PLGA-based nanomedicines manufacturing: Technologies overview and challenges in industrial scale-up

Nano based drug delivery systems: recent developments and future prospects

Patra, J. K., Das, G., Fraceto, L. F., Campos, E. V. R., Rodríguez-Torres, M. D. P., Acosta‐Torres, L. S., Diaz-Torres, L. A., Grillo, R., Swamy, M. K., Sharma, S., et al. (2018) · Journal of Nanobiotechnology · doi:10.1186/s12951-018-0392-8 · Cited by 7,085

Poly Lactic-co-Glycolic Acid (PLGA) as Biodegradable Controlled Drug Delivery Carrier

Makadia, H. K., & Siegel, S. J. (2011) · Polymers · doi:10.3390/polym3031377 · Cited by 4,816

Biodegradable polymeric nanoparticles based drug delivery systems

Kumari, A., Yadav, S. K., & Yadav, S. C. (2009) · Colloids and Surfaces B Biointerfaces · doi:10.1016/j.colsurfb.2009.09.001 · Cited by 3,755

Block copolymer micelles for drug delivery: design, characterization and biological significance

Kataoka, K., Harada, A., & Nagasaki, Y. (2001) · Advanced Drug Delivery Reviews · doi:10.1016/s0169-409x(00)00124-1 · Cited by 3,506

The manufacturing techniques of various drug loaded biodegradable poly(lactide-co-glycolide) (PLGA) devices

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Nanoparticles in the clinic: an update

Anselmo, A. C., & Mitragotri, S. (2019) · Bioengineering & Translational Medicine · doi:10.1002/btm2.10143 · Cited by 1,766

Polymer nanoparticles: Preparation techniques and size-control parameters

Rao, J. P., & Geckeler, K. E. (2011) · Progress in Polymer Science · doi:10.1016/j.progpolymsci.2011.01.001 · Cited by 1,731

An Overview of Poly(lactic-co-glycolic) Acid (PLGA)-Based Biomaterials for Bone Tissue Engineering

Gentile, P., Chiono, V., Carmagnola, I., & Hatton, P. (2014) · International Journal of Molecular Sciences · doi:10.3390/ijms15033640 · Cited by 1,593

Properties of lactic acid based polymers and their correlation with composition

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Dendrimers and dendritic polymers in drug delivery

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Molecular dynamics insights into the interactions of biocompatible synthetic polymer composites with carbon-based nanoparticle derivatives: a comparative study of PLGA and PCL interactions with GO/rGO

Çelik, R. H., Şimşek, S., Gel, E., & Acuner, S. E. (2025) · Journal of Computer-Aided Molecular Design · doi:10.1007/s10822-025-00726-w · Cited by 2

Engineering silica nanoparticle-based drug delivery systems for glioblastoma therapy

Munasir, M., Maulana, S. A., Nurlaili, R. A., Taufiq, A., Faaizatunnisa, N., Ariesta, M. N., Suaebah, E., Putri, N. P., Sunaryono, Astuti, S. D., et al. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108178 · Cited by 4

Injectable thermosensitive hydrogels for sustained intra-articular release of TNF-α inhibitors in rheumatoid arthritis

Miyanroodan, S. M., & Sohail, M. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.126726 · Cited by 2

Combined PLGA scaffolds and therapeutic stem cells for locomotion recovery in spinal cord-injured rats: a systematic review and meta-analysis

Tang, L., Xie, Q., Li, S., Liu, Z., Yu, Z., & Qian, K. (2026) · Scientific Reports · doi:10.1038/s41598-026-45065-4 · Cited by 2

Mapping Nanoscale Protein‐Corona Kinetics of DoE‐Optimized Perfluorocarbon Encapsulated‐PLGA Nanoparticles by In Situ, Time‐Resolved Synchrotron SAXS

Joseph, J. M., Gigliobianco, M. R., Minnelli, C., Moretti, P., Spinozzi, F., Mobbili, G., Pistolesi, S., Casadidio, C., Teti, G., Censi, R., et al. (2026) · Advanced Healthcare Materials · doi:10.1002/adhm.202505091 · Cited by 2

Nanotechnology-Assisted Co-Delivery of Immunotherapeutic Agents for Targeting Ovarian Cancer: Prospects and Challenges

Jiao, L., Li, M., Tan, M., ZHENG, L., Liu, Y., & Cao, Y. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s603950 · Cited by 3

