Melatonin Prevents Endothelial Dysfunction in SLE by Activating the Nuclear Receptor Retinoic Acid-Related Orphan Receptor-α

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

Hochberg, M. C. (1997) · Arthritis & Rheumatism · doi:10.1002/art.1780400928 · Cited by 11,409 · see citing works

Endothelial Cell Dysfunction and the Pathobiology of Atherosclerosis

Gimbrone, M. A., & García‐Cardeña, G. (2016) · Circulation Research · doi:10.1161/circresaha.115.306301 · Cited by 3,554 · see citing works

Roles of vascular oxidative stress and nitric oxide in the pathogenesis of atherosclerosis

Förstermann, U., Xia, N., & Li, H. (2017) · Circulation Research · doi:10.1161/circresaha.116.309326 · Cited by 1,519 · see citing works

Systemic lupus erythematosus

Lisnevskaia, L., Murphy, G., & Isenberg, D. (2014) · The Lancet · doi:10.1016/s0140-6736(14)60128-8 · Cited by 752 · see citing works

Retinoid-Related Orphan Receptors (RORs): Critical Roles in Development, Immunity, Circadian Rhythm, and Cellular Metabolism

Jetten, A. M. (2009) · Nuclear Receptor Signaling · doi:10.1621/nrs.07003 · Cited by 675 · see citing works

Vascular oxidative stress, nitric oxide and atherosclerosis

Li, H., Horke, S., & Förstermann, U. (2014) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2014.09.001 · Cited by 656 · see citing works

Oxidative stress and vascular inflammation in aging

Assar, M. E., Angulo, J., & Rodríguez‐Mañas, L. (2013) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2013.07.003 · Cited by 576 · see citing works

Vascular endothelium, hemodynamics, and the pathobiology of atherosclerosis

Gimbrone, M. A., & García‐Cardeña, G. (2012) · Cardiovascular Pathology · doi:10.1016/j.carpath.2012.06.006 · Cited by 432 · see citing works

Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration

Huynh, J., Nishimura, N., Rana, K., Peloquin, J. M., Califano, J. P., Montague, C. R., King, M. R., Schaffer, C. B., & Reinhart‐King, C. A. (2011) · Science Translational Medicine · doi:10.1126/scitranslmed.3002761 · Cited by 403 · see citing works

Accelerated atherosclerosis in patients with SLE—mechanisms and management

Skaggs, B. J., Hahn, B. H., & McMahon, M. A. (2012) · Nature Reviews Rheumatology · doi:10.1038/nrrheum.2012.14 · Cited by 253 · see citing works

Mechanisms Involved in the Aging-Induced Vascular Dysfunction

Fuente, M. E. A. D. L., Angulo, J., Fernán, S. E., Peiró, C., Sánchez‐Ferrer, C. F., & Rodríguez‐Mañas, L. (2012) · Frontiers in Physiology · doi:10.3389/fphys.2012.00132 · Cited by 226 · see citing works

Molecular mechanism of endothelial and vascular aging: implications for cardiovascular disease

Camici, G. G., Savarese, G., Akhmedov, A., & Lüscher, T. F. (2015) · European Heart Journal · doi:10.1093/eurheartj/ehv587 · Cited by 223 · see citing works

Cardiovascular disease in systemic lupus erythematosus: A comprehensive update

Giannelou, M., & Mavragani, C. P. (2017) · Journal of Autoimmunity · doi:10.1016/j.jaut.2017.05.008 · Cited by 172 · see citing works

Short‐term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress

Rippe, C., Lesniewski, L. A., Connell, M. L., LaRocca, T. J., Donato, A. J., & Seals, D. R. (2010) · Aging Cell · doi:10.1111/j.1474-9726.2010.00557.x · Cited by 158 · see citing works

Advanced age results in a diminished endothelial glycocalyx

Machin, D. R., Bloom, S. I., Campbell, R. A., Phuong, T. T. T., Gates, P. E., Lesniewski, L. A., Rondina, M. T., & Donato, A. J. (2018) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00104.2018 · Cited by 121 · see citing works

