The DOI matches its Crossref record; 68 of the 68 references it cites were found in a registry or an index.
Diabetes Mellitus-Associated Vascular Impairment
Open accessAbstract
It is widely accepted that diabetes mellitus (DM) impairs endothelial nitric oxide synthase activity as well as enhances the production of reactive oxygen species, thus resulting in diminished nitric oxide bioavailability and the consequent pro-atherogenetic alterations. Important biomarkers of the vasculature are related to endothelial dysfunction, to inflammatory and coagulation processes, and to oxidative stress in DM. Several therapeutic strategies might exert favorable effects on the vasculature of diabetic patients, such as insulin analogues, antihypertensive agents, statins, and hypoglycemic agents, whereas in spite of the prominent role of oxidative stress in diabetes, antioxidant therapy remains controversial. The use of specific biomarkers related to vascular function could be a useful therapeutic approach in such patients.
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Cites
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“A single-blind study recently enrolled patients with T2D and examined the variance of certain circulating markers after 15 days of antioxidants.”
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Cited by
Oxidative Stress in Type 2 Diabetes: Impacts from Pathogenesis to Lifestyle Modifications
Caturano, A., D’Angelo, M., Mormone, A., Russo, V., Mollica, M. P., Salvatore, T., Galiero, R., Rinaldi, L., Vetrano, E., Marfella, R., et al. (2023) · Current Issues in Molecular Biology · doi:10.3390/cimb45080420 · Cited by 579
The Function of Rho-Associated Kinases ROCK1 and ROCK2 in the Pathogenesis of Cardiovascular Disease
Hartmann, S., Ridley, A. J., & Lutz, S. (2015) · Frontiers in Pharmacology · doi:10.3389/fphar.2015.00276 · Cited by 355
The Role of Nrf2 in Cardiovascular Function and Disease
Satta, S., Mahmoud, A. M., Wilkinson, F. L., Yvonne Alexander, M., & White, S. J. (2017) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2017/9237263 · Cited by 293
Mitochondria and cardiovascular diseases-from pathophysiology to treatment
Siasos, G., Tsigkou, V., Kosmopoulos, M., Theodosiadis, D., Simantiris, S., Tagkou, N. M., Tsimpiktsioglou, A., Stampouloglou, P. K., Oikonomou, E., Mourouzis, K., et al. (2018) · Annals of Translational Medicine · doi:10.21037/atm.2018.06.21 · Cited by 245
Self-citationJanelidze, S., Hertze, J., Nägga, K., Nilsson, K., Nilsson, C., Wennström, M., van Westen, D., Blennow, K., Zetterberg, H., & Hansson, O. (2017) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2016.11.017 · Cited by 237
Metadata
- Authors
- Tousoulis, D., Papageorgiou, N., Androulakis, E., Siasos, G., Latsios, G., Tentolouris, K., & Stefanadis, C.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2013-08
- Volume
- 62
- Issue
- 8
- Pages
- 667-676
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W23894640
- Cited by
- 264
- References
- 68
- FWCI
- 19.38
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Tousoulis, D., Papageorgiou, N., Androulakis, E., Siasos, G., Latsios, G., Tentolouris, K., & Stefanadis, C. (2013). Diabetes Mellitus-Associated Vascular Impairment. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2013.03.089
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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