Tumor-Associated Macrophages: From Mechanisms to Therapy

Noy, Roy, Pollard, Jeffrey W.·2014·Immunity

DOI 10.1016/j.immuni.2014.06.010

Cited by (1,010)

Items 501–600 of 1,010

An Orally Active Galectin-3 Antagonist Inhibits Lung Adenocarcinoma Growth and Augments Response to PD-L1 Blockade
Lynda H. Vuong, Eleni Kouverianou, Claire M. Rooney, Brian J. McHugh, Sarah Howie, Christopher D. Gregory, Stuart John Forbes, Neil Cowan Henderson, Fredrik R. Zetterberg, Ulf J. Nilsson et al. · 2019 · Cancer Research
Tumour microenvironment responsive nanoconstructs for cancer theranostic
Arif Gulzar, Jiating Xu, Chen Wang, Fei He, Dan Yang, Shili Gai, Piaoping Yang, Jun Lin, Dayong Jin, Bengang Xing · 2019 · Nano Today
Hypoxia-induced ZEB1 promotes cervical cancer progression via CCL8-dependent tumour-associated macrophage recruitment
Xiao-Jing Chen, Yuan-Run Deng, Zi‐Ci Wang, Wen-Fei Wei, Chen-Fei Zhou, Yanmei Zhang, Rui-Ming Yan, Luo-Jiao Liang, Mei Zhong, Liang Li et al. · 2019 · Cell Death and Disease
Targeting CXCR4-dependent immunosuppressive Ly6C low monocytes improves antiangiogenic therapy in colorectal cancer
Jung, Keehoon, Heishi, Takahiro, Incio, Joao, Huang, Yuhui, Beech, Elizabeth Y., Pinter, Matthias, Ho, William W., Kawaguchi, Kosuke, Rahbari, Nuh N., Chung, Euiheon et al. · 2017 · Proceedings of the National Academy of Sciences
Astrocytic trans-Differentiation Completes a Multicellular Paracrine Feedback Loop Required for Medulloblastoma Tumor Growth
Maojin Yao, Patrick B. Ventura, Ying Jiang, Fausto J. Rodriguez, Lixin Wang, Justin S. A. Perry, Yibo Yang, Kelsey Wahl, Rowena B. Crittenden, Mariko L. Bennett et al. · 2020 · Cell
Combinational Immunotherapy for Hepatocellular Carcinoma: Radiotherapy, Immune Checkpoint Blockade and Beyond
Yun Hua Lee, David Wai-Meng Tai, Connie Yip, Su Pin Choo, Valerie Chew · 2020 · Frontiers in Immunology
Precise modulation and use of reactive oxygen species for immunotherapy
Xinyan Li, Jingjing Gao, Chengcheng Wu, Chaoyu Wang, Ruoshi Zhang, Jia He, Ziting Judy Xia, Nitin Joshi, Jeffrey M. Karp, Rui Kuai · 2024 · Science Advances
Prognostic and predictive value of tumor-infiltrating lymphocytes in breast cancer: a systematic review and meta-analysis
Xiaoming Yu, Zhigang Zhang, Zhuhao Wang, Pin Wu, Fuming Qiu, Jiacheng Huang · 2015 · Clinical & Translational Oncology
The macrophage tetraspan MS4A4A enhances dectin-1-dependent NK cell–mediated resistance to metastasis
Irene Mattiola, Federica Tomay, Maria De Pizzol, Rita Silva-Gomes, Benedetta Savino, Tamara Gulić, Andrea Doni, Silvia Lonardi, Marie‐Astrid Boutet, Alessandra Nerviani et al. · 2019 · Nature Immunology
Tumor-associated macrophages: A promising target for a cancer immunotherapeutic strategy
Siyu Zhang, Xinyu Song, Li Yang, Linlin Ye, Qiong Zhou, Wei-Bing Yang · 2020 · Pharmacological Research
Leukocyte-mediated Delivery of Nanotherapeutics in Inflammatory and Tumor Sites
Xinyue Dong, Dafeng Chu, Zhenjia Wang · 2017 · Theranostics
Peptide-guided resiquimod-loaded lignin nanoparticles convert tumor-associated macrophages from M2 to M1 phenotype for enhanced chemotherapy
Patrícia Figueiredo, Anni Lepland, Pablo Scodeller, Flavia Fontana, Giulia Torrieri, Mattia Tiboni, Mohammad‐Ali Shahbazi, Luca Casettari, Mauri A. Kostiainen, Jouni J. Hirvonen et al. · 2020 · Acta Biomaterialia
