Decline in Functional Performance Predicts Later Increased Mobility Loss and Mortality in Peripheral Arterial Disease
Open accessAbstract
Objectives We hypothesized that a greater 2-year decline in office-based functional performance measures would be associated with greater mobility loss and mortality in people with peripheral arterial disease (PAD).Background Associations of decline in functional performance with clinically important outcomes in patients with PAD are unknown.Methods A total of 440 men and women with PAD completed the 6-min walk test and measures of walking velocity at baseline and annually for 2 years. Participants were categorized into tertiles according to their functional decline between baseline and 2-year follow-up and were followed annually after the functional change assessment. Cox proportional hazard models were used to assess relations between the 2-year change in functional performance with later mortality and mobility loss, with adjustments for age, sex, race, ankle brachial index, comorbidities, and other confounders.Results A total of 102 participants (23.2%) died during a median follow-up of 44.5 months after functional change was assessed. Of 319 participants without baseline mobility disability, 60 (18.8%) developed mobility loss after functional change was assessed. Participants in the tertile with the greatest 6-min walk decline had the highest subsequent mobility loss (hazard ratio [HR]: 3.50; 95% confidence interval [CI]: 1.56 to 7.85; p = 0.002), all-cause mortality (HR: 2.16; 95% CI: 1.28 to 3.64; p = 0.004), and cardiovascular disease mortality (HR: 2.45; 95% CI: 1.08 to 5.54; p = 0.031), compared with those with the smallest 6-min walk decline. Greater declines in fastest-paced 4-m walking velocity were associated with higher mobility loss (p trend = 0.018), all-cause mortality (p trend = 0.01), and cardiovascular mortality (p trend = 0.004).Conclusions Participants with PAD with declining functional performance are at increased risk for later mobility loss and mortality.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Strong evidence from multiple large observational studies indicates that CVD is a risk factor for frailty and that frail patients are more likely to develop CVD than non-frail individuals.
“Strong evidence from multiple, large, observational studies indicates that the presence of CVD is a risk factor for frailty and that patients with frailty are more likely to develop CVD than those who are not frail”
From Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty (2018) · cites this paper as [203]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Guralnik, J. M., Simonsick, E. M., Ferrucci, L., Glynn, R. J., Berkman, L. F., Blazer, D. G., Scherr, P. A., & Wallace, R. B. (1994) · Journal of Gerontology · doi:10.1093/geronj/49.2.m85 · Cited by 9,792 · see citing works
Self-citationAltman, R., Asch, E., Bloch, D., Bole, G., Borenstein, D., Brandt, K., Christy, W., Cooke, T. D., Greenwald, R., Hochberg, M., et al. (1986) · Arthritis & Rheumatism · doi:10.1002/art.1780290816 · Cited by 6,777 · see citing works
Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability
Guralnik, J. M., Ferrucci, L., Simonsick, E. M., Salive, M. E., & Wallace, R. B. (1995) · New England Journal of Medicine · doi:10.1056/nejm199503023320902 · Cited by 4,083 · see citing works
Self-citationAltman, R. D., Alarcón, G. S., Appelrouth, D. J., Bloch, D. A., BORENSTEIN, D. G., Brandt, K. D., Brown, C., Cooke, T. D. V., Daniel, W., Feldman, D. P., et al. (1991) · Arthritis & Rheumatism · doi:10.1002/art.1780340502 · Cited by 2,631 · see citing works
Fowkes, F. G. R., Murray, G. D., Butcher, I., Heald, C. L., Lee, R. J., Chambless, L. E., Folsom, A. R., Hirsch, A. T., Dramaix, M., DeBacker, G., et al. (2008) · JAMA · doi:10.1001/jama.300.2.197 · Cited by 1,870 · see citing works
Self-citationChecking the Cox model with cumulative sums of martingale-based residuals
LIN, D. Y., WEI, L. J., & YING, Z. (1993) · Biometrika · doi:10.1093/biomet/80.3.557 · Cited by 1,432 · see citing works
Disability in Older Adults: Evidence Regarding Significance, Etiology, and Risk
Fried, L. P., & Guralnik, J. M. (1997) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1997.tb00986.x · Cited by 862 · see citing works
Self-citationLeg Symptoms in Peripheral Arterial Disease
McDermott, M. M., Greenland, P., Liu, K., Guralnik, J. M., Criqui, M. H., Dolan, N. C., Chan, C., Celic, L., Pearce, W. H., Schneider, J. R., et al. (2001) · JAMA · doi:10.1001/jama.286.13.1599 · Cited by 856 · see citing works
Self-citationFunctional Decline in Peripheral Arterial Disease
McDermott, M. M., Liu, K., Greenland, P., Guralnik, J. M., Criqui, M. H., Chan, C., Pearce, W. H., Schneider, J. R., Ferrucci, L., Celic, L., et al. (2004) · JAMA · doi:10.1001/jama.292.4.453 · Cited by 641 · see citing works
