PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up

Nano based drug delivery systems: recent developments and future prospects

Patra, J. K., Das, G., Fraceto, L. F., Campos, E. V. R., Rodríguez-Torres, M. D. P., Acosta‐Torres, L. S., Diaz-Torres, L. A., Grillo, R., Swamy, M. K., Sharma, S., et al. (2018) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0392-8 · Cited by 7,085

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier

Makadia, H. K., & Siegel, S. J. (2011) · Polymers · doi:10.3390/polym3031377 · Cited by 4,816

Biodegradable polymeric nanoparticles based drug delivery systems

Kumari, A., Yadav, S. K., & Yadav, S. C. (2009) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2009.09.001 · Cited by 3,755

Block copolymer micelles for drug delivery: design, characterization and biological significance

Kataoka, K., Harada, A., & Nagasaki, Y. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00124-1 · Cited by 3,506

The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices

Jain, R. A. (2000) · Biomaterials · doi:10.1016/s0142-9612(00)00115-0 · Cited by 2,214

Nanoparticles in the clinic: an update

Anselmo, A. C., & Mitragotri, S. (2019) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10143 · Cited by 1,766

Polymer nanoparticles: Preparation techniques and size-control parameters

Rao, J. P., & Geckeler, K. E. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.01.001 · Cited by 1,731

An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering

Gentile, P., Chiono, V., Carmagnola, I., & Hatton, P. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15033640 · Cited by 1,593

Properties of lactic acid based polymers and their correlation with composition

Södergård, A., & Stolt, M. (2002) · Progress in Polymer Science · doi:10.1016/s0079-6700(02)00012-6 · Cited by 1,461

Dendrimers and dendritic polymers in drug delivery

Gillies, E. R., & Fréchet, J. M. J. (2005) · Drug Discovery Today · doi:10.1016/s1359-6446(04)03276-3 · Cited by 1,361

Research Progress of Drug Delivery Systems Targeting the Kidneys

Huang, L., Ye, Q.-R., Chen, X., Huang, X., Zhang, Q., Wu, C., Liu, J., & Yang, C. (2024) · Pharmaceuticals · doi:10.3390/ph17050625 · Cited by 15

PEGylated PLGA nanoparticles prepared from nano-emulsion templates as versatile platforms to cross blood-brain barrier models

López-Mitjavila, J.-J., Palma-Florez, S., Lagunas, A., Mir, M., Samitier, J., Rodríguez‐Abreu, C., & Grijalvo, S. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107057 · Cited by 15

Microfluidics-based PLGA nanoparticles of ratiometric multidrug: From encapsulation and release rates to cytotoxicity in human lens epithelial cells

Guo, Y., Li, X., Macgregor, R. B., YAN, H. H., & Zhang, R. (2023) · Heliyon · doi:10.1016/j.heliyon.2023.e18318 · Cited by 14

Process Analytical Strategies for Size Monitoring: Offline, At-Line, Online, and Inline Methods in a Top-Down Nano-Manufacturing Line

Glader, C., Jeitler, R., Wang, Y., van Tuijn, R., Grau‐Carbonell, A., Tetyczka, C., Mesite, S., Caisse, P., Khinast, J., & Roblegg, E. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17060684 · Cited by 13

Preparation of PLGA Nanoparticles by Milling Spongelike PLGA Microspheres

Lee, J., & Sah, H. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14081540 · Cited by 13

Advanced 3D printing and multiscale technologies (nano to macro) for personalized biomedical applications

Balasubramaniyam, S., Rathinam, T., Srinivasan, M., & Elumalai, K. (2025) · Bioprinting · doi:10.1016/j.bprint.2025.e00430 · Cited by 13

Recent advances and future challenges in nanosystems for ocular drug delivery

Shahror, R. A., & Fouda, A. Y. (2025) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/j.jpet.2025.103738 · Cited by 12

