Cited by 201Cardiac pacing and defibrillation studiesCardiac electrophysiology and arrhythmiasCardiac Arrhythmias and Treatments

The DOI matches its Crossref record; 29 of the 30 references it cites were found in a registry or an index.

Does Microvolt T-Wave Alternans Testing Predict Ventricular Tachyarrhythmias in Patients With Ischemic Cardiomyopathy and Prophylactic Defibrillators?

Open access

Chow, Theodore, Kereiakes, Dean J., Onufer, John, Woelfel, Alan, Gursoy, Sinan, Peterson, Brett J., Brown, Mark L., Pu, Wenji, Benditt, David G.·2008·Journal of the American College of Cardiology

DOI 10.1016/j.jacc.2008.08.018

Open this paper in CoChat — free account

Abstract

Objectives The purpose of this trial was to determine whether microvolt T-wave alternans (MTWA) predicts ventricular tachyarrhythmic events (VTEs) in post-myocardial infarction patients with left ventricular ejection fraction (LVEF) < or =30%.Background Previous studies have established MTWA as a predictor for total and arrhythmic mortality, but its ability to identify prophylactic implantable cardioverter-defibrillator (ICD) recipients most likely to experience VTEs remains uncertain.Methods This prospective trial was conducted at 50 U.S. centers. Patients were eligible if they met MADIT-II (Multicenter Automatic Defibrillator Implantation Trial II) indications for device implant. All patients underwent MTWA testing followed by ICD implantation, with pre-specified programming to minimize the likelihood of therapies for non-life-threatening VTE. Minimum follow-up was 2 years with annual MTWA testing. Initially indeterminate MTWA tests were repeated.Results Analyses were conducted on 575 patients (84% male; average age +/- SD = 65 +/- 11 years; average LVEF +/- SD = 0.24 +/- 0.05). The final distribution of MTWA results were: MTWA positive in 293 (51%), MTWA negative in 214 (37%), and indeterminate in 68 patients (12%). Over an average follow-up of 2.1 +/- 0.9 years, there were 70 VTEs. A VTE occurred in 48 of 361 (13%, 6.3%/year) MTWA non-negative and 22 of 214 (10%, 5.0%/year) MTWA negative patients. A non-negative MTWA test result was not associated with VTE (hazard ratio: 1.26; 95% confidence interval: 0.76 to 2.09; p = 0.37), although total mortality was significantly increased (hazard ratio: 2.04; 95% confidence interval: 1.10 to 3.78; p = 0.02).Conclusions In MADIT-II-indicated ICD-treated patients, the risk of VTE does not differ according to MTWA classification, despite differences in total mortality. (MASTER I-Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients; NCT00305240).

Integrity signals

Registry

Crossref · 10.1016/j.jacc.2008.08.018

Cites

29 of 29 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1992) · Springer series in statistics · doi:10.1007/978-1-4612-4380-9_25 · Cited by 45,239
Regression Models and Life-Tables
Cox, D. R. (1972) · Journal of the Royal Statistical Society Series B: Statistical Methodology · doi:10.1111/j.2517-6161.1972.tb00899.x · Cited by 39,793
Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Regression Models and Life-Tables
Cox, D. R. (1992) · Springer Series in Statistics · doi:10.1007/978-1-4612-4380-9_37 · Cited by 26,297
Prophylactic Implantation of a Defibrillator in Patients with Myocardial Infarction and Reduced Ejection Fraction
Moss, A. J., Zaręba, W., Hall, W. J., Klein, H., Wilber, D. J., Cannom, D. S., Daubert, J. P., Higgins, S. L., Brown, M. W., & Andrews, M. L. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa013474 · Cited by 6,885
Self-citation
Amiodarone or an Implantable Cardioverter–Defibrillator for Congestive Heart Failure
Bardy, G. H., Lee, K. L., Mark, D. B., Poole, J. E., Packer, D. L., Boineau, R., Domanski, M., Troutman, C., Anderson, J., Johnson, G., et al. (2005) · New England Journal of Medicine · doi:10.1056/nejmoa043399 · Cited by 6,552
Improved Survival with an Implanted Defibrillator in Patients with Coronary Disease at High Risk for Ventricular Arrhythmia
Moss, A. J., Hall, W. J., Cannom, D. S., Daubert, J. P., Higgins, S. L., Klein, H., Levine, J. H., Saksena, S., Waldo, A. L., Wilber, D., et al. (1996) · New England Journal of Medicine · doi:10.1056/nejm199612263352601 · Cited by 4,165
Self-citation
Heart Disease and Stroke Statistics—2008 Update
Writing Group Members, Rosamond, W. D., Flegal, K. M., Furie, K. L., Go, A. S., Greenlund, K. J., Haase, N., Hailpern, S. M., Ho, M., Howard, V. J., et al. (2007) · Circulation · doi:10.1161/circulationaha.107.187998 · Cited by 3,799
A Randomized Study of the Prevention of Sudden Death in Patients with Coronary Artery Disease
Buxton, A. E., Lee, K. L., Fisher, J. D., Josephson, M. E., Prystowsky, E. N., & Hafley, G. (1999) · New England Journal of Medicine · doi:10.1056/nejm199912163412503 · Cited by 2,489
PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION
Oss, J. M., Areba, W. O. Z., Ackson, W. J., Lein, H. E. K., Ilber, D. A. J. W., Annom, D. A. S. C., Ames, J. M., Aubert, P., Iggins, S. T. L. H., Rown, M. A. W. B., et al. (2002) · Cited by 2,026

Flagged first, then by citations

Show all 30 references

1 of the 30 references couldn’t be matched to a known paper.

