Astragalus Polysaccharide Improves Muscle Atrophy from Dexamethasone- and Peroxide-Induced Injury in Vitro

Akt Promotes Cell Survival by Phosphorylating and Inhibiting a Forkhead Transcription Factor

Brunet, A., Bonni, A., Zigmond, M. J., Lin, M. Z., Juo, P., Hu, L. S., Anderson, M. J., Arden, K. C., Blenis, J., & Greenberg, M. E. (1999) · Cell · doi:10.1016/s0092-8674(00)80595-4 · Cited by 6,535 · see citing works

TOR signaling in growth and metabolism

Wullschleger, S., Loewith, R., & Hall, M. N. (2006) · Cell · doi:10.1016/j.cell.2006.01.016 · Cited by 5,787 · see citing works

Molecular characterization of mitochondrial apoptosis-inducing factor

Susin, S. A., Lorenzo, H. K., Zamzami, N., Marzo, I., Snow, B. E., Brothers, G. M., Mangion, J., Jacotot, E., Costantini, P., Loeffler, M., et al. (1999) · Nature · doi:10.1038/17135 · Cited by 4,060 · see citing works

International Journal of Molecular Medicine

(2026) · International Journal of Molecular Medicine · doi:10.3892/ijmm · Cited by 2,247 · see citing works

The IGF-1/PI3K/Akt pathway prevents expression of muscle atrophy-induced ubiquitin ligases by inhibiting FOXO transcription factors.

Stitt, T. N., Drujan, D., Clarke, B. A., Panaro, F., Timofeyva, Y., Kline, W. O., Gonzalez, M., Yancopoulos, G. D., & Glass, D. J. (2004) · Molecular Cell · doi:10.1016/s1097-2765(04)00211-4 · Cited by 1,964 · see citing works

The activation of Akt/PKB signaling pathway and cell survival

Song, G., Ouyang, G., & Bao, S. (2005) · Journal of Cellular and Molecular Medicine · doi:10.1111/j.1582-4934.2005.tb00337.x · Cited by 1,891 · see citing works

IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

Cai, D., Frantz, J. D., Tawa, N. E., Melendez, P. A., Oh, B.-C., Lidov, H. G. W., Hasselgren, P.-O., Frontera, W. R., Lee, J., Glass, D. J., et al. (2004) · Cell · doi:10.1016/j.cell.2004.09.027 · Cited by 1,367 · see citing works

4 Histology and Histopathology

(2015) · Thieme eBooks · doi:10.1055/b-0035-108581 · Cited by 1,052 · see citing works

Dysregulation of the TSC-mTOR pathway in human disease

Inoki, K., Corradetti, M. N., & Guan, K. (2004) · Nature Genetics · doi:10.1038/ng1494 · Cited by 970 · see citing works

Reactive Oxygen Species and Reactive Nitrogen Species in Peroxisomes. Production, Scavenging, and Role in Cell Signaling

del Río, L. A., Sandalio, L. M., Corpas, F. J., Palma, J. M., & Barroso, J. B. (2006) · PLANT PHYSIOLOGY · doi:10.1104/pp.106.078204 · Cited by 635 · see citing works

Smad2 and 3 transcription factors control muscle mass in adulthood

Sartori, R., Milan, G., Patron, M., Mammucari, C., Blaauw, B., Abraham, R., & Sandri, M. (2009) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00104.2009 · Cited by 517 · see citing works

Insulin-like Growth Factor-1 (IGF-1) Inversely Regulates Atrophy-induced Genes via the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Pathway*

Latres, E., Amini, A. R., Amini, A. A., Griffiths, J. S., Martin, F. J., Wei, Y., Lin, H. C., Yancopouloš, G., & Glass, D. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m407517200 · Cited by 514 · see citing works

Anticancer therapy targeting the apoptotic pathway

Hu, W., & Kavanagh, J. J. (2003) · The Lancet Oncology · doi:10.1016/s1470-2045(03)01277-4 · Cited by 511 · see citing works

Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training

Lenk, K., Schuler, G. C., & Adams, V. (2010) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1007/s13539-010-0007-1 · Cited by 492 · see citing works

Molecular mechanisms modulating muscle mass

Glass, D. J. (2003) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(03)00138-2 · Cited by 442 · see citing works

