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Cited by 389

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Tertiary lymphoid organs in infection and autoimmunity

Open access
Neyt, Katrijn, Perros, Frédéric, GeurtsvanKessel, Corine H., Hammad, Hamida, Lambrecht, Bart N.·2012·Trends in Immunology

Abstract

The lymph nodes (LNs) and spleen have an optimal structure that allows the interaction between T cells, B cells and antigen-presenting dendritic cells (DCs) on a matrix made up by stromal cells. Such a highly organized structure can also be formed in tertiary lymphoid organs (TLOs) at sites of infection or chronic immune stimulation. This review focuses on the molecular mechanisms of TLO formation and maintenance, the controversies surrounding the nature of the inducing events, and the functions of these structures in infection, transplantation and autoimmunity.

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Metadata

Authors
Neyt, K., Perros, F., GeurtsvanKessel, C. H., Hammad, H., & Lambrecht, B. N.
Venue
Trends in Immunology
Publisher
Elsevier BV
Published
2012-06
Volume
33
Issue
6
Pages
297-305
ISSN
1471-4906 (ISSN-L)
OpenAlex
W2030846337
Cited by
389
References
2
FWCI
1.61
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Tertiary lymphoid organs in infection and autoimmunity. https://app.cochat.ai/papers/10.1016/j.it.2012.04.006
The paper
Neyt, K., Perros, F., GeurtsvanKessel, C. H., Hammad, H., & Lambrecht, B. N. (2012). Tertiary lymphoid organs in infection and autoimmunity. Trends in Immunology. https://doi.org/10.1016/j.it.2012.04.006

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.