Self-citationMcDermott, M. M., Greenland, P., Liu, K., Guralnik, J. M., Celic, L., Criqui, M. H., Chan, C., Martin, G. J., Schneider, J., Pearce, W. H., et al. (2002) · Annals of Internal Medicine · doi:10.7326/0003-4819-136-12-200206180-00008 · Cited by 532 · see citing works
Self-citationThe Women's Health and Aging Study: Health and Social Characteristics of Older Women with Disability
Guralnik, J. M., Fried, L. P., Simonsick, E. M., Kasper, J. D., & Lafferty, M. E. (1995) · PsycEXTRA Dataset · doi:10.1037/e306362003-001 · Cited by 504 · see citing works
Self-citationMcDermott, M. M., Ades, P., Guralnik, J. M., Dyer, A., Ferrucci, L., Liu, K., Nelson, M., Lloyd-Jones, D., Van Horn, L., Garside, D., et al. (2009) · JAMA · doi:10.1001/jama.2008.962 · Cited by 449 · see citing works
Self-citationThe Clinical Utility of a Six‐Minute Walk Test in Peripheral Arterial Occlusive Disease Patients
Montgomery, P. S., & Gardner, A. W. (1998) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.1998.tb03804.x · Cited by 391 · see citing works
Subclavian Artery Stenosis: Prevalence, Risk Factors, and Association With Cardiovascular Diseases
Shadman, R., Criqui, M. H., Bundens, W. P., Fronek, A. S., Denenberg, J. O., Gamst, A. C., & McDermott, M. M. (2004) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2004.04.044 · Cited by 382 · see citing works
Self-citationMcDermott, M. M., Criqui, M. H., Liu, K., Guralnik, J. M., Greenland, P., Martin, G. J., & Pearce, W. H. (2000) · Journal of Vascular Surgery · doi:10.1067/mva.2000.108640 · Cited by 277 · see citing works
Self-citationPhysical Activity During Daily Life and Mortality in Patients With Peripheral Arterial Disease
Garg, P. K., Tian, L., Criqui, M. H., Liu, K., Ferrucci, L., Guralnik, J. M., Tan, J. R., & McDermott, M. M. (2006) · Circulation · doi:10.1161/circulationaha.105.605246 · Cited by 256 · see citing works
Self-citationMcDermott, M. M., Hoff, F. L., Ferrucci, L., Pearce, W. H., Guralnik, J. M., Tian, L., Liu, K., Schneider, J. R., Sharma, L., Tan, J. R., et al. (2007) · Journal of the American Geriatrics Society · doi:10.1111/j.1532-5415.2007.01092.x · Cited by 170 · see citing works
Self-citationPrognostic value of functional performance for mortality in patients with peripheral artery disease
McDermott, M. M., Tian, L., Liu, K., Guralnik, J. M., Ferrucci, L., Tan, J., Pearce, W. H., Schneider, J. R., & Criqui, M. H. (2008) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.12.034 · Cited by 169 · see citing works
Self-citationValidation of death certificate diagnosis for coronary heart disease
Coady, S., Sorlie, P. D., Cooper, L. S., Folsom, A. R., Rosamond, W. D., & Conwill, D. E. (2001) · Journal of Clinical Epidemiology · doi:10.1016/s0895-4356(00)00272-9 · Cited by 158 · see citing works
Midlife Physical Activity and Mobility in Older Age
Patel, K. V., Coppin, A. K., Manini, T. M., Lauretani, F., Bandinelli, S., Ferrucci, L., & Guralnik, J. M. (2006) · American Journal of Preventive Medicine · doi:10.1016/j.amepre.2006.05.005 · Cited by 155 · see citing works
Self-citationMcDermott, M. M., Ades, P. A., Dyer, A. R., Guralnik, J. M., Kibbe, M. R., & Criqui, M. H. (2008) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2008.06.050 · Cited by 136 · see citing works
Self-citationMcDermott, M., Guralnik, J., Tian, L., Ferrucci, L., Liu, K., Liao, Y.-H., & Criqui, M. (2007) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2007.05.030 · Cited by 133 · see citing works
Self-citation
Flagged first, then by citations
Cited by
Sorted by citations
Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty
Ferrucci, L., & Fabbri, E. (2018) · Nature Reviews Cardiology · doi:10.1038/s41569-018-0064-2 · Cited by 3,690 · see citing works
Self-citationHome-Based Walking Exercise Intervention in Peripheral Artery Disease
McDermott, M. M., Liu, K., Guralnik, J. M., Criqui, M. H., Spring, B. J., Tian, L., Domanchuk, K. J., Ferrucci, L., Lloyd‐Jones, D. M., Kibbe, M. R., et al. (2013) · JAMA · doi:10.1001/jama.2013.7231 · Cited by 305 · see citing works
Self-citationTreat-Jacobson, D., McDermott, M. M., Bronas, U. G., Campia, U., Collins, T. C., Criqui, M. H., Gardner, A. W., Hiatt, W. R., Regensteiner, J. G., Rich, K., et al. (2019) · Circulation · doi:10.1161/cir.0000000000000623 · Cited by 302 · see citing works
Self-citationClinical relevance of sarcopenia in chronic kidney disease
Moorthi, R. N., & Avin, K. G. (2017) · Current Opinion in Nephrology & Hypertension · doi:10.1097/mnh.0000000000000318 · Cited by 272 · see citing works
Update on the pathophysiology and medical treatment of peripheral artery disease
Golledge, J. (2022) · Nature Reviews Cardiology · doi:10.1038/s41569-021-00663-9 · Cited by 240 · see citing works
McDermott, M. M., Guralnik, J. M., Criqui, M. H., Liu, K., Kibbe, M. R., & Ferrucci, L. (2014) · Circulation · doi:10.1161/circulationaha.114.007002 · Cited by 220 · see citing works
Self-citationPathophysiology of Intermittent Claudication in Peripheral Artery Disease.
