Adenosine and clinical forms of neurally-mediated syncope
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In patients with low-adenosine syncope, tilt testing is usually negative.
“Unlike in VVS, tilt testing is usually negative. 4,226”
From 2018 ESC Guidelines for the diagnosis and management of syncope (2018) · cites this paper as [226]
In the 6 July 2015 passage (page unavailable), the paper describes syncope without prodromes and carotid sinus syncope as low-adenosine forms, and reports a high incidence of positive tilt tests in typical VVS. It does not report that tilt tests are usually negative in the low-adenosine forms, so the main assertion is unsupported. (LLM, conf=0.76)
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Cites
Part of this paper’s reference list could not be split into single entries.
Syncope Due to Idiopathic Paroxysmal Atrioventricular Block
Brignole, M., Deharo, J.-C., De Roy, L., Menozzi, C., Blommaert, D., Dabiri, L., Ruf, J., & Guieu, R. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.12.045 · Cited by 147 · see citing works
Self-citationSutton, R., & Brignole, M. (2014) · European Heart Journal · doi:10.1093/eurheartj/ehu255 · Cited by 127 · see citing works
Self-citationDeharo, J., Mechulan, A., Giorgi, R., Franceschi, F., Prévôt, S., Peyrouse, E., Condo, J., By, Y., Ruf, J., Brignole, M., et al. (2012) · Heart · doi:10.1136/heartjnl-2011-301411 · Cited by 54 · see citing works
Self-citationSyncope Without Prodromes in Patients With Normal Heart and Normal Electrocardiogram
Deharo, J.-C., Guieu, R., Mechulan, A., Peyrouse, E., Kipson, N., Ruf, J., Gerolami, V., Devoto, G., Marrè, V., & Brignole, M. (2013) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2013.05.060 · Cited by 53 · see citing works
Self-citationHead-up tilt induced syncope and adenosine A2A receptor gene polymorphism
Saadjian, A., Gérolami, V., Giorgi, R., Mercier, L., Bergé-Lefranc, J. L., Paganelli, F. F., Ibrahim, Z., By, Y., Guéant, J., Lévy, S., et al. (2009) · European Heart Journal · doi:10.1093/eurheartj/ehp126 · Cited by 44 · see citing works
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2018 ESC Guidelines for the diagnosis and management of syncope
Brignole, M., Moya, A., de Lange, F. J., Deharo, J.-C., Elliott, P. M., Fanciulli, A., Fedorowski, A., Furlan, R., Kenny, R. A., Martín, A., et al. (2018) · European Heart Journal · doi:10.1093/eurheartj/ehy037 · Cited by 1,951 · see citing works
Self-citationMechanism of syncope without prodromes with normal heart and normal electrocardiogram
Brignole, M., Guieu, R., Tomaino, M., Iori, M., Ungar, A., Bertolone, C., Unterhuber, M., Bottoni, N., Tesi, F., & Claude Deharo, J. (2017) · Heart Rhythm · doi:10.1016/j.hrthm.2016.08.046 · Cited by 59 · see citing works
Self-citationEfficacy of theophylline in patients affected by low adenosine syncope
Brignole, M., Solari, D., Iori, M., Bottoni, N., Guieu, R., & Deharo, J. C. (2016) · Heart Rhythm · doi:10.1016/j.hrthm.2015.12.016 · Cited by 29 · see citing works
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- Authors
- Guieu, R., Deharo, J.-C., Ruf, J., Mottola, G., Kipson, N., Bruzzese, L., Gerolami, V., Franceschi, F., Ungar, A., Tomaino, M., Iori, M., & Brignole, M.
- Corresponding author
- Brignole, Michele
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2015-07
- Volume
- 66
- Issue
- 2
- Pages
- 204-205
- ISSN
- 0735-1097 (ISSN-L)
- OpenAlex
- W749775541
- Cited by
- 46
- References
- 5
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 4 · 2023: 1 · 2022: 5 · 2021: 8 · 2020: 5 · 2019: 5 · 2018: 8 · 2017: 1 · 2016: 3 · 2015: 3
- FWCI
- 5.05
- Type
- journal article
- Language
- en
- Update notices
- erratum (2015-08-25)
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- Florence Research (University of Florence) (submittedVersion)
- Topics
- Health Sciences › Medicine › Surgery › Cardiovascular Syncope and Autonomic Disorders
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Physiology › Adenosine and Purinergic Signaling
- Keywords
- adenosine, neurally mediated syncope, reflex syncope, cardiovascular health, syncope pathophysiology
- MeSH terms
- Adenosine, Female, Humans, Male, Middle Aged, Syncope, Vasovagal
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