Sequential eradication of bacterial persisters: integrating phytochemical pharmacology with microenvironment-responsive delivery strategies

Bai, J., Han, L., Cheng, X., Fu, H., Zhang, X., He, H., & Wang, J. (2026) · Frontiers in Microbiology · doi:10.3389/fmicb.2026.1842301 · Cited by 2

Nanotechnologies for Skin Drug Delivery: Polymeric, Bio-Based, and Hybrid Nanocarriers with Clinical and Translational Perspectives

Eltaib, L., Alotaibi, H., Hamod, M. A., Alfuraih, S., Hamood, N. A., Balkhair, A. M., & Aljasser, A. (2026) · Pharmaceuticals · doi:10.3390/ph19071057 · Cited by 2

Synthetic and Natural Polymeric Drug Delivery Systems - A Comprehensive Overview of Polycaprolactone and Glucan Particles

Bernardi, N. S., Jesus, S., & Borges, O. (2023) · Journal of biomimetics, biomaterials and biomedical engineering · doi:10.4028/p-ns8294 · Cited by 2

Hybrid Bioscaffolds Formation Using Natural and Synthetic Materials for Cartilage Tissue Engineering: The Case of Fibrin, Atelocollagen and Poly(Lactic-co-Glycolic Acid)

Sha’ban, M., & Radzi, M. A. A. (2023) · Springer eBooks · doi:10.1007/978-981-99-2267-3_16 · Cited by 2

Design, optimization, and evaluation of methotrexate loaded and albumin coated polymeric nanoparticles

Tiwari, G., Patil, A., Sethi, P., Agrawal, A., Ansari, V. A., Posa, M. K., & Aher, V. D. (2024) · Journal of Biomaterials Science Polymer Edition · doi:10.1080/09205063.2024.2366619 · Cited by 12

Genetic-bioengineering of nanotechnology in cell-specific pharmaceutical targeting: Biological, pharmacological, and biochemical impact of nanomaterials-based breast cancer therapies

Mohammadi, J., Ebrahimi, S., Ghodousi, M., Mahmoodi, M., Hheidari, A., Pishbin, E., Kharaba, Z. J., Rahdar, A., & Ferreira, L. F. R. (2024) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2024.106249 · Cited by 3

Recent advances in biodegradable polymers for obstetrics and gynecology applications

Xu, J., & Liu, J. (2025) · International Journal of Polymeric Materials · doi:10.1080/00914037.2024.2355188 · Cited by 2

Advancing Nanotechnology in Targeted Cancer Therapy: From Passive Targeting to Smart Delivery Systems

Fahmy, A. M. (2025) · Premier journal of science. · doi:10.70389/pjs.100052 · Cited by 2

Long-lasting Cross-linked PLGA-Inspired Nanoparticlesfrom One-pot Nanopolymerization of Precisely Sequenced Short Oligolactoglycolic Acid DimethacrylatesPreprint

Blagojevic, L., & Kamaly, N. (2023) · ChemRxiv · doi:10.26434/chemrxiv-2023-7v4v4 · Cited by 2

Off-label and repurposed use of disulfiram beyond alcohol dependence: A systematic review of clinical and preclinical evidence

Benkő, B.-M., De Brito Parreirinha, N. S., Sebe, I., & Zelkó, R. (2026) · iScience · doi:10.1016/j.isci.2026.115441 · Cited by 2

Engineering Approaches in Pharmaceutical Research

Rajnath, Y. K., Verma, V. K., & Tiwari, S. (2024) · Advances in healthcare information systems and administration book series · doi:10.4018/979-8-3693-2897-2.ch010 · Cited by 1

Microfluidic Manufacturing of Polymeric Nanoparticles

Chiesa, E., Genta, I., Dorati, R., & Conti, B. (2024) · AAPS introductions in the pharmaceutical sciences · doi:10.1007/978-3-031-60717-2_5 · Cited by 1

Preliminary results on novel adjuvant combinations suggest enhanced immunogenicity of whole inactivated pandemic influenza vaccines

Peletta, A., Marmy, A., Guzelj, S., Barros, A. R., Jakopin, Ž., & Borchard, G. (2024) · Frontiers in Drug Delivery · doi:10.3389/fddev.2024.1382266 · Cited by 1