Hamburg, N., & Creager, M. (2017) · Circulation Journal · doi:10.1253/circj.cj-16-1286 · Cited by 185 · see citing works
Decline in Fast Gait Speed as a Predictor of Disability in Older Adults
Artaud, F., Singh‐Manoux, A., Dugravot, A., Tzourio, C., & Elbaz, A. (2015) · Journal of the American Geriatrics Society · doi:10.1111/jgs.13442 · Cited by 157 · see citing works
Leeper, N. J., MYERS, J. N., Zhou, M. J., Nead, K. T., Syed, A., Kojima, Y., Caceres, R. D., & Cooke, J. P. (2012) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2012.07.051 · Cited by 125 · see citing works
RYAN, T. E., Yamaguchi, D. J., Schmidt, C. A., Zeczycki, T. N., Shaikh, S. R., Brophy, P. M., Green, T. D., Tarpey, M. D., Karnekar, R. R., Goldberg, E. J., et al. (2018) · JCI Insight · doi:10.1172/jci.insight.123235 · Cited by 96 · see citing works
Peripheral artery disease. Part 1: clinical evaluation and noninvasive diagnosis
Lau, J. F., Weinberg, M. D., & Olin, J. W. (2011) · Nature Reviews Cardiology · doi:10.1038/nrcardio.2011.66 · Cited by 93 · see citing works
Mechanisms of retina regeneration in urodeles
Mitashov, V. I. (1996) · The International Journal of Developmental Biology · doi:10.1387/ijdb.8877458 · Cited by 84 · see citing works
Morris, D., Rodríguez, A. J., Moxon, J. V., Cunningham, M. A., McDermott, M. M., MYERS, J. N., Leeper, N. J., Jones, R. E., & Golledge, J. (2014) · Journal of the American Heart Association · doi:10.1161/jaha.114.001105 · Cited by 70 · see citing works
Self-citationCunningham, M. A., Swanson, V., O'Caroll, R. E., & Holdsworth, R. J. (2011) · British journal of surgery · doi:10.1002/bjs.7714 · Cited by 66 · see citing works
Functional Impairment in Peripheral Artery Disease and How to Improve It in 2013
McDermott, M. (2013) · Current Cardiology Reports · doi:10.1007/s11886-013-0347-5 · Cited by 62 · see citing works
Self-citationHeart Failure Risk Across the Spectrum of Ankle-Brachial Index
Gupta, D. K., Skali, H., Claggett, B. L., Kasabov, R., Cheng, S. C., Shah, A. M., Loehr, L. R., HEISS, G. M., Nambi, V., Aguilar, D. A., et al. (2014) · JACC Heart Failure · doi:10.1016/j.jchf.2014.05.008 · Cited by 64 · see citing works
Meaningful change in 6-minute walk in people with peripheral artery disease
McDermott, M. M., Tian, L., Criqui, M. H., Ferrucci, L., Conte, M. S., Zhao, L., Li, L., Sufit, R. L., Polonsky, T. S., Kibbe, M. R., et al. (2020) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2020.03.052 · Cited by 59 · see citing works
Self-citationRYAN, T. E., Schmidt, C. A., Green, T. D., Spangenburg, E. E., Neufer, P. D., & McClung, J. M. (2016) · Diabetes · doi:10.2337/db16-0387 · Cited by 55 · see citing works
Kim, K., Anderson, E. M., Scali, S. T., & RYAN, T. E. (2020) · Antioxidants · doi:10.3390/antiox9121304 · Cited by 51 · see citing works
Jain, A., Liu, K., Ferrucci, L., Criqui, M. H., Tian, L., Guralnik, J. M., Tao, H., & McDermott, M. M. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.01.060 · Cited by 49 · see citing works
Self-citationCommunity walking programs for treatment of peripheral artery disease
Mays, R. J., Rogers, R. K., Hiatt, W. R., & Regensteiner, J. G. (2013) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2013.08.034 · Cited by 48 · see citing works
Przybyłowski, T., Tomalak, W., Siergiejko, Z., Jastrzębski, D., Maskey‐Warzęchowska, M., Piorunek, T., Wojda, E., & Boros, P. W. (2015) · Advances in respiratory medicine · doi:10.5603/piap.2015.0048 · Cited by 47 · see citing works
Exercise therapy for chronic symptomatic peripheral artery disease
Mazzolai, L., Belch, J. J. F., Venermo, M. A., Aboyans, V., Brodmann, M., Bura-Rivière, A., Debus, S., Espinola–Klein, C., Harwood, A. E., Hawley, J. A., et al. (2023) · European Heart Journal · doi:10.1093/eurheartj/ehad734 · Cited by 46 · see citing works
