The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
Obesity-Related Differences in Pathomechanism and Outcomes in Patients With HFpEF
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At baseline, the mean LV mass, volumes and ejection fraction were similar to those of a prior CMR study in a HFpEF population.
“At baseline, the mean LV mass, volumes and ejection fraction were similar to those of a prior CMR study in a HFpEF population.16”
From Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure (2025) · cites this paper as [16]
LA diameter, but not volumes, was measured in the latter study, so no comparison can be made.
“LA diameter, but not volumes, was measured in the latter study, so no comparison can be made.”
From Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure (2025) · cites this paper as [16]
In the present study, EAT was lower than that measured in the study by Nakamori et al, whereas paracardiac adipose tissue values were similar to what was termed "EAT" in the latter study.
“In the present study, EAT was lower than that measured in the study by Nakamori et al,16 whereas paracardiac adipose tissue values were similar to what was termed “EAT” in the latter study.”
From Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure (2025) · cites this paper as [16]
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Citations
Cites
Heart Failure With Preserved Ejection Fraction: Mechanisms, Clinical Features, and Therapies
Sharma, K., & Kass, D. A. (2014) · Circulation Research · doi:10.1161/circresaha.115.302922 · Cited by 508
Koepp, K. E., Obokata, M., Reddy, Y. N. V., Olson, T. P., & Borlaug, B. A. (2020) · JACC Heart Failure · doi:10.1016/j.jchf.2020.04.016 · Cited by 269
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Research works printed but not linked: 27
- Paulus, 2007, How to diagnose diastolic heart failure: a consensus statement on the diagnosis of heart failure with normal left ventricular ejection fraction by the Heart Failure and Echocardiography Associations of the European Society of Cardiology, Eur Heart J, 28, 2539, 10.1093/eurheartj/ehm037 · DOI
- Borlaug, 2011, Heart failure with preserved ejection fraction: pathophysiology, diagnosis, and treatment, Eur Heart J, 32, 670, 10.1093/eurheartj/ehq426 · DOI
- Reddy, 2016, Heart failure with preserved ejection fraction, Curr Probl Cardiol, 41, 145, 10.1016/j.cpcardiol.2015.12.002 · DOI
- Owan, 2006, Trends in prevalence and outcome of heart failure with preserved ejection fraction, N Engl J Med, 355, 251, 10.1056/NEJMoa052256 · DOI
- Pfeffer, 2015, Regional variation in patients and outcomes in the treatment of preserved cardiac function heart failure with an aldosterone antagonist (TOPCAT) trial, Circulation, 131, 34, 10.1161/CIRCULATIONAHA.114.013255 · DOI
- Solomon, 2019, Angiotensin-neprilysin inhibition in heart failure with preserved ejection fraction, N Engl J Med, 381, 1609, 10.1056/NEJMoa1908655 · DOI · Paper page
- Shah, 2016, Phenotype-specific treatment of heart failure with preserved ejection fraction, Circulation, 134, 73, 10.1161/CIRCULATIONAHA.116.021884 · DOI · Paper page
- Lindman, 2014, Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study, J Am Coll Cardiol, 64, 541, 10.1016/j.jacc.2014.05.030 · DOI · Paper page
- Samson, 2016, Clinical phenotypes in heart failure with preserved ejection fraction, J Am Heart Assoc, 5, 1
- Borlaug, 2017, Is it time to recognize a new phenotype? heart failure with preserved ejection fraction with pulmonary vascular disease, Eur Heart J, 38, 2874, 10.1093/eurheartj/ehx184 · DOI
- Obokata, 2017, Evidence supporting the existence of a distinct obese phenotype of heart failure with preserved ejection fraction, Circulation, 136, 6, 10.1161/CIRCULATIONAHA.116.026807 · DOI · Paper page