Research works printed but not linked: 2

Gold, 2006, T-wave alternans SCD HeFT study: primary endpoint analysis, Circulation, 114, II428
Costantini, 2006, The Alternans Before Cardioverter Defibrillator (ABCD) Trial: a noninvasive strategy for primary prevention of sudden cardiac death using T-wave alternans, Circulation, 114, 2426

Sorted by citations

2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
Al‐Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T. M., Field, M. E., Fonarow, G. C., et al. (2018) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2017.10.054 · Cited by 1,902
2017 AHA/ACC/HRS Guideline for Management of Patients With Ventricular Arrhythmias and the Prevention of Sudden Cardiac Death
Al‐Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T. M., Field, M. E., Fonarow, G. C., et al. (2017) · Circulation · doi:10.1161/cir.0000000000000549 · Cited by 771
2017 AHA/ACC/HRS guideline for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death
Al‐Khatib, S. M., Stevenson, W. G., Ackerman, M. J., Bryant, W. J., Callans, D. J., Curtis, A. B., Deal, B. J., Dickfeld, T. M., Field, M. E., Fonarow, G. C., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.10.036 · Cited by 644
Sudden Cardiac Death Prediction and Prevention
Fishman, G. I., Chugh, S. S., Dimarco, J., Albert, C. M., Anderson, M. E., Bonow, R. O., Buxton, A. E., Chen, P., Estes, M., Jouven, X., et al. (2010) · Circulation · doi:10.1161/circulationaha.110.976092 · Cited by 633
Untitled work
Verrier (2011) · doi:10.1016/j.jacc.2011.06.029 · Cited by 421
2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry
Steinberg, J. S., Varma, N., Cygankiewicz, I., Aziz, P., Balsam, P., Baranchuk, A., Cantillon, D. J., Dilaveris, P., Dubner, S. J., El-Sherif, N., et al. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2017.03.038 · Cited by 303
Fragmented QRS on twelve-lead electrocardiogram predicts arrhythmic events in patients with ischemic and nonischemic cardiomyopathy
Das, M. K., Maskoun, W., Shen, C., Michael, M. A., Suradi, H. S., Desai, M., Subbarao, R., & Bhakta, D. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.09.065 · Cited by 279
Prediction of fatal or near-fatal cardiac arrhythmia events in patients with depressed left ventricular function after an acute myocardial infarction
Huikuri, H. V., Raatikainen, M. J. P., Moerch-Joergensen, R., Hartikainen, J., Virtanen, V., Boland, J., Anttonen, O., Hoest, N., Boersma, L. V. A., Platou, E. S., et al. (2008) · European Heart Journal · doi:10.1093/eurheartj/ehn537 · Cited by 264
Chronic Heart Failure: Contemporary Diagnosis and Management
Ramani, G. V., Uber, P. A., & Mehra, M. R. (2010) · Mayo Clinic Proceedings · doi:10.4065/mcp.2009.0494 · Cited by 243
Acute Coronary Syndrome
Scirica, B. M. (2010) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2009.09.071 · Cited by 230
Risk stratification after myocardial infarction: is left ventricular ejection fraction enough to prevent sudden cardiac death?
Dagres, N., & Hindricks, G. (2013) · European Heart Journal · doi:10.1093/eurheartj/eht109 · Cited by 169
Risk Stratification for Sudden Cardiac Death
Goldberger, J. J., Basu, A., Boineau, R., Buxton, A. E., CAIN, M. E., Canty, J. M., Chen, P., Chugh, S. S., Costantini, O., Exner, D. V., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.007149 · Cited by 143
Sudden Cardiac Death Early After Myocardial Infarction
Zaman, S. J., & Kovoor, P. (2014) · Circulation · doi:10.1161/circulationaha.113.007497 · Cited by 126
Nonsustained Ventricular Tachycardia
Katritsis, D. G., Zaręba, W., & Camm, A. J. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2011.12.063 · Cited by 123
2017 ISHNE-HRS expert consensus statement on ambulatory ECG and external cardiac monitoring/telemetry
Steinberg, J. S., Varma, N., Cygankiewicz, I., Aziz, P. F., Balsam, P., Baranchuk, A. M., Cantillon, D. J., Dilaveris, P., Dubner, S., El‐Sherif, N., et al. (2017) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12447 · Cited by 123
Basis for sudden cardiac death prediction by T-wave alternans from an integrative physiology perspective
Verrier, R. L., Kumar, K., & Nearing, B. D. (2008) · Heart Rhythm · doi:10.1016/j.hrthm.2008.11.019 · Cited by 103
JCS 2018 Guideline on Diagnosis of Chronic Coronary Heart Diseases
Yamagishi, M., Tamaki, N., Akasaka, T., Ikeda, T., Ueshima, K., Uemura, S., Otsuji, Y., Kihara, Y., Kimura, K., Kimura, T., et al. (2021) · Circulation Journal · doi:10.1253/circj.cj-19-1131 · Cited by 100