Berru, F. N., Gray, S. E., Thome, T., Kumar, R. A., Salyers, Z. R., Coleman, M. D., Le, D., O’Malley, K. A., Ferreira, L. F., Berceli, S. A., et al. (2019) · Scientific Reports · doi:10.1038/s41598-019-52107-7 · Cited by 44 · see citing works
Luck, J. C., Miller, A. J., Aziz, F., Radtka, J. F., Proctor, D. N., Leuenberger, U. A., Sinoway, L. I., & Muller, M. D. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.01110.2016 · Cited by 43 · see citing works
Durability of Benefits From Supervised Treadmill Exercise in People With Peripheral Artery Disease
McDermott, M. M., Kibbe, M. R., Guralnik, J. M., Ferrucci, L., Criqui, M. H., Domanchuk, K. J., Tian, L., Zhao, L., Li, L., Patel, K., et al. (2018) · Journal of the American Heart Association · doi:10.1161/jaha.118.009380 · Cited by 42 · see citing works
Self-citationGohil, R., Mockford, K., Mazari, F. A. K., Khan, J., Vanicek, N., Chetter, I. C., & Coughlin, P. A. (2012) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2012.05.005 · Cited by 41 · see citing works
Walking Speed, Risk Factors, and Cardiovascular Events in Older Adults—Systematic Review
Alves, D. J. F., Neto, J. B., Júnior, E. R., Zarricueta, B. S. R., Nóbrega, O. D. T., & Córdova, C. (2017) · The Journal of Strength and Conditioning Research · doi:10.1519/jsc.0000000000002182 · Cited by 41 · see citing works
Owens, C. D., Mukli, P., Csípő, T., Lipécz, Á., Silva-Palacios, F., Dasari, T. W., Tarantini, S., Gardner, A. W., Montgomery, P. S., Waldstein, S. R., et al. (2022) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00616.2021 · Cited by 40 · see citing works
McDermott, M. M., Polonsky, T. S., Kibbe, M. R., Tian, L., Zhao, L., Pearce, W. H., Gao, Y., & Guralnik, J. M. (2017) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2017.02.037 · Cited by 36 · see citing works
Self-citationBalestrieri, N. P., Palzkill, V. R., Pass, C. G., Tan, J., Salyers, Z. R., Moparthy, C., Murillo, A., Kim, K., Thome, T., Yang, Q., et al. (2023) · Circulation Research · doi:10.1161/circresaha.123.322875 · Cited by 35 · see citing works
Hotta, K., Batchelor, W., Graven, J., Dahya, V., Noel, T. E., Ghai, A., Katopodis, J., Dixon, W. C., Andrews, R., Pragle, A. S., et al. (2019) · Cardiovascular revascularization medicine · doi:10.1016/j.carrev.2019.05.003 · Cited by 35 · see citing works
Figueiredo, P. H. S., Veloso, L. R. D. S., Lima, M. M. O., Vieira, C. F. D., Alves, F. L., Lacerda, A. C. R., Lima, V. P., Rodrigues, V. G. B., Maciel, E. H. B., & Costa, H. S. (2021) · Journal of Bodywork and Movement Therapies · doi:10.1016/j.jbmt.2021.02.020 · Cited by 34 · see citing works
Lamberti, N., López‐Soto, P. J., Guerzoni, F., Napoli, N., Gasbarro, V., Zamboni, P., Tsolaki, E., Taddia, M. C., Rodríguez‐Borrego, M. A., Manfredini, R., et al. (2019) · Internal and Emergency Medicine · doi:10.1007/s11739-019-02176-3 · Cited by 33 · see citing works
Mitochondrial Regulation of the Muscle Microenvironment in Critical Limb Ischemia
RYAN, T. E., Schmidt, C. A., Green, T. D., Brown, D. A., Neufer, P. D., & McClung, J. M. (2015) · Frontiers in Physiology · doi:10.3389/fphys.2015.00336 · Cited by 32 · see citing works
Single-Nuclei RNA-Sequencing of the Gastrocnemius Muscle in Peripheral Artery Disease
Pass, C. G., Palzkill, V. R., Tan, J., Kim, K., Thome, T., Yang, Q., Fazzone, B. J., Robinson, S. T., O’Malley, K. A., Yue, F., et al. (2023) · Circulation Research · doi:10.1161/circresaha.123.323161 · Cited by 31 · see citing works
Chang, P., Nead, K. T., Olin, J. W., MYERS, J. N., Cooke, J. P., & Leeper, N. J. (2015) · Mayo Clinic Proceedings · doi:10.1016/j.mayocp.2014.12.016 · Cited by 30 · see citing works
Kim, M., Kim, Y., Ryu, G. W., & Choi, M. (2021) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph182010941 · Cited by 30 · see citing works
Gernigon, M., Faucheur, A. L., Noury-Desvaux, B., Mahé, G., & Abraham, P. (2014) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2014.04.053 · Cited by 29 · see citing works
