Germinal Center and Extrafollicular B Cell Responses in Vaccination, Immunity, and Autoimmunity

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Items 201–300 of 526

  1. Different Patterns of Autoantibody Secretion by Peripheral Blood Mononuclear Cells in Autoimmune Nodopathies
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  3. Defective germinal center selection results in persistence of self-reactive B cells from the primary to the secondary repertoire in Primary Antiphospholipid Syndrome
    Yannick Dieudonné, Raquel Lorenzetti, Julien Rottura, Iga Janowska, Quentin Frenger, Léa Jacquel, Olivier Vollmer, Francesco Carbone, Chengsong Zhu, Marine Luka et al. · 2024 · Nature Communications
  4. From immunobiology to intervention: Pathophysiology of autoimmune encephalitis
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  6. An intranasal adjuvanted, recombinant influenza A/H5 vaccine primes against diverse H5N1 clades: a phase I trial
    Meagan E. Deming, Franklin R. Toapanta, Marcela F. Pasetti, Hana Golding, Surender Khurana, Tarek Hamouda, Ali Fattom, Yuanyuan Liang, Sharon M. Tennant, Megan F. McGilvray et al. · 2025 · Nature Communications
  7. Hybrid and SARS-CoV-2-vaccine immunity in kidney transplant recipients
    Hassen Kared, Amin Alirezaylavasani, Katrine Persgård Lund, Adity Chopra, Lisa Tietze, Taissa de Matos Kasahara, Guro Løvik Goll, Gunnveig Grødeland, Mari Kaarbø, Anna Varberg Reisæter et al. · 2023 · EBioMedicine
  8. microRNA Fine-Tuning of the Germinal Center Response
    Teresa Fuertes, Irene Rivera Salgado, Virginia G. de Yébenes · 2021 · Frontiers in Immunology
  9. Malignant hyperthermia susceptibility: cardiac histomorphometry of dogs and young and market-weight swine.
    Peter James O'Brien, Thomas F. Fletcher, A L Metz, Harold J. Kurtz, Brian K. Reed, William E. Rempel, E G Clark, Charles F. Louis · 1987 · PubMed Central
  10. B cell development and antibody responses in human immune system mice: current status and future perspective
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  11. Mechanisms of antibody mediated immunity – Distinct in early life
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  12. Cellular pathways and molecular events that shape autoantibody production in COVID-19
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  13. Immunosuppression Management in Heart Transplantation
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  14. Targeting B Cells and Plasma Cells in Glomerular Disease
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  15. Pregnancy reduces COVID-19 vaccine immunity against novel variants
    Maclaine A. Parish, Jaiprasath Sachithanandham, Lizeth Gutierrez, Han-Sol Park, Anna Yin, Katerina Roznik, Patrick S. Creisher, John S. Lee, Laura A. St Clair, Annie Werner et al. · 2025 · npj Vaccines
  16. Immune Niches in Cancer
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  17. Adaptive Immunity to Viruses: What Did We Learn from SARS-CoV-2 Infection?
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  18. EBV dUTPase: A Novel Modulator of Inflammation and the Tumor Microenvironment in EBV-Associated Malignancies
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  19. Overview of human B-cell development and antibody deficiencies.
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  20. ImmuneLENS characterizes systemic immune dysregulation in aging and cancer
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  21. New Onset Generalized Myasthenia Gravis Evolving Following SARS-CoV-2 Infection
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  22. Neutralizing Antibodies Against Factor VIII Can Occur Through a Non-Germinal Center Pathway
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  23. The cellular biology of plasma cells: Unmet challenges and opportunities
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  24. Memory B cell fitness and anergy has significant links to cancer lethality
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  25. A 3-week pause versus continued Bruton tyrosine kinase inhibitor use during COVID-19 vaccination in individuals with chronic lymphocytic leukaemia (IMPROVE trial): a randomised, open-label, superiority trial
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  26. Transplants foster B cell alloimmunity by relaying extracellular vesicles to follicular dendritic cells
    Rao Chen, Juliana S. Powell, William J. Shufesky, Elissa Bardhi, Mara L. G. Sullivan, Olga A. Tkacheva, Geoffrey Camirand, Zoe Goncalves, Donna Beer Stolz, Geetha Chalasani et al. · 2025 · Cell Reports
  27. Engineering B cells to treat and study human disease
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  28. Examining B-cell dynamics and responsiveness in different inflammatory milieus using an agent-based model
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  29. There and back again? A B cell’s tale on responses and spatial distribution in teleosts
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  30. Developmental immunology and role of host defenses in fetal and neonatal susceptibility to infection
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  31. Study of immunogenicity and efficacy against Omicron BA.5 of recombinant protein-based COVID-19 vaccine delivered by intramuscular and mucosal routes in nonhuman primates
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  32. Human LUBAC deficiency leads to autoinflammation and immunodeficiency by dysregulation in TNF-mediated cell death
    Hirotsugu Oda, Kalpana Manthiram, Pallavi Pimpale Chavan, Shuichiro Nakabo, Hye Sun Kuehn, David B. Beck, Jae Jin Chae, Michele E. Nehrebecky, Amanda K. Ombrello, Tina Romeo et al. · 2022 · medRxiv
  33. Aging and immunity: the age-old tango
