The P2X7 Receptor in Infection and Inflammation

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1. Z1456467176 alleviates gouty arthritis by allosterically modulating P2X7R to inhibit NLRP3 inflammasome activation
   Xiaoling Li, Yiming Liu, Chengyu Luo, Jin‐Hui Tao · 2022 · Frontiers in Pharmacology
2. Synthetic molecules as P2X7 receptor antagonists: A medicinal chemistry update focusing the therapy of inflammatory diseases
   João Carlos Martins Mafra, Núbia Boechat, Guilherme Pegas Teixeira, Robson Xavier Faria · 2023 · European Journal of Pharmacology
3. Flavonoid extracted from Epimedium attenuate cGAS‐STING‐mediated diseases by targeting the formation of functional STING signalosome
   Yan Wang, Guang Xu, Jincai Wen, Xiaomei Zhao, Huanying Zhao, Gui-Ji Lv, Yingjie Xu, Xiu Ye, Junjie Li, Simin Chen et al. · 2024 · Immunology
4. TSPO deficiency exacerbates acute lung injury via NLRP3 inflammasome-mediated pyroptosis
   Jingyi Han, Xue Zhang, Menghua Cai, Feng Tian, Yi Xu, Hui Chen, Wei He, Jianmin Zhang, Hui Tian · 2024 · Chinese Medical Journal
5. The impacts of obesity in rheumatoid arthritis and insights into therapeutic purinergic modulation
   Geórgia de Carvalho Braga, Júlia Leão Batista Simões, Yara Juarez Teixeira dos Santos, João Carlos Menta Filho, Margarete Dulce Bagatini · 2024 · International Immunopharmacology
6. The potential role of purinergic signaling in cancer therapy: perspectives on anti-CD73 strategies for prostate cancer
   Carla Fernanda Furtado Gardani, Fernando Mendonça Diz, Luísa Brandalise Dondé, Liliana Rockenbach, Stefan Laufer, Fernanda Bueno Morrone · 2024 · Frontiers in Immunology
7. Selective regulation of IFN-γ and IL-4 co-producing unconventional T cells by purinergic signaling
   Calvin Xu, Andreas Obers, Minyi Qin, Alice Brandli, Joelyn Wong, Xin Huang, Allison Clatch, A. Fayed, Graham Starkey, Rohit D'Costa et al. · 2024 · Journal of Experimental Medicine
8. Moringa oleifera modulates cholinergic and purinergic enzymes activity in BV-2 microglial cells
   Stephen Adeniyi Adefegha, Charles Elias Assmann, Maria Rosa Chitolina Schetinger, Cínthia Melazzo de Andrade, Tatiana Emanuelli · 2021 · Metabolic Brain Disease
9. Discovery of bilirubin as novel P2X7R antagonist with anti-tumor activity
   Yunshuo Zhao, Xiaotong Chen, Chuanjie He, Guanfei Gao, Zhenzhen Chen, Jiangfeng Du · 2021 · Bioorganic & Medicinal Chemistry Letters
10. Pannexin 1-Mediated ATP Signaling in the Trigeminal Spinal Subnucleus Caudalis Is Involved in Tongue Cancer Pain
    Ryo Koyama, Koichi Iwata, Yoshinori Hayashi, Suzuro Hitomi, Ikuko Shibuta, Akihiko Furukawa, Sayaka Asano, Tadayoshi Kaneko, Yoshiyuki Yonehara, Masamichi Shinoda · 2021 · International Journal of Molecular Sciences
11. Targeting innate immune responses to attenuate acetaminophen-induced hepatotoxicity
    Jincheng Wang, Lulu Zhang, Qi Wu Shi, Bo Yang, Qiaojun He, Jiajia Wang, Qinjie Weng · 2022 · Biochemical Pharmacology
12. P2X7 receptor blockade decreases inflammation, apoptosis, and enteric neuron loss during Clostridioides difficile toxin A-induced ileitis in mice