Melatonin ameliorates vascular endothelial dysfunction, inflammation, and atherosclerosis by suppressing the TLR 4/ NF ‐κB system in high‐fat‐fed rabbits

Hu, Z.-P., Fang, X., Nan, F., Wang, X., Qian, H., Cao, Z., Cheng, Y., Wang, B., & Wang, Y. (2013) · Journal of Pineal Research · doi:10.1111/jpi.12085 · Cited by 114 · see citing works

Melatonin stabilizes rupture‐prone vulnerable plaques via regulating macrophage polarization in a nuclear circadian receptor RORα‐dependent manner

Ding, S. Z., Lin, N., Sheng, X., Zhao, Y., Su, Y., Xu, L., Tong, R., Yang, Y., Fu, Y., He, J., et al. (2019) · Journal of Pineal Research · doi:10.1111/jpi.12581 · Cited by 113 · see citing works

Melatonin inhibits LPS‐induced NO production in rat endothelial cells

Tamura, E. K., Cecon, E., Monteiro, A. W. A., Silva, C. L. M., & Markus, R. P. (2009) · Journal of Pineal Research · doi:10.1111/j.1600-079x.2008.00657.x · Cited by 104 · see citing works

Single photon emission computed tomography dual isotope myocardial perfusion imaging in women with systemic lupus erythematosus. I. Prevalence and distribution of abnormalities.

Bruce, I. N., Burns, R. J., Gladman, D., & Mb, U. (2000) · PubMed · Cited by 98 · see citing works

Roles of Cells from the Arterial Vessel Wall in Atherosclerosis

Wang, D., Wang, Z., Zhang, L., & Wang, Y. (2017) · Mediators of Inflammation · doi:10.1155/2017/8135934 · Cited by 97 · see citing works

Melatonin and its atheroprotective effects: A review

Favero, G., Rodella, L. F., Reiter, R. J., & Rezzani, R. (2013) · Molecular and Cellular Endocrinology · doi:10.1016/j.mce.2013.11.016 · Cited by 79 · see citing works

Daily melatonin protects the endothelial lineage and functional integrity against the aging process, oxidative stress, and toxic environment and restores blood flow in critical limb ischemia area in mice

Lee, F., Sun, C., Sung, P., Chen, K., Chua, S. O., Sheu, J., Chung, S., Chai, H., Chen, Y., Huang, T., et al. (2018) · Journal of Pineal Research · doi:10.1111/jpi.12489 · Cited by 72 · see citing works

Endothelial Alterations in Systemic Lupus Erythematosus and Rheumatoid Arthritis: Potential Effect of Monocyte Interaction

Atehortúa, L., Rojas, M., Vásquez, G. M., & Castaño, D. (2017) · Mediators of Inflammation · doi:10.1155/2017/9680729 · Cited by 71 · see citing works

Melatonin differentially regulates pathological and physiological cardiac hypertrophy: Crucial role of circadian nuclear receptor RORα signaling

Xu, L., Su, Y., Zhao, Y., Sheng, X., Tong, R., Ying, X., Gao, L., Ji, Q., Gao, Y., Yang, Y., et al. (2019) · Journal of Pineal Research · doi:10.1111/jpi.12579 · Cited by 69 · see citing works

Nox2 regulates endothelial cell cycle arrest and apoptosis via p21cip1 and p53

Li, J., Fan, L. M., George, V. T., & Brooks, G. (2007) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2007.06.001 · Cited by 65 · see citing works

Systemic lupus erythematosus and atherosclerosis: Review of the literature

Frieri, M., & Stampfl, H. (2015) · Autoimmunity Reviews · doi:10.1016/j.autrev.2015.08.007 · Cited by 63 · see citing works

Update on cardiovascular disease in lupus

Lewandowski, L. B., & Kaplan, M. J. (2016) · Current Opinion in Rheumatology · doi:10.1097/bor.0000000000000307 · Cited by 62 · see citing works

Fibroblast growth factor 21 delayed endothelial replicative senescence and protected cells from H2O2-induced premature senescence through SIRT1.