Fernandes, A. A., Britto, R. R., Soares, D. C. M., Velloso, M., & Pereira, D. A. G. (2017) · Brazilian Journal of Physical Therapy · doi:10.1016/j.bjpt.2017.06.001 · Cited by 27 · see citing works
Validity and reliability of 2-min step test in patients with symptomatic peripheral artery disease
Braghieri, H. A., Kanegusuku, H., Corso, S. D., Cucato, G. G., Monteiro, F., Wolosker, N., Correia, M. D. A., & Ritti‐Dias, R. M. (2021) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2021.02.004 · Cited by 28 · see citing works
Correia, M. D. A., da Silva, G. O., Longano, P., Trombetta, I. C., Consolim‐Colombo, F. M., Puech‐Leão, P., Wolosker, N., Cucato, G. G., & Ritti‐Dias, R. M. (2020) · Annals of Physical and Rehabilitation Medicine · doi:10.1016/j.rehab.2020.01.006 · Cited by 25 · see citing works
Fritschi, C., Collins, E. G., O'Connell, S. M., McBurney, C., Butler, J., & Edwards, L. C. (2013) · The Journal of Cardiovascular Nursing · doi:10.1097/jcn.0b013e31824af587 · Cited by 25 · see citing works
Stenholm, S., Guralnik, J. M., Bandinelli, S., & Ferrucci, L. (2013) · The Journals of Gerontology Series A · doi:10.1093/gerona/glt175 · Cited by 24 · see citing works
Self-citationUnique Metabolomic Profile of Skeletal Muscle in Chronic Limb Threatening Ischemia
Khattri, R. B., Kim, K., Thome, T., Salyers, Z. R., O’Malley, K. A., Berceli, S. A., Scali, S. T., & RYAN, T. E. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10030548 · Cited by 24 · see citing works
Maggio, M., Cattabiani, C., Lauretani, F., Artoni, A., Bandinelli, S., Schiavi, G., Vignali, A., Volpi, R., Ceresini, G., Lippi, G., et al. (2012) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2012.09.014 · Cited by 24 · see citing works
Self-citationHeat therapy improves soleus muscle force in a model of ischemia-induced muscle damage
Kim, K., Reid, B. A., Ro, B., Casey, C. A., Song, Q., Kuang, S., & Roseguini, B. T. (2019) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00115.2019 · Cited by 23 · see citing works
Functional Outcomes following Revascularisation for Critical Limb Ischaemia
Rollins, K. E., & Coughlin, P. A. (2012) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2012.01.015 · Cited by 22 · see citing works
Domanchuk, K. J., Ferrucci, L., Guralnik, J. M., Criqui, M. H., Tian, L., Liu, K., Losordo, D. W., Stein, J. H., Green, D., Kibbe, M. R., et al. (2013) · Contemporary Clinical Trials · doi:10.1016/j.cct.2013.09.011 · Cited by 22 · see citing works
Self-citationManfredini, F., Lamberti, N., Guerzoni, F., Napoli, N., Gasbarro, V., Zamboni, P., Mascoli, F., Manfredini, R., Basaglia, N., Rodríguez‐Borrego, M. A., et al. (2019) · Journal of Clinical Medicine · doi:10.3390/jcm8020210 · Cited by 22 · see citing works
IGF-1 Therapy Improves Muscle Size and Function in Experimental Peripheral Arterial Disease
Dong, G., Moparthy, C., Thome, T., Kim, K., Feng, Y., & RYAN, T. E. (2023) · JACC Basic to Translational Science · doi:10.1016/j.jacbts.2022.12.006 · Cited by 21 · see citing works
Roseguini, B. T., Hirai, D. M., Alencar, M. C. N., Ramos, R. P., Silva, B. M., Wolosker, N., Neder, J. A., & Nery, L. E. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00183.2014 · Cited by 21 · see citing works
Senthong, V., Wu, Y., Hazen, S. L., & Tang, W. H. W. (2016) · American Heart Journal · doi:10.1016/j.ahj.2016.10.009 · Cited by 20 · see citing works
Gross, D. A., Cheng, H. S., Zhuang, R., McCoy, M. G., Pérez‐Cremades, D., Salyers, Z. R., Wara, A. K., Haemmig, S., RYAN, T. E., & Feinberg, M. W. (2021) · JCI Insight · doi:10.1172/jci.insight.150761 · Cited by 20 · see citing works
Hammad, T. A., Smolderen, K. G. E., Spertus, J. A., Jones, P. G., & Shishehbor, M. H. (2018) · Vascular Medicine · doi:10.1177/1358863x18785026 · Cited by 20 · see citing works
