Positive pressure ventilation in the cardiac intensive care unit
Open accessAbstract
Contemporary cardiac intensive care units (CICUs) provide care for an aging and increasingly complex patient population. The medical complexity of this population is partly driven by an increased proportion of patients with respiratory failure needing noninvasive or invasive positive pressure ventilation (PPV). PPV often plays an important role in the management of patients with cardiogenic pulmonary edema, cardiogenic shock, or cardiac arrest, and those undergoing mechanical circulatory support. Noninvasive PPV, when appropriately applied to selected patients, may reduce the need for invasive mechanical PPV and improve survival. Invasive PPV can be lifesaving, but has both favorable and unfavorable interactions with left and right ventricular physiology and carries a risk of complications that influence CICU mortality. Effective implementation of PPV requires an understanding of the underlying cardiac and pulmonary pathophysiology. Cardiologists who practice in the CICU should be proficient with the indications, appropriate selection, potential cardiopulmonary interactions, and complications of PPV.
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Many patients admitted to the CICU require mechanical ventilation.
“with many patients requiring MV,171”
From Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association (2026) · cites this paper as [171]
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Cites
Prone positioning in severe acute respiratory distress syndrome.
Guérin, C., Reignier, J., Richard, J.-C., Beuret, P., Gacouin, A., Boulain, T., Mercier, E., Badet, M., Mercat, A., Baudin, O., et al. (2013) · New England Journal of Medicine · doi:10.1056/nejmoa1214103 · Cited by 4,040 · see citing works
Peek, G. J., Mugford, M., Tiruvoipati, R., Wilson, A., Allen, E., Thalanany, M. M., Hibbert, C. L., Truesdale, A., Clemens, F., Cooper, N., et al. (2009) · The Lancet · doi:10.1016/s0140-6736(09)61069-2 · Cited by 3,395 · see citing works
Neuromuscular Blockers in Early Acute Respiratory Distress Syndrome
Papazian, L., Forel, J.-M., Gacouin, A., Penot-Ragon, C., Perrin, G., Loundou, A., Jaber, S., Arnal, J.-M., Perez, D., Seghboyan, J.-M., et al. (2010) · New England Journal of Medicine · doi:10.1056/nejmoa1005372 · Cited by 2,432 · see citing works
Girardis, M., Busani, S., Damiani, E., Donati, A., Rinaldi, L., Marudi, A., Morelli, A., Antonelli, M., & Singer, M. (2016) · JAMA · doi:10.1001/jama.2016.11993 · Cited by 723 · see citing works
Girard, T. D., Alhazzani, W., Kress, J. P., Ouellette, D. R., Schmidt, G. A., Truwit, J. D., Burns, S. M., Epstein, S. K., Esteban, A., Fan, E., et al. (2017) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201610-2075st · Cited by 387 · see citing works
Flagged first, then by citations
Research works printed but not linked: 120
- [1]Morrow DA, Fang JC, Fintel DJ, Evolution of critical care cardiology: transformation of the cardiovascular intensive care unit and the emerging need for new medical staffing and training models: a scientific statement from the American Heart Association. Circulation 2012; 126: 1408– 28. 22893607
- [2]Katz JN, Shah BR, Volz EM, Evolution of the coronary care unit: clinical characteristics and temporal trends in healthcare delivery and outcomes. Crit Care Med 2010; 38: 375– 81. 20029344
- [3]Morrow DA. Trends in cardiac critical care: reshaping the cardiac intensive care unit. Circ Cardiovasc Qual Outcomes 2017; 10: e004010. 28794123
- [4]Sinha SS, Sjoding MW, Sukul D, Changes in primary noncardiac diagnoses over time among elderly cardiac intensive care unit patients in the United States. Circ Cardiovasc Qual Outcomes 2017; 10: e003616. 28794121 PMC5657300
- [5]Metkus TS, Albaeni A, Chandra-Strobos N, Eid SM. Incidence and prognostic impact of respiratory support in patients with ST-segment elevation myocardial infarction. Am J Cardiol 2017; 119: 171– 7. 27956004 PMC5186403
- [6]Feihl F, Broccard AF. Interactions between respiration and systemic hemodynamics. Part I: basic concepts. Intensive Care Med 2009; 35: 45– 54. 18825367
- [7]Feihl F, Broccard AF. Interactions between respiration and systemic hemodynamics. Part II: practical implications in critical care. Intensive Care Med 2009; 35: 198– 205. 18825366
- [8]Truwitt JD. Lung mechanics. In: Dantzer DR, MacIntyre N, Bakow ED, editors. Comprehensive Respiratory Care. Philadelphia: WB Saunders Co, 1995: 18– 31.
