The DOI matches its Crossref record; 16 of the 16 references it cites were found in a registry or an index.
Radiation Dose–Volume Effects in Radiation-Induced Rectal Injury
Open accessAbstract
The available dose/volume/outcome data for rectal injury were reviewed. The volume of rectum receiving ≥60Gy is consistently associated with the risk of Grade ≥2 rectal toxicity or rectal bleeding. Parameters for the Lyman-Kutcher-Burman normal tissue complication probability model from four clinical series are remarkably consistent, suggesting that high doses are predominant in determining the risk of toxicity. The best overall estimates (95% confidence interval) of the Lyman-Kutcher-Burman model parameters are n = 0.09 (0.04–0.14); m = 0.13 (0.10–0.17); and TD50 = 76.9 (73.7–80.1) Gy. Most of the models of late radiation toxicity come from three-dimensional conformal radiotherapy dose-escalation studies of early-stage prostate cancer. It is possible that intensity-modulated radiotherapy or proton beam dose distributions require modification of these models because of the inherent differences in low and intermediate dose distributions.
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Cites
Cox, J. D., Stetz, J., & Pajak, T. F. (1995) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(95)00060-c · Cited by 4,792
Tolerance of normal tissue to therapeutic irradiation
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Wei, J. T., Dunn, R. L., Litwin, M. S., Sandler, H. M., & Sanda, M. G. (2000) · Urology · doi:10.1016/s0090-4295(00)00858-x · Cited by 1,520
Fitting of normal tissue tolerance data to an analytic function
Burman, C., Kutcher, G. J., Emami, B., & Goitein, M. (1991) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/0360-3016(91)90172-z · Cited by 1,249
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Zelefsky, M. J., Levin, E. J., Hunt, M., Yamada, Y., Shippy, A. M., Jackson, A., & Amols, H. I. (2008) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2007.11.044 · Cited by 735
Self-citationPeeters, S. T. H., Heemsbergen, W. D., van Putten, W. L. J., Slot, A., Tabak, H., Mens, J. W., Lebesque, J. V., & Koper, P. C. M. (2005) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2004.07.715 · Cited by 445
Jackson, A., Skwarchuk, M. W., Zelefsky, M. J., Cowen, D. M., Venkatraman, E. S., Levegrun, S., Burman, C. M., Kutcher, G. J., Fuks, Z., Liebel, S. A., et al. (2001) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(00)01414-0 · Cited by 342
Self-citationKing, C. R., Brooks, J. D., Gill, H. S., Pawlicki, T. A., Cotrutz, C., & Presti, J. C. (2008) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/j.ijrobp.2008.05.059 · Cited by 320
Late rectal toxicity: dose-volume effects of conformal radiotherapy for prostate cancer
Huang, E. H., Pollack, A., Levy, L., Starkschall, G., Dong, L., Rosen, I., & Kuban, D. A. (2002) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(02)03742-2 · Cited by 318
Cited by
Stewart, F. A., Akleyev, A. V., Hauer-Jensen, M., Hendry, J. H., Kleiman, N. J., MacVittie, T. J., Aleman, B. M., Edgar, A. B., Mabuchi, K., Muirhead, C. R., et al. (2012) · Annals of the ICRP · doi:10.1016/j.icrp.2012.02.001 · Cited by 1,604
Langendijk, J. A., Lambin, P., De Ruysscher, D., Widder, J., Bos, M., & Verheij, M. (2013) · Radiotherapy and Oncology · doi:10.1016/j.radonc.2013.05.007 · Cited by 549
Exploiting biological and physical determinants of radiotherapy toxicity to individualize treatment
Scaife, J. E., Barnett, G. C., Noble, D. J., Jena, R., Thomas, S. J., West, C. M. L., & Burnet, N. G. (2015) · The British Journal of Radiology · doi:10.1259/bjr.20150172 · Cited by 53
Metadata
- Authors
- Michalski, J. M., Gay, H., Jackson, A., Tucker, S. L., & Deasy, J. O.
- Venue
- International Journal of Radiation Oncology*Biology*Physics
- Publisher
- Elsevier BV
- Published
- 2010-03
- Volume
- 76
- Issue
- 3
- Pages
- S123-S129
- ISSN
- 0360-3016 (ISSN-L)
- OpenAlex
- W2012514380
- Cited by
- 718
- References
- 16
- FWCI
- 42.84
- Type
- journal article
- Language
- en
- Open access
- bronze
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