Are complications of implantable defibrillators under-estimated and benefits over-estimated?
Brignole, M. (2009) · EP Europace · doi:10.1093/europace/eup174 · Cited by 69
JCS/JHRS 2022 Guideline on Diagnosis and Risk Assessment of Arrhythmia
Takase, B., Ikeda, T., Shimizu, W., Abe, H., Aiba, T., Chinushi, M., Koba, S., KUSANO, K. F., Niwano, S., Takahashi, N., et al. (2023) · Circulation Journal · doi:10.1253/circj.cj-22-0827 · Cited by 68
Risk stratification for sudden death in patients with coronary artery disease
Buxton, A. E. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.02.016 · Cited by 58
Post-Exercise Assessment of Cardiac Repolarization Alternans in Patients With Coronary Artery Disease Using the Modified Moving Average Method
Slawnych, M., Nieminen, T. V. M., Kähönen, M. A. P., Kavanagh, K. M., Lehtimäki, T. J., Ramadan, D., Viik, J., Aggarwal, S., Lehtinen, R., Ellis, L., et al. (2009) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2008.12.026 · Cited by 58
Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling
Bayer, J. D., Narayan, S. M., Lalani, G., & Trayanova, N. A. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.04.008 · Cited by 57
Sudden Cardiac Risk Stratification with Electrocardiographic Indices - A Review on Computational Processing, Technology Transfer, and Scientific Evidence
Gimeno-Blanes, F.-J., Blanco–Velasco, M., Barquero‐Pérez, Ó., Garcı́a-Alberola, A., & Rojo‐Álvarez, J. L. (2016) · Frontiers in Physiology · doi:10.3389/fphys.2016.00082 · Cited by 58
Clinical utility of microvolt T-wave alternans testing in identifying patients at high or low risk of sudden cardiac death
Merchant, F. M., Ikeda, T., Pedretti, R. F. E., Salerno‐Uriarte, J. A., Chow, T., Chan, P. S., Bartone, C. L., Hohnloser, S. H., Cohen, R. J., & Armoundas, A. A. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2012.03.014 · Cited by 56
Self-citation
Do Beta‐Blockers Impact Microvolt T‐Wave Alternans Testing in Patients at Risk for Ventricular Arrhythmias? A Meta‐Analysis
Chan, P. S.-F., GOLD, M. R., & Nallamothu, B. K. (2010) · Journal of Cardiovascular Electrophysiology · doi:10.1111/j.1540-8167.2010.01757.x · Cited by 56
Comparative analysis of methods for automatic detection and quantification of microvolt T-wave alternans
Burattini, L., Bini, S., & Burattini, R. (2009) · Medical Engineering & Physics · doi:10.1016/j.medengphy.2009.08.009 · Cited by 56
Risk Stratification for Sudden Cardiac Death After Myocardial Infarction
Waks, J. W., & Buxton, A. E. (2018) · Annual Review of Medicine · doi:10.1146/annurev-med-041316-090046 · Cited by 58
Prediction of sudden arrhythmic death following acute myocardial infarction
Liew, R. (2010) · Heart · doi:10.1136/hrt.2010.194407 · Cited by 54
Role of Substrate and Triggers in the Genesis of Cardiac Alternans, From the Myocyte to the Whole Heart
Merchant, F. M., & Armoundas, A. A. (2012) · Circulation · doi:10.1161/circulationaha.111.033563 · Cited by 53
Exercise Testing in Nonatherosclerotic Heart Disease
Morise, A. P. (2011) · Circulation · doi:10.1161/circulationaha.109.914762 · Cited by 51
Surface Electrocardiogram Predictors of Sudden Cardiac Arrest.
Abdelghani, S. A., Rosenthal, T. M., & Morin, D. P. (2016) · PubMed Central · Cited by 49
Usefulness of T‐Wave Alternans in Sudden Death Risk Stratification and Guiding Medical Therapy
Nieminen, T. V. M., & Verrier, R. L. (2010) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.2010.00376.x · Cited by 48
Prospective Observational Study of Implantable Cardioverter‐Defibrillators in Primary Prevention of Sudden Cardiac Death: Study Design and Cohort Description
Cheng, A., Dalal, D., Butcher, B., Norgard, S., Zhang, Y., Dickfeld, T. M., ELDADAH, Z. A., Ellenbogen, K. A., Güallar, E., & Tomaselli, G. F. (2013) · Journal of the American Heart Association · doi:10.1161/jaha.112.000083 · Cited by 47
Risk Stratification of Sudden Cardiac Death in Patients with Heart Failure: An update
Masarone, D., Limongelli, G., Ammendola, E., Verrengia, M., Gravino, R., & Pacileo, G. (2018) · Journal of Clinical Medicine · doi:10.3390/jcm7110436 · Cited by 45
Crescendo in Depolarization and Repolarization Heterogeneity Heralds Development of Ventricular Tachycardia in Hospitalized Patients With Decompensated Heart Failure
Nearing, B. D., Wellenius, G. A., Mittleman, M. A., Josephson, M. E., Burger, A. J., & Verrier, R. L. (2011) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.111.965434 · Cited by 42
