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Cited by 266

The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.

Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing

Pan, Wenhao, Qi, Xiaoliang, Xiang, Yajing, You, Shengye, Cai, Erya, Gao, Teng, Tong, Xianqin, Hu, Rongdang, Shen, Jianliang, Deng, Hui·2022·International Journal of Biological Macromolecules

Abstract

The wound healing process of the diabetic wound is often hindered by excessive oxygen free radicals and infection. An ideal wound dressing should possess great reactive oxygen species (ROS) scavenging property and considerable antibacterial ability. In this study, we facilely constructed a novel hydrogel dressing with excellent ROS scavenging property and outstanding antibacterial performance by introducing tannic acid (TA) into quaternized chitosan (QCS) matrix. Attributing to the suitable physical crosslinking between TA and QCS, this QCS/TA hydrogel was endowed with injectable and self-healing properties, which could avoid the various external squeezing on the irregular shape by wound dressing. The results showed that it could promote coagulation, suppress inflammation and expedite collagen deposition in the skin defect model of diabetic rats. This study provides a facile and convenient method for constructing injectable hydrogel dressing, which has application potentials in the clinical management of diabetic wounds.

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Crossref · 10.1016/j.ijbiomac.2021.12.007

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Metadata

Authors
Pan, W., Qi, X., Xiang, Y., You, S., Cai, E., Gao, T., Tong, X., Hu, R., Shen, J., & Deng, H.
Venue
International Journal of Biological Macromolecules
Publisher
Elsevier BV
Published
2022-01
Volume
195
Pages
190-197
ISSN
0141-8130 (ISSN-L)
OpenAlex
W4200153950
Cited by
266
References
45
FWCI
19.89
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing. https://app.cochat.ai/papers/10.1016/j.ijbiomac.2021.12.007
The paper
Pan, W., Qi, X., Xiang, Y., You, S., Cai, E., Gao, T., Tong, X., Hu, R., Shen, J., & Deng, H. (2022). Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2021.12.007

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.