Cell-autonomous regulation of cell and organ growth in Drosophila by Akt/PKB

Verdú, J., Buratovich, M., Wilder, E., & Birnbaum, M. (1999) · Nature Cell Biology · doi:10.1038/70293 · Cited by 397 · see citing works

Denervation-Induced Skeletal Muscle Atrophy Is Associated with Increased Mitochondrial Ros Production

Muller, F. L., Song, W., Jang, Y. C., Liu, Y., Sabia, M., Richardson, A., & Van Remmen, H. (2007) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00767.2006 · Cited by 355 · see citing works

Regulation of imaginal disc cell size, cell number and organ size by Drosophila class IA phosphoinositide 3-kinase and its adaptor

Weinkove, D., Neufeld, T. P., Twardzik, T., Waterfield, M. D., & Leevers, S. J. (1999) · Current Biology · doi:10.1016/s0960-9822(99)80450-3 · Cited by 293 · see citing works

The conserved PI3′K/PTEN/Akt signaling pathway regulates both cell size and survival in Drosophila

Scanga, S. E., Ruel, L., Binari, R. C., Snow, B., Stambolic, V., Bouchard, D., Peters, M., Calvieri, B., Mak, T. W., Woodgett, J. R., et al. (2000) · Oncogene · doi:10.1038/sj.onc.1203739 · Cited by 195 · see citing works

The role of systemic inflammation in age‐related muscle weakness and wasting

Degens, H. (2009) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/j.1600-0838.2009.01018.x · Cited by 188 · see citing works

Dexamethasone and corticosterone induce similar, but not identical, muscle wasting responses in cultured L6 and C2C12 myotubes

Menconi, M. J., GONNELLA, P. A., Petkova, V., Lecker, S. H., & Hasselgren, P.-O. J. (2008) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21833 · Cited by 183 · see citing works

The muscle satellite cell at 50: the formative years

Scharner, J., & Zammit, P. S. (2011) · Skeletal Muscle · doi:10.1186/2044-5040-1-28 · Cited by 180 · see citing works

Doxorubicin acts via mitochondrial ROS to stimulate catabolism in C2C12 myotubes

Gilliam, L. A. A., Moylan, J. S., Patterson, E. W., Smith, J. D., Wilson, A. S., Rabbani, Z., & Reid, M. B. (2011) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00217.2011 · Cited by 162 · see citing works

Astragalus polysaccharide improves insulin sensitivity in KKAy mice: Regulation of PKB/GLUT4 signaling in skeletal muscle

Liu, M., Wu, K., Mao, X., Wu, Y., & Ouyang, J. (2009) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2009.09.055 · Cited by 158 · see citing works

FOXO3a mediates signaling crosstalk that coordinates ubiquitin and atrogin-1/MAFbx expression during glucocorticoid-induced skeletal muscle atrophy

Zheng, B., Ohkawa, S., Li, H., Roberts‐Wilson, T. K., & Price, S. R. (2010) · The FASEB Journal · doi:10.1096/fj.09-151480 · Cited by 145 · see citing works

NF-κB mediates proteolysis-inducing factor induced protein degradation and expression of the ubiquitin–proteasome system in skeletal muscle

Wyke, S. M., & Tisdale, M. J. (2005) · British Journal of Cancer · doi:10.1038/sj.bjc.6602402 · Cited by 130 · see citing works

Role of oxidative stress and apoptosis in cadmium induced thymic atrophy and splenomegaly in mice

Pathak, N., & Khandelwal, S. (2007) · Toxicology Letters · doi:10.1016/j.toxlet.2006.12.009 · Cited by 123 · see citing works

Role of glucocorticoids in the molecular regulation of muscle wasting

Menconi, M. J., Fareed, M. U., O’Neal, P., Poylin, V. Y., Wei, W., & Hasselgren, P. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000279194.11328.77 · Cited by 115 · see citing works

Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism

Liao, X., Majithia, A. R., Huang, X., & Kimmel, A. R. (2008) · Amino Acids · doi:10.1007/s00726-008-0100-3 · Cited by 110 · see citing works

Skeletal muscle atrophy is associated with an increased expression of myostatin and impaired satellite cell function in the portacaval anastamosis rat