Yan, J., Wang, J., Huang, H., Huang, Y., Mi, T., Zhang, C., & Zhang, L. (2017) · PubMed Central · Cited by 48 · see citing works

The NADPH oxidases NOX4 and DUOX2 regulate cell cycle entry via a p53-dependent pathway

Salmeen, A. E., Park, B. O., & Meyer, T. (2010) · Oncogene · doi:10.1038/onc.2010.200 · Cited by 47 · see citing works

Interleukin-4 and melatonin ameliorate high glucose and interleukin-1β stimulated inflammatory reaction in human retinal endothelial cells and retinal pigment epithelial cells.

Xie, M., Hu, A., Luo, Y., Sun, W., Hu, X., & Tang, S. (2014) · PubMed Central · Cited by 40 · see citing works

Sex-Dependent Effect of Melatonin on Systemic Erythematosus Lupus Developed in Mrl/Mpj-Faslpr Mice: It Ameliorates the Disease Course in Females, whereas It Exacerbates It in Males

Jiménez‐Caliani, A. J., Jiménez‐Jorge, S., Molinero, P., Fernández-Santos, J. M., Martín‐Lacave, I., Rubio, A., Guerrero, J. M., & Osuna, C. (2005) · Endocrinology · doi:10.1210/en.2005-0648 · Cited by 36 · see citing works

Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress

Morgan, R. G., Walker, A. E., Trott, D. W., Machin, D. R., Henson, G. D., Reihl, K. D., Cawthon, R., Denchi, E. L., Liu, Y., Bloom, S. I., et al. (2018) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2018.11.014 · Cited by 36 · see citing works

Melatonin ameliorates blood–brain barrier permeability, glutathione, and nitric oxide levels in the choroid plexus of the infantile rats with kaolin-induced hydrocephalus

Turgut, M., Erdoğan, S., Ergin, K., & Serter, M. (2007) · Brain Research · doi:10.1016/j.brainres.2007.07.056 · Cited by 35 · see citing works

RORα1 and RORα4 suppress TNF‐α‐induced VCAM‐1 and ICAM‐1 expression in human endothelial cells

Migita, H., Satozawa, N., Lin, J.-H., Morser, J., & Kawai, K. (2003) · FEBS Letters · doi:10.1016/s0014-5793(03)01502-3 · Cited by 34 · see citing works

Decreased Daily Melatonin Levels in Women with Systemic Lupus Erythematosus - A Short Report

Robeva, R. N., Tanev, D., Кirilov, G., Stoycheva, M., Tomova, A., Kumanov, P., Rashkov, R. K., & Kolarov, Z. (2013) · Balkan Medical Journal · doi:10.5152/balkanmedj.2013.8064 · Cited by 28 · see citing works

Melatonin Improves Parthenogenetic Development of Vitrified–Warmed Mouse Oocytes Potentially by Promoting G1/S Cell Cycle Progression

Pan, B., Yang, H., Wu, Z., Qazi, I. H., Liu, G., Han, H., Meng, Q., & Zhou, G. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19124029 · Cited by 27 · see citing works

Effects of melatonin on mechanisms involved in hypertension using human umbilical vein endothelial cells

Shao, G., Zhang, S., Nie, J., Li, J., & Tong, J. (2017) · Journal of Toxicology and Environmental Health · doi:10.1080/15287394.2017.1384171 · Cited by 20 · see citing works

The small molecule macrophage migration inhibitory factor antagonist MIF098, inhibits pulmonary hypertension associated with murine SLE

Huang, H., Chen, D., Pu, J., Yuan, A., Fu, Q., Li, J., Leng, L., Bucala, R., Ye, S., & Lu, L. (2019) · International Immunopharmacology · doi:10.1016/j.intimp.2019.105874 · Cited by 14 · see citing works

Mechanisms of NAT10 as ac4C writer in diseases

Xie, L., Zhong, X., Cao, W., Liu, J., Zu, X., & Chen, L. (2023) · Molecular Therapy — Nucleic Acids · doi:10.1016/j.omtn.2023.03.023 · Cited by 153 · see citing works

