Synthesis, Drying Process and Medical Application of Polysaccharide-Based Aerogels
Abstract
Aerogels are promisingly intended for the use in describing lighter solid materials with huge porous structures. The outcome of aerogels is of potential interest in biomedical purposes owing to many features such as high surface area, low density and porous structure, and so forth. There are numerous inorganic and organic materials employed in the preparation of aerogels. Many drying techniques are a fundamental part of their preparation such as supercritical, freeze-drying, vacuum, ambient pressure and microwave which have been utilized for drying the wet-gel via substitute the liquid inside the wet-gel pores with air. Three common lighter solid materials (i.e. aerogel, cryogel and xerogel) could be synthesized depending on the drying technique applied. This review focuses on aerogel definition, the steps for the preparation of aerogel, techniques used for drying the wet-gel platforms. Further it highlights the pros and cons of each drying technique for synthesizing a demanded material's properties. As polysaccharide considered as one of the most prominent biocompatible and environmentally friendly polymers used for their preparation, thus we will present some examples (e.g.; cellulose, chitosan, starch, alginate, carrageenan and curdlan) and finally the potential biomedical applications of polysaccharides-based aerogel are briefly emphasized.
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Freeze-drying is a straightforward, affordable, and environmentally benign process for producing porous materials, though it can occasionally take longer than supercritical drying.
“The production of porous materials can also be achieved via the straightforward, affordable, and environmentally benign process of freeze-drying, which can occasionally take longer than supercritical drying [38].”
From Silica Aerogels as a Promising Vehicle for Effective Water Splitting for Hydrogen Production (2025) · cites this paper as [38]
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References 120 · Cited by 197
- Authors
- El-Naggar, M. E., Othman, S. I., Allam, A. A., & Morsy, O. M.
- Affiliations
- Princess Nourah bint Abdulrahman University (SA)
- Beni-Suef University (EG)
- Arab Academy for Science, Technology, and Maritime Transport (EG)
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2020-02
- Volume
- 145
- Pages
- 1115-1128
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W2982597677
- Cited by
- 197
- References
- 120
- Citations by year
- 2026: 17 · 2025: 27 · 2024: 45 · 2023: 30 · 2022: 23 · 2021: 31 · 2020: 22 · 2019: 2
- FWCI
- 1.99
- Type
- journal article
- Language
- en
- Update notices
- erratum (2021-03-01)
- Open access
- closed
- Locations
- International Journal of Biological Macromolecules (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Chemistry › Spectroscopy › Aerogels and thermal insulation
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Keywords
- polysaccharide aerogels, aerogel synthesis, drying methods, supercritical drying, freeze-drying, microwave drying, cryogels, xerogels, chitosan, cellulose, starch, alginate, carrageenan, curdlan, biomedical applications, porous media
- MeSH terms
- Alginates, Carrageenan, Cellulose, Desiccation, Freeze Drying, Gels, Pectins, Polysaccharides, Starch, Porosity, Drug Delivery Systems, Biomedical Technology, Tissue Engineering, beta-Glucans, Chitosan, Cryogels
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