    Ana A Q A Santos, Deiziane Viana da Silva Costa, Danielle Abreu Foschetti, Antoniella Souza Gomes Duarte, Conceição S Martins, Pedro Marcos Gomes Soares, Patrícia Castelucci, Gerly Anne de Castro Brito · 2022 · World Journal of Gastroenterology
13. The role of the P2X7 receptor in myeloid-derived suppressor cells and immunosuppression
    Elisa Principi, Lizzia Raffaghello · 2019 · Current Opinion in Pharmacology
14. P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice
    Giorgia Conte, Thanh Ngoc Nguyen, Mariana Alves, Laura de Diego-García, Aidan Kenny, Annette Nicke, David Clifford Henshall, Eva Maria Jimenez-Mateos, Tobías Engel · 2020 · Frontiers in Molecular Neuroscience
15. Extracellular Adenosine Triphosphate (eATP) and Its Metabolite, Extracellular Adenosine (eAdo), as Opposing “Yin–Yang” Regulators of Nlrp3 Inflammasome in the Trafficking of Hematopoietic Stem/Progenitor Cells
    Mariusz Z. Ratajczak, Magda Kucia · 2021 · Frontiers in Immunology
16. Ligand-gated ion channel P2X7 regulates hypoxia-induced factor-1α mediated pain induced by dental pulpitis in the medullary dorsal horn
    Jing Zhang, Jialin Si, Rongrong Liang, Yuxin Lu, Hongwei Shang, Xinwei Li, Shukai Sun, Lian Wu · 2022 · Frontiers in Molecular Neuroscience
17. Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages
    Line Lykke Andersen, Yiqi Huang, Christian Urban, Lila Oubraham, Elena Winheim, Che A. Stafford, Dennis Nagl, Fionan O’Duill, Thomas S. Ebert, Thomas Engleitner et al. · 2023 · The EMBO Journal
18. Role of the P2X7 receptor in breast cancer progression
    Yanan Du, Yahui Cao, Wei Song, Xin Wang, Qingqing Yu, Xiaoxiang Peng, Ronglan Zhao · 2024 · Purinergic Signalling
19. Arctiin Mitigates Neuronal Injury by Modulating the P2X7R/NLPR3 Inflammasome Signaling Pathway
    Guang‐Nan Jin, Yu Wang, Yiming Liu, Yu‐Nan Lu, Jing‐Mei Lu, Jing-He Wang, Ma Jingwen, Yan-Zhu Quan, Hongyan Gao, Yue‐Xian Cui et al. · 2024 · Inflammation
20. Characteristics and the role of purinergic receptors in pathophysiology with focus on immune response
    Marharyta Zyma, Rafał Pawliczak · 2020 · International Reviews of Immunology
21. Inflammatory Mediators Leading to Edema Formation through Plasma Membrane Receptors
    Guilherme Pegas Teixeira, Robson Xavier Faria · 2021 · IntechOpen eBooks
22. Translocator Protein Regulate Polarization Phenotype Transformation of Microglia after Cerebral Ischemia–reperfusion Injury
    Shadamu Yusuying, Shalayiding Yusuyin, Xiaojiang Cheng · 2021 · Neuroscience
23. Purinergic P2X7 Receptor: A Therapeutic Target in Amyotrophic Lateral Sclerosis
    André D. J. McKenzie, Taylor R. Garrett, Eryn L. Werry, Michael Kassiou · 2022 · ACS Chemical Neuroscience
24. Neurosteroids as positive and negative allosteric modulators of ligand-gated ion channels: P2X receptor perspective
    Sonja Sivcev, Eva Kudová, Hana W. Zemkova · 2023 · Neuropharmacology
25. The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation
    Iven-Alex von Mücke-Heim, Jana N. Martin, Manfred Uhr, Clemens Ries, Jan M. Deussing · 2023 · Frontiers in Pharmacology
26. P2X1 and P2X7 Receptor Overexpression Is a Negative Predictor of Survival in Muscle-Invasive Bladder Cancer
    Stephan Ledderose, Severin Rodler, Lennert Eismann, Georg Ledderose, Martina Rudelius, Wolfgang Georg JUNGER, Carola Ledderose · 2023 · Cancers