From evidence-based medicine to digital twin technology for predicting ventricular tachycardia in ischaemic cardiomyopathy
de Lepper, A. G. W., Buck, C. M. A., Veer, M. V. ’., Huberts, W., van de Vosse, F. N., & Dekker, L. (2022) · Journal of The Royal Society Interface · doi:10.1098/rsif.2022.0317 · Cited by 40
Alternans of action potential duration and amplitude in rabbits with left ventricular dysfunction following myocardial infarction
Myles, R. C., Burton, F. L., Cobbe, S. M., & Smith, G. L. (2010) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2010.11.019 · Cited by 40
Ability of microvolt T-wave alternans to modify risk assessment of ventricular tachyarrhythmic events: A meta-analysis
Gupta, A., Hoang, D. D., Karliner, L., Tice, J. A., Heidenreich, P. A., Wang, P. J., & Turakhia, M. P. (2012) · American Heart Journal · doi:10.1016/j.ahj.2011.11.021 · Cited by 39
Arrhythmic sudden cardiac death: substrate, mechanisms and current risk stratification strategies for the post-myocardial infarction patient.
Αρσένος, Π., Gatzoulis, K. A., Dilaveris, P., Manis, G., Tsiachris, D., Archontakis, S., Vouliotis, A.-I., Vouliotis, A. H., Sideris, S. K., & Stefanadis, C. (2013) · PubMed · Cited by 36
Sudden cardiac death in adults with congenital heart disease
Yap, S., & Harris, L. (2009) · Expert Review of Cardiovascular Therapy · doi:10.1586/erc.09.153 · Cited by 35
Sudden Death Risk-Stratification in 2018–2019: The Old and the New
Zaman, S. J., Goldberger, J. J., & Kovoor, P. (2018) · Heart Lung and Circulation · doi:10.1016/j.hlc.2018.08.027 · Cited by 36
Predicting the Future
PASSMAN, R. S., & Goldberger, J. J. (2012) · Circulation · doi:10.1161/circulationaha.111.023879 · Cited by 34
Sudden Cardiac Death in Heart Failure
Klein, L., & Hsia, H. H. (2013) · Cardiology Clinics · doi:10.1016/j.ccl.2013.09.008 · Cited by 32
Effect of Empagliflozin Versus Placebo on Cardiac Sympathetic Activity in Acute Myocardial Infarction Patients with Type 2 Diabetes Mellitus: Rationale
Kubota, Y., Yamamoto, T., Tara, S., Tokita, Y., Yodogawa, K., Iwasaki, Y., Takano, H., Tsukada, Y. T., Asai, K., Miyamoto, M., et al. (2018) · Diabetes Therapy · doi:10.1007/s13300-018-0480-7 · Cited by 33
Electrocardiogram‐Based Predictors of Sudden Cardiac Death in Patients With Coronary Artery Disease
Liew, R. (2011) · Clinical Cardiology · doi:10.1002/clc.20924 · Cited by 34
Risk stratification for sudden cardiac death: Is there a clinical role for T wave alternans?
Cutler, M. J., & ROSENBAUM, D. S. (2009) · Heart Rhythm · doi:10.1016/j.hrthm.2009.05.025 · Cited by 32
Risk Stratification of Sudden Cardiac Death After Acute Myocardial Infarction
Bui, A. H., & Waks, J. W. (2018) · Journal of Innovations in Cardiac Rhythm Management · doi:10.19102/icrm.2018.090201 · Cited by 36
Microvolt T-wave alternans and electrophysiologic testing predict distinct arrhythmia substrates: Implications for identifying patients at risk for sudden cardiac death
Amit, G., ROSENBAUM, D. S., Super, D. M., & Costantini, O. (2010) · Heart Rhythm · doi:10.1016/j.hrthm.2010.02.012 · Cited by 31
Guidelines for Risks and Prevention of Sudden Cardiac Death (JCS 2010)
JCS Joint Working Group (2012) · Circulation Journal · doi:10.1253/circj.cj-88-0022 · Cited by 31
Profile of Microvolt T-Wave Alternans Testing in 1003 Patients Hospitalized with Heart Failure
Jackson, C. E., Myles, R. C., Tsorlalis, I. K., Dalzell, J. R., Spooner, R. J., Rodgers, J. R., Bezlyak, V., Greenlaw, N., Ford, I., Cobbe, S. M., et al. (2012) · European Journal of Heart Failure · doi:10.1093/eurjhf/hfs010 · Cited by 29
Prediction of sudden cardiac death in patients after acute myocardial infarction using T-wave alternans: a prospective study
Yu, H., Fang, P., Wu, Y., Li, X., Jun, L., Li, Z., Sen, L., & Zhang, S. (2011) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2011.07.015 · Cited by 29
T-Wave Alternans as an Arrhythmic Risk Stratifier: State of the Art
Merchant, F. M., Sayadi, O., Moazzami, K., Puppala, D., & Armoundas, A. A. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0398-7 · Cited by 29
Predictive power of T-wave alternans and of ventricular gradient hysteresis for the occurrence of ventricular arrhythmias in primary prevention cardioverter-defibrillator patients