Ahmed, T., French, S. D., Bélanger, E., Guerra, R. O., Zunzunegui, M. V., & Auais, M. A. (2019) · Journal of the American Medical Directors Association · doi:10.1016/j.jamda.2019.04.014 · Cited by 19 · see citing works
Severity of Coronary Artery Disease Affects Prognosis of Patients With Peripheral Artery Disease
Ishihara, T., Iida, O., Tosaka, A., Soga, Y., Sakamoto, Y., Hirano, K., Nanto, S., & Uematsu, M. (2012) · Angiology · doi:10.1177/0003319712452627 · Cited by 19 · see citing works
Figueiredo, P. H. S., da Silva, A. C. R., Costa, H. S., Nominato, G. A., Lopes, P. H., Campos, P. C., Santos, L. M. D. M., de Alcântara, M. A., Alves, F. L., Rodrigues, V. G. B., et al. (2020) · Disability and Rehabilitation · doi:10.1080/09638288.2020.1812121 · Cited by 18 · see citing works
Farah, B. Q., dos Santos, M. F. L., Cucato, G. G., Kanegusuku, H., Sampaio, L. M. M., Monteiro, F., Wolosker, N., Puech‐Leão, P., Correia, M. D. A., & Ritti‐Dias, R. M. (2021) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2021.07.001 · Cited by 18 · see citing works
Ney, B., Lanzi, S., Calanca, L., & Mazzolai, L. (2021) · Journal of Clinical Medicine · doi:10.3390/jcm10102057 · Cited by 18 · see citing works
de Müllenheim, P., Chaudru, S., Mahé, G., Prioux, J., & Faucheur, A. L. (2015) · Scandinavian Journal of Medicine and Science in Sports · doi:10.1111/sms.12512 · Cited by 18 · see citing works
Arya, S., Khakharia, A., Rothenberg, K. A., Johnson, T. M., Sawyer, P., Kennedy, R., Brown, C. J., & Bowling, C. B. (2020) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2019.08.276 · Cited by 16 · see citing works
Smolderen, K. G. E., van Zitteren, M., Jones, P. G., Spertus, J. A., Heyligers, J. M. M., Nooren, M. J., Vriens, P. W. H. E., & Denollet, J. (2015) · Journal of the American Heart Association · doi:10.1161/jaha.115.001823 · Cited by 16 · see citing works
Interventional‐ and amputation‐stage muscle proteomes in the chronically threatened ischemic limb
RYAN, T. E., Kim, K., Scali, S. T., Berceli, S. A., Thome, T., Salyers, Z. R., O’Malley, K. A., Green, T. D., Karnekar, R. R., Fisher‐Wellman, K. H., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.658 · Cited by 15 · see citing works
Saini, S. K., Pérez‐Cremades, D., Cheng, H. S., Kosmac, K., Peterson, C. A., Li, L., Tian, L., Dong, G., Wu, K. K., Bouverat, B., et al. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.121.023085 · Cited by 14 · see citing works
Self-citationGoldberg, E. J., Schmidt, C. A., Green, T. D., Karnekar, R., Yamaguchi, D. J., Spangenberg, E. E., & McClung, J. (2019) · Frontiers in Physiology · doi:10.3389/fphys.2019.00804 · Cited by 12 · see citing works
Mazzolai, L., Belch, J. J. F., Venermo, M. A., Aboyans, V., Brodmann, M., Bura-Rivière, A., Debus, S., Espinola–Klein, C., Harwood, A. E., Hawley, J. A., et al. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.01.009 · Cited by 17 · see citing works
Stefano, F. A. D., Rios, L. H. P., Fiani, B., Fareed, J., & Tafur, A. J. (2021) · Clinical and Applied Thrombosis/Hemostasis · doi:10.1177/10760296211025625 · Cited by 13 · see citing works
Exercise therapy for chronic symptomatic peripheral artery disease
Mazzolai, L., Belch, J. J. F., Venermo, M. A., Aboyans, V., Brodmann, M., Bura-Rivière, A., Debus, S., Espinola–Klein, C., Harwood, A. E., Hawley, J. A., et al. (2024) · VASA · doi:10.1024/0301-1526/a001112 · Cited by 13 · see citing works
Lanzi, S., Pousaz, A., Calanca, L., & Mazzolai, L. (2022) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2022.12.029 · Cited by 13 · see citing works
Multiomic Analysis of Calf Muscle in Peripheral Artery Disease and Chronic Kidney Disease
Kim, K., Thome, T., Pass, C. G., Stone, L. E., Vugman, N. A., Palzkill, V. R., Yang, Q., O’Malley, K. A., Anderson, E. M., Fazzone, B. J., et al. (2025) · Circulation Research · doi:10.1161/circresaha.124.325642 · Cited by 12 · see citing works