27. Risk Factors for Rotator Cuff Disease: An Experimental Study on Intact Human Subscapularis Tendons
    Fabian Plachel, Philipp Moroder, Renate Gehwolf, Herbert Tempfer, Andrea Wagner, Alexander Auffarth, Nicholas Matis, Stephan Pauly, Mark Tauber, Andreas Traweger · 2019 · Journal of Orthopaedic Research®
28. Maternal smoking during pregnancy aggravated muscle phenotype in FHL1 offspring mice similar to congenital clubfoot through P2RX7-mediated pyroptosis
    Yi Lou, Jianing Miao, Fang Li, Jingjing Ding, Lili Wang · 2021 · Toxicology Letters
29. A Methodological Approach Using rAAV Vectors Encoding Nanobody-Based Biologics to Evaluate ARTC2.2 and P2X7 In Vivo
    H. Gondé, Melanie Demeules, R. Hardet, A. Scarpitta, Marten Junge, Carolina Pinto-Espinoza, R. Varin, F. Koch-Nolte, O. Boyer, S. Adriouch · 2021 · Frontiers in Immunology
30. CD8 + , but not CD4 + effector/memory T cells, express the CD44 high CD45RB high phenotype with aging, which displays reduced expression levels of P2X 7 receptor and ATP‐induced cellular responses
    Amine Mellouk, Pierre Bobé · 2018 · The FASEB Journal
31. Cascade‐Targeted Nanoparticles for Enhanced Gemcitabine Delivery and Adenosine Metabolism Modulation to Overcome Treatment Resistance in Pancreatic Cancer
    Hongrui Fan, Hongyi Chen, Haolin Song, Chufeng Li, Yu Wang, Zhenhao Zhao, Qin Guo, Xuwen Li, Mingxuan Liu, Tao Sun et al. · 2025 · Advanced Science
32. Macrophage expression of P2X7 controls autoimmune uveitis
    Paul-Alexandre Déchelle-Marquet, Yueshen Che, Camille Roux, Frédéric Blond, Kaitryn E. Ronning, Sébastien Augustin, Pauline Lagouge-Roussey, Caroline Nous, Sara Touhami, Bahram Bodaghi et al. · 2025 · Journal of Neuroinflammation
33. The P2X7 purinergic receptor in intervertebral disc degeneration
    Letizia Penolazzi, Letícia Scussel Bergamin, Elisabetta Lambertini, Valentina Vultaggio-Poma, Alba Clara Sarti, Pasquale DE BONIS, Francesco Di Virgilio, Roberta Piva · 2021 · Journal of Cellular Physiology
34. Olfactory Ensheathing Cells Alleviate Facial Pain in Rats with Trigeminal Neuralgia by Inhibiting the Expression of P2X7 Receptor
    Jiafeng Lu, Baolin Yang, Jiayi Liao, Baokang Chen, Ming-Xin Lu, Wenjun Zhang, Jingnan Zeng, Hui Cheng, Zengxu Liu · 2022 · Brain Sciences
35. P2X7 Receptors in Astrocytes: A Switch for Ischemic Tolerance
    Yuri Hirayama, Naohiko Anzai, Hiroyuki Kinouchi, Schuichi Koizumi · 2022 · Molecules
36. Gentiopicroside alleviated epileptogenesis in immature rats through inactivation of NLRP3 inflammasome by inhibiting P2X7R expression
    Weilong Yang, Lin Ma, Siying Xu, Ping Zheng, Juan Du, Jing Hui Wu, Jian‐Qiang Yu, Tao Sun · 2022 · International Journal of Developmental Neuroscience
37. Inhibition of NLRP3 inflammasome activity by MCC950 leads to exacerbation of Sjӧgren's syndrome pathologies in non‐obese diabetic mice
    Jing Zhou, Shoko Onodera, Qing Yu · 2022 · Immunology
38. Purinergic Receptors P2X7 and P2X4 as Markers of Disease Progression in the rd10 Mouse Model of Inherited Retinal Dystrophy
    Natalia Martínez‐Gil, Oksana Kutsyr, Agustina Noailles, Laura Fernández‐Sánchez, Lorena Vidal, Xavier Sánchez‐Sáez, Carla Sánchez‐Castillo, Pedro Lax, Nicolás Cuenca, Antonio G. Garcı́a et al. · 2022 · International Journal of Molecular Sciences