The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence

Varesi, A., Chirumbolo, S., Campagnoli, L. I. M., Pierella, E., Piccini, G. B., Carrara, A., Ricevuti, G., Scassellati, C., Bonvicini, C., & Pascale, A. (2022) · Antioxidants · doi:10.3390/antiox11071224 · Cited by 145 · see citing works

Therapeutic Algorithm for Use of Melatonin in Patients With COVID-19

Reiter, R. J., Abreu-González, P., Marik, P. E., & Domínguez‐Rodríguez, A. (2020) · Frontiers in Medicine · doi:10.3389/fmed.2020.00226 · Cited by 105 · see citing works

The Role and Mechanism of Oxidative Stress and Nuclear Receptors in the Development of NAFLD

Hong, T., Chen, Y., Li, X., & Lü, Y. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/6889533 · Cited by 104 · see citing works

ROR: Nuclear Receptor for Melatonin or Not?

Ma, H., Kang, J., Fan, W., He, H., & Huang, F. P. (2021) · Molecules · doi:10.3390/molecules26092693 · Cited by 81 · see citing works

Nuclear receptors in health and disease: signaling pathways, biological functions and pharmaceutical interventions

Jin, P., Duan, X., Huang, Z., Dong, Y., Zhu, J., Guo, H., Tian, H., Zou, C., & Xie, K. (2025) · Signal Transduction and Targeted Therapy · doi:10.1038/s41392-025-02270-3 · Cited by 86 · see citing works

Epitranscriptomic N4-Acetylcytidine Profiling in CD4+ T Cells of Systemic Lupus Erythematosus

Guo, G., Shi, X., Wang, H., Ye, L., Tong, X., Yan, K., Ding, N., Chen, C., Zhang, H., & Xue, X. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00842 · Cited by 59 · see citing works

Nutraceutical Strategies for Suppressing NLRP3 Inflammasome Activation: Pertinence to the Management of COVID-19 and Beyond

McCarty, M. F., Assanga, S. B. I., Luján, L. M. L., O’Keefe, J. H., & DiNicolantonio, J. J. (2020) · Nutrients · doi:10.3390/nu13010047 · Cited by 54 · see citing works

New insights into the role of melatonin in diabetic cardiomyopathy

Huang, K., Luo, X., Zhong, Y., Deng, L., & Feng, J. (2022) · Pharmacology Research & Perspectives · doi:10.1002/prp2.904 · Cited by 24 · see citing works

Protective actions of vitamin D, anandamide and melatonin during vascular inflammation: Epigenetic mechanisms involved

Giménez, V. M. M., Chuffa, L. G. D. A., Simão, V. A., Reiter, R. J., & Manucha, W. A. (2021) · Life Sciences · doi:10.1016/j.lfs.2021.120191 · Cited by 17 · see citing works

Interpretable machine learning identifies paediatric Systemic Lupus Erythematosus subtypes based on gene expression data

Yones, S. A., Annett, A., Stoll, P., Diamanti, K., Holmfeldt, L., Barrenäs, F., Meadows, J. R. S., & Komorowski, J. (2022) · Scientific Reports · doi:10.1038/s41598-022-10853-1 · Cited by 16 · see citing works

Role of melatonin in mitigation of insulin resistance and ensuing diabetic cardiomyopathy

Nath, A., Ghosh, S., & Bandyopadhyay, D. (2024) · Life Sciences · doi:10.1016/j.lfs.2024.122993 · Cited by 15 · see citing works

Gut microbiota: a novel strategy affecting atherosclerosis

Yang, L., Yang, J., Zhang, T., Xie, X., & Wu, Q. (2025) · Microbiology Spectrum · doi:10.1128/spectrum.00482-24 · Cited by 14 · see citing works

Melatonin, an Antitumor Necrosis Factor Therapy

Álvarez‐López, A. I., Cruz‐Chamorro, I., Lardone, P. J., Bejarano, I., Hinostroza, K. A. A., Ponce‐España, E., Santos‐Sánchez, G., Álvarez‐Sánchez, N., & Carrillo‐Vico, A. (2024) · Journal of Pineal Research · doi:10.1111/jpi.70025 · Cited by 14 · see citing works