Emerging strategies in targeting tumor-resident myeloid cells for cancer immunotherapy
Yi Wang, Kai Conrad Cecil Johnson, Margaret Elena Gatti-Mays, Zihai Li · 2022 · Journal of Hematology & Oncology
Extracellular vesicles and particles impact the systemic landscape of cancer
Serena Lucotti, Candia M. Kenific, Haiying Zhang, David C. Lyden · 2022 · The EMBO Journal
The m6A Reader IGF2BP2 Regulates Macrophage Phenotypic Activation and Inflammatory Diseases by Stabilizing TSC1 and PPAR γ
Wang, Xia, Ji, Yuge, Feng, Panpan, Liu, Rucheng, Li, Guosheng, Zheng, Junjie, Xue, Yaqiang, Wei, Yaxun, Ji, Chunyan, Chen, Dawei et al. · 2021 · Advanced Science
Systemic Treatment Options in Hepatocellular Carcinoma
Lorenza Rimassa, Tiziana Pressiani, Philippe Merle · 2019 · Liver Cancer
MCT4 blockade increases the efficacy of immune checkpoint blockade
Nathalie Babl, Sonja-Maria Decking, Florian Voll, Michael Althammer, Ada Sala-Hojman, Roberta Ferretti, Clarissa Korf, Christian Schmidl, Lisa Schmidleithner, Benedikt Nerb et al. · 2023 · Journal for ImmunoTherapy of Cancer
Balancing the innate immune system in tumor development
Catharina Hagerling, Amy-Jo Casbon, Zena Werb · 2014 · Trends in Cell Biology
Next frontier in tumor immunotherapy: macrophage-mediated immune evasion
Yingqi Qiu, Tong Chen, Rong Hu, Ruiyi Zhu, Chujun Li, Yingchen Ruan, Xiaoling Xie, Yuhua Li · 2021 · Biomarker Research
Natural Coevolution of Tumor and Immunoenvironment in Glioblastoma
Lingxiang Wu, Wei Wu, Junxia Zhang, Zheng Zhao, Liangyu Li, Mengyan Zhu, Min Wu, Fan Wu, Fengqi Zhou, Yuxin Du et al. · 2022 · Cancer Discovery
Control of tumor-associated macrophage responses by nutrient acquisition and metabolism
Xian Zhang, Liangliang Ji, Ming O. Li · 2023 · Immunity
Multifaceted role of redox pattern in the tumor immune microenvironment regarding autophagy and apoptosis
Yuqing Ren, Ruizhi Wang, Siyuan Weng, Hui Xu, Yuyuan Zhang, Shuang Chen, Shutong Liu, Yuhao Ba, Zhaokai Zhou, Peng Luo et al. · 2023 · Molecular Cancer
Chronic inflammation and cancer; the two sides of a coin
Queenie Fernandes, Varghese Philipose Inchakalody, Takwa Bedhiafi, Sarra Mestiri, Nassiba Taib, Shahab Uddin M.S., Maysaloun Merhi, Said Dermime · 2023 · Life Sciences
Predicting prognosis and therapeutic response from interactions between lymphocytes and tumor cells
David Alan Quigley, Vessela N. Kristensen · 2015 · Molecular Oncology
Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis
Tamara Muliaditan, Jonathan Caron, Mary Okesola, James W. Opzoomer, Paris Kosti, Mirella Georgouli, Peter Gordon, Sharanpreet Kall Lall, Desislava M. Kuzeva, Luísa Pedro et al. · 2018 · Nature Communications
Tumor-associated macrophages modulate resistance to oxaliplatin via inducing autophagy in hepatocellular carcinoma
Xiu-Tao Fu, Kang Song, Jian Zhou, Ying-Hong Shi, Wei-Ren Liu, Guo‐Ming Shi, Qiang Gao, Xiao-Ying Wang, Zhen-Bin Ding, Jia Fan · 2019 · Cancer Cell International
Ferroptosis of immune cells in the tumor microenvironment
Rina Kim, Devon K. Taylor, Robert H. Vonderheide, Dmitry I. Gabrilovich · 2023 · Trends in Pharmacological Sciences
Inflammatory Monocytes Promote Perineural Invasion via CCL2-Mediated Recruitment and Cathepsin B Expression