39. P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis
    Érika Machado de Salles, Paulo Lisboa Raeder, Cláudia Blanes Angeli, Verônica Feijoli Santiago, Cristiane Naffah de Souza, Theresa Raquel de Oliveira Ramalho, Niels Olsen Saraiva Câmara, Giuseppe Palmisano, José María Álvarez, Maria Regina D’Império Lima · 2023 · Frontiers in Immunology
40. The P2X7 receptor in mucosal adaptive immunity
    F. Grassi, Rebecca B. Marino · 2023 · Purinergic Signalling Purinergic Signalling
41. Methotrexate Provokes Disparate Folate Metabolism Gene Expression and Alternative Splicing in Ex Vivo Monocytes and GM-CSF- and M-CSF-Polarized Macrophages
    Ittai B. Muller, Marry Lin, Róbert de Jonge, Nico Will, Baltasar López-Navarro, Conny J. van der Laken, Eduard A. Struys, Cees B.M. Oudejans, Yehuda G. Assaraf, Jacqueline J Cloos et al. · 2023 · International Journal of Molecular Sciences
42. Potential roles of enteric glial cells in Crohn's disease: A critical review
    Xinyi Mao, Jun Shen · 2023 · Cell Proliferation
43. CD39 (ENTPD1) in tumors: a potential therapeutic target and prognostic biomarker.
    Cuicui Li, Litian Zhang, Qiqi Jin, Haoyun Jiang, Chong-Yang Wu · 2023 · Biomarkers in Medicine
44. Caveolin-1 forms a complex with P2X7 receptor and tunes P2X7-mediated ATP signaling in mouse bone marrow-derived macrophages
    Yuuki Sawai, Yoshiaki Suzuki, Masataka Asagiri, Shigeaki Hida, Rubii Kondo, Gerald Werner Zamponi, Wayne R. Giles, Yuji Imaizumi, Hisao Yamamura · 2023 · American Journal of Physiology-Cell Physiology
45. Curcumin analogue NL04 inhibits spinal cord central sensitization in rats with bone cancer pain by inhibiting NLRP3 inflammasome activation and reducing IL-1β production
    Liping Chen, Bohan Hua, Qiuli He, Zixin Han, Yahui Wang, Yujing Chen, Huadong Ni, Zefeng Zhu, Longsheng Xu, Ming Yao et al. · 2024 · European Journal of Pharmacology
46. Tangzu granule alleviate neuroinflammation in diabetic peripheral neuropathy by suppressing pyroptosis through P2X7R /NLRP3 signaling pathway
    Haoyue Feng, Tingchao Wu, Jiawei Chin, Rui Ding, Caiyi Long, Gang Wang, Dawei Yan, Xi‐Tao Ma, Rensong Yue · 2024 · Journal of Ethnopharmacology
47. Selenoprotein P is a target for regulating extracellular vesicle biogenesis and secretion from activated microglia in vivo
    Victor Bodart‐Santos, Zhi Ruan, Bridgette C. Melvin, Ikshu Pandey, Seiko Ikezu, Tsuneya Ikezu · 2024 · Cell Reports
48. Gateway reflex: neural activation-mediated immune cell gateways in the central nervous system
    Kamimura, Daisuke, Ohki, Takuto, Arima, Yasunobu, Murakami, Masaaki · 2018 · International Immunology
49. The ART of tumor immune escape
    E. Wennerberg, S. Mukherjee, R. Sainz, B. Stiles · 2022 · Oncoimmunology
50. Characterization of Common Genetic Variants in P2RX7 and Their Contribution to Chronic Pain Conditions
    Katerina Zorina-Lichtenwalter, Ariel R. Ase, Vivek Verma, Arturo Israel Machuca‐Parra, Svetlana V. Komarova, Anmar Khadra, Philippe Séguéla, Luda B. Diatchenko · 2023 · Journal of Pain
51. The relationship between CD4+ follicular helper T cells and CD8+ resident memory T cells: sisters or distant cousins?