Dasarathy, S., Dodig, M., Muc, S., Kalhan, S. C., & McCullough, A. J. (2004) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.00202.2004 · Cited by 107 · see citing works

Hypoglycemic effect of Astragalus polysaccharide and its effect on PTP1B1

Wu, Y., Ouyang, J., Wu, K., Wang, Y., Zhou, Y., & Wen, C.-Y. (2005) · Acta Pharmacologica Sinica · doi:10.1111/j.1745-7254.2005.00062.x · Cited by 101 · see citing works

Therapeutic effects of astragalus polysaccharides on inflammation and synovial apoptosis in rats with adjuvant‐induced arthritis

Jiang, J., Jian‐Dong, Q. I. U., Li‐Hua, Y. A. N. G., He, J., Smith, G. W., & Li, H. (2010) · International Journal of Rheumatic Diseases · doi:10.1111/j.1756-185x.2010.01555.x · Cited by 97 · see citing works

Multipolar functions of BCL-2 proteins link energetics to apoptosis

Hardwick, J. M., Chen, Y., & Jonas, E. A. (2012) · Trends in Cell Biology · doi:10.1016/j.tcb.2012.03.005 · Cited by 94 · see citing works

Death receptor signaling regulatory function for telomerase: hTERT abolishes TRAIL-induced apoptosis, independently of telomere maintenance

Dudognon, C., Pendino, F., Hillion, J., Saumet, A., Lanotte, M., & Ségal-Bendirdjian, E. (2004) · Oncogene · doi:10.1038/sj.onc.1208029 · Cited by 84 · see citing works

Merit of Astragalus polysaccharide in the improvement of early diabetic nephropathy with an effect on mRNA expressions of NF-κB and IκB in renal cortex of streptozotoxin-induced diabetic rats

Zhang, Y., Wu, C., & Cheng, J. (2007) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2007.08.024 · Cited by 84 · see citing works

Immunoregulatory and Anti-Tumor Effects of Polysaccharopeptide and Astragalus polysaccharides on Tumor-Bearing Mice

Jin, L., Yixi, B., Wai-kei, L., Li, W., Lu, F. Y., Zhu, X., Jing, L., & Hongping, W. (2008) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923970802279183 · Cited by 82 · see citing works

Molecular Weight and Monosaccharide Composition of Astragalus Polysaccharides

Xu, D., Xia, Q., Wang, J., & Wang, P.-P. (2008) · Molecules · doi:10.3390/molecules13102408 · Cited by 78 · see citing works

Role of Akt/GSK-3β/β-Catenin Transduction Pathway in the Muscle Anti-Atrophy Action of Insulin-Like Growth Factor-I in Glucocorticoid-Treated Rats

Schakman, O., Kalista, S., Bertrand, L., Lause, P., Verniers, J., Ketelslegers, J. M., & Thissen, J. (2008) · Endocrinology · doi:10.1210/en.2008-0439 · Cited by 78 · see citing works

Protection against Glucocorticoid-Induced Damage in Human Tenocytes by Modulation of ERK, Akt, and Forkhead Signaling

Poulsen, R. C., Carr, A. J., & Hulley, P. A. (2011) · Endocrinology · doi:10.1210/en.2010-1087 · Cited by 77 · see citing works

Alternative Effects of the Ubiquitin-Proteasome Pathway on Glucocorticoid Receptor Down-Regulation and Transactivation Are Mediated by CHIP, an E3 Ligase

Wang, X., & DeFranco, D. B. (2005) · Molecular Endocrinology · doi:10.1210/me.2004-0383 · Cited by 77 · see citing works

Hyrtiosal, a PTP1B Inhibitor from the Marine Sponge Hyrtios erectus, Shows Extensive Cellular Effects on PI3K/AKT Activation, Glucose Transport, and TGFβ/Smad2 Signaling

Sun, T., Wang, Q., Yu, Z., Zhang, Y., Guo, Y., Chen, K., Shen, X., & Jiang, H. (2006) · ChemBioChem · doi:10.1002/cbic.200600349 · Cited by 54 · see citing works