Silk fibroin-anastrozole loaded prolonged-release biodegradable nanomedicine: A promising drug delivery system for breast cancer therapy

Nasrine, A., Ahmed, M. G., & Narayana, S. (2022) · Materials Today Proceedings · doi:10.1016/j.matpr.2022.06.101 · Cited by 12

Tyrosine Kinase Inhibitor Lenvatinib Based Nano Formulations and Cutting-Edge Scale-Up Technologies in revolutionizing Cancer Therapy

Shaikh, S., Chary, P. S., & Mehra, N. K. (2025) · ACS Applied Bio Materials · doi:10.1021/acsabm.4c01527 · Cited by 13

Optimisation of a Microfluidic Method for the Delivery of a Small Peptide

Han, F. Y., Xu, W., Kumar, V., Cui, C. S., Li, X. X., Jiang, X., Woodruff, T. M., Whittaker, A. K., & Smith, M. T. (2021) · Pharmaceutics · doi:10.3390/pharmaceutics13091505 · Cited by 12

Colistin-loaded aerosolizable particles for the treatment of bacterial respiratory infections

Landa, G., Alejo, T., Sauzet, T., Laroche, J., Sebastián, V., Tewes, F., & Arruebo, M. (2023) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2023.122732 · Cited by 12

PLGA Nanoparticle Rapamycin- or Necrostatin-1-Coated Sutures Inhibit Inflammatory Reactions after Arterial Closure in Rats

Zhang, L., Wang, W., Xie, B., Sun, P., Wei, S., Wu, H., Zhang, C., Li, J., Li, Z. Y., & Bai, H. (2022) · ACS Applied Bio Materials · doi:10.1021/acsabm.1c01256 · Cited by 12

α-Acylamino-β-lactone N-Acylethanolamine-hydrolyzing Acid Amidase Inhibitors Encapsulated in PLGA Nanoparticles: Improvement of the Physical Stability and Protection of Human Cells from Hydrogen Peroxide-Induced Oxidative Stress

Gagliardi, A., Molinaro, R., Fresta, M., Duranti, A., & Cosco, D. (2022) · Antioxidants · doi:10.3390/antiox11040686 · Cited by 12

Inhalable Nanomaterial Discoveries for Lung Cancer Therapy: A Review

Safdar, I., Mahmood, S., Abdulwahab, M. K., Noor, S. M., Ge, Y., & Sofian, Z. M. (2025) · Pharmaceutics · doi:10.3390/pharmaceutics17080996 · Cited by 11

Neonatal Pharmacokinetics and Biodistribution of Polymeric Nanoparticles and Effect of Surfactant

Xu, N., Wong, M., Balistreri, G. N., & Nance, E. A. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15041176 · Cited by 11

Encapsulation of Neem oil from Azadirachta indica into Poly (lactic-co-glycolic acid) as a novel sprayable miticide system with long-term storage stability and controlled release kinetic

Moeini, A., Pedram, P., Goudoulas, T. B., Mehlhorn-Diehl, T., Gestmann, F., Fattahi, E., Becker, T. M., & Germann, N. (2023) · Industrial Crops and Products · doi:10.1016/j.indcrop.2023.116954 · Cited by 20

Long-term release of bioactive interferon-alpha from PLGA-chitosan microparticles: in vitro and in vivo studies

Fleitas‐Salazar, N., Lamazares, E., Pedroso‐Santana, S., Kappes, T., Alonso, A. P., Hidalgo-Gajardo, A., Altamirano, C., Sánchez, O., Fernández, K. F., & Toledo, J. R. (2022) · Biomaterials Advances · doi:10.1016/j.bioadv.2022.213167 · Cited by 12

Computational simulation and target prediction studies of solubility optimization of decitabine through supercritical solvent

