Cited by 303Child and Adolescent Psychosocial and Emotional DevelopmentAttention Deficit Hyperactivity DisorderPersonality Disorders and Psychopathology

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Adult Outcomes of Childhood Dysregulation: A 14-year Follow-up Study

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Althoff, Robert R., Verhulst, Frank C., Rettew, David C., Hudziak, James J., van der Ende, Jan·2010·Journal of the American Academy of Child & Adolescent Psychiatry

DOI 10.1016/j.jaac.2010.08.006PMC PMC2965164

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Abstract

Objective Using a general population sample, the adult outcomes of children who presented with severe problems with self-regulation defined as being concurrently rated highly on attention problems, aggressive behavior, and anxious-depression on the Child Behavior Checklist-Dysregulation Profile (CBCL-DP) were examined. Method Two thousand seventy-six children from 13 birth cohorts 4 to 16 years of age were drawn from Dutch birth registries in 1983. CBCLs were completed by parents at baseline when children from the different cohorts were 4 to 16 years of age and sampled every 2 years for the next 14 years. At year 14 the CBCL and DSM interview data were collected. Logistic regression was used to compare and contrast outcomes for children with and without dysregulation, as measured by the latent-class-defined CBCL-DP. Sex and age were covaried and concurrent DSM diagnoses were included in regression models. Results Presence of childhood CBCL-DP at wave 1 was associated with increased rates of adult anxiety disorders, mood disorders, disruptive behavior disorders, and drug abuse 14 years later. After controlling for co-occurring disorders in adulthood, associations with anxiety and disruptive behavior disorders with the CBCL-DP remained, whereas the others were not significant. Conclusions A child reported to be in the CBCL-DP class is at increased risk for problems with regulating affect, behavior, and cognition in adulthood.

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Authors: Althoff, R. R., Verhulst, F. C., Rettew, D. C., Hudziak, J. J., & van der Ende, J.
Affiliations: University of Vermont (US)
Erasmus MC (NL)
Corresponding author: Althoff, Robert R.
ORCID: Althoff, Robert R.
Verhulst, Frank C.
Rettew, David C.
Hudziak, James J.
van der Ende, Jan
Venue: Journal of the American Academy of Child & Adolescent Psychiatry
Publisher: Elsevier BV
Published: 2010-11
Volume: 49
Issue: 11
Pages: 1105-1116.e1
ISSN: 0890-8567 (ISSN-L)
DOI: 10.1016/j.jaac.2010.08.006
PMC: PMC2965164
OpenAlex: W2032901980
Cited by: 303
References: 61
Citations by year: 2026: 13 · 2025: 15 · 2024: 23 · 2023: 17 · 2022: 21 · 2021: 23 · 2020: 26 · 2019: 26 · 2018: 24 · 2017: 23 · 2016: 15 · 2015: 17 · 2014: 18 · 2013: 20 · 2012: 10
FWCI: 15.15
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations: Journal of the American Academy of Child & Adolescent Psychiatry (publishedVersion)
PubMed (publishedVersion)
PubMed Central (acceptedVersion)
EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
Funders: National Institute of Mental Health (K08MH082116)
Topics: Social Sciences › Psychology › Clinical Psychology › Child and Adolescent Psychosocial and Emotional Development
Health Sciences › Medicine › Psychiatry and Mental health › Attention Deficit Hyperactivity Disorder
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: adult outcomes, anxiety disorders, mood disorders, disruptive behavior disorders, drug abuse, attention deficits, aggression, anxious depression, latent class analysis, longitudinal follow-up, birth cohort
MeSH terms: Adolescent, Adult, Antisocial Personality Disorder, Behavioral Symptoms, Child, Child Behavior Disorders, Child, Preschool, Female, Follow-Up Studies, Humans, Male, Netherlands, Psychiatric Status Rating Scales, Logistic Models, Outcome Assessment, Health Care, Mood Disorders, Substance-Related Disorders, Young Adult, Checklist

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Adult Outcomes of Childhood Dysregulation: A 14-year Follow-up Study

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