Richard Lorne Bakst, Huizhong Xiong, Chun‐Hao Chen, Sylvie Deborde, Anna Lyubchik, Yi Zhou, Shizhi He, William A. McNamara, Sei‐Young Lee, Oakley C. Olson et al. · 2017 · Cancer Research
Tunneling nanotubes, a novel mode of tumor cell–macrophage communication in tumor cell invasion
Samer J. Hanna, Kessler McCoy-Simandle, Edison Leung, Alessandro Genna, John S. Condeelis, Dianne Cox · 2019 · Journal of Cell Science
Magnetic Particle Imaging: Current Applications in Biomedical Research
Nazanin Talebloo, Mithil Gudi, Neil Robertson, Ping Wang · 2019 · Journal of Magnetic Resonance Imaging
Vaccine-like nanomedicine for cancer immunotherapy
Yunfei Yi, Mian Yu, Wen Li, Dunwan Zhu, Lin Mei, Meitong Ou · 2023 · Journal of Controlled Release
Novel Mechanism of Macrophage-Mediated Metastasis Revealed in a Zebrafish Model of Tumor Development
Jian Wang, Ziquan Cao, Xing‐Mei Zhang, Masaki Nakamura, Meili Sun, Johan Hartman, Robert Adam Harris, Yuping Sun, Yihai Cao · 2014 · Cancer Research
TAM Family Receptor Kinase Inhibition Reverses MDSC-Mediated Suppression and Augments Anti–PD-1 Therapy in Melanoma
Alisha Holtzhausen, William P. Harris, Eric Ubil, Debra M. Hunter, Jichen Zhao, Yuewei Zhang, Dehui� Zhang, Qingyang Liu, Xiaodong Wang, Douglas K. Graham et al. · 2019 · Cancer Immunology Research
Tumor-Derived Prostaglandin E2 Promotes p50 NF-κB-Dependent Differentiation of Monocytic MDSCs
Chiara Porta, Francesca Maria Consonni, Sara Morlacchi, Sabina Sangaletti, Augusto Bleve, Maria Grazia Totaro, Paola Larghi, Monica Rimoldi, Claudio Tripodo, Laura Strauss et al. · 2020 · Cancer Research
Recent Advances and Challenges in Cancer Immunotherapy
Chelsea M. Peterson, Nathan Denlinger, Yiping Yang · 2022 · Cancers
Macrophage activation in human diseases
Joachim Ludwig Schultze, Astrid Schmieder, Sergij Goerdt · 2015 · Seminars in Immunology
Pharmacological macrophage inhibition decreases metastasis formation in a genetic model of pancreatic cancer
Heidi Griesmann, Christof Drexel, Nada Milosevic, Bence Sipos, Jonas Rosendahl, Thomas Mathias Gress, Patrick Michl · 2016 · Gut
Primary M1 macrophages as multifunctional carrier combined with PLGA nanoparticle delivering anticancer drug for efficient glioma therapy
Liang Pang, Ying Zhu, Jing Qin, Wenjie Zhao, Jianxin Wang · 2018 · Drug Delivery
Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade
Mohammad Rashidian, Martin W. LaFleur, Vincent L. Verschoor, Anushka Dongre, Yun Zhang, Thao H. Nguyen, Stephen C. Kolifrath, Amir Reza Aref, Christie J. Lau, Cloud Peter Paweletz et al. · 2019 · Proceedings of the National Academy of Sciences
Chemotherapy resistance in epithelial ovarian cancer: Mechanisms and emerging treatments
Marchetti, Claudia, De Felice, Francesca, Romito, Alessia, Iacobelli, Valentina, Sassu, Carolina Maria, Corrado, Giacomo, Ricci, Caterina, Scambia, Giovanni, Fagotti, Anna · 2021 · Seminars in Cancer Biology
Tumor-associated microglia and macrophages in glioblastoma: From basic insights to therapeutic opportunities
Guoqing Wang, Kunhong Zhong, Zeng Wang, Zongliang Zhang, Xin Tang, Aiping Tong, Liangxue Zhou · 2022 · Frontiers in Immunology
Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment
Ruiwen Ruan, Li Li, Xuan Li, Chunye Huang, Zhang Zhanmin, Hongguang Zhong, Shaocheng Zeng, Qianqian Shi, Xia Yang, Qinru Zeng et al. · 2023 · Molecular Cancer