- [9]Coruh B, Tonelli MR, Park DR. Fentanyl-induced chest wall rigidity. Chest 2013; 143: 1145– 6. 23546488
- [10]Grinnan DC, Truwit JD. Clinical review: respiratory mechanics in spontaneous and assisted ventilation. Crit Care 2005; 9: 472– 84. 16277736 PMC1297597
- [12]Esteban A, Anzueto A, Frutos F, Characteristics and outcomes in adult patients receiving mechanical ventilation: a 28-day international study. JAMA 2002; 287: 345– 55. 11790214
- [13]Brower RG, Lanken PN, MacIntyre N, Higher versus Lower positive end-expiratory pressures in patients with the acute respiratory distress syndrome. N Engl J Med 2004; 351: 327– 36. 15269312
- [14]Pang D, Keenan SP, Cook DJ, Sibbald WJ. The effect of positive pressure airway support on mortality and the need for intubation in cardiogenic pulmonary edema: a systematic review. Chest 1998; 114: 1185– 92. 9792593
- [15]Magder SA, Lichtenstein S, Adelman AG. Effect of negative pleural pressure on left ventricular hemodynamics. Am J Cardiol 1983; 52: 588– 93. 6613883
- [16]Rankin JS, Olsen CO, Arentzen CE, The effects of airway pressure on cardiac function in intact dogs and man. Circulation 1982; 66: 108– 20. 7044610
- [17]Cheifetz IM. Cardiorespiratory interactions: the relationship between mechanical ventilation and hemodynamics. Respir Care 2014; 59: 1937– 45. 25389353
- [18]Patzelt J, Zhang Y, Seizer P, Effects of mechanical ventilation on heart geometry and mitral valve leaflet coaptation during percutaneous edge-to-edge mitral valve repair. J Am Coll Cardiol Intv 2016; 9: 151– 9. 26723764
- [19]Tkacova R, Liu PP, Naughton MT, Bradley TD. Effect of continuous positive airway pressure on mitral regurgitant fraction and atrial natriuretic peptide in patients with heart failure. J Am Coll Cardiol 1997; 30: 739– 45. 9283534
- [20]Cassidy SS, Ramanathan M. Dimensional analysis of the left ventricle during PEEP: relative septal and lateral wall displacements. Am J Physiol 1984; 246: H792– 805. 6742144
- [21]Haddad F, Doyle R, Murphy DJ, Hunt SA. Right ventricular function in cardiovascular disease, part II: pathophysiology, clinical importance, and management of right ventricular failure. Circulation 2008; 117: 1717– 31. 18378625
- [22]Robotham JL, Lixfeld W, Holland L, The effects of positive end-expiratory pressure on right and left ventricular performance. Am Rev Respir Dis 1980; 121: 677– 83. 6155813
- [23]Nanas S, Magder S. Adaptations of the peripheral circulation to PEEP. Am Rev Respir Dis 1992; 146: 688– 93. 1519849
- [24]Price LC, Wort SJ, Finney SJ, Marino PS, Brett SJ. Pulmonary vascular and right ventricular dysfunction in adult critical care: current and emerging options for management: a systematic literature review. Crit Care 2010; 14: R169. 20858239 PMC3219266
- [25]Petersson J, Ax M, Frey J, Sanchez-Crespo A, Lindahl SG, Mure M. Positive end-expiratory pressure redistributes regional blood flow and ventilation differently in supine and prone humans. Anesthesiology 2010; 113: 1361– 9. 21068656
- [26]Tomashefski JF Jr., Davies P, Boggis C, Greene R, Zapol WM, Reid LM. The pulmonary vascular lesions of the adult respiratory distress syndrome. Am J Pathol 1983; 112: 112– 26. 6859225 PMC1916312
- [27]Green EM, Givertz MM. Management of acute right ventricular failure in the intensive care unit. Curr Heart Fail Rep 2012; 9: 228– 35. 22805893
- [28]Marini JJ. Dynamic hyperinflation and autopositive end-expiratory pressure: lessons learned over 30 years. Am J Respir Crit Care Med 2011; 184: 756– 62. 21700908
- [29]Hernandez G, Roca O, Colinas L. High-flow nasal cannula support therapy: new insights and improving performance. Crit Care 2017; 21: 62. 28320436 PMC5359952
- [30]Lee JH, Rehder KJ, Williford L, Cheifetz IM, Turner DA. Use of high flow nasal cannula in critically ill infants, children, and adults: a critical review of the literature. Intensive Care Med 2013; 39: 247– 57. 23143331
- [31]Frat JP, Thille AW, Mercat A, High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med 2015; 372: 2185– 96. 25981908
- [32]Stephan F, Barrucand B, Petit P, High-flow nasal oxygen vs noninvasive positive airway pressure in hypoxemic patients after cardiothoracic surgery: a randomized clinical trial. JAMA 2015; 313: 2331– 9. 25980660
- [33]Spoletini G, Alotaibi M, Blasi F, Hill NS. Heated humidified high-flow nasal oxygen in adults: mechanisms of action and clinical implications. Chest 2015; 148: 253– 61. 25742321
- [34]Organized Jointly by the American Thoracic Society, the European Respiratory Society, the European Society of Intensive Care Medicine, and the Société de Réanimation de Langue Française, and approved by the ATS Board of Directors, December 2000. International consensus conferences in intensive care medicine: noninvasive positive pressure ventilation in acute Respiratory failure. Am J Respir Crit Care Med 2001; 163: 283– 91.11208659
- [35]Girault C, Briel A, Benichou J, Interface strategy during noninvasive positive pressure ventilation for hypercapnic acute respiratory failure. Crit Care Med 2009; 37: 124– 31. 19050635
- [36]Hess D, Kacmarek RM. Essentials of Mechanical Ventilation. Third edition. New York: McGraw Hill Education, Medical Publishing Division, 2014.