    Changwei Peng, Stephen C. Jameson · 2020 · International Immunology
52. PANX1 in inflammation heats up: New mechanistic insights with implications for injury and infection
    Juan C. Sanchez‐Arias, Leigh E. Wicki‐Stordeur, Rebecca C. Candlish, Emma van der Slagt, Irina Paci, Praveen P. N. Rao, Brian A. MacVicar, Leigh Anne Swayne · 2020 · Cell Calcium
53. Chemoresistance in Breast Cancer Patients Associated With Changes in P2X7 and A2A Purinergic Receptors in CD8+ T Lymphocytes
    Victor Manuel Ruiz-Rodríguez, Eneida Turiján-Espinoza, Jaime Arturo Guel-Pañola, Mariana Haydee García-Hernández, José de Jesús Zermeño-Nava, Nallely López‐López, Sofía Bernal‐Silva, Esther Layseca‐Espinosa, Ezequiel M. Fuentes‐Pananá, Ana María Estrada‐Sánchez et al. · 2020 · Frontiers in Pharmacology
54. Function of the P2X7 receptor in hematopoiesis and leukemogenesis
    Xiaoxiao He, Yaping Zhang, Yilu Xu, Li Xie, Zhuo Yu, Junke Zheng · 2021 · Experimental Hematology
55. Eukaryotic ADCY7 catalyzes the production of c-di-AMP to activate the NLRP3 inflammasome
    Qiannv Liu, Zhiheng Tang, Yan Qian, Chunlei Wang, Chun Kong, Mengqian Li, Xiangyang Geng, Yan Zhang, Xiangyun Cheng, Chao Ren et al. · 2025 · Nature Chemical Biology
56. Raspberry ketone alleviates radiation-induced lung injury through the STAT2-P2X7r/NLRP3 signaling pathway
    Yu-Chen Jiang, Bin Zhao, Peng Jiang, Siying Wang, Lin Ma, Wu Guoli, Manli Wang, Haiming Sun · 2025 · Phytomedicine
57. Resveratrol Alleviates Inflammatory Response Through P2X7/NLRP3 Signaling Pathway: In Silico and In Vitro Evidence from Activated Microglia
    Bianca Fagan Bissacotti, Marcylene Vieira da Silveira, Charles Elias Assmann, Priscila Marquezan Copetti, André Flores dos Santos, Solange Binotto Fagan, João Augusto Pereira da Rocha, Maria Rosa Chitolina Schetinger, Vera Maria Morsch, Nathieli Bianchin Bottari et al. · 2025 · Pharmaceuticals
58. P2 Purinergic Receptors in Tumor Immunity
    Xin Wang, Shu‐Heng Jiang, Mingyue Ma, Shuqi Cai, Dong Song, Bing Han · 2025 · Cancer Research
59. The P2X7 receptor/NLRP3 inflammasome signaling axis in sepsis: molecular mechanisms, organ-specific pathophysiology, and emerging therapeutic strategies
    Hilal Üstündağ · 2026 · Purinergic Signalling
60. Physiology of the volume-sensitive/regulatory anion channel VSOR/VRAC: part 2: its activation mechanisms and essential roles in organic signal release
    Yasunobu Okada · 2024 · The Journal of Physiological Sciences
61. Loss-of-function/gain-of-function polymorphisms of the ATP sensitive P2X7R influence sepsis, septic shock, pneumonia, and survival outcomes
    Johanna Guggemos, Stephen J. Fuller, Kristen K. Skarratt, Benjamin Mayer, E. Marion Schneider · 2024 · Frontiers in Immunology
62. The Purinergic P2X7 Receptor as a Target for Adjunctive Treatment for Drug-Refractory Epilepsy
    Divyeshz Thakku Sivakumar, Krishi Jain, Noura Alfehaid, Yitao Wang, Xinchen Teng, Wolfgang Fischer, Tobías Engel · 2024 · International Journal of Molecular Sciences
63. Mechanism of action of the nucleotide-binding oligomerization domain-like receptor protein 3 inflammasome and its regulation in liver injury
