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Cited by 236Congenital Heart Disease StudiesCardiac and Coronary Surgery TechniquesCardiovascular Conditions and Treatments

The DOI matches its Crossref record; 35 of the 36 references it cites were found in a registry or an index.

Causes of Late Deaths After Pediatric Cardiac Surgery

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Nieminen, Heta P., Jokinen, Eero V., Sairanen, Heikki I.·2007·Journal of the American College of Cardiology
DOI 10.1016/j.jacc.2007.05.040
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Abstract

Objectives We examined the causes and modes of late death after pediatric cardiac surgery.Background The late mortality of patients operated on for congenital heart defect (CHD) is comprehensively unexamined. In this study, the causes of death were examined to obtain further knowledge of the morbidity of the patients.Methods We studied all late deaths of patients operated on for CHD in Finland during the years 1953 to 1989. We calculated the survival of patients, identified the causes of deaths from death certificates, and examined the modes of CHD-related deaths. We compared the survival and the causes of non-CHD-related deaths to those of the general population.Results Of the 6,024 patients who survived their first operation, 592 (9%) died during the 45-year follow-up period. The progress of treatment was seen in the survival of the patients operated on in different decades. The cause of death was confirmed with postmortem examination in 474 (81%) cases. The majority of patients (397, 67%) died owing to the CHD. Furthermore, non-CHD-related mortality was twice as high (risk ratio 1.9, 95% confidence interval 1.5 to 2.4) as expected. The main mode for CHD-related death was heart failure (40%). Other modes included perioperative (26%), sudden (22%), and cardiovascular (12%) deaths. The number of deaths caused by neurological and respiratory diseases was higher and the number of accidental deaths was lower than expected.Conclusions The survival of patients was lower than that of the general population (relative 45-year survival 89%). Most patients died owing to CHDs, but non-CHD-related mortality was also high.

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  1. Morris, 1991, 25-year mortality after surgical repair of congenital heart defect in childhood, JAMA, 266, 3447, 10.1001/jama.1991.03470240069035 · DOI

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Metadata

Authors
Nieminen, H. P., Jokinen, E. V., & Sairanen, H. I.
Affiliations
Helsinki University Hospital (FI)
ORCID
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2007-09
Volume
50
Issue
13
Pages
1263-1271
ISSN
0735-1097 (ISSN-L)
DOI
10.1016/j.jacc.2007.05.040
OpenAlex
W61894324
Cited by
236
References
36
Citations by year
2026: 5 · 2025: 8 · 2024: 11 · 2023: 7 · 2022: 6 · 2021: 15 · 2020: 10 · 2019: 10 · 2018: 23 · 2017: 24 · 2016: 12 · 2015: 16 · 2014: 15 · 2013: 15 · 2012: 14
FWCI
6.88
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Congenital Heart Disease Studies
  • Health Sciences › Medicine › Surgery › Cardiac and Coronary Surgery Techniques
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Cardiovascular Conditions and Treatments
Keywords
late mortality, pediatric cardiac surgery, congenital heart disease, causes of death, heart failure, long-term survival, sudden death, neurological disorders, accidental death, cardiovascular mortality
MeSH terms
Accidents, Adolescent, Cause of Death, Child, Child, Preschool, Death, Sudden, Female, Finland, Heart Defects, Congenital, Heart Failure, Humans, Infant, Infant, Newborn, Male, Postoperative Complications, Registries, Suicide, Survival Analysis, Sex Distribution

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