Alshahrani, S. M., Almutairy, B. K., Alfadhel, M. M., Belal, A., Abourehab, M. A. S., Saqr, A. A., Alshetaili, A., Venkatesan, K., Alsubaiyel, A. M., & Pishnamazi, M. (2022) · Scientific Reports · doi:10.1038/s41598-022-21233-0 · Cited by 11

Exploring the potential of polymers: advancements in oral nanocarrier technology

Silva, R. D. A., Arruda, I. E. S., Chaves, L. L., Soares, M. F. D. L. R., & Soares‐Sobrinho, J. L. (2025) · Beilstein Journal of Nanotechnology · doi:10.3762/bjnano.16.122 · Cited by 11

Lenalidomide promotes melarsoprol-activated cGAS-STING-mediated immunotherapy for hepatocellular carcinoma via attenuating TNF-α activity

Yu, Z., Zou, Y., Han, S., Sun, D., Wang, L., Yang, L., Li, Y., Zhang, X., & Guo, J. (2023) · Fundamental Research · doi:10.1016/j.fmre.2023.05.013 · Cited by 10

Targeted delivery of rifaximin using P6.2-decorated bifunctional PLGA nanoparticles for combating Staphylococcus aureus infections

Arayıcı, P. P., Coksu, I., Özbek, T., & Acar, S. (2024) · Biomaterials Advances · doi:10.1016/j.bioadv.2024.213862 · Cited by 10

Harnessing the Power of Nanocarriers to Exploit the Tumor Microenvironment for Enhanced Cancer Therapy

Al‐Dhubiab, B. E., Almuqbil, R. M., & Nair, A. B. (2025) · Pharmaceuticals · doi:10.3390/ph18050746 · Cited by 12

Preparation and characterization of PLGA nanoparticles

Cornu, R., Laurent, G., & Béduneau, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91215-0.00012-1 · Cited by 10

Delivery of Immunostimulatory Cargos in Nanocarriers Enhances Anti-Tumoral Nanovaccine Efficacy

Schunke, J., Mailänder, V., Landfester, K., & Fichter, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241512174 · Cited by 11

Intranasal administration enhances size-dependent pulmonary phagocytic uptake of poly(lactic-co-glycolic acid) nanoparticles

Baek, S. H., Hwang, E.-H., Hur, G. H., Kim, G., An, Y. J., Park, J., & Hong, J. J. (2024) · EJNMMI Radiopharmacy and Chemistry · doi:10.1186/s41181-023-00227-x · Cited by 9

Designing multitarget ligands for neurodegenerative diseases with improved permeability trough PLGA nanoencapsulation

Nozal, V., Fernández-Gómez, P., García‐Rubia, A., Martínez‐González, L., Cuevas, E. P., Carro, E., Palomo, V., & Martı́nez, A. (2024) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2024.116626 · Cited by 9

Engineered biomimetic cell membrane-coated polymeric nanostructures for cancer therapy

Faria, M., Ferreira-Faria, I., Sousa‐Oliveira, I., Pires, P. C., Hameed, H., Silva, F., Moço, G., Ren, J., Zare‬, E. N., Guo, Z., et al. (2025) · Materials Today Chemistry · doi:10.1016/j.mtchem.2024.102506 · Cited by 9

Production of PLGA Nanoparticles via Nanoprecipitation: A Systemic Study on Synthesis Conditions

Wei, Y., Xu, F., Xu, R., Li, X., Yang, Y., Long, R., Li, N., & Yuan, B. (2025) · Chemical Research in Chinese Universities · doi:10.1007/s40242-025-5042-8 · Cited by 9

Enhanced photodynamic therapy of curcumin using biodegradable PLGA coated mesoporous silica nanoparticles

Amin, M. U., Ali, S., Engelhardt, K. H., Nasrullah, U., Preis, E., Schaefer, J., Pfeilschifter, J. M., & Bakowsky, U. (2024) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2024.114503 · Cited by 9

Polymeric nanoparticles targeting Sialyl-Tn in gastric cancer: A live tracking under flow conditions