    Yifan Lu, Tianyu Wang, Bo Yu, Kang Xia, Jiayu Guo, Yiting Liu, Xiaoxiong Ma, Long Zhang, Jilin Zou, Zhongbao Chen et al. · 2024 · Chinese Medical Journal
64. EZH2-mediated suppression of TIMP1 in spinal GABAergic interneurons drives microglial activation via MMP-9-TLR2/4-NLRP3 signaling in neuropathic pain
    Li Wan, Haiyue Guo, Fan Hu, Yinbing Pan, Shuo Yang, Chun‐Yi Jiang, Wentao Liu, Xuefeng Wu, Xudong Wu · 2025 · Brain Behavior and Immunity
65. Biomaterials in Alzheimer's Disease: An Anti‐Neuroinflammatory Perspective
    Nanqu Huang, Wendi Huang, Mei Wang, Jingshan Shi, Yong Luo, Juan Huang · 2025 · Advanced Healthcare Materials
66. Adjunctive Thymosin Beta-4 Treatment Influences MΦ Effector Cell Function to Improve Disease Outcome in Pseudomonas aeruginosa-Induced Keratitis
    Yuxin Wang, Thomas W. Carion, Abdul Shukkur Ebrahim, Gabriel Sosne, Elizabeth A. Berger · 2021 · International Journal of Molecular Sciences
67. HYPERREFLECTIVE BAND IN THE GANGLION CELL LAYER IN RETINITIS PIGMENTOSA
    Alessio Antropoli, Alessandro Arrigo, Lorenzo Bianco, Elena Cavallari, Alessandro Berni, Filippo Casoni, G. Giacomo Consalez, Francesco Maria Bandello, Ottavio Cremona, Maurízio Battaglia Parodi · 2023 · Retina
68. Novel and differentially abundant microRNAs in sperm cells, seminal plasma, and serum of boars due to porcine reproduction and respiratory syndrome virus infection
    Samantha M. Calcatera, Darwin L. Reicks, Scott L. Pratt · 2018 · Animal Reproduction Science
69. The ATP/P2X7 axis in human immunodeficiency virus infection of macrophages
    Francesca Graziano, Elisa Vicenzi, Guido Poli · 2019 · Current Opinion in Pharmacology
70. Murine iNKT cells are depleted by liver damage via activation of P2RX7
    Astrid A. Bovens, Thomas H. Wesselink, Felix M. Behr, N. Kragten, René A. W. Lier, Klaas P. J. M. Gisbergen, Regina Stark · 2020 · European Journal of Immunology
71. Trichomonas vaginalis NTPDase inhibited by lycorine modulates the parasite-neutrophil interaction
    Brenda Petró-Silveira, Graziela Vargas Rigo, Danielle da Silva Trentin, Alexandre José Macêdo, Elisa Saüer, Elen de Oliveira Alves, Luciana R. Tallini, Solange Cristina García, Warley de Souza Borges, José Ângelo Silveira Zuanazzi et al. · 2020 · Parasitology Research
72. Making Sense of Intracellular Nucleic Acid Sensing in Type I Interferon Activation in Sjögren’s Syndrome
    Erika Huijser, Marjan A. Versnel · 2021 · Journal of Clinical Medicine
73. Correlations between Serum P2X7, Vitamin A, 25‐hydroxy Vitamin D, and Mycoplasma Pneumoniae Pneumonia
    Fanjun Meng, Ping Chen, Xiaolong Guo, Xiaoru Li, Yuexuan Wu, Wenen Liu, Feng Jiang, Huan Liu, Lixin Wang · 2021 · Journal of Clinical Laboratory Analysis
74. Editorial: P2X7 as Common Therapeutic Target in Brain Diseases
    Tobías Engel, Annette Nicke, Jan M. Deussing, Beáta Sperlágh, Miguel Dı́az-Hernández · 2021 · Frontiers in Molecular Neuroscience
75. Potential skin health promoting benefits of costunolide: a therapeutic strategy to improve skin inflammation in imiquimod-induced psoriasis
    Zi‐Ying Zhan, Zhihong Zhang, Hongxu Yang, Yan‐Ling Wu, Ji‐Xing Nan, Li‐Hua Lian · 2023 · Food & Function
76. Purinergic signaling via P2X receptors and mechanisms of unregulated ATP release in the outer retina and age-related macular degeneration