Man, S., Winter, P. V. D., Maan, A. C., Thijssen, J., Borleffs, C. J. W., Meerwijk, W. P. M. V., Bootsma, M., van Erven, L., van der Wall, E. E., Schalij, M. J., et al. (2011) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2011.05.004 · Cited by 28
Microvolt T-wave Alternans: Where Are We Now?
Aro, A. L., Kenttä, T. V., & Huikuri, H. V. (2016) · Arrhythmia & Electrophysiology Review · doi:10.15420/aer.2015.28.1 · Cited by 27
Microvolt T-Wave Alternans in End-Stage Renal Disease Patients—Associations with Uremic Cardiomyopathy
Patel, R. K., Mark, P. B., Halliday, C. A., Steedman, T., Dargie, H. J., Cobbe, S. M., & Jardine, A. G. (2010) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.06370710 · Cited by 26
Heart Failure and Sudden Cardiac Death
Saour, B., Smith, B., & Yancy, C. W. (2017) · Cardiac Electrophysiology Clinics · doi:10.1016/j.ccep.2017.07.010 · Cited by 27
Predictive Value of Microvolt T-Wave Alternans for Cardiac Death or Ventricular Tachyarrhythmic Events in Ischemic and Nonischemic Cardiomyopathy Patients: A Meta-Analysis
Calò, L., Santo, T. D., Nuccio, F., Sciarra, L., Luca, L. D., Stefano, L. M. D. S., Piroli, E., Zuccaro, L. M., Rebecchi, M., Ruvo, E. D., et al. (2011) · Annals of Noninvasive Electrocardiology · doi:10.1111/j.1542-474x.2011.00467.x · Cited by 25
Differential multivariable risk prediction of appropriate shock versus competing mortality - A prospective cohort study to estimate benefits from ICD therapy
Bergau, L., Willems, R., Sprenkeler, D. J., Fischer, T. H., Flevari, P. G., Hasenfuss, G. P., Katsaras, D. N., Kirova, A., Lehnart, S. E., Lüthje, L., et al. (2018) · International Journal of Cardiology · doi:10.1016/j.ijcard.2018.06.103 · Cited by 25
Guidelines for Risks and Prevention of Sudden Cardiac Death (JCS 2010) : Digest Version
Aizawa, Y., Horie, M., Inoue, H., Kamakura, S., Katoh, T., Matsuzaki, M., Misaki, T., Mitamura, H., Murakawa, Y., Nitta, T., et al. (2012) · Institutional Repositories DataBase (IRDB) · Cited by 24
Sudden cardiac death: The role of imaging
van der Bijl, P., Delgado, V., & Bax, J. J. (2017) · International Journal of Cardiology · doi:10.1016/j.ijcard.2017.03.010 · Cited by 23
Microvolt T-wave alternans as a predictor of mortality and severe arrhythmias in patients with left-ventricular dysfunction: a systematic review and meta-analysis
van der Avoort, C. J., Filion, K. B., Dendukuri, N., & Brophy, J. M. (2009) · BMC Cardiovascular Disorders · doi:10.1186/1471-2261-9-5 · Cited by 22
Risk factors of self-terminating and perpetuating ventricular tachyarrhythmias in post-infarction patients with moderately depressed left ventricular function, a CARISMA sub-analysis
Perkiömäki, J. S., Thomsen, P. E. B., Kiviniemi, A. M., Messier, M., Huikuri, H. V., & for the CARISMA study investigators (2011) · EP Europace · doi:10.1093/europace/eur166 · Cited by 21
Prognostic utility of T-wave alternans in a real-world population of patients with left ventricular dysfunction: the PREVENT-SCD study
For the PREVENT-SCD Investigators, Shizuta, S., Andò, K., Nobuyoshi, M., Ikeda, T., Yoshino, H., Hiramatsu, S., Kazatani, Y., Yamashiro, K., Okajima, K., et al. (2011) · Clinical Research in Cardiology · doi:10.1007/s00392-011-0368-2 · Cited by 20
Evaluation of Toxicity for Heart Failure Therapeutics
Link, M. G., Yan, G., & Kowey, P. R. (2010) · Circulation Heart Failure · doi:10.1161/circheartfailure.109.917781 · Cited by 20
Relationship Between Early Diastolic Dysfunction and Abnormal Microvolt T-Wave Alternans in Patients With Type 2 Diabetes
Bonapace, S., Targher, G., Molon, G., Rossi, A., Costa, A., Zenari, L., Bertolini, L., Cian, D. M., Lanzoni, L. D. A., & Barbieri, E. (2011) · Circulation Cardiovascular Imaging · doi:10.1161/circimaging.110.962951 · Cited by 19
Improving the appropriateness of sudden arrhythmic death primary prevention by implantable cardioverter-defibrillator therapy in patients with low left ventricular ejection fraction. Point of view
Disertori, M., Gulizia, M. M., Casolo, G., Delise, P., Lenarda, A. D., Tano, G. D., Lunati, M., Mestroni, L., Salerno‐Uriarte, J. A., & Tavazzi, L. (2016) · Journal of Cardiovascular Medicine · doi:10.2459/jcm.0000000000000368 · Cited by 19
Sudden Cardiac Death Risk Stratification in Patients with Heart Failure
Lorvidhaya, P., Addo, K. N., Chodosh, A., Iyer, V., Lum, J. J., & Buxton, A. E. (2011) · Heart Failure Clinics · doi:10.1016/j.hfc.2010.12.001 · Cited by 18
Risk stratification of ventricular arrhythmias in patients with systolic heart failure