Regulatory B cells contribute to the impaired antitumor immunity in ovarian cancer patients
Xin Lan Wei, Yangqiu Jin, Yinpu Tian, Huiyuan Zhang, Jie Wu, Wei Lü, Xiaofen Lu · 2015 · Tumor Biology
Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases
Colleen M. McClean, David M. Tobin · 2016 · Pathogens and Disease
Macrophage biology plays a central role during ionizing radiation-elicited tumor response
Qiuji Wu, Awatef Allouch, Isabelle Martins, Nazanine Modjtahedi, Éric Deutsch, Jean‐Luc Perfettini · 2017 · Biomedical Journal
Low tumor purity is associated with poor prognosis, heavy mutation burden, and intense immune phenotype in colon cancer
Yihao Mao, Qingyang Feng, Peng Zheng, Liangliang Yang, Tianyu Liu, Yuqiu Xu, Dexiang Zhu, Wenju Chang, Meiling Ji, Li Ren et al. · 2018 · Cancer Management and Research
Circulating tumor cells in cancer patients: developments and clinical applications for immunotherapy
Xiaoming Zhong, Hang-Tian Zhang, Ying Zhu, Yuqing Liang, Zhuolin Yuan, Jing Li, Xin Li, Xin Li, Yifan Jia, He Tian et al. · 2020 · Molecular Cancer
Modulation of tumor microenvironment for immunotherapy: focus on nanomaterial-based strategies
Yun Liu, Jianfeng Guo, Leaf Huang · 2020 · Theranostics
NK cell exhaustion in the tumor microenvironment
Jia Hao, Hongmei Yang, Huaxing Xiong, Kathy Qian Luo · 2023 · Frontiers in Immunology
Nasopharyngeal carcinoma: current views on the tumor microenvironment's impact on drug resistance and clinical outcomes
Huai Liu, Ling Yin Tang, Yanxian Li, Wenji Xie, Ling Zhang, Hailin Tang, Tengfei Xiao, Hongmin Yang, Wangning Gu, Hui Wang et al. · 2024 · Molecular Cancer
A prodrug of green tea polyphenol (–)-epigallocatechin-3-gallate (Pro-EGCG) serves as a novel angiogenesis inhibitor in endometrial cancer
Wang, Jianzhang, Man, Gene Chi Wai, Chan, Tak Hang, Kwong, Joseph, Wang, Chi Chiu · 2018 · Cancer Letters
Optimizing Tumor Microenvironment for Cancer Immunotherapy: β-Glucan-Based Nanoparticles
Mei Zhang, Julian A. Kim, Alex Yee-Chen Huang · 2018 · Frontiers in Immunology
TGF-β1 secreted by M2 phenotype macrophages enhances the stemness and migration of glioma�cells via the SMAD2/3 signalling pathway
Zhengzheng Liu, Weilu Kuang, Qin Zhou, Yingying Zhang · 2018 · International Journal of Molecular Medicine
Scaffolds biomimicking macrophages for a glioblastoma NIR-Ib imaging guided photothermal therapeutic strategy by crossing Blood-Brain Barrier
Jiazheng Lai, Guanjun Deng, Zhihong Sun, Xinghua Peng, Jing Li, Ping Gong, Pengfei Zhang, Lintao Cai · 2019 · Biomaterials
CSF-1/CSF-1R targeting agents in clinical development for cancer therapy
Carola Hermine Ries, Sabine Hoves, Michael A. Cannarile, Dominik Rüttinger · 2015 · Current Opinion in Pharmacology
MiRNAs: dynamic regulators of immune cell functions in inflammation and cancer
Simon Hirschberger, Ludwig Christian Hinske, Simone Kreth · 2018 · Cancer Letters
Recruitment of CCR2 + tumor associated macrophage to sites of liver metastasis confers a poor prognosis in human colorectal cancer
Julie G. Grossman, Timothy M. Nywening, Brian A. Belt, Roheena Z. Panni, Bradley Aaron Krasnick, David G. DeNardo, William G. Hawkins, Simon Peter Goedegebuure, David C. Linehan, Ryan Courtney Fields · 2018 · OncoImmunology
