The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Lone Atrial Fibrillation
Open accessAbstract
The historical origin of the term ‘lone atrial fibrillation (AF)’ predates by 80 years our current understanding of the pathophysiology of AF, the multitude of known etiologies for AF, and our ability to image and diagnose heart disease. The term was meant to indicate AF in whom subsequent investigations could not demonstrate heart disease, but for many practitioners has become synonymous with ‘idiopathic AF’. As the list of heart diseases has expanded and diagnostic techniques have improved, the prevalence of ‘lone AF’ has fallen. The legacy of the intervening years is that definitions of ‘lone AF’ in the literature are inconsistent such that studies of ‘lone AF’ are not comparable Guidelines provide a vague definition of ‘lone AF’ but do not provide direction about how much or what kind of imaging and other testing are necessary to exclude heart disease. There has been an explosion in the understanding of the pathophysiology of AF in the last 20 years in particular. Nevertheless, there are no apparently unique mechanisms for AF in patients categorized as ‘lone AF’. In addition, the term ‘lone AF’ is not invariably useful in making treatment decisions, and other tools for doing so have been more thoroughly and carefully validated. It is therefore recommended that use of the term ‘lone AF’ be avoided.
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Citations
Cites
Worldwide Epidemiology of Atrial Fibrillation: A Global Burden of Disease 2010 Study
Chugh, S. S., Havmoeller, R., Narayanan, K., Singh, D., Rienstra, M., Benjamin, E. J., Gillum, R. F., Kim, Y.-H., McAnulty, J. H., Zheng, Z.-J., et al. (2014) · Circulation · doi:10.1161/circulationaha.113.005119 · Cited by 4,506
Self-citationMiyasaka, Y., Barnes, M. E., Gersh, B. J., Cha, S. S., Bailey, K. R., Abhayaratna, W. P., Seward, J. B., & Tsang, T. S. M. (2006) · Circulation · doi:10.1161/circulationaha.105.595140 · Cited by 2,564
Wang, T. J., Larson, M. G., Levy, D., Vasan, R. S., Leip, E. P., Wolf, P. A., D’Agostino, R. B., Murabito, J. M., Kannel, W. B., & Benjamin, E. J. (2003) · Circulation · doi:10.1161/01.cir.0000072767.89944.6e · Cited by 1,970
Calkins, H., Kuck, K. H., Cappato, R., Brugada, J., Camm, A. J., Chen, S.-A., Crijns, H. J. G., Damiano, R. J., Davies, D. W., DiMarco, J., et al. (2012) · Heart Rhythm · doi:10.1016/j.hrthm.2011.12.016 · Cited by 1,456
Self-citationVariants conferring risk of atrial fibrillation on chromosome 4q25
Gudbjartsson, D. F., Arnar, D. O., Helgadottir, A., Gretarsdottir, S., Holm, H., Sigurdsson, A., Jonasdottir, A., Baker, A., Thorleifsson, G., Kristjansson, K., et al. (2007) · Nature · doi:10.1038/nature06007 · Cited by 955
Self-citationFuster, V., Rydén, L. E., Cannom, D. S., Crijns, H. J., Curtis, A. B., Ellenbogen, K. A., Halperin, J. L., Kay, G. N., Le Huezey, J.-Y., Lowe, J. E., et al. (2011) · Circulation · doi:10.1161/cir.0b013e318214876d · Cited by 859
Meta-analysis identifies six new susceptibility loci for atrial fibrillation
Ellinor, P. T., Lunetta, K. L., Albert, C. M., Glazer, N. L., Ritchie, M. D., Smith, A. V., Arking, D. E., Müller-Nurasyid, M., Krijthe, B. P., Lubitz, S. A., et al. (2012) · Nature Genetics · doi:10.1038/ng.2261 · Cited by 601 · cited 11×
“The term was meant to indicate AF in patients for whom subsequent investigations could not demonstrate heart disease, but for many practitioners has become synonymous with “idiopathic AF.””
InfluentialSelf-citationParental atrial fibrillation as a risk factor for atrial fibrillation in offspring
Fox, C. S. (2004) · JAMA · doi:10.1001/jama.291.23.2851 · Cited by 600
Olsson, L. G., Swedberg, K., Ducharme, A., Granger, C. B., Michelson, E. L., McMurray, J. J. V., Puu, M., Yusuf, S., & Pfeffer, M. A. (2006) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2006.01.060 · Cited by 574 · cited 1×
“Clinical studies report that AF is associated with an impaired prognosis in heart failure patients with reduced or preserved left ventricular function.(40-43) Right ventricular dysfunction in chronic obstructive pulmonary disease and other non-cardiac causes of pulmonary hypertension should also not be ignored.”
A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke
Gudbjartsson, D. F., Holm, H., Gretarsdottir, S., Thorleifsson, G., Walters, G. B., Thorgeirsson, G., Gulcher, J., Mathiesen, E. B., Njølstad, I., Nyrnes, A., et al. (2009) · Nature Genetics · doi:10.1038/ng.417 · Cited by 489 · cited 11×
“The term was meant to indicate AF in patients for whom subsequent investigations could not demonstrate heart disease, but for many practitioners has become synonymous with “idiopathic AF.””
Influential
Cited by
2021 ESC Guidelines on cardiovascular disease prevention in clinical practice
Visseren, F. L. J., Mach, F., Smulders, Y. M., Carballo, D., Koskinas, K. C., Bäck, M., Benetos, A., Biffi, A., Boavida, J.-M., Capodanno, D., et al. (2021) · European Heart Journal · doi:10.1093/eurheartj/ehab484 · Cited by 6,485
2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Heart Journal · doi:10.1093/eurheartj/ehw210 · Cited by 6,418
Self-citation2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS
Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., Castella, M., Diener, H.-C., Heidbuchel, H., Hendriks, J., et al. (2016) · European Journal of Cardio-Thoracic Surgery · doi:10.1093/ejcts/ezw313 · Cited by 1,403
Self-citationCommon variants in KCNN3 are associated with lone atrial fibrillation
Ellinor, P. T., Lunetta, K. L., Glazer, N. L., Pfeufer, A., Alonso, A., Chung, M. K., Sinner, M. F., de Bakker, P. I. W., Mueller, M., Lubitz, S. A., et al. (2010) · Nature Genetics · doi:10.1038/ng.537 · Cited by 485
Self-citationRienstra, M., Hobbelt, A. H., Alings, M., Tijssen, J. G. P., Smit, M. D., Brügemann, J., Geelhoed, B., Tieleman, R. G., Hillege, H. L., Tukkie, R., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehx739 · Cited by 313
Self-citation
Metadata
- Authors
- Wyse, D. G., Van Gelder, I. C., Ellinor, P. T., Go, A. S., Kalman, J. M., Narayan, S. M., Nattel, S., Schotten, U., & Rienstra, M.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2014-05
- Volume
- 63
- Issue
- 17
- Pages
- 1715-1723
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W2194176361
- Cited by
- 210
- References
- 14
- FWCI
- 14.53
- Type
- journal article
- Language
- en
- Open access
- bronze
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- Wyse, D. G., Van Gelder, I. C., Ellinor, P. T., Go, A. S., Kalman, J. M., Narayan, S. M., Nattel, S., Schotten, U., & Rienstra, M. (2014). Lone Atrial Fibrillation. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2014.01.023
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