Vest, R. N., & Gold, M. R. (2010) · Current Opinion in Cardiology · doi:10.1097/hco.0b013e3283387a73 · Cited by 18
A combined anatomic and electrophysiologic substrate based approach for sudden cardiac death risk stratification
Merchant, F. M., Zheng, H., Bigger, T., Steinman, R. C., Ikeda, T., Pedretti, R. F. E., Salerno‐Uriarte, J. A., Klersy, C., Chan, P. S., Bartone, C. L., et al. (2013) · American Heart Journal · doi:10.1016/j.ahj.2013.06.023 · Cited by 18
Prediction of Appropriate Shocks Using 24-Hour Holter Variables and T-Wave Alternans After First Implantable Cardioverter-Defibrillator Implantation in Patients With Ischemic or Nonischemic Cardiomyopathy
Seegers, J., Bergau, L., Expósito, P. M., Bauer, A., Fischer, T. H., Lüthje, L., Hasenfuss, G. P., Friede, T., & Zabel, M. (2016) · The American Journal of Cardiology · doi:10.1016/j.amjcard.2016.04.016 · Cited by 18
JCS / JHRS 2022 Guideline on Diagnosis and Risk Assessment of Arrhythmia
Takase, B., Ikeda, T., Shimizu, W., Abe, H., Aiba, T., Chinushi, M., Koba, S., KUSANO, K. F., Niwano, S., Takahashi, N., et al. (2024) · Journal of Arrhythmia · doi:10.1002/joa3.13052 · Cited by 19
Microvolt T-wave alternans during exercise and pacing are not comparable
Kraaier, K., Verhorst, P. M. J., van der Palen, J. A. M., van Dessel, P. F. H. M., Wilde, A. A. M., & SCHOLTEN, M. F. (2009) · EP Europace · doi:10.1093/europace/eup253 · Cited by 16
Prognostic value of average T-wave alternans and QT variability for cardiac events in MADIT-II patients
Monasterio, V., Martínez, J. P., Laguna, P., McNitt, S. A., Polonsky, S., Moss, A. J., Haigney, M. C., Zaręba, W., & Couderc, J. (2013) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2013.08.004 · Cited by 15
The clinical value of T-wave alternans derived from Holter monitoring
Lewek, J., Ptaszynski, P. A., Klingenheben, T., & Cygankiewicz, I. (2016) · EP Europace · doi:10.1093/europace/euw292 · Cited by 15
Heart Rate Turbulence and T‐Wave Alternans in Patients with Coronary Artery Disease: The Influence of Diabetes
Perkiömäki, J. S., Exner, D. V., Piira, O.-P., Kavanagh, K. M., Lepojärvi, S., Talajic, M. R., Karvonen, J., Philippon, F., Junttila, J. M., Coutu, B., et al. (2015) · Annals of Noninvasive Electrocardiology · doi:10.1111/anec.12244 · Cited by 13
Quantitative T-wave alternans analysis for guiding medical therapy: An underexploited opportunity
Verrier, R. L., & Malík, M. (2014) · Trends in Cardiovascular Medicine · doi:10.1016/j.tcm.2014.10.006 · Cited by 13
Spectral Microvolt T-Wave Alternans Testing has no Prognostic Value in Patients Recently Hospitalized with Decompensated Heart Failure
Jackson, C. E., Myles, R. C., Tsorlalis, I. K., Dalzell, J. R., Rocchiccioli, P., Rodgers, J. R., Spooner, R. J., Greenlaw, N., Ford, I., Gardner, R. S., et al. (2013) · European Journal of Heart Failure · doi:10.1093/eurjhf/hft085 · Cited by 13
On the estimation of T-wave alternans using the spectral fast fourier transform method
Armoundas, A. A., Mela, T., & Merchant, F. M. (2011) · Heart Rhythm · doi:10.1016/j.hrthm.2011.10.013 · Cited by 13
Is T-Wave Alternans Testing Feasible in Candidates for Prophylactic Implantable Defibrillators?
Kraaier, K., McCracken, T., van der Palen, J. A. M., Wilde, A. A. M., & SCHOLTEN, M. F. (2010) · Netherlands Heart Journal · doi:10.1007/s12471-010-0053-5 · Cited by 13
A translational approach to probe the proarrhythmic potential of cardiac alternans: a reversible overture to arrhythmogenesis?
Merchant, F. M., Sayadi, O., Puppala, D., Moazzami, K., Heller, V., & Armoundas, A. A. (2013) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00639.2013 · Cited by 13
Risk Stratification for Sudden Cardiac Death after Acute Myocardial Infarction
Liew, R., & Chiam, P. T. L. (2010) · Annals of the Academy of Medicine Singapore · doi:10.47102/annals-acadmedsg.v39n3p237 · Cited by 13
Refining Patient Selection for Primary Prevention Implantable Cardioverter-Defibrillator Therapy
Tung, R. H., & Swerdlow, C. D. (2009) · Circulation · doi:10.1161/circulationaha.109.891069 · Cited by 13
Prospective Use of Microvolt T-Wave Alternans Testing to Guide Primary Prevention Implantable Cardioverter Defibrillator Therapy
Merchant, F. M., Salerno‐Uriarte, J. A., Caravati, F., Falcone, S., Molon, G., Marangoni, D., Raczak, G., Daniłowicz‐Szymanowicz, L., Pedretti, R. F. E., Braga, S. S., et al. (2015) · Circulation Journal · doi:10.1253/circj.cj-15-0253 · Cited by 12