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  34. Lympho-myeloid aggregate-infiltrating CD20+ B cells display a double-negative phenotype and correlate with poor prognosis in esophageal squamous cell carcinoma
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  35. Congenital T-cell activation impairs transitional-to-follicular B-cell maturation in humans
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  36. Compromised B-cell homeostasis: Unraveling the link between major depression, infection and autoimmune disorders
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  37. Innate Immune Receptors as Dynamic Modulators of Extrafollicular Autoimmune B Cell Response
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  38. Astragalus polysaccharide and aluminum adjuvant synergize to amplify immune responses induced by a recombinant COVID-19 vaccine
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  39. Effect of same-arm versus cross-arm administration of sequential doses of BNT162b2 on short-term vaccine effectiveness—a retrospective cohort study
    Daniel Grupel, Yehonatan Pasternak, Yochai Schonmann · 2022 · Clinical Microbiology and Infection
  40. B cells! Don’t go the wrong way in this tumor
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  41. Thymic B Cells as a New Player in the Type 1 Diabetes Response
    Richard B. Greaves, Dawei Chen, E. Allison Green · 2021 · Frontiers in Immunology
  42. Age-related changes of the human splenic marginal zone B cell compartment
    Artur Kibler, Marc Seifert, Bettina Budeus · 2023 · Immunology Letters
  43. B cells and atherosclerosis: A HIV perspective
    Laventa M. Obare, Rachel H. Bonami, Amanda C. Doran, Celestine N. Wanjalla · 2024 · Journal of Cellular Physiology
  44. Single-cell transcriptome analysis of the early immune response in the lymph nodes of Borrelia burgdorferi-infected mice
    Varpu Rinne, Kirsi Gröndahl‐Yli‐Hannuksela, Ruth Fair-Mäkelä, Marko Salmi, Pia Rantakari, Tapio Lönnberg, Jukka Alinikula, Annukka Pietikäinen, Jukka Hytönen · 2024 · Microbes and Infection
  45. The balance between conventional and unconventional T follicular helper cells influences autoreactive B cell responses
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  46. T follicular helper cells in primary immune regulatory disorders
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  47. B cell depletion as a therapeutic strategy for neuromyelitis optica spectrum disorder: rationale, evidence, and challenges
    Hirofumi Ochi, Satoru Nakamura, Jin Nakahara · 2025 · Frontiers in Immunology
  48. Quantifying the waning of humoral immunity
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  49. The BAFF/APRIL system at the crossroads of B cell memory and autoimmune relapse: Implication into the therapeutic strategies
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  50. Germline-encoded specificities and the predictability of the B cell response
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  51. Plasmablastic Lymphoma
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  52. Transcriptomic Analysis Reveals Sixteen Potential Genes Associated with the Successful Differentiation of Antibody-Secreting Cells through the Utilization of Unfolded Protein Response Mechanisms in Robust Responders to the Influenza Vaccine
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  53. From bench to bedside: reversing established antibody responses and desensitization
    Anita S. Chong, Marlena V. Habal · 2022 · Current Opinion in Organ Transplantation
  54. Selenium saves ferroptotic TFH cells to fortify the germinal center
    Michelle A. Linterman, Alice E. Denton · 2021 · Nature Immunology
  55. Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1)
    Lucy Gordon, Neil Andrew Mabbott, Joanna Wells, Liudmila N. Kulik, Nick Juleff, Bryan Charleston, Eva Pérez-Martín · 2022 · PLoS Pathogens
  56. IgTreeZ, A Toolkit for Immunoglobulin Gene Lineage Tree-Based Analysis, Reveals CDR3s Are Crucial for Selection Analysis
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  57. Germinal Center Response to mRNA Vaccination and Impact of Immunological Imprinting on Subsequent Vaccination
    Wooseob Kim · 2024 · Immune Network
  58. B Cell Receptor Repertoire Analysis of the CD21 lo B Cell Compartment in Healthy Individuals, Patients With Sjögren's Disease, and Patients With Radiographic Axial Spondyloarthritis
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  59. Pathogenic IgE-fated memory B cell responses retain functional plasticity
    Kelly M. Bruton, Allyssa Phelps, Atai Ariaz, Allison Fang, Tina D. Walker, Jianping Wen, Sharon S. Khavkine-Binstock, Danielle Della Libera, Olivia Mann-Delany, Niels Peter Hell Knudsen et al. · 2026 · Science Immunology
  60. B-Cells and Plasmablasts as Architects of Autoimmune Disease: From Molecular Footprints to Precision Therapeutics
    Julie Sarrand, Muhammad Shahnawaz Soyfoo · 2026 · Cells
  61. In vivo CRISPR/Cas9 screens identify new regulators of B cell activation and plasma cell differentiation
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  62. Excess BAFF May Impact HIV-1-Specific Antibodies and May Promote Polyclonal Responses Including Those from First-Line Marginal Zone B-Cell Populations
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  63. The Impact of HIV on B Cell Compartment and Its Implications for COVID-19 Vaccinations in People with HIV
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  64. Citrulline enteral administration markedly reduces immunosuppressive extrafollicular plasma cell differentiation in a preclinical model of sepsis
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  65. Complex subsets but redundant clonality after B cells egress from spontaneous germinal centers
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  66. Single‐cell RNA sequencing reveals the landscape of biomarker in allergic rhinitis patient undergoing intracervical lymphatic immunotherapy and related pan‐cancer analysis