Diniz, F., Azevedo, M. M., Sousa, F., Osório, H., Campos, D., Sampaio, P., Gomes, J., Sarmento, B. F. C. C., & Reis, C. A. (2022) · Materials Today Bio · doi:10.1016/j.mtbio.2022.100417 · Cited by 9

A Versatile Brij-Linker for One-Step Preparation of Targeted Nanoparticles

Anzengruber, M., Nepustil, L. M., Kurtaj, F., Tahir, A., Skoll, K., Sami, H., Wirth, M., & Gabor, F. (2023) · Pharmaceutics · doi:10.3390/pharmaceutics15051403 · Cited by 9

Carrier cascade target delivery of 5-aminolevulinic acid nanoplatform to enhance antitumor efficiency of photodynamic therapy against lung cancer

Li, Z., Song, Y., Luo, Q., Liu, Z., Man, Y., Liu, J., Lu, Y., & Zheng, L. (2024) · Journal of Photochemistry and Photobiology B Biology · doi:10.1016/j.jphotobiol.2024.112999 · Cited by 8

Exploring the Potential of PLGA Nanoparticles for Enhancing Pulmonary Drug Delivery

Costa, M. P., Abdu, J. O. C., de Moura, M. F. C. S., Silva, A. C., Zacaron, T. M., de Paiva, M. R. B., Fabri, R. L., Pittella, F., Perrone, Í. T., & Tavares, G. D. (2025) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.5c00118 · Cited by 11

Magnetic nanoparticle as a new cutting-edge drug delivery and diagnostic platform: a review on its properties, synthesis, surface modification and applications

Das, A., Sengupta, P., Khanam, J., Augustine, R., Thakor, A. S., Thomas, S., Roy, S., & Ghosal, K. (2025) · Carbohydrate Polymer Technologies and Applications · doi:10.1016/j.carpta.2025.100905 · Cited by 9

Mechanisms and Nanomedicine Interventions of Acute Lung Injury Induced by Intestinal Ischemia-Reperfusion: A Mini Review

Li, G., Jin, B., Zhou, J., Sun, T., Wang, S., & Fan, Z. (2025) · International Journal of Nanomedicine · doi:10.2147/ijn.s533797 · Cited by 8

Clinical translation of PLGA nanoparticles into market—From benchside to breakthrough therapy

Jani, K., & Kaushal, N. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91215-0.00013-3 · Cited by 8

PLGA-PEG Nanoparticles Loaded with Cdc42 Inhibitor for Colorectal Cancer Targeted Therapy

Kadyr, S., Zhuraliyeva, A., Yermekova, A., Makhambetova, A., Kaldybekov, D. B., Mun, E. A., Bulanin, D. S., Askarova, S., & Umbayev, B. A. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16101301 · Cited by 8

Inflammatory Bowel Disease: Exploring Pathogenesis, Epidemiology, Conventional Therapies, and Advanced Nanoparticle Based Drug Delivery Systems

Rajput, I. B., Khan, D., Mirza, R., Ahmed, N., Shah, S. U., Asad, M., Gibaud, S., & Shah, K. U. (2025) · BioNanoScience · doi:10.1007/s12668-025-01809-6 · Cited by 8

Characterization and Preliminary In Vitro Antioxidant Activity of a New Multidrug Formulation Based on the Co-Encapsulation of Rutin and the α-Acylamino-β-Lactone NAAA Inhibitor URB894 within PLGA Nanoparticles

Gagliardi, A., Voci, S., Ambrosio, N., Fresta, M., Duranti, A., & Cosco, D. (2023) · Antioxidants · doi:10.3390/antiox12020305 · Cited by 8

Drug loading methods and drug release mechanisms of PLGA nanoparticles

Kırımlıoğlu, G. Y. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-91215-0.00005-4 · Cited by 8