The value of the 12-lead electrocardiogram in the prediction of sudden cardiac death
Calò, L., Lanza, O., Crescenzi, C., Parisi, C., Panattoni, G., Martino, A., Rebecchi, M., Tarzia, P., Ciampi, P., Romeo, F., et al. (2023) · European Heart Journal Supplements · doi:10.1093/eurheartjsupp/suad023 · Cited by 12
Risk Stratification and Prevention of Sudden Death in Patients with Heart Failure
Banna, M., & Indik, J. H. (2011) · Current Treatment Options in Cardiovascular Medicine · doi:10.1007/s11936-011-0144-7 · Cited by 12
Role of risk stratification and genetics in sudden cardiac death
Rai, V., & Agrawal, D. K. (2016) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2016-0457 · Cited by 14
Molecular imaging to predict ventricular arrhythmia in heart failure
Wollenweber, T., & Bengel, F. M. (2014) · Journal of Nuclear Cardiology · doi:10.1007/s12350-014-9975-4 · Cited by 11
Post-Ventricular Premature Contraction Phase Correction Improves the Predictive Value of Average T-Wave Alternans in Ambulatory ECG Recordings
Martín-Yebra, A., Monasterio, V., Cygankiewicz, I., de Luna, A. B., Caiani, E. G., Laguna, P., & Martínez, J. P. (2017) · IEEE Transactions on Biomedical Engineering · doi:10.1109/tbme.2017.2711645 · Cited by 11
LifeMap: towards the development of a new technology in sudden cardiac death risk stratification for clinical use
Ng, G. A., Mistry, A. R., Li, X., Schlindwein, F. S., & Nicolson, W. B. (2018) · EP Europace · doi:10.1093/europace/euy080 · Cited by 11
Microvolt T-wave alternans for risk stratification of cardiac events in ischemic cardiomyopathy: A meta-analysis
Chen, Z., Shi, Y., Hou, X., Xu, S., & Zou, J. (2012) · International Journal of Cardiology · doi:10.1016/j.ijcard.2012.05.050 · Cited by 10
A Novel Method for Determining the Phase of T-Wave Alternans
Sayadi, O., Merchant, F. M., Puppala, D., Mela, T., Singh, J. P., Heist, E. K., Owen, C., & Armoundas, A. A. (2013) · Circulation Arrhythmia and Electrophysiology · doi:10.1161/circep.113.000114 · Cited by 10
Microvolt T-Wave Alternans, Peak Oxygen Consumption, and Outcome in Patients with Severely Impaired Left Ventricular Systolic Function
Gorodeski, E. Z., Cantillon, D. J., Goel, S. S., Kaufman, E. S., Martin, D. O., Hsich, E., Blackstone, E. H., & Lauer, M. S. (2009) · The Journal of Heart and Lung Transplantation · doi:10.1016/j.healun.2009.04.009 · Cited by 10
Sudden Cardiac Death Risk Stratification — An Update
Liew, R. (2015) · European Cardiology Review · doi:10.15420/ecr.2015.10.2.118 · Cited by 10
Risk Stratification for Ventricular Tachyarrhythmias by Ambulatory Electrocardiogram-Based Frequency Domain T-Wave Alternans
Kawasaki, M., Yamada, T., Morita, T., Furukawa, Y., Tamaki, S., Iwasaki, Y., Kikuchi, A., Kondo, T., Takahashi, S., Kawai, T., et al. (2015) · Pacing and Clinical Electrophysiology · doi:10.1111/pace.12747 · Cited by 9
Current Attitudes on Cardiac Devices in Heart Failure: A Review
Marangou, J., & Paul, V. (2015) · Clinical Therapeutics · doi:10.1016/j.clinthera.2015.08.012 · Cited by 9
T-Wave Analysis on the 24 h Holter ECG Monitoring as a Predictive Assessment of Major Adverse Cardiovascular Events in Patients with Myocardial Infarction: A Literature Review and Future Perspectives
Duca, Ș.-T., Roca, M., Costache, A. D., Chetran, A., Afrăsânie, I., Miftode, R.-Ş., Tudorancea, I., Matei, I. T., Ciorap, R., Mitu, O., et al. (2023) · Life · doi:10.3390/life13051155 · Cited by 8
Does Microvolt T-Wave Alternans Testing Predict Ventricular Tachyarrhythmias in Patients With Ischemic Cardiomyopathy and Prophylactic Defibrillators? The MASTER (Microvolt T Wave Alternans Testing for Risk Stratification of Post-Myocardial Infarction Patients) Trial
Cheitlin, M. D. (2009) · Yearbook of Cardiology · doi:10.1016/s0145-4145(09)79508-5 · Cited by 8
Microvolt T Wave Alternans: Mechanisms and Implications for Prediction of Sudden Cardiac Death
Rader, F., Wilson, L. D., Costantini, O., & ROSENBAUM, D. S. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4978-1_10 · Cited by 8
The Year in Review of Clinical Cardiac Electrophysiology
Marcus, G. M., Keung, E. C., & Scheinman, M. M. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.09.062 · Cited by 7
Clinical applications of T-wave alternans assessed during exercise stress testing and ambulatory ECG monitoring
Verrier, R. L., & Malík, M. (2013) · Journal of Electrocardiology · doi:10.1016/j.jelectrocard.2013.06.006 · Cited by 7