Recent Advances in Macrophage-Mediated Drug Delivery Systems
Liang, Tiantian, Zhang, Rongtao, Liu, Xianbin, Ding, Qian, Wu, Siqiong, Li, Chunhong, Lin, Yan, Ye, Yun, Zhong, Zhirong, Zhou, Meiling · 2021 · International Journal of Nanomedicine
New Approaches on Cancer Immunotherapy
Jong‐Ho Cha, Li-Chuan Chan, Min Sup Song, Mien‐Chie Hung · 2019 · Cold Spring Harbor Perspectives in Medicine
Tumor-associated macrophages and anti-tumor therapies: complex links
Cristina Belgiovine, Maurizio D’Incalci, Paola Allavena, Roberta Frapolli · 2016 · Cellular and Molecular Life Sciences
The pro-inflammatory role of platelets in cancer
Anna‐Karin Olsson, Jessica Cedervall · 2018 · Platelets
Interstitial flow promotes macrophage polarization toward an M2 phenotype
Ran Li, Jean Carlos Serrano, Hao Xing, Tara A. Lee, Hesham Azizgolshani, Muhammad Hamid Zaman, Roger Dale Kamm · 2018 · Molecular Biology of the Cell
GATA3 as a master regulator for interactions of tumor-associated macrophages with high-grade serous ovarian carcinoma
Amr Ahmed El‐Arabey, Merve Denizli, Pınar Kanlikilicer, Recep Bayraktar, Cristina Ivan, Mohammed Helmy Rashed, Nashwa N. Kabil, Bülent Özpolat, George Adrian Calin, Salama Abdou Salama et al. · 2020 · Cellular Signalling
CXCL8 in Tumor Biology and Its Implications for Clinical Translation
Xingyu Xiong, Xinyang Liao, Shi Qiu, Hang Xu, Shiyu Zhang, Sheng Wang, Jianzhong Ai, Lu Yang · 2022 · Frontiers in Molecular Biosciences
MHC class II-restricted antigen presentation is required to prevent dysfunction of cytotoxic T cells by blood-borne myeloids in brain tumors
Michael Kilian, Ron Sheinin, Chin Leng Tan, Mirco Friedrich, Christopher Krämer, Ayelet Kaminitz, Khwab Sanghvi, Katharina A.M. Lindner, Yu‐Chan Chih, Frederik Cichon et al. · 2023 · Cancer Cell
Signaling by Extracellular Vesicles Advances Cancer Hallmarks
Masamitsu Kanada, Michael H. Bachmann, Christopher H. Contag · 2016 · Trends in cancer
Targeted gene silencing of CCL2 inhibits triple negative breast cancer progression by blocking cancer stem cell renewal and M2 macrophage recruitment
Wei Bin Fang, Min Yao, Gage Brummer, Diana Acevedo, Nabil A. Alhakamy, Cory J. Berkland, Nikki Cheng · 2016 · Oncotarget
Peripheral blood clinical laboratory variables associated with outcomes following combination nivolumab and ipilimumab immunotherapy in melanoma
Samuel Rosner, Erica Kwong, Alexander Noor Shoushtari, Claire Frances Friedman, Allison Betof Warner, Mary Sue Brady, Daniel G. Coit, Margaret K. Callahan, Jedd D. Wolchok, Paul B. Chapman et al. · 2018 · Cancer Medicine
Astrocyte immunometabolic regulation of the tumour microenvironment drives glioblastoma pathogenicity
Rita Perelroizen, Bar Philosof, Noga Budick-Harmelin, Tom Chernobylsky, Ariel Ron, Rotem Katzir, Dor Shimon, Adi Tessler, Orit Adir, Anat Gaoni-Yogev et al. · 2022 · Brain
Inflammation as target in cancer therapy
Giulia Marelli, Antonio Sica, Luca E. Vannucci, Paola Allavena · 2017 · Current Opinion in Pharmacology
Specialized immune responses in the peritoneal cavity and omentum
Mingyong Liu, Aarón Silva-Sánchez, Troy D. Randall, Selene Meza‐Perez · 2020 · Journal of Leukocyte Biology
Very low mutation burden is a feature of inflamed recurrent glioblastomas responsive to cancer immunotherapy