Therapeutic targeting of signaling pathways in muscular dystrophy

Bhatnagar, S., & Kumar, A. (2009) · Journal of Molecular Medicine · doi:10.1007/s00109-009-0550-4 · Cited by 52 · see citing works

Astragalus saponins modulate mTOR and ERK signaling to promote apoptosis through the extrinsic pathway in HT-29 colon cancer cells

Ko, J. K.-S. (2010) · International Journal of Molecular Medicine · doi:10.3892/ijmm_00000471 · Cited by 48 · see citing works

C2C12 myoblast sensitivity to different apoptotic chemical triggers

Salucci, S., Battistelli, M., Burattini, S., Squillace, C., Canonico, B., Gobbi, P., Papa, S., & Falcieri, E. (2010) · Micron · doi:10.1016/j.micron.2010.07.002 · Cited by 42 · see citing works

Role of the ubiquitin-proteasome pathway in sepsis-induced muscle catabolism

Hasselgren, P. (1999) · Molecular Biology Reports · doi:10.1023/a:1006916206260 · Cited by 39 · see citing works

Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts

Soltow, Q. A., Lira, V. A., Betters, J. L., Long, J. H. D., Sellman, J. E., Zeanah, E. H., & Criswell, D. S. (2010) · Journal of Muscle Research and Cell Motility · doi:10.1007/s10974-010-9227-4 · Cited by 37 · see citing works

Morphological and biochemical patterns in skeletal muscle apoptosis.

D'Emilio, A., Biagiotti, L., Burattini, S., Battistelli, M., Canonico, B., Evangelisti, C., Ferri, P., Papa, S., Martelli, A. M., & Falcieri, E. (2010) · PubMed · doi:10.14670/hh-25.21 · Cited by 36 · see citing works

Effects of Astragalus polysaccharide on the erythroid lineage and microarray analysis in K562 cells

Yang, M., Qian, X.-H., Zhao, D., & Fu, S.-Z. (2009) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2009.11.013 · Cited by 35 · see citing works

Is there a common mechanism linking muscle wasting in various disease types?

Tisdale, M. J. (2007) · Current Opinion in Supportive and Palliative Care · doi:10.1097/spc.0b013e3282f35238 · Cited by 30 · see citing works

Effects of Astragalus polysaccharide on proliferation and Akt phosphorylation of the basal-like breast cancer cell line

Ye, M. (2011) · Journal of Chinese Integrative Medicine · doi:10.3736/jcim20111210 · Cited by 21 · see citing works

Roles and potential therapeutic targets of the ubiquitin proteasome system in muscle wasting

Nury, D., Doucet, C. M., & Coux, O. (2007) · BMC Biochemistry · doi:10.1186/1471-2091-8-s1-s7 · Cited by 21 · see citing works

Chronic ethanol consumption up-regulates protein-tyrosine phosphatase-1B (PTP1B) expression in rat skeletal muscle

Gao, L., Zhang, X., Wang, F., Cao, M., Zhang, X., Sun, N., Zhang, J., Gao, L., & Zhao, J. (2010) · Acta Pharmacologica Sinica · doi:10.1038/aps.2010.161 · Cited by 18 · see citing works

Steroid effects on ZAP-70 and SYK in relation to apoptosis in poor prognosis chronic lymphocytic leukemia

Boelens, J., Lust, S., Bockstaele, F. V., Gele, M. V., Janssens, A. M., Derycke, L., Vanhoecke, B. W. A., Philippé, J., Bracke, M., & Offner, F. C. (2009) · Leukemia Research · doi:10.1016/j.leukres.2009.02.022 · Cited by 15 · see citing works

Cell Cycle Arrest Effects of Large-Dose FTY720 on Lymphocytes in Mouse Skin Transplantation Models

Li, Q. Y., Chi, Y. Y., & Liu, S. (2008) · Immunopharmacology and Immunotoxicology · doi:10.1080/08923970801949174 · Cited by 12 · see citing works

Advances on Bioactive Polysaccharides from Medicinal Plants

Xie, J., Jin, M.-L., Morris, G. A., Zha, X., Chen, H.-Q., Yi, Y., Li, J.-E., Wang, Z.-J., Gao, J., Nie, S., et al. (2015) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2015.1069255 · Cited by 568 · see citing works