Sevoflurane alleviates inflammation, apoptosis and permeability damage of human umbilical vein endothelial cells induced by lipopolysaccharide by inhibiting endoplasmic reticulum stress via upregulating RORα

Ni, W., Zou, Z., Jiang, P., & Wang, S. (2024) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2024.106821 · Cited by 10 · see citing works

Roles of distinct nuclear receptors in diabetic cardiomyopathy

Zheng, Y., Xu, Y., Ji, L., San, W., Shen, D., Zhou, Q., Meng, G., Shi, J., & Chen, Y. (2024) · Frontiers in Pharmacology · doi:10.3389/fphar.2024.1423124 · Cited by 9 · see citing works

Macrophages Unmasked: Their Pivotal Role in Driving Atherosclerosis in Systemic Lupus Erythematosus

Wang, C., Chen, B., Yu, X., & Guan, X. (2025) · Clinical Reviews in Allergy & Immunology · doi:10.1007/s12016-025-09025-6 · Cited by 9 · see citing works

Melatonin levels are low in COVID-19 positive patients and these levels are associated with depression, death anxiety and insomnia

Yılmaz, S. A., & Öner, P. (2023) · Scandinavian Journal of Clinical and Laboratory Investigation · doi:10.1080/00365513.2023.2175236 · Cited by 8 · see citing works

RAR-Related Orphan Receptor: An Accelerated Preeclampsia Progression by Activating the JAK/STAT3 Pathway

Yu, Y., & Zhu, T. (2022) · Yonsei Medical Journal · doi:10.3349/ymj.2022.63.6.554 · Cited by 7 · see citing works

Galactose-modified small molecule modulator targets RORα to enhance circadian rhythm and alleviate periodontitis-associated alveolar bone loss

Feng, G., Liao, Z., Wang, Y., Tang, Q., Li, N., Cheng, L., Liu, Y., Liu, R., Cui, M., Fan, W., et al. (2025) · Bone Research · doi:10.1038/s41413-025-00445-w · Cited by 6 · see citing works

Immunopathogenesis of accelerated atherosclerosis in systemic lupus erythematosus: from innate and adaptive dysregulation to clinical implications

Cao, S., & Wang, C. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1766970 · Cited by 6 · see citing works

Effect of Spermidine on Endothelial Function in Systemic Lupus Erythematosus Mice

Kim, H., & Massett, M. P. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25189920 · Cited by 6 · see citing works

Protective effects of melatonin on AT1, ACE2, and Mas genes expression in induced diabetic aortic rats

Mahmood, N. M. S., Mahmud, A. M. R., & Maulood, I. M. (2024) · Al-mağallaẗ al-ʻirāqiyyaẗ li-l-ʻulūm al-bayṭariyyaẗ/Iraqi journal of veterinary sciences · doi:10.33899/ijvs.2023.144712.3324 · Cited by 5 · see citing works

Systematic Review of Interleukin‐35 in Endothelial Dysfunction: A New Target for Therapeutic Intervention

Li, K., Feng, J., Li, M., Han, L., & Wu, Y. (2025) · Mediators of Inflammation · doi:10.1155/mi/2003124 · Cited by 3 · see citing works

Photobiomodulation in cardiovascular diseases: molecular mechanisms and pharmacological approaches to enhance the therapeutics effects of light

de Moraes, L. H. O., & Buzinari, T. C. (2025) · Lasers in Medical Science · doi:10.1007/s10103-025-04708-0 · Cited by 3 · see citing works

GATA2‑miR‑374a axis promotes vascular smooth muscle cells proliferation, migration via targeting circTADA2A/RORA axis

Tu, W., Feng, M., Zhou, Q., Wang, Y., Wan, M., Gong, D., Li, J., & Du, Y. (2024) · Experimental and Therapeutic Medicine · doi:10.3892/etm.2024.12646 · Cited by 3 · see citing works