Challenges and future perspectives of natural biopolymers in drug delivery

Neves, A. R., Albuquerque, T., Eusébio, D., Sousa, Â., & Costa, D. R. B. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95367-2.00017-x · Cited by 1

Harnessing nanoencapsulation for the repurposing of hydroquinidine against breast cancer

Demircan, T., Milinkovic, D., Çetin, E. S., Aksu, E. N., & Tagit, O. (2025) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2025.107098 · Cited by 1

Regulation of response to antigen peptides is independent of peptide distribution in lymph node therapeutics

McIlvaine, R. A., Kapnick, S. M., Carey, S. T., & Jewell, C. M. (2025) · Biomaterials Science · doi:10.1039/d5bm00328h · Cited by 1

Ion-paired antibiotics in PLGA nanoparticles: improving encapsulation efficiency and musculoskeletal infection treatment

Frolov, V., Sovány, T., Loskot, J., Csapó, E., Varga, N., Hassan, A. A. A., Janďourek, O., Konečná, K., Bezrouk, A., & Šnejdrová, E. (2025) · RSC Advances · doi:10.1039/d5ra04263a · Cited by 1

Synthesizing porous nanospheres with highly efficient drug loading and sustained release through a thermal-controlled continuous stirred-tank reactor cascade

Chen, H., Udepurkar, A. P., Clasen, C., Sebastián, V., & Kuhn, S. (2025) · Nanoscale Advances · doi:10.1039/d5na00897b · Cited by 1

Regulatory requirements and clinical trials for nanotechnology-based drug delivery systems for the management of COPD

Hussian, T., Nagar, L., Saini, A., Gulati, N., Gupta, V. K., Dua, G., Tripathy, S., & Dureja, H. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-43946-9.00024-0 · Cited by 1

Harnessing Nano-Enabled Nutrient Delivery Systems for Enhanced Plant Growth

Nuwarapaksha, T. D., Udumann, S. S., Dissanayaka, N. S., Dilshan, N., Gajanayake, B., & Atapattu, A. J. (2026) · Advances in environmental engineering and green technologies book series · doi:10.4018/979-8-3693-7006-3.ch006 · Cited by 1

Advances in nanotechnology for the diagnosis and management of autoimmune diseases

Zheng, Y., Cai, X., Zhang, L., Fei, W., Qin, D., Zhang, X., Zhu, J., Zheng, C., & Yao, Y. (2026) · Asian Journal of Pharmaceutical Sciences · doi:10.1016/j.ajps.2026.101144 · Cited by 3

Electrosprayed PLGA Nanoparticles for Dual Drug Delivery: Design, Optimization and Applications

Azimi, B., Ahmadpoor, F., TOZZI, A., Shahraki, A., Maleki, H., Ferrari, P. F., & Danti, S. (2026) · Polymers · doi:10.3390/polym18091133 · Cited by 4

Nanoparticle Strategies for Bone Metastasis Immunotherapy: Targeting, Immune Reprogramming and Combination Therapy

Bakir, M. A., Alkhatib, A. R., Mustafa, A. R., Raddaoui, M., Al-Kattan, W., & Mohammad, K. S. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18050571 · Cited by 1

Cell-penetrating peptides (CPPs)-engineered PLGA nanocarriers for enhanced drug delivery: Uptake mechanisms, optimization strategies, and therapeutic applications

Malek-Khatabi, A., Rahimzadegan, M., Razavi, M. S., Shabankareh, A. N. T., Sefat, F., & Nosrati, R. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119631 · Cited by 1

Advancing Otology through Nanoparticle-Based Interventions for Inner Ear Treatment

Pang, N. Y., Pang, A. S., Pang, K. Y., Dinesh, T., Wang, D.-Y., & Srinivasan, D. K. (2026) · ACS Applied Nano Materials · doi:10.1021/acsanm.6c01453 · Cited by 1

Polymeric systems for peptide and protein delivery: design principles, translational barriers, and future research directions

Al‐Qaaneh, A. M., & Khanfar, M. S. (2026) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2026.127176 · Cited by 3

Lacticaseibacillus paracasei-derived extracellular vesicles enhance the in vitro efficacy of methylene blue-mediated photodynamic therapy against multidrug-resistant Staphylococcus aureus

Konwar, B., Kashyap, S., Oh, S., & Kim, K.-S. (2026) · Microbiological Research · doi:10.1016/j.micres.2026.128658 · Cited by 1