Characteristics of traditional Chinese medicine usage in patients with stroke in Taiwan: A nationwide population-based study

Chang, C., Lee, Y., Lin, C., Chang, C.-H., Chiu, C., Chou, L., Sun, M.-F., & Yen, H. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.04.018 · Cited by 81 · see citing works

Single-cell transcriptomic analyses of cardiac immune cells reveal that Rel-driven CD72-positive macrophages induce cardiomyocyte injury

Ni, S.-H., Xu, J., Sun, S., Li, Y., Zhou, Z., Li, H., Liu, X., Deng, J., Huang, Y., Chen, Z., et al. (2021) · Cardiovascular Research · doi:10.1093/cvr/cvab193 · Cited by 68 · see citing works

Effects of Astragalus Polysaccharides on Dysfunction of Mitochondrial Dynamics Induced by Oxidative Stress

Huang, Y., Lu, L., Zhu, D., Wang, M., Yin, Y., Chen, D., & Wei, L. (2016) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2016/9573291 · Cited by 67 · see citing works

Nutraceuticals in the Prevention and Treatment of the Muscle Atrophy

Wang, Y., Liu, Q., Quan, H., Kang, S.-G., Huang, K., & Tong, T. (2021) · Nutrients · doi:10.3390/nu13061914 · Cited by 61 · see citing works

Astragalus polysaccharide ameliorates H2O2-induced human umbilical vein endothelial cell injury

Han, R., Tang, F., Lü, M., Xu, C., Hu, J., Mei, M., & Wang, H. (2017) · Molecular Medicine Reports · doi:10.3892/mmr.2017.6515 · Cited by 58 · see citing works

Astragalus polysaccharides decrease muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling in 5/6 nephrectomised rats

Lu, L., Huang, Y., Chen, D., Wang, M., Zou, Y., Wan, H., & Wei, L. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.03.068 · Cited by 48 · see citing works

Study on semi-bionic extraction of Astragalus polysaccharide and its anti-aging activity in vivo

Yan, X., Miao, J., Zhang, B., Liu, H., Ma, H., Sun, Y., Liu, P., Zhang, X., Wang, R., Kan, J., et al. (2023) · Frontiers in Nutrition · doi:10.3389/fnut.2023.1201919 · Cited by 36 · see citing works

Properties and characterization of thyme essential oil incorporated collagen hydrolysate films extracted from hide fleshing wastes for active packaging

Ocak, B. (2020) · Environmental Science and Pollution Research · doi:10.1007/s11356-020-09259-1 · Cited by 35 · see citing works

Lobetyolin Alleviates Ferroptosis of Skeletal Muscle in 5/6 Nephrectomized Mice via Activation of Hedgehog-GLI1 Signaling

Ni, S.-H., Zhang, X., Ou-Yang, X.-L., Ye, T., Li, J., Li, Y., Sun, S., Han, X.-W., Long, W.-J., Wang, L., et al. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154807 · Cited by 33 · see citing works

The regulatory role of dietary factors in skeletal muscle development, regeneration and function

Wang, L., Xu, Z., Ling, D., Li, J., Wang, Y., & Shan, T. (2020) · Critical Reviews in Food Science and Nutrition · doi:10.1080/10408398.2020.1828812 · Cited by 33 · see citing works

Astragalus Polysaccharide Inhibits Autophagy and Apoptosis from Peroxide-Induced Injury in C2C12 Myoblasts

Yin, Y., Lu, L., Wang, D., Shi, Y. Q., Wang, M., Huang, Y., Chen, D., Deng, C., Chen, J., Lv, P.-J., et al. (2015) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-015-0659-8 · Cited by 27 · see citing works

Promotion of chronic wound healing by plant-derived active ingredients and research progress and potential of plant polysaccharide hydrogels

Yan, R., Wang, Y., Li, W., & Sun, J. (2024) · Chinese Herbal Medicines · doi:10.1016/j.chmed.2024.11.005 · Cited by 26 · see citing works

Astragalus membranaceus Enhances Myotube Hypertrophy through PI3K-Mediated Akt/mTOR Signaling Phosphorylation

Yeh, T., Lei, T., Liu, J., & Hsu, M. (2022) · Nutrients · doi:10.3390/nu14081670 · Cited by 21 · see citing works

