The DOI matches its Crossref record; 45 of the 45 references it cites were found in a registry or an index.
Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing
Abstract
The wound healing process of the diabetic wound is often hindered by excessive oxygen free radicals and infection. An ideal wound dressing should possess great reactive oxygen species (ROS) scavenging property and considerable antibacterial ability. In this study, we facilely constructed a novel hydrogel dressing with excellent ROS scavenging property and outstanding antibacterial performance by introducing tannic acid (TA) into quaternized chitosan (QCS) matrix. Attributing to the suitable physical crosslinking between TA and QCS, this QCS/TA hydrogel was endowed with injectable and self-healing properties, which could avoid the various external squeezing on the irregular shape by wound dressing. The results showed that it could promote coagulation, suppress inflammation and expedite collagen deposition in the skin defect model of diabetic rats. This study provides a facile and convenient method for constructing injectable hydrogel dressing, which has application potentials in the clinical management of diabetic wounds.
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1 retracted
Tong, X., Qi, X., Mao, R., Pan, W., Zhang, M., Wu, X., Chen, G., Shen, J., Deng, H., & Hu, R. (2020) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2020.116585 · Cited by 75
Self-citationRetractedDunnill, C., Patton, T., Brennan, J., Barrett, J., Dryden, M., Cooke, J., Leaper, D., & Georgopoulos, N. T. (2017) · International Wound Journal · doi:10.1111/iwj.12557 · Cited by 1,380
Zhao, X., Liang, Y., Huang, Y., He, J., Han, Y., & Guo, B. (2020) · Advanced Functional Materials · doi:10.1002/adfm.201910748 · Cited by 814
Rational Design of Immunomodulatory Hydrogels for Chronic Wound Healing
Kharaziha, M., Baidya, A., & Annabi, N. (2021) · Advanced Materials · doi:10.1002/adma.202100176 · Cited by 721
Li, M., Liang, Y., He, J., Zhang, H., & Guo, B. (2020) · Chemistry of Materials · doi:10.1021/acs.chemmater.0c02823 · Cited by 479
Qu, B., & Luo, Y. (2020) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.02.240 · Cited by 446
Ahmadian, Z., Correia, A., Hasany, M., Figueiredo, P., Dobakhti, F., Eskandari, M. R., Hosseini, S. H., Abiri, R., Khorshid, S., Hirvonen, J., et al. (2021) · Advanced Healthcare Materials · doi:10.1002/adhm.202001122 · Cited by 351
Recent advances in natural polymer-based drug delivery systems
Tong, X., Pan, W., Su, T., Zhang, M., Dong, W., & Qi, X. (2020) · Reactive and Functional Polymers · doi:10.1016/j.reactfunctpolym.2020.104501 · Cited by 349
Self-citationRecent advances in dextran-based drug delivery systems: From fabrication strategies to applications
Hu, Q., Lu, Y., & Luo, Y. (2021) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2021.117999 · Cited by 315
Multifunctional hydrogels for wound healing: Special focus on biomacromolecular based hydrogels
Asadi, N., Pazoki-Toroudi, H., Del Bakhshayesh, A. R., Akbarzadeh, A., Davaran, S., & Annabi, N. (2021) · International Journal of Biological Macromolecules · doi:10.1016/j.ijbiomac.2020.12.202 · Cited by 312
Cited by
Chitosan-based self-healing hydrogel dressing for wound healing
Zhang, X., Liang, Y., Huang, S., & Guo, B. (2024) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2024.103267 · Cited by 401
Lee, S. J., Gwak, M. A., Chathuranga, K., Lee, J. S., Koo, J., & Park, W. H. (2023) · Food Hydrocolloids · doi:10.1016/j.foodhyd.2022.108249 · Cited by 259
Recent advances in tannic acid-based gels: Design, properties, and applications
Tang, Z., Chowdhury, I. F., Yang, J., Li, S., Mondal, A. K., & Wu, H. (2025) · Advances in Colloid and Interface Science · doi:10.1016/j.cis.2025.103425 · Cited by 70
Metadata
- Authors
- Pan, W., Qi, X., Xiang, Y., You, S., Cai, E., Gao, T., Tong, X., Hu, R., Shen, J., & Deng, H.
- Venue
- International Journal of Biological Macromolecules
- Publisher
- Elsevier BV
- Published
- 2022-01
- Volume
- 195
- Pages
- 190-197
- ISSN
- 0141-8130 (ISSN-L)
- OpenAlex
- W4200153950
- Cited by
- 266
- References
- 45
- FWCI
- 19.89
- Type
- journal article
- Language
- en
- Open access
- closed
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- The paper
- Pan, W., Qi, X., Xiang, Y., You, S., Cai, E., Gao, T., Tong, X., Hu, R., Shen, J., & Deng, H. (2022). Facile formation of injectable quaternized chitosan/tannic acid hydrogels with antibacterial and ROS scavenging capabilities for diabetic wound healing. International Journal of Biological Macromolecules. https://doi.org/10.1016/j.ijbiomac.2021.12.007
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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