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Cost-of-illness and disease burden of food-related pathogens in the Netherlands, 2011
Open accessAbstract
To inform risk management decisions on control and prevention of food-related disease, both the disease burden expressed in Disability Adjusted Life Years (DALY) and the cost-of-illness of food-related pathogens are estimated and presented. Disease burden of fourteen pathogens that can be transmitted by food, the environment, animals and humans was previously estimated by Havelaar et al. (2012). In this paper we complement these by cost-of-illness estimates. Together, these present a complete picture of the societal burden of food-related diseases. Using incidence estimates for 2011, community-acquired non-consulting cases, patients consulting their general practitioner, hospitalized patients and the incidence of sequelae and fatal cases, estimates were obtained for DALYs, direct healthcare costs (e.g. costs for doctor's fees, hospitalizations and medicines), direct non-healthcare costs (e.g. travel costs to and from the doctor), indirect non-healthcare costs (e.g. productivity loss, special education) and total costs. The updated disease burden for 2011 was equal to 13,940 DALY/year (undiscounted) or 12,650 DALY/year (discounted at 1.5%), and was of the same magnitude as previous estimates. At the population-level thermophilic Campylobacter spp., Toxoplasma gondii and rotavirus were associated with the highest disease burden. Perinatal listeriosis infection was associated with the highest DALY per symptomatic case. The total cost-of-illness in 2011 of fourteen food-related pathogens and associated sequelae was estimated at € 468 million/year, if undiscounted, and at € 416 million/year if discounted by 4%. Direct healthcare costs accounted for 24% of total costs, direct non-healthcare costs for 2% and indirect non-healthcare costs for 74% of total costs. At the population-level, norovirus had the highest total cost-of-illness in 2011 with € 106 million/year, followed by thermophilic Campylobacter spp. (€ 76 million/year) and rotavirus (€ 73 million/year). Cost-of-illness per infected case varied from € 150 for Clostridium perfringens intoxications to € 275,000 for perinatal listeriosis. Both incident cases and fatal cases are more strongly correlated with COI/year than with DALY/year. More than 40% of all cost-of-illness and DALYs can be attributed to food, in total € 168 million/year and 5,150 DALY/year for 2011. Beef, lamb, pork and poultry meat alone accounted for 39% of these costs. Products of animal origin accounted for € 86 million/year (or 51% of the costs attributed to food) and 3,320 DALY/year (or 64% of the disease burden attributed to food). Among the pathogens studied Staphylococcus aureus intoxications accounted for the highest share of costs attributed to food (€ 47.1 million/year), followed by Campylobacter spp. (€ 32.0 million/year) and norovirus (€ 17.7 million/year).
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“The limited data from LMIC on reported FBD by food source show a similar pattern to the data from HIC (Fig. 1) (Painter et al., 2013;Sudershan et al., 2014;Mangen et al., 2015;Tam et al., 2012;Sang et al., 2014).”
From Burden of foodborne disease in low-income and middle-income countries and opportunities for scaling food safety interventions (2023) · cites this paper as Mangen et al., 2015
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Cites
Foodborne illness acquired in the United States—Major pathogens
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Self-citationDisease burden of foodborne pathogens in the Netherlands, 2009
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Campylobacteriosis: the role of poultry meat
Skarp, C. P. A., Hänninen, M., & Rautelin, H. (2015) · Clinical Microbiology and Infection · doi:10.1016/j.cmi.2015.11.019 · Cited by 464
Foodborne viruses: Detection, risk assessment, and control options in food processing
Bosch, A., Gkogka, E., Guyader, F. S. L., Loisy, F., Lee, A., van Lieshout, L., Marthi, B., Myrmel, M., Sansom, A., Schultz, A. C., et al. (2018) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2018.06.001 · Cited by 290
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Epidemiology, Pathophysiology, Diagnosis, and Management of Cerebral Toxoplasmosis
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Prioritisation of food-borne parasites in Europe, 2016
Bouwknegt, M., Devleesschauwer, B., Graham, H. E., Robertson, L. J., van der Giessen, J. W. B., & participants, T. E.-F. W. (2018) · Eurosurveillance · doi:10.2807/1560-7917.es.2018.23.9.17-00161 · Cited by 216
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Metadata
- Authors
- Mangen, M.-J. J., Bouwknegt, M., Friesema, I. H. M., Haagsma, J. A., Kortbeek, L. M., Tariq, L., Wilson, M., van Pelt, W., & Havelaar, A. H.
- Affiliations
- University Medical Center Utrecht (NL)
- National Institute for Public Health and the Environment (NL)
- Utrecht University (NL)
- Corresponding author
- Bouwknegt, Martijn
- ORCID
- Venue
- International Journal of Food Microbiology
- Publisher
- Elsevier BV
- Published
- 2015-03
- Volume
- 196
- Pages
- 84-93
- ISSN
- 0168-1605 (ISSN-L)
- OpenAlex
- W2054278554
- Cited by
- 140
- References
- 36
- Citations by year
- 2026: 2 · 2025: 8 · 2024: 9 · 2023: 11 · 2022: 15 · 2021: 8 · 2020: 14 · 2019: 17 · 2018: 23 · 2017: 12 · 2016: 17 · 2015: 3
- FWCI
- 15.76
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- International Journal of Food Microbiology (publishedVersion)
- PubMed (publishedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Rivm (National Institute for Public Health and the Environment) (submittedVersion)
- Utrecht University Repository (Utrecht University) (submittedVersion)
- Funders
- Rijksinstituut voor Volksgezondheid en Milieu
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Salmonella and Campylobacter epidemiology
- Life Sciences › Agricultural and Biological Sciences › Food Science › Food Safety and Hygiene
- Life Sciences › Agricultural and Biological Sciences › Food Science › Listeria monocytogenes in Food Safety
- Keywords
- foodborne pathogens, economic burden, disease burden, disability-adjusted life years, norovirus, thermophilic Campylobacter, rotavirus, perinatal listeriosis, Toxoplasma gondii, Clostridium perfringens, health care costs, food safety risk management, Netherlands, incidence and mortality
- MeSH terms
- Animals, Food Microbiology, Humans, Listeriosis, Meat, Netherlands, Incidence, Health Care Costs, Caliciviridae Infections, Cost of Illness, Norovirus
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