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Cited by 416Physical Activity and HealthCardiovascular and exercise physiologyCardiovascular Effects of Exercise

The DOI matches its Crossref record, with a small difference in title or year; 43 of the 46 references it cites were found in a registry or an index.

Dose of Jogging and Long-Term Mortality

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Schnohr, Peter, O’Keefe, James H., Marott, Jacob L., Lange, Peter, Jensen, Gorm B.·2015·Journal of the American College of Cardiology
DOI 10.1016/j.jacc.2014.11.023
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Abstract

Background People who are physically active have at least a 30% lower risk of death during follow-up compared with those who are inactive. However, the ideal dose of exercise for improving longevity is uncertain.Objectives The aim of this study was to investigate the association between jogging and long-term, all-cause mortality by focusing specifically on the effects of pace, quantity, and frequency of jogging.Methods As part of the Copenhagen City Heart Study, 1,098 healthy joggers and 3,950 healthy nonjoggers have been prospectively followed up since 2001. Cox proportional hazards regression analysis was performed with age as the underlying time scale and delayed entry.Results Compared with sedentary nonjoggers, 1 to 2.4 h of jogging per week was associated with the lowest mortality (multivariable hazard ratio [HR]: 0.29; 95% confidence interval [CI]: 0.11 to 0.80). The optimal frequency of jogging was 2 to 3 times per week (HR: 0.32; 95% CI: 0.15 to 0.69) or ≤1 time per week (HR: 0.29; 95% CI: 0.12 to 0.72). The optimal pace was slow (HR: 0.51; 95% CI: 0.24 to 1.10) or average (HR: 0.38; 95% CI: 0.22 to 0.66). The joggers were divided into light, moderate, and strenuous joggers. The lowest HR for mortality was found in light joggers (HR: 0.22; 95% CI: 0.10 to 0.47), followed by moderate joggers (HR: 0.66; 95% CI: 0.32 to 1.38) and strenuous joggers (HR: 1.97; 95% CI: 0.48 to 8.14).Conclusions The findings suggest a U-shaped association between all-cause mortality and dose of jogging as calibrated by pace, quantity, and frequency of jogging. Light and moderate joggers have lower mortality than sedentary nonjoggers, whereas strenuous joggers have a mortality rate not statistically different from that of the sedentary group.

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Metadata

Authors
Schnohr, P., O’Keefe, J. H., Marott, J. L., Lange, P., & Jensen, G. B.
Affiliations
  • Frederiksberg Hospital (DK)
  • Saint Luke's Hospital (US)
  • University of Copenhagen (DK)
Corresponding author
Schnohr, Peter
ORCID
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2015-02
Volume
65
Issue
5
Pages
411-419
ISSN
0735-1097 (ISSN-L)
DOI
10.1016/j.jacc.2014.11.023
OpenAlex
W12946444
Cited by
416
References
46
Citations by year
2026: 12 · 2025: 24 · 2024: 34 · 2023: 25 · 2022: 41 · 2021: 29 · 2020: 35 · 2019: 44 · 2018: 36 · 2017: 41 · 2016: 46 · 2015: 46
FWCI
41.47
Type
journal article
Language
en
Open access
Licence
Locations
  • Journal of the American College of Cardiology (publishedVersion)
  • PubMed (publishedVersion)
  • Research at the University of Copenhagen (University of Copenhagen) (submittedVersion)
Funders
Danish Heart Foundation
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Physical Activity and Health
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Effects of Exercise
Keywords
jogging, exercise dose, all-cause mortality, running pace, exercise frequency, exercise duration, U-shaped relationship, physical activity, longevity, Copenhagen City Heart Study, sedentary lifestyle, cardiovascular risk factors
MeSH terms
Adult, Aged, Aged, 80 and over, Denmark, Female, Follow-Up Studies, Humans, Jogging, Longevity, Male, Middle Aged, Mortality, Prospective Studies, Registries, Young Adult, Sedentary Behavior

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