Self‐Sustained Nanobiomaterials

Datta, S., Das, S., & Barua, D. R. (2023) · Wiley eBooks · doi:10.1002/9781394166985.ch12 · Cited by 8

Engineering pH-sensitive dissolution of lipid-polymer nanoparticles by Eudragit integration impacts plasmid DNA (pDNA) transfection

Santhanes, D., Zhang, H., Wilkins, A., Aitken, R. J., Gannon, A., & Liang, M. (2024) · European Journal of Pharmaceutics and Biopharmaceutics · doi:10.1016/j.ejpb.2024.114299 · Cited by 7

Thermoresponsive Nanocarriers Transduced by Inorganic Nanoparticles: Design Considerations and Applications in Drug Delivery

Nikoletić, A., Maleković, M., Kozalak, G., Palivan, C. G., & Tagit, O. (2025) · Helvetica Chimica Acta · doi:10.1002/hlca.202400193 · Cited by 8

Synthesis of 5-Fluorouracil (5-FU) coated platinum nanoparticles and apoptotic effects on U87 human glioblastoma cells

Abed, A., Karimi, M., Nejati, M., Hamblin, M. R., Mirzaei, S. A., Sarvizadeh, M., & Mirzaei, H. (2025) · Cancer Cell International · doi:10.1186/s12935-025-03893-w · Cited by 8

Clinical hurdles for curcumin and piperine nanoparticles in prostate cancer treatment: a bridge too far or a path to clinical reality?

Yakubu, J. Y., Tagit, O., & Pandey, A. V. (2026) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2026.2619094 · Cited by 7

Hybrid Silica-Coated PLGA Nanoparticles for Enhanced Enzyme-Based Therapeutics

Gustafson, K. T., Mokhtari, N., Manalo, E. C., Mira, J. M., Gower, A., Yeh, Y., Vaidyanathan, M., Esener, S. C., & Fischer, J. M. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics15010143 · Cited by 7

Effect of Composition and Size on Surface Properties of Anti-Cancer Nanoparticles

Mishra, I., Garrett, M., Curry, S. H., Jameson, J. T., & Kastellorizios, M. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241713417 · Cited by 7

A Review of the Potential of Poly-(lactide-co-glycolide) Nanoparticles as a Delivery System for an Active Antimycobacterial Compound, 7-Methyljuglone

Diedericks, B., Kok, A., Mandiwana, V., & Lall, N. (2024) · Pharmaceutics · doi:10.3390/pharmaceutics16020216 · Cited by 7

Advances in nano‐preparations for improving tetrandrine solubility and bioavailability

Ling, J., Wu, J., Cao, Y., Zhang, T., Cao, X., Ge, X., Liu, Y., Wang, M., Ren, B., & Lu, J. G. (2024) · Archiv der Pharmazie · doi:10.1002/ardp.202400274 · Cited by 7

Baicalin loaded monodispersed polycaprolactone (PCL) microspheres preparation by polyvinylidene fluoride (PVDF) membrane emulsification for wound healing in dermal fibroblasts

Zhong, W., Cao, X., Zeng, H., Tang, M., Li, G., Xiong, J., Wang, Y., Guo, L., & Ji, J. (2025) · Journal of Biomaterials Applications · doi:10.1177/08853282251321259 · Cited by 7

Quaternized chitosan-coated PLGA nanoparticles co-deliver resveratrol and all-trans retinoic acid to enhance humoral immunity, cellular immunity and gastrointestinal mucosal immunity

Yang, D., Wang, N., Cao, L., Liu, H., Cheng, H., Ma, H., Li, L., Zou, Y., Zhao, X., Zhou, X. C., et al. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.114994 · Cited by 7

Biofunctionalized polymeric nanoparticles for the enhanced delivery of erlotinib in cancer therapy

Tıwarı, R., Patil, A., Verma, R., Deva, V., Rudrangi, S. R. S., Bhise, M. R., & Vinukonda, A. (2024) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2024.2429328 · Cited by 6