The Translational Paradox of Cancer Nanomedicine: Biological, Pharmacokinetic, and Manufacturing Barriers to Clinical Success

Jankowska, J., Szeleszczuk, Ł., & Pisklak, D. M. (2026) · Biology · doi:10.3390/biology15171550 · Cited by 1

Surfactants as molecular architects of materials: from interfacial organization to function

Giustra, M., Novati, B., Colombo, A., Sinesi, G., Morelli, L., Garbujo, S., Colombo, M., & Prosperi, D. (2026) · Progress in Materials Science · doi:10.1016/j.pmatsci.2026.101831 · Cited by 1

One-pot synthesis and enzyme-responsiveness of amphiphilic doxorubicin prodrug nanomicelles for cancer therapeutics

Han, L., Wang, K., Ren, Z.-N., Yang, X., Duan, X., Krishnan, S., Jaisankar, A., Park, J.-H., Dashnyam, K., Zhang, W., et al. (2022) · RSC Advances · doi:10.1039/d2ra04436f · Cited by 1

ATIKSUDAN BOYA GİDERİMİNDEKİ GELİŞMELER: ADSORPSİYON TEKNOLOJİSİ VE GELECEĞE YÖNELİK BEKLENTİLER

Yıldız, H. (2024) · Kahramanmaraş Sütçü İmam Üniversitesi Mühendislik Bilimleri Dergisi · doi:10.17780/ksujes.1470859 · Cited by 1

Prospective Utilization of Nanocarriers Loaded with Drug Combination for Treating Alzheimer's Disease

Khan, S. A., Qamar, Z., Rohilla, A., Singh, P. P., Parvez, S., Baboota, S., & Ali, J. (2025) · Current Pharmaceutical Design · doi:10.2174/0113816128348877241202053633 · Cited by 1

RECENT INNOVATIONS IN MICROFABRICATION TECHNIQUES FOR ENHANCED MICROFLUIDIC CHIP PERFORMANCE IN DRUG DEVELOPMENT

ROY, A., Gowdra, V. S., BS, M., Bhargav, E., Pawar, S. D., & RAVI, G. (2025) · International Journal of Applied Pharmaceutics · doi:10.22159/ijap.2025v17i4.54228 · Cited by 1

Etoposide-Loaded Colloidal Delivery Systems Based on Biodegradable Polymeric Carriers

Merkulova, M. A., Osipova, N., Kalistratova, A. V., Ermolenko, Y. V., & Gelperina, S. E. (2023) · Коллоидный журнал · doi:10.31857/s0023291223600463 · Cited by 1

Hybrid DIVEMA/PLGA nanoparticles as the potential drug delivery systemPreprint

Gorshkova, M. Y., Vanchugova, L. V., Osipova, N., Nikitin, A. A., Kotova, J., Kovalenko, E. I., Ermolenko, Y. V., Malinovskaya, J. A., Kovshova, T. S., & Gelperina, S. E. (2024) · Research Square · doi:10.21203/rs.3.rs-4594368/v1 · Cited by 1

Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate CancerPreprint

Yakubu, J., Natsaridis, E., du Toit, T., Barata, I. S., Tagit, O., & Pandey, A. V. (2024) · Research Square · doi:10.21203/rs.3.rs-5326002/v1 · Cited by 1

Advantages of nanoencapsulation in the delivery of therapeutics for bone regeneration

Niclot, F. B., & Taraballi, F. (2025) · Nanomedicine · doi:10.1080/17435889.2025.2462518 · Cited by 1

Drug depots for obesity targeting metabolism, appetite, and inflammation

Fayyaz, M., & Smith, A. M. (2025) · Expert Opinion on Drug Delivery · doi:10.1080/17425247.2025.2554718 · Cited by 1

Treatment activity of budesonide-loaded poly(lactic-co-glycolic acid) microspheres in infant bronchiolitis

Yu, P., & Tian, J. (2022) · Materials Express · doi:10.1166/mex.2022.2296

Establishment of a continuous inline-monitored nano-production line using the Microfluidizer® technology for the fabrication of safe lipid-based nanoparticles

Glader, C., Jeitler, R., Wang, Y., Tetyczka, C., Zettl, M., Khinast, J., Rossano, M., Mesite, S., Lübbert, M., & Roblegg, E. (2023) · Macedonian Pharmaceutical Bulletin · doi:10.33320/maced.pharm.bull.2023.69.03.010