Hispaglabridin B, a constituent of liquorice identified by a bioinformatics and machine learning approach, relieves protein‐energy wasting by inhibiting forkhead box O1

Huang, Z., Wang, L., Wang, J., Feng, W., Yang, Z., Ni, S.-H., Huang, Y., Li, H., Yang, Y., Wang, M., et al. (2018) · British Journal of Pharmacology · doi:10.1111/bph.14508 · Cited by 18 · see citing works

Astragalus polysaccharide promotes sheep satellite cell differentiation by regulating miR-133a through the MAPK/ERK signaling pathway

Su, Y., Gao, X., Wang, Y., Li, X., Zhang, W., & Zhao, J. (2023) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2023.124351 · Cited by 16 · see citing works

A Review of Complementary and Alternative Medicine Therapies on Muscular Atrophy: A Literature Review of In Vivo/In Vitro Studies

Jeong, S.-M., Seo, B.-K., Park, Y., & Baek, Y.-H. (2018) · Evidence-based Complementary and Alternative Medicine · doi:10.1155/2018/8654719 · Cited by 12 · see citing works

Structural features of galacturonic acid-rich polysaccharides from Ziziphus jujuba and their protective effects against insulin resistance and muscle atrophy

Ko, K., Guo, C., Kim, E., Zhang, G., & Lee, Y. (2025) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2025.146287 · Cited by 7 · see citing works

A Systematic Review and User Reference of Phenotypic and Molecular Characteristics of Dexamethasone‐Mediated C2C12 Muscle Atrophy

Klein, A. J., & Vaughan, R. A. (2026) · Journal of Cachexia Sarcopenia and Muscle · doi:10.1002/jcsm.70127 · Cited by 5 · see citing works

FGF‐Mimicking Triphen[3]arene Peptide Self‐Assembly to Accelerate Muscle Regeneration and Repair

Ding, J., Wang, Z., Lu, J., Feng, Y., Wang, J., Zhu, Q., Wu, J., Shang, Y., Kuang, M., & Li, C. (2024) · Advanced Functional Materials · doi:10.1002/adfm.202408511 · Cited by 5 · see citing works

Effects of Astragalus polysaccharide supplementation on growth performance, carcass quality, muscle fiber characteristics, meat quality, and development of finishing pigs

Ma, W., Ma, Z., Zhang, X., Mao, P., Gao, M., Zhao, L., & Wu, Q. (2025) · Frontiers in Nutrition · doi:10.3389/fnut.2025.1654720 · Cited by 4 · see citing works

The Protective Effects of Dangguibohyul-tang (Dangguibuxuetang) against Disuse Muscle Atrophy in Rats

Kim, B. H. (2017) · Journal of Korean Medicine Rehabilitation · doi:10.18325/jkmr.2017.27.4.1 · Cited by 4 · see citing works

Anemarrhena asphodeloides fructan attenuates cigarette smoke-induced muscle atrophy by activating the Akt/mTOR pathway and inhibiting the ubiquitin-proteasome pathway

Wang, L., Pan, Y., Lin, B., Zhang, F., Xu, L., Huang, F., & Wang, N. (2025) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2025.120116 · Cited by 2 · see citing works

Astragalus polysaccharide mediates lnc-GD2H to regulate proliferation and differentiation of C2C12 muscle cells under hypoxic condition

Liang, W., Yang, L., Lei, S., Chen, R., Shi, H., Li, F., Liao, Z., Zhong, C., & She, Y. (2025) · Tissue and Cell · doi:10.1016/j.tice.2025.102731 · Cited by 2 · see citing works

Astragalus Polysaccharide Alleviates COPD‐Associated Skeletal Muscle Dysfunction Through Suppression of Inflammation and Cellular Senescence

Mou, Y., Liu, Y., Chen, Y., Shen, R., Yan, A., Liao, T., Liu, Y., Su, H., He, Z., Wang, Y., et al. (2025) · Food Frontiers · doi:10.1002/fft2.70088 · Cited by 2 · see citing works

Astragalus polysaccharide enhances OGT-mediated O-GlcNAcylation to stabilize PINK1 to induce mitophagy in D-galactose treated C2C12 myoblasts