Reprogramming the melanoma and immunosuppressive myeloid cells with esomeprazole-loaded PLGA nanoparticles

Cerioli, N., Bououdina, W., Mereu, A., Natsaridis, E., Salsetta, J., Cova, A., Lupoli, G., D’Angelo, E., Rivoltini, L., Figdor, C. G., et al. (2024) · iScience · doi:10.1016/j.isci.2024.111559 · Cited by 6

Nanoparticle-based CRISPR/Cas Delivery: An Emerging Tactic for Cancer Therapy

Dilnawaz, F., & Acharya, S. (2022) · Current Medicinal Chemistry · doi:10.2174/0929867329666221006112615 · Cited by 7

Caveat Emptor: Commercialized Manganese Oxide Nanoparticles Exhibit Unintended Properties

de la Torre, C. M., Freshwater, K. A., Looney-Sanders, M. A., Wang, Q., & Bennewitz, M. F. (2023) · ACS Omega · doi:10.1021/acsomega.3c00892 · Cited by 6

Nanoformulation of the Broad-Spectrum Hydrophobic Antiviral Vacuolar ATPase Inhibitor Diphyllin in Human Recombinant H-ferritin

Vojníková, M., Sukupova, M., Štefánik, M., Straková, P., Haviernik, J., Kapolkova, K., Gruberova, E., Raskova, K., Michalkova, H., Svec, P., et al. (2024) · International Journal of Nanomedicine · doi:10.2147/ijn.s452119 · Cited by 6

Improved cognition and memory via PLGA nanoparticle-mediated delivery of curcumin and piperine in an in vivo Alzheimer’s disease model

Phuna, Z. X., Vijayabalan, S., Panda, B. P., Shivashekaregowda, N. K. H., Shaikh, M. F., & Madhavan, P. (2025) · Drug Delivery and Translational Research · doi:10.1007/s13346-025-01945-2 · Cited by 8

Poly(lactic-co-glycolic acid) nanoparticles and microparticles for peptide delivery: release mechanisms and controlling factors

Eshaghi, M., Dehghani, M., Abedi, A., Moghaddam, M. M., & Taheri, R. A. (2025) · ADMET & DMPK · doi:10.5599/admet.3091 · Cited by 5

Nanocarrier-based Drug Delivery Systems to Enhance Antimicrobial Photodynamic Therapy in Dental Applications: A Review

Ebrahimi, N., Hassani, A. R., Shahabi, S., & Afrasiabi, S. (2025) · AAPS PharmSciTech · doi:10.1208/s12249-025-03155-y · Cited by 5

Etoposide-Loaded Colloidal Delivery Systems Based on Biodegradable Polymeric Carriers

Merkulova, M. A., Osipova, N., Kalistratova, A. V., Ermolenko, Y. V., & Gelperina, S. E. (2023) · Colloid Journal · doi:10.1134/s1061933x23600744 · Cited by 5

A Versatile, Low-Cost Modular Microfluidic System to Prepare Poly(Lactic-co-Glycolic Acid) Nanoparticles With Encapsulated Protein

Neustrup, M. A., Ottenhoff, T. H. M., Jiskoot, W., Bouwstra, J. A., & van der Maaden, K. (2024) · Pharmaceutical Research · doi:10.1007/s11095-024-03792-1 · Cited by 5

Transfusion biomaterials for hemostasis

Pozy, E. J., & Brown, A. C. (2024) · Journal of Thrombosis and Haemostasis · doi:10.1016/j.jtha.2024.11.030 · Cited by 5

Hydrophobic Derivatives of Sulfated Hyaluronic Acid as Drug Delivery Systems for Multi-Target Intra-Articular Treatment of Post-Traumatic Osteoarthritis

Guarise, C., Tessari, M., Pavan, M., Pluda, S., Lucia, A. D., Barbera, C., & Galesso, D. (2022) · Journal of Pharmaceutical Sciences · doi:10.1016/j.xphs.2022.04.003 · Cited by 5