Authors: Chow, T., Kereiakes, D. J., Onufer, J., Woelfel, A., Gursoy, S., Peterson, B. J., Brown, M. L., Pu, W., & Benditt, D. G.
Affiliations: Christ Hospital (US)
Medtronic (United States) (US)
University of Minnesota (US)
ORCID: Kereiakes, Dean J.
Pu, Wenji
Benditt, David G.
Venue: Journal of the American College of Cardiology
Publisher: Elsevier BV
Published: 2008-11
Volume: 52
Issue: 20
Pages: 1607-1615
ISSN: 0735-1097 (ISSN-L)
DOI: 10.1016/j.jacc.2008.08.018
OpenAlex: W84927980
Cited by: 201
References: 30
Citations by year: 2024: 3 · 2023: 4 · 2022: 6 · 2021: 5 · 2020: 3 · 2019: 3 · 2018: 11 · 2017: 12 · 2016: 10 · 2015: 12 · 2014: 11 · 2013: 21 · 2012: 23
FWCI: 18.68
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 1718 d)
Locations: Journal of the American College of Cardiology (publishedVersion)
PubMed (publishedVersion)
Funders: Medtronic
Topics: Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac pacing and defibrillation studies
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac electrophysiology and arrhythmias
Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Arrhythmias and Treatments
Keywords: microvolt T-wave alternans, ventricular tachyarrhythmia, ischemic cardiomyopathy, implantable cardioverter-defibrillator, MADIT II, myocardial infarction, left ventricular ejection fraction, arrhythmia risk prediction, all-cause mortality
MeSH terms: Aged, Female, Heart Function Tests, Humans, Male, Middle Aged, Cardiomyopathies, Prospective Studies, Defibrillators, Implantable, Tachycardia, Ventricular, Myocardial Ischemia

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Does Microvolt T-Wave Alternans Testing Predict Ventricular Tachyarrhythmias in Patients With Ischemic Cardiomyopathy and Prophylactic Defibrillators?

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks