Niscola, P., & Dominijanni, S. (2020) · Internal and Emergency Medicine · doi:10.1007/s11739-020-02510-0 · Cited by 14

Drug-induced liver injury in COVID-19 treatment: Incidence, mechanisms and clinical management

Li, X., Wang, W. “., Yan, S., Zhao, W., Xiong, H., Bao, C., Chen, J., Yue, Y., Su, Y., & Zhang, C. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.1019487 · Cited by 16

COVID-19 and immunomodulation treatment for women with reproductive failures

Kwak-Kim, J. Y.-H., Ota, K., Sung, N., Huang, C., Alsubki, L., Lee, S., Han, J. W., Han, A. R., Yang, X., Saab, W., et al. (2020) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2020.103168 · Cited by 14

Pandemic COVID-19: Current status and challenges of antiviral therapies

Chan, W., He, B., Wang, X., & He, M. (2020) · Genes & Diseases · doi:10.1016/j.gendis.2020.07.001 · Cited by 14

The Public’s Perception of the Severity and Global Impact at the Start of the SARS-CoV-2 Pandemic: A Crowdsourcing-Based Cross-Sectional Analysis

Shauly, O., Stone, G., & Gould, D. J. (2020) · Journal of Medical Internet Research · doi:10.2196/19768 · Cited by 14

Recommendations for prenatal, intrapartum, and postpartum care during COVID‐19 pandemic in India

Sharma, J. B., Sharma, E., Sharma, S., & Singh, J. (2020) · American Journal of Reproductive Immunology · doi:10.1111/aji.13336 · Cited by 14

Can we use hydroxychloroquine to treat COVID-19 now?

Chen, J., Liu, D., Yin, L., Zhang, L., & Lu, H. (2021) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.106173 · Cited by 1

Aminoquinolines against coronavirus disease 2019 (COVID-19): chloroquine or hydroxychloroquine

Sahraei, Z., Shabani, M., Shokouhi, S., & Saffaei, A. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105945 · Cited by 234

Chloroquine and hydroxychloroquine as potential therapies against COVID-19

Yewange, S., Deshpande, R. R., Waghmare, N., Vidyasagar, G., Bavage, S. B., & Bavage, N. B. (2020) · Cited by 1

Chloroquine as a prophylactic agent against COVID-19?

Gendrot, M., Javelle, É., Clerc, A., Savini, H., & Pradines, B. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105980 · Cited by 44

Chloroquine for the 2019 novel coronavirus SARS-CoV-2

Colson, P., Rolain, J., & Raoult, D. (2020) · International Journal of Antimicrobial Agents · doi:10.1016/j.ijantimicag.2020.105923 · Cited by 471