3D-printed microfluidic chips

Mukherjee, A. G., Wanjari, U. R., Murali, R., Kannampuzha, S., Bradu, P., Biswas, A., Renu, K., Vellingiri, B., & Gopalakrishnan, A. V. (2024) · Elsevier eBooks · doi:10.1016/b978-0-443-13782-2.00006-1

A review on Advancements in Nanoparticles Based Pulmonary Drug Delivery

Daniel, A. (2024) · International Journal of Newgen Research in Pharmacy & Healthcare · doi:10.61554/ijnrph.v2i1.2024.88

Comparative cellular toxicity between silver and poly (lactic-co-glycolic acid) nanoparticles

Chaves, M. D. M., Moura, A. L. D., de Sousa, J. S., Ferreira, O. P., Saraiva, K. L. A., Miguel, E. D. C., Savino, W., & Nicolete, R. (2024) · Toxin Reviews · doi:10.1080/15569543.2024.2417894

Nanoparticles with Curcumin and Piperine Modulate Steroid Biosynthesis in Prostate CancerPreprint

Yakubu, J., Natsaridis, E., du Toit, T., Barata, I. S., Tagit, O., & Pandey, A. V. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.24.620019

Preparation, Characterisation and Bioactivity Evaluation of Curcumin-Loaded Poly (Lactic-co-Glycolic Acid) Nanoparticles

Ezzani, M. H., Darnis, D. S., Taher, M., & Abdillah, S. (2024) · Journal of Pharmacy · doi:10.31436/jop.v4i2.304

Pharmaceutical engineering and processes

Wang, Y., & Yang, Z. (2025) · Elsevier eBooks · doi:10.1016/b978-0-323-95392-4.00006-2

Long‐Lasting Cross‐Linked PLGA‐Inspired Nanoparticles from One‐Pot Nanopolymerization of Precisely Sequenced Short Oligolactoglycolic Acid Dimethacrylates

Blagojevic, L., & Kamaly, N. (2025) · Macromolecular Rapid Communications · doi:10.1002/marc.202400778

Unraveling the Mysteries of Brain Cancer from Diagnosis to Treatment

Mathure, D. M., Bhandare, S., Karati, D., Adnan, M., & Kumar, D. (2025) · Pharmaceutical Nanotechnology · doi:10.2174/0122117385331332241226101149

Air Pollution, Nanomaterials, and Bioremediation

Ahmed, S. E. (2025) · Springer eBooks · doi:10.1007/978-981-96-3069-1_9

Nano-Analytical Techniques in Pharmaceutical Analysis

Bindu, C. H., Farmaan, T., Aparna, K., Sadan, M., & Reshma, T. (2025) · Jordan Journal of Pharmaceutical Sciences · doi:10.35516/jjps.v18i2.2631

Filler modification of polymer nanocomposite and fabrication methods

Koech, L. K., Sadiku, E. R., Ramakokovhu, M. M., Premlall, K., & Teffo, M. L. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-24854-2.00011-5

Synthesis of Gold Nanoparticles

Alguno, A. C., Capangpangan, R. Y., Dumancas, G. G., Lubguban, A. A.-O., Malaluan, R. M., & Rivera, R. B. P. (2025) · Engineering materials · doi:10.1007/978-981-96-6565-5_2

Nanoagrochemicals: Ensuring sustainable productivity through nutrient and pest management in strawberry (Fragaria × ananassa Duch.)

Singh, L., Sadawarti, R. K., Thakur, D., SINGH, S. K., & Mirza, A. A. (2025) · Biocatalysis and Agricultural Biotechnology · doi:10.1016/j.bcab.2025.103737

Application of Nanotechnology in Indigenous Fermented Food Products

Boruah, A., Hoque, A., & Tiwari, A. (2025) · Disaster Resilience and Green Growth · doi:10.1007/978-981-96-9286-6_11

Polymeric Nanoparticles in Biopharmaceutical Development

Yelwa, J. M., Musa, H., Drammeh, A., Kalu, K. M., Nzeyimana, P., Alehegn, H. Z., Tanimu, F. B., & Anchau, H. G. (2025) · Progress in drug research · doi:10.1007/978-3-032-00796-4_5

