The DOI matches its Crossref record; 23 of the 23 references it cites were found in a registry or an index.
Usefulness of the Valvuloarterial Impedance to Predict Adverse Outcome in Asymptomatic Aortic Stenosis
Open accessAbstract
OBJECTIVES This study was designed to examine the prognostic value of valvuloarterial impedance (Z(va)) in patients with aortic stenosis (AS). BACKGROUND We previously showed that the Z(va) is superior to standard indexes of AS severity in estimating the global hemodynamic load faced by the left ventricle (LV) and predicting the occurrence of LV dysfunction. This index is calculated by dividing the estimated LV systolic pressure (systolic arterial pressure + mean transvalvular gradient) by the stroke volume indexed for the body surface area. METHODS We retrospectively analyzed the clinical and echocardiographic data of 544 consecutive patients having at least moderate AS (aortic jet velocity > or =2.5 m.s(-1)) and no symptoms at baseline. The primary end point for this study was the overall mortality regardless of the realization of aortic valve replacement (AVR). RESULTS Four-year survival was significantly (p < 0.001) lower in the patients with a baseline Z(va) > or =4.5 mm Hg x ml(-1) x m(2) (65 +/- 5%) compared with those with Z(va) between 3.5 and 4.5 mm Hg x ml(-1) x m(2) (78 +/- 4%) and those with Z(va) < or =3.5 mm Hg x ml(-1) x m(2) (88 +/- 3%). The risk of mortality was increased by 2.76-fold in patients with Z(va) > or =4.5 mm Hg x ml(-1) x m(2) and by 2.30-fold in those with a Z(va) between 3.5 and 4.5 mm Hg x ml(-1) x m(2) after adjusting for other risk factors and type of treatment (surgical vs. medical). CONCLUSIONS Increased Z(va) is a marker of excessive LV hemodynamic load, and a value >3.5 successfully identifies patients with a poor outcome. These findings suggest that beyond standard indexes of stenosis severity, the consideration of Z(va) may be useful to improve risk stratification and clinical decision making in patients with AS.
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Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Circulation · doi:10.1161/circulationaha.106.176857 · Cited by 8,495
Authors/Task Force Members, Vahanian, A., Baumgartner, H., Bax, J., Butchart, E., Dion, R., Filippatos, G., Flachskampf, F., Hall, R., Iung, B., et al. (2006) · European Heart Journal · doi:10.1093/eurheartj/ehl428 · Cited by 3,593
ACC/AHA 2006 Guidelines for the Management of Patients With Valvular Heart Disease
Bonow, R. O., Carabello, B. A., Chatterjee, K., de Leon, A. C., Faxon, D. P., Freed, M. D., Gaasch, W. H., Lytle, B. W., Nishimura, R. A., O’Gara, P. T., et al. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.05.021 · Cited by 1,702
Predictors of Outcome in Severe, Asymptomatic Aortic Stenosis
Rosenhek, R., Binder, T., Porenta, G., Lang, I., Christ, G., Schemper, M., Maurer, G., & Baumgartner, H. (2000) · New England Journal of Medicine · doi:10.1056/nejm200008313430903 · Cited by 1,338
Otto, C. M., Burwash, I. G., Legget, M. E., Munt, B. I., Fujioka, M., Healy, N. L., Kraft, C. D., Miyake-Hull, C. Y., & Schwaegler, R. G. (1997) · Circulation · doi:10.1161/01.cir.95.9.2262 · Cited by 1,146
Freeman, R. V., & Otto, C. M. (2005) · Circulation · doi:10.1161/circulationaha.104.486738 · Cited by 1,006
Hachicha, Z., Dumesnil, J. G., Bogaty, P., & Pibarot, P. (2007) · Circulation · doi:10.1161/circulationaha.106.668681 · Cited by 959
Self-citationPellikka, P. A., Sarano, M. E., Nishimura, R. A., Malouf, J. F., Bailey, K. R., Scott, C. G., Barnes, M. E., & Tajik, A. J. (2005) · Circulation · doi:10.1161/circulationaha.104.495903 · Cited by 864
Prosthetic Heart Valves: Selection of the Optimal Prosthesis and Long-Term Management
Pibarot, P., & Dumesnil, J. G. (2009) · Circulation · doi:10.1161/circulationaha.108.778886 · Cited by 786
Self-citationOtto, C. M. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.03.002 · Cited by 499
Cited by
2025 ESC/EACTS Guidelines for the management of valvular heart disease
Praz, F., Borger, M. A., Lanz, J., Marin-Cuartas, M., Abreu, A., Adamo, M., Ajmone Marsan, N., Barili, F., Bonaros, N., Cosyns, B., et al. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf194 · Cited by 1,072
Dweck, M. R., Boon, N. A., & Newby, D. E. (2012) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2012.02.093 · Cited by 692
The Complex Nature of Discordant Severe Calcified Aortic Valve Disease Grading
Clavel, M.-A., Messika-Zeitoun, D., Pibarot, P., Aggarwal, S. R., Malouf, J., Araoz, P. A., Michelena, H. I., Cueff, C., Larose, E., Capoulade, R., et al. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.08.1621 · Cited by 569
Herrmann, H. C., Pibarot, P., Hueter, I., Gertz, Z. M., Stewart, W. J., Kapadia, S., Tuzcu, E. M., Babaliaros, V., Thourani, V., Szeto, W. Y., et al. (2013) · Circulation · doi:10.1161/circulationaha.112.001290 · Cited by 433
Eleid, M. F., Sorajja, P., Michelena, H. I., Malouf, J. F., Scott, C. G., & Pellikka, P. A. (2013) · Circulation · doi:10.1161/circulationaha.113.003695 · Cited by 324
Metadata
- Authors
- Hachicha, Z., Dumesnil, J. G., & Pibarot, P.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2009-09
- Volume
- 54
- Issue
- 11
- Pages
- 1003-1011
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2037402552
- Cited by
- 356
- References
- 23
- FWCI
- 10.87
- Type
- journal article
- Language
- en
- Open access
- bronze
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