Salyers, Z. R., Coleman, M. D., Le, D., & RYAN, T. E. (2022) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00121.2022 · Cited by 12 · see citing works
Cummings, S. R., Lui, L., Glynn, N. W., Mau, T., Cawthon, P. M., Kritchevsky, S. B., Coen, P. M., Goodpaster, B., Marcinek, D. J., Hepple, R. T., et al. (2024) · Journal of the American Geriatrics Society · doi:10.1111/jgs.18763 · Cited by 12 · see citing works
Zhao, M., Wang, Y., Wang, S., Yang, Y., Li, M., & Wang, K. (2022) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph19063543 · Cited by 11 · see citing works
Gernigon, M., Faucheur, A. L., Fradin, D., Noury-Desvaux, B., Landron, C., Mahé, G., & Abraham, P. (2015) · Medicine · doi:10.1097/md.0000000000000838 · Cited by 11 · see citing works
Lane, R., Mazari, F. A. K., Mockford, K., Vanicek, N., Chetter, I. C., & Coughlin, P. A. (2014) · Vascular and Endovascular Surgery · doi:10.1177/1538574413519711 · Cited by 11 · see citing works
Parkington, T., Broom, D. R., Maden‐Wilkinson, T., Nawaz, S., & Klonizakis, M. (2023) · Vascular Medicine · doi:10.1177/1358863x231200250 · Cited by 11 · see citing works
Hammond, M. M., Tian, L., Zhao, L., Zhang, D., & McDermott, M. M. (2022) · Journal of the American Heart Association · doi:10.1161/jaha.122.026136 · Cited by 10 · see citing works
Self-citationBunte, M. C., House, J. A., Spertus, J. A., Cohen, D. J., Marso, S. P., & Safley, D. M. (2016) · Catheterization and Cardiovascular Interventions · doi:10.1002/ccd.26442 · Cited by 10 · see citing works
Germano-Soares, A. H., Tassitano, R. M., Farah, B. Q., Andrade-Lima, A., Correia, M. D. A., Gába, A., Štefelová, N., Puech‐Leão, P., Wolosker, N., Cucato, G. G., et al. (2021) · Journal of Physical Activity and Health · doi:10.1123/jpah.2020-0487 · Cited by 8 · see citing works
Decision making in the frail vascular surgery patient: A scoping review
Fereydooni, A., Johnson, C. E., Brooke, B. S., & Arya, S. (2024) · Seminars in Vascular Surgery · doi:10.1053/j.semvascsurg.2024.04.003 · Cited by 8 · see citing works
Miceli, M., Baldi, D., Cavaliere, C., Soricelli, A., Salvatore, M., & Claudio Napoli, A. (2019) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2019.1635012 · Cited by 8 · see citing works
Joshi, G., Zhang, S. M., Wang, K., Khoury, R. E., Cataneo, J. L., Jacobs, C. E., White, J. V., & Schwartz, L. B. (2022) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2022.04.052 · Cited by 8 · see citing works
Huang, D., Ma, Z., Wang, J., Li, Y., Zhang, Y., Lin, H., Zhu, X., Xiao, Y., & Zhang, X. (2025) · Biomaterials · doi:10.1016/j.biomaterials.2025.123162 · Cited by 6 · see citing works
Zhang, Y., Zhang, Y., Zhong, C., Wang, Y., Wei, W., & Wu, G. (2024) · Scientific Reports · doi:10.1038/s41598-024-82485-6 · Cited by 6 · see citing works
Addison, O. R., Ryan, A. S., Prior, S. J., Katzel, L. I., Kundi, R., Lal, B. K., & Gardner, A. W. (2016) · Journal of Geriatric Physical Therapy · doi:10.1519/jpt.0000000000000096 · Cited by 6 · see citing works
Hammond, M. M., Tian, L., Zhao, L., Zhang, D., & McDermott, M. M. (2021) · Journal of the American Heart Association · doi:10.1161/jaha.121.021917 · Cited by 6 · see citing works
Self-citationda Silva, G. O., Braghieri, H. A., Oliveira, M. D., Farah, B. Q., Kanegusuku, H., Cucato, G. G., Correia, M. D. A., & Ritti‐Dias, R. M. (2023) · Expert Review of Cardiovascular Therapy · doi:10.1080/14779072.2023.2277355 · Cited by 4 · see citing works
Implementation of supervised exercise therapy in a veteran population with symptomatic claudication
Altin, S. E., Schneider, M. D., Parise, H., Banerjee, S., Wu, W., Meadows, J. L., Pfau, S. E., Keefe, H., & Armstrong, E. J. (2022) · Vascular Medicine · doi:10.1177/1358863x211073622 · Cited by 4 · see citing works
Rodríguez‐Mañas, L., Bouzón, C. A., & Rodríguez, M. C. (2017) · doi:10.1002/9781118954621.ch6 · Cited by 4 · see citing works
