The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Measurement of the Interleukin Family Member ST2 in Patients With Acute Dyspnea
Open accessAbstract
OBJECTIVES The aim of this study was to examine the value of measurement of the interleukin-1 receptor family member ST2 in patients with dyspnea. BACKGROUND Concentrations of ST2 have been reported to be elevated in patients with heart failure (HF). METHODS Five hundred ninety-three dyspneic patients with and without acute destabilized HF presenting to an urban emergency department were evaluated with measurements of ST2 concentrations. Independent predictors of death at 1 year were identified. RESULTS Concentrations of ST2 were higher among those with acute HF compared with those without (0.50 vs. 0.15 ng/ml; p < 0.001), although amino-terminal pro-brain natriuretic peptide (NT-proBNP) was superior to ST2 for diagnosis of acute HF. Median concentrations of ST2 at presentation to the emergency department were higher among decedents than survivors at 1 year (1.08 vs. 0.18 ng/ml; p < 0.001), and in multivariable analyses, an ST2 concentration > or =0.20 ng/ml strongly predicted death at 1 year in dyspneic patients as a whole (HR = 5.6, 95% confidence interval [CI] 2.2 to 14.2; p < 0.001) as well as those with acute HF (hazard ratio [HR] = 9.3, 95% CI 1.3 to 17.8; p = 0.03). This risk associated with an elevated ST2 in dyspneic patients with and without HF appeared early and was sustained at 1 year after presentation (log-rank p value <0.001). A multi-marker approach with both ST2 and NT-proBNP levels identified subjects with the highest risk for death. CONCLUSIONS Among dyspneic patients with and without acute HF, ST2 concentrations are strongly predictive of mortality at 1 year and might be useful for prognostication when used alone or together with NT-proBNP.
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Rapid Measurement of B-Type Natriuretic Peptide in the Emergency Diagnosis of Heart Failure
Maisel, A. S., Krishnaswamy, P., Nowak, R. M., McCord, J., Hollander, J. E., Duc, P., Omland, T., Storrow, A. B., Abraham, W. T., Wu, A. H. B., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa020233 · Cited by 3,362
Self-citationThe N-terminal Pro-BNP Investigation of Dyspnea in the Emergency department (PRIDE) study
Januzzi, J. L., Camargo, C. A., Anwaruddin, S., Baggish, A. L., Chen, A. A., Krauser, D. G., Tung, R., Cameron, R., Nagurney, J. T., Chae, C. U., et al. (2005) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2004.12.032 · Cited by 1,207
Self-citationCarriere, V., Roussel, L., Ortega, N., Lacorre, D.-A., Americh, L., Aguilar, L., Bouche, G., & Girard, J.-P. (2007) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0606854104 · Cited by 966
Sabatine, M. S., Morrow, D. A., de Lemos, J. A., Gibson, C. M., Murphy, S. A., Rifai, N., McCabe, C., Antman, E. M., Cannon, C. P., & Braunwald, E. (2002) · Circulation · doi:10.1161/01.cir.0000015464.18023.0a · Cited by 735
Weinberg, E. O., Shimpo, M., De Keulenaer, G. W., MacGillivray, C., Tominaga, S.-I., Solomon, S. D., Rouleau, J.-L., & Lee, R. T. (2002) · Circulation · doi:10.1161/01.cir.0000038705.69871.d9 · Cited by 645
Identification of Serum Soluble ST2 Receptor as a Novel Heart Failure Biomarker
Weinberg, E. O., Shimpo, M., Hurwitz, S., Tominaga, S.-I., Rouleau, J.-L., & Lee, R. T. (2003) · Circulation · doi:10.1161/01.cir.0000047274.66749.fe · Cited by 503
Brint, E. K., Xu, D., Liu, H., Dunne, A., McKenzie, A. N. J., O'Neill, L. A. J., & Liew, F. Y. (2004) · Nature Immunology · doi:10.1038/ni1050 · Cited by 489
Baekkevold, E. S., Roussigné, M., Yamanaka, T., Johansen, F.-E., Jahnsen, F. L., Amalric, F., Brandtzaeg, P., Erard, M., Haraldsen, G., & Girard, J.-P. (2003) · The American Journal of Pathology · doi:10.1016/s0002-9440(10)63631-0 · Cited by 474
Cited by
2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.019 · Cited by 12,536
Self-citation2017 ACC/AHA/HFSA Focused Update of the 2013 ACCF/AHA Guideline for the Management of Heart Failure
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2017) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.04.025 · Cited by 3,418
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8807 · Cited by 3,304
Self-citationYancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Colvin, M. M., Drazner, M. H., Filippatos, G. S., Fonarow, G. C., Givertz, M. M., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000509 · Cited by 3,109
Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8776 · Cited by 2,106
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Metadata
- Authors
- Januzzi, J. L., Peacock, W. F., Maisel, A. S., Chae, C. U., Jesse, R. L., Baggish, A. L., O’Donoghue, M., Sakhuja, R., Chen, A. A., van Kimmenade, R. R. J., Lewandrowski, K. B., Lloyd-Jones, D. M., & Wu, A. H. B.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2007-08
- Volume
- 50
- Issue
- 7
- Pages
- 607-613
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W58536052
- Cited by
- 522
- References
- 21
- FWCI
- 12.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Januzzi, J. L., Peacock, W. F., Maisel, A. S., Chae, C. U., Jesse, R. L., Baggish, A. L., O’Donoghue, M., Sakhuja, R., Chen, A. A., van Kimmenade, R. R. J., Lewandrowski, K. B., Lloyd-Jones, D. M., & Wu, A. H. B. (2007). Measurement of the Interleukin Family Member ST2 in Patients With Acute Dyspnea. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2007.05.014
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