Subcellular organelle-mediated precise delivery of nanomedicines: Advances and applications in cancer therapy

Dang, W., Cui, T., Jiao, G., Li, J., & Liu, Z. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107261 · Cited by 5

Surface-modified organic nanoparticles for lung cancer targeted therapy

Gündel, S. D. S., Alves, A. D. C. S., Dallemole, D. R., Guterres, S. S., & Pohlmann, A. R. (2025) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2025.115175 · Cited by 4

Emerging Roles of polymeric nanoparticles in cancer Therapy: Design, Targeting, and clinical integration

Sheykholeslami, S. E., Halimi, S., Ahangari, F., Mohammadgholi, A., Mansouri, A., Dehaghi, H. M., Eynakchi, M. K., Hosseini, S., Tahouri, S. K. S., Shahbazi, Z., et al. (2025) · European Polymer Journal · doi:10.1016/j.eurpolymj.2025.114447 · Cited by 4

Optimization of Lurasidone HCl-Loaded PLGA Nanoparticles for Intramuscular Delivery: Enhanced Bioavailability, Reduced Dosing Frequency, Pharmacokinetics, and Therapeutic Outcomes

Macwan, N., Patel, H. S., Sharma, R. K., Jain, N., & Tandel, H. (2023) · Assay and Drug Development Technologies · doi:10.1089/adt.2023.089 · Cited by 4

Machine learning-aided tailoring of double-emulsions within double-T microchannel

Bariki, S. G., Movahedirad, S., & layaei, M. B. (2024) · Microfluidics and Nanofluidics · doi:10.1007/s10404-024-02758-4 · Cited by 4

Bionanoremediation of wastewater: an innovative and novel approach

Rath, S. C., Bhagawati, U., & Goel, A. (2025) · Environmental Monitoring and Assessment · doi:10.1007/s10661-025-13943-5 · Cited by 5

Silver nanoparticles and protein polymer-based nanomedicines

Abdussalam-Mohammed, W., Amar, I. A., Almaky, M. M., Abdelhameed, A., & Errayes, A. O. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-90545-9.00003-3 · Cited by 4

Mathematical Modeling and Numerical Simulations for Drug Release from PLGA Particles

Sun, Y., Li, Y., & Liu, J. (2023) · Lecture notes in computer science · doi:10.1007/978-3-031-36030-5_28 · Cited by 4

Construction of esterase-responsive hyperbranched polyprodrug micelles and their antitumor activity in vitro

Qiao, J., Li, S., Yuan, H., Wang, Y., Li, J., Wang, P., & Duan, X. (2022) · e-Polymers · doi:10.1515/epoly-2022-0047 · Cited by 4

Utility of various drug delivery systems and their advantages and disadvantages

Fatima, H., Shukrullah, S., Hussain, H., Aslam, H., & Naz, M. Y. (2023) · Elsevier eBooks · doi:10.1016/b978-0-323-95325-2.00015-8 · Cited by 4

Development of computational intelligence models for assessment of drug nanonization using green chemistry technique: Improvement of drug solubility

Huwaimel, B., & Alharby, T. N. (2023) · Case Studies in Thermal Engineering · doi:10.1016/j.csite.2023.103005 · Cited by 4

Sustainability in Drug and Nanoparticle Processing

Fischer, D. (2023) · Handbook of experimental pharmacology · doi:10.1007/164_2023_659 · Cited by 4

Recent Advances in the Functionalized Poly(α-Hydroxy Acids) Synthesized fromO-Carboxyanhydrides

Huo, Z., Xie, X., & Tong, R. (2023) · ACS symposium series · doi:10.1021/bk-2023-1451.ch005 · Cited by 4

A Revolutionary Approach for Combating Efflux Transporter-mediated Resistant Epilepsy: Advanced Drug Delivery Systems

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