Matthias Gromeier, Michael C. Brown, Gao Zhang, Xiang Lin, Yeqing Chen, Zhi Wei, Nike T. Beaubier, Hai Yan, Yiping He, Annick Desjardins et al. · 2021 · Nature Communications
Elevated protein lactylation promotes immunosuppressive microenvironment and therapeutic resistance in pancreatic ductal adenocarcinoma
Kang Sun, Xiaozhen Zhang, Jiatao Shi, Jinyan Huang, Sicheng Wang, Xiang Li, Haixiang Lin, Danyang Zhao, Mao Ye, Sirui Zhang et al. · 2025 · Journal of Clinical Investigation
Controlled release of cytokines using silk-biomaterials for macrophage polarization
Reeves, Andrew R.D., Spiller, Kara L., Freytes, Donald O., Vunjak-Novakovic, Gordana, Kaplan, David L. · 2015 · Biomaterials
Why Target Immune Cells for Plasma Treatment of Cancer
Vandana Miller, Abraham G. Lin, Alexander Fridman · 2015 · Plasma Chemistry and Plasma Processing
Nanoparticles for tumor immunotherapy
Xinlong Zang, Xiuli Zhao, Haiyang Hu, Mingxi Qiao, Yihui Deng, Dawei Chen · 2017 · European Journal of Pharmaceutics and Biopharmaceutics
Limitations of Anti-Angiogenic Treatment of Tumors
Doménico Ribatti, Tiziana Annese, Simona Ruggieri, Roberto Tamma, Enrico Crivellato · 2019 · Translational Oncology
Securing the Payload, Finding the Cell, and Avoiding the Endosome: Peptide‐Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA
Byungji Kim, Si Sun, Judith A. Varner, Stephen B. Howell, Erkki I. Ruoslahti, Michael J. Sailor · 2019 · Advanced Materials
Macrophage-targeted nanomedicine for chronic diseases immunotherapy
Yuejia Song, Yaqian Huang, Fang Zhou, Jinsong Ding, Wenhu Zhou · 2021 · Chinese Chemical Letters
Predictive value of lymphocyte-to-monocyte ratio in the preoperative setting for progression of patients with breast cancer
Wataru Goto, Shinichiro Kashiwagi, Yuka Asano, Koji Takada, Katsuyuki Takahashi, Takaharu Hatano, Tsutomu Takashima, Shuhei Tomita, Hisashi Motomura, Kosei Hirakawa et al. · 2018 · BMC Cancer
Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer
Payal Tiwari, Ariane Blank, Chang Cui, Kelly Q. Schoenfelt, Guolin Zhou, Yanfei Xu, Galina F. Khramtsova, Olufunmilayo Ibironke Olopade, Ajay M. Shah, Seema Ahsan Khan et al. · 2019 · The Journal of Experimental Medicine
Targeting tumor-associated macrophages for cancer immunotherapy
Yongheng Shu, Ping Cheng · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation
Jessica A. Mills, Feifei Liu, Thomas Ryan Jarrett, Nicholas L. Fletcher, Kristofer J. Thurecht · 2022 · Biomaterials Science
Distinct functions of macrophage-derived and cancer cell-derived cathepsin Z combine to promote tumor malignancy via interactions with the extracellular matrix
Leila Akkari, Vasilena Gocheva, Jemila C. Kester, Karen E. Hunter, Marsha L. Quick, Lisa Sevenich, Hao‐Wei Wang, Christoph Peters, Laura H. Tang, David S. Klimstra et al. · 2014 · Genes & Development
Collagen Density Modulates the Immunosuppressive Functions of Macrophages
Anne Mette H. Larsen, Dorota Ewa Kuczek, Adrija Kalviša, Majken Storm Siersbæk, Marie‐Louise Thorseth, Astrid Zedlitz Johansen, Marco Carretta, Lars Grøntved, Ole Vang, Daniel Hargbøll Madsen · 2020 · The Journal of Immunology
Tumor-Associated Neutrophils and Macrophages—Heterogenous but Not Chaotic
Ling Wu, Xiang H.-F. Zhang · 2020 · Frontiers in Immunology
PD-L1 immunohistochemistry for canine cancers and clinical benefit of anti-PD-L1 antibody in dogs with pulmonary metastatic oral malignant melanoma