Chen, D., Qiu, Z., Wu, Y., Zhang, Y., Huang, H., Yang, H., & Xiao, Q. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115617 · Cited by 1 · see citing works

PDMD: A Comprehensive Repository of Plants Reported for Skeletal Muscle-related Ailments

Gupta, A., & Chawla, S. (2026) · Current Drug Targets · doi:10.2174/0113894501435270251129220150 · Cited by 1 · see citing works

Efficacy and safety of medicine-food homology Shenqi paste in older adults with diabetic sarcopenia: A randomized, double-blind, placebo-controlled trial

Hua, L., Wang, Y., Yuan, X., Wang, R., Li, X., Fan, Y., Hou, Z., Yang, L., Liu, T., & Sun, Q. (2026) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2026.121444 · Cited by 1 · see citing works

Astragalus polysaccharides alleviate oxidative damage by activating the Keap1-Nrf2 antioxidant pathway through miR-183-5p in a fish cell model

Wang, Y., An, H., Ma, F., Xia, D., Weng, Z., Chen, X., & Zhang, W. (2026) · Fish & Shellfish Immunology · doi:10.1016/j.fsi.2026.111548 · Cited by 1 · see citing works

Effect of Bioprocessed Black Rice Bran on Muscle Strength in a Dexamethasone-Induced Muscle Atrophy C2C12 Model

Song, T.-W., Cho, G.-H., Ko, D.-H., Song, A., Kim, S. P., Lee, O., & Choi, S. (2025) · Journal of the Korean Society of Food Science and Nutrition · doi:10.3746/jkfn.2025.54.2.140

Astragalus membranaceus extract for sports-related hamstring injuries: A therapeutic analysis with MRI

Song, Z. (2025) · Journal of Radiation Research and Applied Sciences · doi:10.1016/j.jrras.2025.101905

Protective effects of Astragalus membranaceus polysaccharide against aluminum oxide nanoparticle-induced growth retardation and oxidative-immunological disruption in Oreochromis niloticus

Megeed, O. H. A. E., Rashad, M. M., Ali, G. E., Ragab, E., Elmaghraby, I., Youssef, F. S., & Mahmoud, S. B. (2026) · Scientific Reports · doi:10.1038/s41598-026-46411-2

Astragalus Polysaccharide Activates the AKT-mTOR Pathway to Reduce ROS and Promote Intramuscular Protein Levels in Sarcopenia Mice

Xu, J., Zhang, X., Li, K., & Wan, R. (2025) · Pharmacognosy Magazine · doi:10.1177/09731296251367539

Astragalus Polysaccharide Inhibits Autophagy and Apoptosis from Peroxide-Induced Injury in C2C12 Myoblasts

Yin, Y., Lu, L., Wang, D., Shi, Y. Q., Wang, M., Huang, Y., Chen, D., Deng, C., Chen, J., Lv, P.-J., et al. (2015) · Cell Biochemistry and Biophysics · doi:10.1007/s12013-015-0659-8 · Cited by 27 · see citing works

Astragalus polysaccharides decrease muscle wasting through Akt/mTOR, ubiquitin proteasome and autophagy signalling in 5/6 nephrectomised rats

Lu, L., Huang, Y., Chen, D., Wang, M., Zou, Y., Wan, H., & Wei, L. (2016) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2016.03.068 · Cited by 48 · see citing works

Astragalus polysaccharide enhances OGT-mediated O-GlcNAcylation to stabilize PINK1 to induce mitophagy in D-galactose treated C2C12 myoblasts

Chen, D., Qiu, Z., Wu, Y., Zhang, Y., Huang, H., Yang, H., & Xiao, Q. (2025) · International Immunopharmacology · doi:10.1016/j.intimp.2025.115617 · Cited by 1 · see citing works

Astragalus Polysaccharide Alleviates COPD‐Associated Skeletal Muscle Dysfunction Through Suppression of Inflammation and Cellular Senescence

Mou, Y., Liu, Y., Chen, Y., Shen, R., Yan, A., Liao, T., Liu, Y., Su, H., He, Z., Wang, Y., et al. (2025) · Food Frontiers · doi:10.1002/fft2.70088 · Cited by 2 · see citing works