The DOI matches its Crossref record; 64 of the 64 references it cites were found in a registry or an index.
Radiation-Induced Endothelial Vascular Injury
Open accessAbstract
In radiation therapy for cancer, the therapeutic ratio represents an optimal balance between tumor control and normal tissue complications. As improvements in the therapeutic arsenal against cancer extend longevity, the importance of late effects of radiation increases, particularly those caused by vascular endothelial injury. Radiation both initiates and accelerates atherosclerosis, leading to vascular events like stroke, coronary artery disease, and peripheral artery disease. Increased levels of proinflammatory cytokines in the blood of long-term survivors of the atomic bomb suggest that radiation evokes a systemic inflammatory state responsible for chronic vascular side effects. In this review, the authors offer an overview of potential mechanisms implicated in radiation-induced vascular injury.
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Cites
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Cited by
De Ruysscher, D., Niedermann, G., Burnet, N. G., Siva, S., Lee, A. W. M., & Hegi-Johnson, F. (2019) · Nature Reviews Disease Primers · doi:10.1038/s41572-019-0064-5 · Cited by 868
Choi, Y. Y., Kim, A., Lee, Y., Lee, Y. H., Park, M., Shin, E., Park, S., Youn, B., & Seong, K. M. (2023) · Journal of Extracellular Vesicles · doi:10.1002/jev2.12325 · Cited by 44
Radiotherapy and radiosensitization in breast cancer: Molecular targets and clinical applications
Bhat, V., Pellizzari, S., Allan, A. L., Wong, E., Lock, M., Brackstone, M., Lohmann, A. E., Cescon, D. W., & Parsyan, A. (2022) · Critical Reviews in Oncology/Hematology · doi:10.1016/j.critrevonc.2021.103566 · Cited by 31
Metadata
- Authors
- Venkatesulu, B. P., Mahadevan, L. S., Aliru, M. L., Yang, X., Bodd, M. H., Singh, P. K., Yusuf, S. W., Abe, J.-I., & Krishnan, S.
- Venue
- JACC: Basic to Translational Science
- Publisher
- Elsevier BV
- Published
- 2018-08
- Volume
- 3
- Issue
- 4
- Pages
- 563-572
- ISSN
- 2452-302X (ISSN-L)
- OpenAlex
- W2889239000
- Cited by
- 334
- References
- 64
- FWCI
- 13.86
- Type
- journal article
- Language
- en
- Open access
- gold
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- Venkatesulu, B. P., Mahadevan, L. S., Aliru, M. L., Yang, X., Bodd, M. H., Singh, P. K., Yusuf, S. W., Abe, J.-I., & Krishnan, S. (2018). Radiation-Induced Endothelial Vascular Injury. JACC: Basic to Translational Science. https://doi.org/10.1016/j.jacbts.2018.01.014
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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