Naoya Maekawa, Satoru Konnai, Maki Nishimura, Yumiko Kagawa, Satoshi Takagi, Kenji Hosoya, Hiroshi Ohta, Sangho Kim, Tomohiro Okagawa, Yusuke Izumi et al. · 2021 · npj Precision Oncology
DKK1 Promotes Tumor Immune Evasion and Impedes Anti–PD-1 Treatment by Inducing Immunosuppressive Macrophages in Gastric Cancer
Tao Shi, Yipeng Zhang, Yue Wang, Xueru Song, Hanbing Wang, Xiaoyu Zhou, Kaijie Liang, Yuting Luo, Keying Che, Xuan Wang et al. · 2022 · Cancer Immunology Research
Origin and functions of pro-inflammatory cytokine producing Foxp3+ regulatory T cells
Pushpa Pandiyan, Jinfang Zhu · 2015 · Cytokine
Integrin αvβ8–expressing tumor cells evade host immunity by regulating TGF-β activation in immune cells
Takasaka, Naoki, Seed, Robert I., Cormier, Anthony, Bondesson, Andrew J., Lou, Jianlong, Elattma, Ahmed, Ito, Saburo, Yanagisawa, Haruhiko, Hashimoto, Mitsuo, Ma, Royce et al. · 2018 · JCI Insight
PKB/Akt-dependent regulation of inflammation in cancer
Fengyuan Tang, Yuhua Wang, Brian A. Hemmings, Curzio Rüegg, Gongda Xue · 2017 · Seminars in Cancer Biology
Noncanonical Pathway for Regulation of CCL2 Expression by an mTORC1-FOXK1 Axis Promotes Recruitment of Tumor-Associated Macrophages
Hirokazu Nakatsumi, Masaki Matsumoto, Keiichi I. Nakayama · 2017 · Cell Reports
Targeting tumor-associated macrophages in hepatocellular carcinoma: biology, strategy, and immunotherapy
Hongyu Zheng, Xueqiang Peng, Shuo Yang, Xinyu Li, Mingyao Huang, Shibo Wei, Sheng Zhang, Guangpeng He, Jiaxing Liu, Qing Fan et al. · 2023 · Cell Death Discovery
Dual mRNA co-delivery for in situ generation of phagocytosis-enhanced CAR macrophages augments hepatocellular carcinoma immunotherapy
Zhenmei Yang, Ying Liu, Kun Zhao, Weiqiang Jing, Lin Gao, Xianghui Dong, Yan Wang, Maosen Han, Chongdeng Shi, Chunwei Tang et al. · 2023 · Journal of Controlled Release
Transcriptional and metabolic reprogramming induce an inflammatory phenotype in non-medullary thyroid carcinoma-induced macrophages
Rob J.W. Arts, Theo S. Plantinga, Sander Tuit, Thomas Ulas, Bas Heinhuis, Marika H. Tesselaar, Yvette J. E. Sloot, Gosse J. Adema, Leo A. B. Joosten, Johannes W. A. Smit et al. · 2016 · OncoImmunology
Inflammatory monocytes hinder antiviral B cell responses
Stefano Sammicheli, Mirela Kuka, Pietro Di Lucia, Nereida Jiménez de Oya, Marco De Giovanni, Jessica Fioravanti, Claudia Cristofani, Carmela G. Maganuco, Bénédict Fallet, Lucia Ganzer et al. · 2016 · Science Immunology
The Prognostic and Clinicopathological Significance of Tumor-Associated Macrophages in Patients with Gastric Cancer: A Meta-Analysis
Songcheng Yin, Jinyu Huang, Zhan Li, Junyan Zhang, Jiazi Luo, Chunyang Lu, Hao Xu, Huimian Xu · 2017 · PLoS ONE
Oncolytic viruses: overcoming translational challenges
Jordi Martínez‐Quintanilla, Ivan Yu Jun Seah, Melissa Ming Jie Chua, Khalid Shah · 2019 · Journal of Clinical Investigation
CEACAM1 as a Multi-Purpose Target for Cancer Immunotherapy
Matthew Dankner, Scott D. Gray‐Owen, Yu‐Hwa Huang, Richard S. Blumberg, Nicole Beauchemin · 2017 · OncoImmunology
Tumor-Associated Macrophages: Therapeutic Targets for Skin Cancer
Taku Fujimura, Yumi Kambayashi, Yasuhiro Fujisawa, Takanori Hidaka, Setsuya Aiba · 2018 · Frontiers in Oncology