The physiological and pathological roles of RNA modifications in T cells

Deng, Y. L., Zhou, J., & Li, H. (2024) · Cell chemical biology · doi:10.1016/j.chembiol.2024.06.003 · Cited by 3 · see citing works

Mitochondrial dysfunction is a potential key mechanism for atherosclerosis predisposition in patients with systemic lupus erythematosus

Liu, X., Wang, C., & Guan, X. (2025) · Journal of Autoimmunity · doi:10.1016/j.jaut.2025.103488 · Cited by 2 · see citing works

Nuclear receptors as therapeutic targets in metabolic and cardiovascular disorders

Li, F., Chen, Q., Dai, Y., & Lu, L. (2025) · iScience · doi:10.1016/j.isci.2025.114042 · Cited by 1 · see citing works

Melatonin attenuates responses to angiotensin II in isolated aortic rings of STZ-induced type 1-like DM rats

Mahmood, N. M. S., Mahmud, A. M. R., & Maulood, I. M. (2024) · Endocrine Research · doi:10.1080/07435800.2024.2445264 · Cited by 1 · see citing works

Mechanisms of interaction of melatonin with lymphocytes

Куклина, Е. М., & Glebezdina, N. S. (2023) · Вестник Пермского университета. Серия: Биология · doi:10.17072/1994-9952-2023-2-195-204

Melatonin: Diagnostic evidence and therapeutic roles in systemic lupus erythematosus

Hosseinzadeh, A., Seirafianpour, F., Sheibani, M., Naeini, A. J., Reiter, R. J., & Mehrzadi, S. (2025) · Current Molecular Pharmacology · doi:10.1016/j.cmp.2025.11.001

Circadian rhythm and the molecular clock in endothelial function of the cardiovascular system

Jiang, Y., Li, T., Tian, Y., Jia, B., Gu, C., Zhang, T., Yang, Y., Zhang, Q., & Yu, G. (2026) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-026-05483-4 · Cited by 1 · see citing works

Development of a prognostic model for sepsis based on gut microbiota-associated genes and identification of potential targets

Li, F., Xu, M., 肖慧勤, Hu, P., & Zhang, W. J. (2026) · Frontiers in Medicine · doi:10.3389/fmed.2026.1766359

RORα: a critical nexus in the crosstalk between cholesterol metabolism and macrophage polarization

Li, D., Liu, G., Wen, X., Zhang, G., Liu, K., Yuan, L., Yu, B., & An, S. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1831854

Mechanisms of Carrageenan-Induced Immune Inflammation and Thrombosis: A Narrative Review

Ma, X., Wu, D., & Huang, R. (2026) · Foods · doi:10.3390/foods15203727

AB0197 Endothelial dysfunction in a mouse model of SLE: A role for tumor necrosis factor-α?

Virdis, A., Tani, C., Vagnani, S., Duranti, E., Bombardieri, S., & Mosca, M. (2012) · Annals of the Rheumatic Diseases · doi:10.1136/annrheumdis-2012-eular.197

Beneficial effects of rapamycin on endothelial function in systemic lupus erythematosus

Kim, H., & Massett, M. P. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1446836 · Cited by 9 · see citing works

Effect of Rapamycin on Endothelial Function in Systemic Lupus Erythematosus (SLE)

Kim, H., & Massett, M. P. (2024) · Physiology · doi:10.1152/physiol.2024.39.s1.632

L-sepiapterin restores SLE serum-induced markers of endothelial function in endothelial cells

Buie, J. N. J., Jenkins, D. P., Muise‐Helmericks, R. C., & Oates, J. C. (2019) · Lupus Science & Medicine · doi:10.1136/lupus-2018-000294 · Cited by 12 · see citing works

Endothelin System Dysregulation as a Driver of Cardiovascular Inflammation and Dysfunction in Systemic Lupus Erythematosus

McCrorey, M. K., Butler, H. M., Lacey, R., Oates, J., Ergul, A., & Beusecum, J. P. V. (2026) · Physiology · doi:10.1152/physiol.2026.41.s1.2300641