Cited by 197Aerogels and thermal insulationHydrogels: synthesis, properties, applicationsPolysaccharides Composition and Applications

Synthesis, Drying Process and Medical Application of Polysaccharide-Based Aerogels

El-Naggar, Mehrez E., Othman, Sarah I., Allam, Ahmed A., Morsy, Osama M.·2020·International Journal of Biological Macromolecules

Abstract

Aerogels are promisingly intended for the use in describing lighter solid materials with huge porous structures. The outcome of aerogels is of potential interest in biomedical purposes owing to many features such as high surface area, low density and porous structure, and so forth. There are numerous inorganic and organic materials employed in the preparation of aerogels. Many drying techniques are a fundamental part of their preparation such as supercritical, freeze-drying, vacuum, ambient pressure and microwave which have been utilized for drying the wet-gel via substitute the liquid inside the wet-gel pores with air. Three common lighter solid materials (i.e. aerogel, cryogel and xerogel) could be synthesized depending on the drying technique applied. This review focuses on aerogel definition, the steps for the preparation of aerogel, techniques used for drying the wet-gel platforms. Further it highlights the pros and cons of each drying technique for synthesizing a demanded material's properties. As polysaccharide considered as one of the most prominent biocompatible and environmentally friendly polymers used for their preparation, thus we will present some examples (e.g.; cellulose, chitosan, starch, alginate, carrageenan and curdlan) and finally the potential biomedical applications of polysaccharides-based aerogel are briefly emphasized.

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Crossref · 10.1016/j.ijbiomac.2019.10.037

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  • Freeze-drying is a straightforward, affordable, and environmentally benign process for producing porous materials, though it can occasionally take longer than supercritical drying.

    “The production of porous materials can also be achieved via the straightforward, affordable, and environmentally benign process of freeze-drying, which can occasionally take longer than supercritical drying [38].”

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References 120 · Cited by 197

Authors
El-Naggar, M. E., Othman, S. I., Allam, A. A., & Morsy, O. M.
Affiliations
  • Princess Nourah bint Abdulrahman University (SA)
  • Beni-Suef University (EG)
  • Arab Academy for Science, Technology, and Maritime Transport (EG)
Venue
International Journal of Biological Macromolecules
Publisher
Elsevier BV
Published
2020-02
Volume
145
Pages
1115-1128
ISSN
0141-8130 (ISSN-L)
OpenAlex
W2982597677
Cited by
197
References
120
Citations by year
2026: 17 · 2025: 27 · 2024: 45 · 2023: 30 · 2022: 23 · 2021: 31 · 2020: 22 · 2019: 2
FWCI
1.99
Type
journal article
Language
en
Update notices
erratum (2021-03-01)
Open access
closed
Locations
  • International Journal of Biological Macromolecules (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Physical Sciences › Chemistry › Spectroscopy › Aerogels and thermal insulation
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Medicine › Hydrogels: synthesis, properties, applications
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
Keywords
polysaccharide aerogels, aerogel synthesis, drying methods, supercritical drying, freeze-drying, microwave drying, cryogels, xerogels, chitosan, cellulose, starch, alginate, carrageenan, curdlan, biomedical applications, porous media
MeSH terms
Alginates, Carrageenan, Cellulose, Desiccation, Freeze Drying, Gels, Pectins, Polysaccharides, Starch, Porosity, Drug Delivery Systems, Biomedical Technology, Tissue Engineering, beta-Glucans, Chitosan, Cryogels

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