    Haydn Molcak, Kailun Jiang, Christopher J. Campbell, Joanne Aiko Matsubara · 2023 · Frontiers in Neuroscience
77. Extracellular ATP (eATP) inhibits the progression of endometriosis and enhances the immune function of macrophages
    Ling Zhou, E. Cai, Huiping Liu, Hongyan Cheng, Xue Ye, Honglan Zhu, Xiaohong Chang · 2023 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
78. Assessment of toxicological effects of favipiravir (T‐705) on the lung tissue of rats: An experimental study
    Elif Erbaş, Nevra Aydemi̇r Celep, Deniz Tekiner, Aydın Genç, Semin Gedikli · 2023 · Journal of Biochemical and Molecular Toxicology
79. Transplantation of olfactory ensheathing cells can alleviate neuroinflammatory responses in rats with trigeminal neuralgia
    Jiafeng Lu, Baolin Yang, Wenjun Zhang, Hui Cheng, Jingnan Zeng, Yuan-li Wang, Wei Wei, Zengxu Liu · 2023 · Brain Research
80. P2X7 receptor inhibition alleviates mania-like behavior independently of interleukin-1β
    Flóra Gölöncsér, Mária Baranyi, Pál Tod, Fruzsina Maácz, Beáta Sperlágh · 2024 · iScience
81. Mitochondrial damage and clearance in retinal pigment epithelial cells
    Iswariyaraja Sridevi Gurubaran · 2024 · Acta Ophthalmologica
82. Increased Cerebral Level of P2X7R in a Tauopathy Mouse Model by PET Using [18F]GSK1482160
    Yanyan Kong, Lei Cao, Jiao Wang, Junyi Zhuang, Yongshan Liu, Lei Bi, Yifan Qiu, Yuyi Hou, Qi Huang, Fang Xie et al. · 2024 · ACS Chemical Neuroscience
83. Assessment of NLRP3 inflammasome activation in patients with chronic obstructive pulmonary disease before and after lung transplantation
    Lada Rumora, Ivona Markelić, Iva Hlapčić, Andrea Hulina Tomašković, Marija Fabijanec, Feđa Džubur, Miroslav Samaržija, Andrea Vukić Dugac · 2024 · Immunologic Research
84. Dexmedetomidine Alleviates Acute Stress-Induced Acute Kidney Injury by Attenuating Inflammation and Oxidative Stress via Inhibiting the P2X7R/NF-κB/NLRP3 Pathway in Rats
    Haotian Yang, Yuan Zhao, Yongping Chen, Tianyuan Yang, Xinyi Dou, Junfeng Li, Guiyan Yang, Guofeng Feng, Hao Fang, Honggang Fan et al. · 2024 · Inflammation
85. ML335 inhibits TWIK2 channel-mediated potassium efflux and attenuates mitochondrial damage in MSU crystal-induced inflammation
    Dianze Song, Xiaoqin Zhou, Qingqing Yu, Renjie Li, Qian Dai, Mei Zeng · 2024 · Journal of Translational Medicine
86. Receptors on Microglia
    Marcus Augusto‐Oliveira, Marie‐Ève Tremblay, Alexei Verkhratsky · 2024 · Advances in neurobiology
87. Both host and parasite non-coding RNAs co-ordinate the regulation of macrophage gene expression to reduce pro-inflammatory immune responses and promote tissue repair pathways during infection with fasciola hepatica
    Dayna Sais, Sumaiya Chowdhury, John P. Dalton, Nham Tran, Sheila Donnelly · 2024 · RNA Biology
88. Cytosolic delivery of innate immune agonists
    Ravi Bharadwaj, Swati Jaiswal, Neal S. Silverman · 2024 · Trends in Immunology
89. Jatrorrhizine alleviates cytokine storm secondary lung injury via regulating CD39 ‐dominant purinergic braking and downstream NLRP3 inflammasome
    Yuejia Lan, Huan Wang, Lijia Jing, Rui Li, Jiayi Sun, Xianli Meng, Jiasi Wu · 2025 · Phytotherapy Research