Multifunctional Porous Microshuttles as Scaffolding Components and Carriers of Bioactive Factors in Self‐Assembled Microtissues

Song, K., Giacomini, F., Kaçmaz, E. G., Habibović, P., Truckenmüller, R. K., & Birgani, Z. N. T. (2025) · Small · doi:10.1002/smll.202507968

Reformulating asthma therapy through nano-phytomedicine: Insights into lung health and microplastic exposure

Nizam, A., Hamid, S., Fatima, T., Hasan, M. R., Choudhary, F., Khwaja, H. A., Iqbal, Y., Kumar, S., Abbas, S., & Farooqi, H. (2025) · Journal of Hazardous Materials Plastics · doi:10.1016/j.hazmp.2025.100014

Preparation method: Influence on the properties of colloidal drug delivery systems

Mora‐Huertas, C. E. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-26608-9.00016-0

Additional file 1 of Intranasal administration enhances size-dependent pulmonary phagocytic uptake of poly(lactic-co-glycolic acid) nanoparticles

Baek, S. H., Hwang, E.-H., Hur, G. H., Kim, G., An, Y. J., Park, J.-H., & Hong, J. J. (2024) · Figshare · doi:10.6084/m9.figshare.25231268

Additional file 2 of Intranasal administration enhances size-dependent pulmonary phagocytic uptake of poly(lactic-co-glycolic acid) nanoparticles

Baek, S. H., Hwang, E.-H., Hur, G. H., Kim, G., An, Y. J., Park, J.-H., & Hong, J. J. (2024) · Figshare · doi:10.6084/m9.figshare.25231337

Nanomaterials in Regulating Lipid Metabolism

Patel, P. K., Sen, G., Kathait, P., Malang, S. D., Ankur, Hussain, M. D., & Sahu, A. N. (2025) · Springer eBooks · doi:10.1007/978-981-95-3746-4_7

Enhancing the therapeutic potential of plumbagin in breast cancer via advanced nanomedicine approaches

Sastri, K. T., Gana, N. P., Chandra, N. R., Jain, R., & Jain, V. K. (2026) · Medicine in Drug Discovery · doi:10.1016/j.medidd.2026.100250

Novel AI-Optimized Nanoparticle-Mediated Gene Therapy for Targeted Revascularization and Limb Salvage in Gangrene: A Conceptual Framework with Mathematical Modeling, Simulation, and Sensitivity AnalysisPreprint

Shibah, S. R. M. (2026) · SSRN Electronic Journal · doi:10.2139/ssrn.6148849

Comparing the efficacy of nanocarriers for cutaneous and follicular delivery of poorly water-soluble molecules: A case study with ciclosporin A

Darade, A. R., Lapteva, M., & Kalia, Y. N. (2026) · International Journal of Pharmaceutics X · doi:10.1016/j.ijpx.2026.100505

Beyond the magic bullet: Programming delivery systems to overcome the antibody specificity paradox

Ma, Y., Zhou, Y., Xu, C., Gao, P., Gao, H., Luo, L., & Gao, X. (2026) · Journal of Controlled Release · doi:10.1016/j.jconrel.2026.114744

Recent Progress in Nanogel Technology: From Molecular Design to Biomedical Applications

Al-Ahmed, F. R., & Al-Lami, M. S. (2026) · Maaen Journal for Medical Sciences · doi:10.55810/2789-9136.1093

A dual QTOF–QTrap analytical platform for comprehensive tracking of doxycycline and its degradation byproducts in biological and nanoparticle-based delivery systems

Bofill-Bonet, C., Artigues, M., Moreno-Jiménez, I., Balà, N., Martorell, J., Fornaguera, C., & Borrós, S. (2026) · Talanta · doi:10.1016/j.talanta.2026.129754

Biocompatible nanosystems for innovative applications of small therapeutic molecules

Andreana, I. (2022) · doi:10.70675/dde2af37z7946z4047zb96bz1053d340e54f

Nanocarrier Technologies for Targeted Delivery

Tamuli, J., Devi, N., Tamuli, J., Patir, K., & Giri, S. (2026) · Advances in computational intelligence and robotics book series · doi:10.4018/979-8-3373-5268-8.ch008

3D Printing in Drug Delivery

Kumar, S., Mohanta, G. C., & Pandey, S. K. (2026) · Springer eBooks · doi:10.1007/978-981-95-6774-4_15

