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Radiation Therapy to Convert the Tumor Into an In Situ Vaccine
Open accessAbstract
Over the past several months new examples of abscopal effects of radiotherapy have added to the existing literature on this subject, and demonstrated an association with an anti-tumor immune response (1–3). Initially met by understandable scepticism, our original hypothesis that the rare but repeatedly observed abscopal effect of radiation is, at least in part, immune-mediated is acquiring increasing support (4). Importantly, this new role of radiotherapy brings radiation oncology to the table of the “systemic disease modifiers”, a place it is generally excluded from.
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Cited by
Salgado, R., Denkert, C., Demaria, S., Sirtaine, N., Klauschen, F., Pruneri, G., Wienert, S., Van den Eynden, G., Baehner, F. L., Penault-Llorca, F., et al. (2015) · Annals of Oncology · doi:10.1093/annonc/mdu450 · Cited by 3,113
Self-citationShaverdian, N., Lisberg, A. E., Bornazyan, K., Veruttipong, D., Goldman, J. W., Formenti, S. C., Garon, E. B., & Lee, P. (2017) · The Lancet Oncology · doi:10.1016/s1470-2045(17)30380-7 · Cited by 1,091
Self-citationCancer nanomedicine for combination cancer immunotherapy
Nam, J., Son, S., Park, K. S., Zou, W., Shea, L. D., & Moon, J. J. (2019) · Nature Reviews Materials · doi:10.1038/s41578-019-0108-1 · Cited by 940
Consensus guidelines for the detection of immunogenic cell death
Kepp, O., Senovilla, L., Vitale, I., Vacchelli, E., Adjemian, S., Agostinis, P., Apetoh, L., Aranda, F., Barnaba, V., Bloy, N., et al. (2014) · OncoImmunology · doi:10.4161/21624011.2014.955691 · Cited by 832
Self-citationOpportunities and challenges of radiotherapy for treating cancer
Schaue, D., & McBride, W. H. (2015) · Nature Reviews Clinical Oncology · doi:10.1038/nrclinonc.2015.120 · Cited by 784
Metadata
- Authors
- Formenti, S. C., & Demaria, S.
- Venue
- International Journal of Radiation Oncology*Biology*Physics
- Publisher
- Elsevier BV
- Published
- 2012-11
- Volume
- 84
- Issue
- 4
- Pages
- 879-880
- ISSN
- 0360-3016 (ISSN-L)
- OpenAlex
- W2075879891
- Cited by
- 319
- References
- 0
- FWCI
- 4.56
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Formenti, S. C., & Demaria, S. (2012). Radiation Therapy to Convert the Tumor Into an In Situ Vaccine. International Journal of Radiation Oncology*Biology*Physics. https://doi.org/10.1016/j.ijrobp.2012.06.020
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