- Kresoja, 2021, Proteomics to improve phenotyping in obese patients with heart failure with preserved ejection fraction, Eur J Heart Fail, 23, 1633, 10.1002/ejhf.2291 · DOI
- Redfield, 2013, Effect of phosphodiesterase-5 inhibition on exercise capacity and clinical status in heart failure with preserved ejection fraction: a randomized clinical trial, JAMA, 309, 1268, 10.1001/jama.2013.2024 · DOI
- Chahal, 2012, Obesity and right ventricular structure and function: the MESA-right ventricle study, Chest, 141, 388, 10.1378/chest.11-0172 · DOI
- Wong, 2006, Association of subclinical right ventricular dysfunction with obesity, J Am Coll Cardiol, 47, 611, 10.1016/j.jacc.2005.11.015 · DOI · Paper page
- Mazurek, 2003, Human epicardial adipose tissue is a source of inflammatory mediators, Circulation, 108, 2460, 10.1161/01.CIR.0000099542.57313.C5 · DOI · Paper page
- van Woerden, 2022, Epicardial adipose tissue and outcome in heart failure with mid-range and preserved ejection fraction, Circ Heart Fail, 15, 10.1161/CIRCHEARTFAILURE.121.009238 · DOI
- Borlaug, 2019, The role of the pericardium in heart failure: implications for pathophysiology and treatment, J Am Coll Cardiol HF, 7, 574
- Ponikowski, 2016, Eur Heart J, 37, 2129, 10.1093/eurheartj/ehw128 · DOI · Paper page
- Heidenreich, 2022, 2022 AHA/ACC/HFSA guideline for the management of heart failure: a report of the American College of Cardiology/American Heart Association Joint Committee on clinical practice guidelines, J Am Coll Cardiol, 79, e263, 10.1016/j.jacc.2021.12.012 · DOI · Paper page
- Chen, 2001, Noninvasive single-beat determination of left ventricular end-systolic elastance in humans, J Am Coll Cardiol, 38, 2028, 10.1016/S0735-1097(01)01651-5 · DOI
- Ky, 2013, Ventricular-arterial coupling, remodeling, and prognosis in chronic heart failure, J Am Coll Cardiol, 62, 1165, 10.1016/j.jacc.2013.03.085 · DOI
- Anand, 2021, Prognostic value of peak stress cardiac power in patients with normal ejection fraction undergoing exercise stress echocardiography, Eur Heart J, 42, 776, 10.1093/eurheartj/ehaa941 · DOI
- Obokata, 2019, Deterioration in right ventricular structure and function over time in patients with heart failure and preserved ejection fraction, Eur Heart J, 40, 689, 10.1093/eurheartj/ehy809 · DOI
- Maniar, 2003, Impact of pericardial restraint on right atrial mechanics during acute right ventricular pressure load, Am J Physiol Heart Circ Physiol, 284, H350, 10.1152/ajpheart.00444.2002 · DOI
- Tyberg, 1986, The relationship between pericardial pressure and right atrial pressure: an intraoperative study, Circulation, 73, 428, 10.1161/01.CIR.73.3.428 · DOI
- Ryan, 1985, An echocardiographic index for separation of right ventricular volume and pressure overload, J Am Coll Cardiol, 5, 918, 10.1016/S0735-1097(85)80433-2 · DOI
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Sorted by citations
Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure
Kramer, C. M., Borlaug, B. A., Zile, M. R., Ruff, D., DiMaria, J. M., Menon, V., Ou, Y., Zarante, A. M., Hurt, K. C., Murakami, M., et al. (2025) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2024.11.001 · Cited by 200
Metadata
- Authors
- Nakamori, S., Kucukseymen, S., Rodriguez, J., Yazdanian, F., Ngo, L. H., Gopal, D. M., Manning, W. J., & Nezafat, R.
- ORCID
- Gopal, Deepa M.
- Venue
- JACC: Advances
- Publisher
- Elsevier BV
- Published
- 2023-12
- Volume
- 2
- Issue
- 10
- Pages
- 100730
- ISSN
- 2772-963X
- PMC
- PMC11198377
- Cited by
- 11
- References
- 2
- Language
- en
- Licence
- Funders
- National Institutes of Health (R01 HL127015, R01 HL129157, R01 HL129185, R01 HL154744, R01 HL158098)
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