PLGA-PEG Nano-Adjuvant-Delivered ClfA Vaccine Elicits IL-17A-Mediated Neutrophil Activation to Confer Complete Protection Against Methicillin-Resistant Staphylococcus aureus

Shi, Z., Wan, Z., Tan, G., Xi, J., Cui, M., Hou, Y., Ma, Z., Sun, N., Zhu, Y., Li, M., et al. (2026) · International Journal of Nanomedicine · doi:10.2147/ijn.s592819

Systematic Design of PLGA Nanoparticles for Long-Acting Delivery of a Dual GLP-1/Glucagon Receptor Coagonist Peptide (SAR425899) via Phase Inversion Nanoencapsulation

Baptista, C., Milovanovic, K., Tatad, J., & Mathiowitz, E. (2026) · Langmuir · doi:10.1021/acs.langmuir.6c01535

Scalable diclofenac lauryl ester prodrug nanoparticles: a promising strategy for reducing inflammation associated with intervertebral disc degeneration

Hussain, S., Arif, A., Bano, P. B. P., Saleem, R., Rajput, S. N., Zhang, L., Khan, I., & Mujeeb-ur-Rehman (2026) · Drug Delivery and Translational Research · doi:10.1007/s13346-026-02172-z

Transforming stroke care: the promise of feedback-guided thrombolytic nanomedicine

Wang, Y., Wang, T. Q., Qu, X., Guo, L., Wang, Y., Yu, S., & Zhang, H. (2026) · Journal of Nanobiotechnology · doi:10.1186/s12951-026-04774-8

Optimizing PLGA nanosphere synthesis in a continuous ultrasonic microreactor: A design of experiments and machine learning joint approach

Chen, H., Bassim, O., Udepurkar, A. P., Sebastián, V., & Kuhn, S. (2026) · Chemical Engineering Journal · doi:10.1016/j.cej.2026.179818

Role of polymeric nanoparticles for the treatment of colon cancer

Rajput, D., Sharma, S., & Mishra, N. (2026) · Elsevier eBooks · doi:10.1016/b978-0-443-40443-6.00017-9

Platform Maturity and the NIH–Patent Nexus: Evidence from Polymer Drug-Delivery Research (2015–2025)Preprint

Hashemidehaghi, M., Omidi, Z., Toth, J. M., & Omidi, M. (2026) · Research Square · doi:10.21203/rs.3.rs-9684648/v1

Microenvironment‐Responsive Drug Delivery Systems for Ocular Surface Diseases: Mechanisms, Applications, and Translational Challenges

Liu, J., Chen, L., Fu, Y., & Zhang, S. (2026) · Small Science · doi:10.1002/smsc.70354

Engineered microorganisms and nanomaterials in cancer therapy: Emerging hybrid systems and translational challenges

Cheng, Y., 余申翰, Huang, Y., & Liu, B. (2026) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2026.103002

Nanoparticle Design at the Unstable Boundary between Physicochemical Control, Biological Adaptation, and Manufacturable Drug Delivery

Zhang, S., Yang, Z., Feng, L., & Huang, Y. (2025) · Pharmacophore · doi:10.51847/9pbrskyyb7

PLGA-based nanomedicines for cancer therapy: From synthesis and surface functionalization to clinical translation

Jameie, L., Abbaslou, D. M., Nategi, T., Keikhosrowkiani, N., Shahshahanipour, M., Sadeghi-Kaji, F.-S., Najafi, N., Bigham, A., & Rafienia, M. (2026) · Journal of Drug Delivery Science and Technology · doi:10.1016/j.jddst.2026.108828

Nanoparticle Platforms in Cancer Immunotherapy: A Critical Comparative Review of PLGA, Mesoporous Silica, Magnetic Nanoparticles, and Covalent Organic Frameworks

Niazi, S. K. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18081019

Nanoparticles: Small Interventions for Major Challenges in Aquaculture

González-Rodríguez, L., Pereiro, P., Novoa, B., & Figueras, A. J. (2026) · Biology · doi:10.3390/biology15161431

Mechanistic insights into additive-induced mechanical enhancement of 3D-Printed polymer composites- a multiscale review

Singh, G., Singh, G., & Singh, G. (2026) · Materials Chemistry and Physics · doi:10.1016/j.matchemphys.2026.133058

Bridging the Gap: Harnessing Phytochemical-Loaded Nanocarriers for Enhanced Epilepsy Treatment