90. Cholinergic and purinergic systems: A key to multiple sclerosis?
    Carla Roberta Nunes Polachini, Rosélia Maria Spanevello, Maria Rosa Chitolina Schetinger, Vera Maria Morsch · 2018 · Journal of the Neurological Sciences
91. P2X7 Receptor Expression and Signaling on Dendritic Cells and CD4+ T Cells is Not Required but Can Enhance Th17 Differentiation
    Yin Yang, Meaghan E Story, Xingxing Hao, Tina L. Sumpter, Alicia R. Mathers · 2022 · Frontiers in Cell and Developmental Biology
92. Extracellular ATP and Imbalance of CD4+ T Cell Compartment in Pediatric COVID-19
    Constanza Russo, Silvina Raiden, Silvia Algieri, Norberto De Carli, Carolina Davenport, Mariam Sarli, María José Bruera, Vanesa Seery, Inés Sananez, Nancy Simaz et al. · 2022 · Frontiers in Cellular and Infection Microbiology
93. Pathways Related to NLRP3 Inflammasome Activation Induced by Gold Nanorods
    Rob J. Vandebriel, Sylvie Rémy, Jolanda P. Vermeulen, Evelien G. E. Hurkmans, Kirsten J. Kevenaar, Neus G. Bastús, Beatriz Pelaz, Mahmoud G. Soliman, Víctor Puntes, Wolfgang Johann Parak et al. · 2022 · International Journal of Molecular Sciences
94. Ocular P2 receptors and glaucoma
    Youichi Shinozaki, Kozo Saito, Kenji Kashiwagi, Schuichi Koizumi · 2022 · Neuropharmacology
95. Origin, distribution, and function of three frequent coding polymorphisms in the gene for the human P2X7 ion channel
    Waldemar Schäfer, Tobias Stähler, Carolina Pinto-Espinoza, Welbeck Danquah, Jan Knop, Björn Rissiek, Friedrich Haag, Friedrich Koch‐Nolte · 2022 · Frontiers in Pharmacology
96. Bullatine A has an antidepressant effect in chronic social defeat stress mice; Implication of microglial inflammasome
    Jiarui Zhang, Shu-Yuan Yin, Zu-Qi Shen, Bing Li, Yu‐Qiu Zhang, Jin Ming Yu · 2023 · Brain Research Bulletin
97. Canonical Inflammasomes
    Vinícius Nunes Cordeiro Leal, Alessandra Pontillo · 2023 · Methods in molecular biology
98. Multi-walled carbon nanotubes induce IL-1β secretion by activating hemichannels-mediated ATP release in THP-1 macrophages
    Jingpu Fan, Yiyong Chen, Di Yang, Jie Shen, Xinbiao Guo · 2020 · Nanotoxicology
99. Does Cholinergic Stimulation Affect the P2X7 Receptor-Mediated Dye Uptake in Mast Cells and Macrophages?
    Dilyara Nurkhametova, Andrei E. Siniavin, Maria A. Streltsova, Denis S. Kudryavtsev, Igor Vladimirovich Kudryavtsev, Raisa Giniatullina, Victor I. Tsetlin, Tarja Malm, Rashid A. Giniatullin · 2020 · Frontiers in Cellular Neuroscience
100. Metformin alleviates hydrogen peroxide–induced inflammation and oxidative stress via inhibiting P2X7R signaling in spinal cord tissue cells neurons
     Gang Wang, Shurui Chen, Zhenya Shao, Yankun Li, Wei Wang, Liang Mao, Jian Li, Xifan Mei · 2020 · Canadian Journal of Physiology and Pharmacology