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  68. Increased autoreactivity and maturity of EBI2+ antibody-secreting cells from nasal polyps
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  69. Structural mapping of polyclonal IgG responses to HA after influenza virus vaccination or infection
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  70. The comprehensive insights into the B-cells-mediated immune response against COVID-19 infection amid the ongoing evolution of SARS-CoV-2
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  71. Antigen mobility regulates the dynamics and precision of antigen capture in the B cell immune synapse
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  72. Comparable antigen-specific T cell responses in vaccinees with diverse humoral immune responses after the primary and booster BBIBP-CorV vaccination
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  73. Evaluation of BAFF, APRIL and CD40L in Ocrelizumab-Treated pwMS and Infectious Risk
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  74. Virus-specific antibody secreting cells reside in the peritoneal cavity and systemic immune sites of Atlantic salmon (Salmo salar) challenged intraperitoneally with salmonid alphavirus
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  75. PD-1 high CXCR5 – CD4 + Peripheral Helper T (Tph) cells Promote Tissue-Homing Plasmablasts in COVID-19
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  76. Accelerated waning of the humoral response to SARS-CoV-2 vaccines in obesity
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  77. Deep profiling of antigen-specific B cells from different pathogens identifies novel compartments in the IgG memory B cell and antibody-secreting cell lineages
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  78. TNF inhibitors affect the induction and maintenance of spike-specific B-cell responses after mRNA vaccination
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  79. CFP1 promotes germinal center affinity maturation and restrains memory B cell differentiation through H3K4me3 modulation
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  80. Lymphocyte-derived cholinergic circuits modulate germinal center output and B cell activation
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  81. B lymphocytes that enter the germinal center late preferentially differentiate into memory cells that recognize subdominant epitopes
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  82. Serial intravital microscopy reveals temporal dynamics of autoreactive germinal centers in the spleen
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  83. B Cells at the Core: Immune Mechanisms and Therapeutic Potentials in Periapical Lesions
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  84. Hypoxia-adenosinergic regulation of B cell responses
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  85. Arctigenin inhibits abnormal germinal center reactions and attenuates murine lupus by inhibiting IFN-I pathway
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  86. Improving naive B cell isolation by absence of CD45RB glycosylation and CD27 expression in combination with BCR isotype
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  87. Crosstalk in the diseased plasma cell niche – the force of inflammation
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  88. Clonal relationships of memory B cell subsets in autoimmune mice
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  89. Pre-existing CD4 T cell help boosts antibody responses but has limited impact on germinal center, antigen-specific B cell frequencies after influenza infection
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  90. Increased development of T-bet+CD11c+ B cells predisposes to lupus in females: Analysis in BXD2 mouse and genetic crosses
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  91. Characterizing adjuvants’ effects at murine immunoglobulin repertoire level
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  92. Anti-spike antibody responses to SARS-CoV-2 mRNA vaccines in people with schizophrenia and schizoaffective disorder
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  93. Antibody-mediated immunological memory correlates with long-term Lyme veterinary vaccine protection in mice
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  94. Deep sequencing of BCR heavy chain repertoires in myalgic encephalomyelitis/chronic fatigue syndrome
    Audrey A. Ryback, Graeme J. M. Cowan · 2025 · Frontiers in Immunology
  95. Microbiome-mediated modulation of immune memory to P. yoelii affects the resistance to secondary cerebral malaria challenge
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  96. Pathogenic Roles of Age‐Associated B Cells in Neuromyelitis Optica Spectrum Disorder
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  97. Poor immunogenicity upon SARS-CoV-2 mRNA vaccinations in autoimmune SLE patients is associated with pronounced EF-mediated responses and anti-BAFF/Belimumab treatment
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  98. B cell expression of an enzymatic intermediary in ether lipid biosynthesis promotes antibody responses and germinal center size
    Sung Hoon Cho, Marissa A. Jones, Kaylor Meyer, David M. Anderson, Sergei V. Chetyrkin, M. Wade Calcutt, Richard M. Caprioli, Clay F. Semenkovich, Mark Robin Boothby · 2025 · eLife
  99. Mucosal B cell memory selection integrates tissue-specific cues via the IgA BCR
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  100. Extrafollicular B cell responses are associated with autoreactivity against the slit diaphragm in idiopathic podocytopathies
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