Kazemi, M., Arab, F., Nasiri, A., Besharatiyan, F., & Jahani, R. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06147-6

Harnessing Medicinal Plants Through Advanced Drug Delivery: A New Era in Type 2 Diabetes Management

Dadhich, A., Sharma, V., Sharma, S., Bawari, S., & Sivanesan, I. (2026) · Pharmaceutics · doi:10.3390/pharmaceutics18091100

Nanomedicine Manufacturing Systems: Scale-Up Fragility, Reproducibility, and Quality Translation

Martins, B., Pereira, L., Azevedo, R., & Costa, P. (2025) · Journal of Applied Pharmaceutical Technologies and Systems · doi:10.68159/a764521438

Engineering nanomaterials for nanomedicine evolution: Progress, trends and translational challenges

Muhammad, S., Nabeel, M. I., Hameed, A., Joseph, C. G., Seemab, R., Ahmad, M., He, M., Zhao, Y., & Wang, J. (2026) · Next Materials · doi:10.1016/j.nxmate.2026.103307

Biocatalytic and biogenic pathways for sustainable nanoparticle synthesis: mechanisms, monitoring, and circular bioeconomy integration

Thakur, D., Kadu, P. K., Patel, V., Parkhe, V., & Kale, R. (2026) · Bioprocess and Biosystems Engineering · doi:10.1007/s00449-026-03418-3

Targeting the BACE1–GSK-3β Signaling Axis in Alzheimer’s Disease: From Molecular Crosstalk to Nanotechnology-Based Translational Strategies

Marimuthu, A., Singh, M. T., Balasubramanian, S., & Krishnamurthy, P. T. (2026) · Molecular Neurobiology · doi:10.1007/s12035-026-06203-1

Recent Advances in Polymeric Nanocarriers for Breast Cancer Drug Delivery

Amiryaghoubi, N., & Kim, B. S. (2026) · ACS Applied Nano Materials · doi:10.1021/acsanm.6c03941

Decoding the Influence of Polyvinyl Alcohol on the Functionalization and Cellular Uptake of Poly(lactic- co -glycolic) Acid Nanoparticles

Hameedat, F., Daware, R., Onori, I., Adamčík, J., Bazzoni, A., Lorenzi, F. D., Berrocal, J. A., Rothen‐Rutishauser, B., Petri‐Fink, A., Lammers, T., et al. (2026) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.6c00389

Emerging Frontiers of Biomedical Applications of PLGA : Where Do We Stand?

Gupta, D., Shah, D., & Suares, D. (2026) · Journal of Applied Polymer Science · doi:10.1002/app.71617

Nanostructured formulations of abiraterone and abiraterone acetate: therapeutic potential, pharmacokinetic considerations and bioanalytical perspectives

Fortunato, G. C., Duarte, J. L., Luiz, M. T., & Chorilli, M. (2026) · Therapeutic Delivery · doi:10.1080/20415990.2026.2742645

Industrial Scale Manufacturing and Downstream Processing of PLGA-Based Nanomedicines Suitable for Fully Continuous Operation

Operti, M. C., Bernhardt, A., Sincari, V., Jäger, E., Grimm, S., Engel, A., Hrubý, M., Figdor, C. G., & Tagit, O. (2022) · Pharmaceutics · doi:10.3390/pharmaceutics14020276 · Cited by 62

PLGA-Based Micro- and Nano-particles

Chaurasiya, A., Patra, P., Thathireddy, P., & Gorajiya, A. (2021) · CRC Press eBooks · doi:10.1201/9781003043164-6 · Cited by 1

Nanomedicine Formulations Based on PLGA Nanoparticles for Diagnosis, Monitoring and Treatment of Disease: From Bench to Bedside

Tagit, O. (2022) · MDPI eBooks · doi:10.3390/books978-3-0365-4489-2

Emerging Frontiers of Biomedical Applications of PLGA : Where Do We Stand?

Gupta, D., Shah, D., & Suares, D. (2026) · Journal of Applied Polymer Science · doi:10.1002/app.71617

Building the design, translation and development principles of polymeric nanomedicines using the case of clinically advanced poly(lactide(glycolide))–poly(ethylene glycol) nanotechnology as a model: An industrial viewpoint

Reddy, L. H., & Bazile, D. (2016) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2016.08.012 · Cited by 39