La creciente importancia del rendimiento físico en la valoración geriátrica integral
Sánchez, E., Formiga, F., & Cruz-Jentoft, A. J. (2018) · Revista Española de Geriatría y Gerontología · doi:10.1016/j.regg.2018.06.002 · Cited by 3 · see citing works
Peñín‐Grandes, S., Santos‐Lozano, A., Pinto-Fraga, J., Gómez, M. D. L. F., Solá, M. L. D. R., & Martín-Hernández, J. (2021) · Annals of Vascular Surgery · doi:10.1016/j.avsg.2021.07.038 · Cited by 3 · see citing works
Porras, C. P., Teraa, M., Damen, J. A., Hazenberg, C. E. V. B., Bots, M. L., Verhaar, M. C., & Vernooij, R. W. M. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2024.05.029 · Cited by 3 · see citing works
Terada, T., Hausen, M., Mir, H. R., Reed, J. L., & Coutinho, T. A. (2024) · CJC Open · doi:10.1016/j.cjco.2024.09.017 · Cited by 2 · see citing works
Soerensen, U. M., Pedersen, P. U., & Uhrenfeldt, L. (2014) · The JBI Database of Systematic Reviews and Implementation Reports · doi:10.11124/jbisrir-2014-1594 · Cited by 2 · see citing works
Baloch, Z. Q., Abbas, S. A., Prasad, R. M., Raza, S. A., Al-Abcha, A. K., Marone, L., & Ali, A. S. (2021) · Angiology · doi:10.1177/00033197211052125 · Cited by 2 · see citing works
Longitudinal outcomes following peripheral vascular intervention among older persons living with HIV
Kentoffio, K., Sun, T., Xu, J., Parikh, R. V., Hsue, P. Y., & Secemsky, E. A. (2023) · Vascular Medicine · doi:10.1177/1358863x231191822 · Cited by 2 · see citing works
Wang, X., Yang, Y., Zhang, J., & Zang, S. (2023) · BMJ Open · doi:10.1136/bmjopen-2022-069437 · Cited by 2 · see citing works
Pires, M. C. D. O., Alencar, M. A., Makluf, A. S. D., Rezende, T. G., & Pereira, D. A. G. (2024) · Journal of Vascular Nursing · doi:10.1016/j.jvn.2024.09.001 · Cited by 1 · see citing works
Remote Self‐Report Assessment of Walking Impairment in Peripheral Artery Disease
Thanigaimani, S., Deren, A., Burton, N. W., Parmenter, B. J., Alahakoon, C., Golledge, J., Walsh, J., Quigley, F., Norman, P., Jones, R., et al. (2026) · Journal of the American Heart Association · doi:10.1161/jaha.125.046066 · Cited by 1 · see citing works
- Authors
- McDermott, M. M., Liu, K., Ferrucci, L., Tian, L., Guralnik, J. M., Liao, Y., & Criqui, M. H.
- Affiliations
- Northwestern University (US)
- National Institute on Aging (US)
- University of California San Diego (US)
- Corresponding author
- McDermott, Mary M.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2011-02
- Volume
- 57
- Issue
- 8
- Pages
- 962-970
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC3222682
- OpenAlex
- W2156171476
- Cited by
- 122
- References
- 22
- Citations by year
- 2026: 2 · 2025: 5 · 2024: 11 · 2023: 10 · 2022: 14 · 2021: 13 · 2020: 5 · 2019: 10 · 2018: 6 · 2017: 7 · 2016: 5 · 2015: 7 · 2014: 8 · 2013: 9 · 2012: 6
- FWCI
- 8.44
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Heart, Lung, and Blood Institute (R01HL071223, R01HL064739, R01HL076298, R01HL058099)
- Topics
- Health Sciences › Medicine › Surgery › Peripheral Artery Disease Management
- Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
- Health Sciences › Medicine › Geriatrics and Gerontology › Frailty in Older Adults
- Keywords
- peripheral arterial disease, mobility loss, all-cause mortality, cardiovascular mortality, 6-minute walk test, walking speed, functional decline prediction, prognosis
- MeSH terms
- Age Factors, Aged, Cause of Death, Disability Evaluation, Exercise Test, Female, Follow-Up Studies, Humans, Male, Middle Aged, Predictive Value of Tests, Severity of Illness Index, Sex Factors, Time Factors, Cohort Studies, Survival Rate, Proportional Hazards Models, Walking, Exercise Tolerance, Disease Progression, Mobility Limitation, Ankle Brachial Index, Peripheral Arterial Disease
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review