The DOI matches its Crossref record; 115 of the 115 references it cites were found in a registry or an index.
Iron Overload Cardiomyopathy
Open accessAbstract
The prevalence of Iron Overload Cardiomyopathy (IOC) is increasing. The spectrum of symptoms of IOC is varied. Early in the disease process, patients may be asymptomatic while severely overloaded patients can have terminal heart failure complaints that are refractory to treatment. It has been shown that early recognition and intervention may alter outcomes. Biochemical markers and tissue biopsy, that have traditionally been used to diagnose and guide therapy, are not sensitive enough to detect early cardiac iron deposition. Newer diagnostic modalities such as MRI are noninvasive and can assess quantitative cardiac iron load. Phlebotomy and chelating drugs are suboptimal means of treating IOC; hence the roles of gene therapy, hepcidin, and CCBs are being actively investigated. There is a need for the development of clinical guidelines in order to improve the management of this emerging complex disease.
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Cites
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2013 ACCF/AHA Guideline for the Management of Heart Failure
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Yancy, C. W., Jessup, M., Bozkurt, B., Butler, J., Casey, D. E., Drazner, M. H., Fonarow, G. C., Geraci, S. A., Horwich, T., Januzzi, J. L., et al. (2013) · Circulation · doi:10.1161/cir.0b013e31829e8776 · Cited by 2,106
Cardiac T1 Mapping and Extracellular Volume (ECV) in clinical practice: a comprehensive review
Haaf, P., Garg, P., Messroghli, D. R., Broadbent, D. A., Greenwood, J. P., & Plein, S. (2016) · Journal of Cardiovascular Magnetic Resonance · doi:10.1186/s12968-016-0308-4 · Cited by 959
Loss of Cardiac Ferritin H Facilitates Cardiomyopathy via Slc7a11-Mediated Ferroptosis
Fang, X., Cai, Z., Wang, H., Han, D., Cheng, Q., Zhang, P., Gao, F., Yu, Y., Song, Z., Wu, Q., et al. (2020) · Circulation Research · doi:10.1161/circresaha.120.316509 · Cited by 770
A role of PIEZO1 in iron metabolism in mice and humans
Ma, S., Dubin, A. E., Zhang, Y., Mousavi, S. A. R., Wang, Y., Coombs, A. M., Loud, M., Andolfo, I., & Patapoutian, A. (2021) · Cell · doi:10.1016/j.cell.2021.01.024 · Cited by 232
Metadata
- Authors
- Gujja, P., Rosing, D. R., Tripodi, D. J., & Shizukuda, Y.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2010-09
- Volume
- 56
- Issue
- 13
- Pages
- 1001-1012
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W8599571
- Cited by
- 327
- References
- 115
- FWCI
- 7.18
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Gujja, P., Rosing, D. R., Tripodi, D. J., & Shizukuda, Y. (2010). Iron Overload Cardiomyopathy. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2010.03.083
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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