- [38]Stub D, Smith K, Bernard S, Air versus oxygen in ST-segment-elevation myocardial infarction. Circulation 2015; 131: 2143– 50. 26002889
- [39]Roberts BW, Kilgannon JH, Hunter BR, Association between early hyperoxia exposure after resuscitation from cardiac arrest and neurological disability: prospective multicenter protocol-directed cohort study. Circulation 2018; 137: 2114– 24. 29437118 PMC6370332
- [40]Gay PC. Complications of noninvasive ventilation in acute care. Respir Care 2009; 54: 246– 57. 19173756
- [41]Gray A, Goodacre S, Newby DE, Noninvasive ventilation in acute cardiogenic pulmonary edema. N Engl J Med 2008; 359: 142– 51. 18614781
- [42]Chatburn RL, El-Khatib M, Mireles-Cabodevila E. A taxonomy for mechanical ventilation: 10 fundamental maxims. Respir Care 2014; 59: 1747– 63. 25118309
- [43]Porhomayon J, El-Solh AA, Nader ND. Applications of airway pressure release ventilation. Lung 2010; 188: 87– 96. 20049471
- [44]Scharf SM, Bianco JA, Tow DE, Brown R. The effects of large negative intrathoracic pressure on left ventricular function in patients with coronary artery disease. Circulation 1981; 63: 871– 5. 7471344
- [45]Corredor C, Jaggar SI. Ventilator management in the cardiac intensive care unit. Cardiol Clin 2013; 31: 619– 36, ix. 24188225
- [46]Dursun A, Okumus N, Erol S, Bayrak T, Zenciroglu A. Effect of ventilation support on oxidative stress and ischemia-modified albumin in neonates. Am J Perinatol 2016; 33: 136– 42. 26301964
- [47]Goligher EC, Dres M, Fan E, Mechanical ventilation-induced diaphragm atrophy strongly impacts clinical outcomes. Am J Respir Crit Care Med 2018; 197: 204– 13. 28930478
- [48]Shorofsky M, Jayaraman D, Lellouche F, Husa R, Lipes J. Mechanical ventilation with high tidal volume and associated mortality in the cardiac intensive care unit. Acute Card Care 2014; 16: 9– 14. 24552224
- [49]Chadda K, Annane D, Hart N, Gajdos P, Raphael JC, Lofaso F. Cardiac and respiratory effects of continuous positive airway pressure and noninvasive ventilation in acute cardiac pulmonary edema. Crit Care Med 2002; 30: 2457– 61. 12441754
- [50]Masip J, Betbese AJ, Paez J, Non-invasive pressure support ventilation versus conventional oxygen therapy in acute cardiogenic pulmonary oedema: a randomised trial. Lancet 2000; 356: 2126– 32. 11191538
- [51]Park M, Sangean MC, Volpe Mde S, Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema. Crit Care Med 2004; 32: 2407– 15. 15599144
- [52]Kulkarni VT, Kim N, Dai Y, Hospital variation in noninvasive positive pressure ventilation for acute decompensated heart failure. Circ Heart Fail 2014; 7: 427– 33. 24633829 PMC4386575
- [53]Vital FM, Ladeira MT, Atallah AN. Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. Cochrane Database Syst Rev 2013: CD005351. 23728654
- [54]Weng CL, Zhao YT, Liu QH, Meta-analysis: Noninvasive ventilation in acute cardiogenic pulmonary edema. Ann Intern Med 2010; 152: 590– 600. 20439577
- [55]Mebazaa A, Yilmaz MB, Levy P, Recommendations on pre-hospital and early hospital management of acute heart failure: a consensus paper from the Heart Failure Association of the European Society of Cardiology, the European Society of Emergency Medicine and the Society of Academic Emergency Medicine–short version. Eur Heart J 2015; 36: 1958– 66. 25998514
- [56]Anton A, Guell R, Gomez J, Predicting the result of noninvasive ventilation in severe acute exacerbations of patients with chronic airflow limitation. Chest 2000; 117: 828– 33. 10713013
- [57]Ariza Sole A, Salazar-Mendiguchia J, Lorente-Tordera V, Invasive mechanical ventilation in acute coronary syndromes in the era of percutaneous coronary intervention. Eur Heart J Acute Cardiovasc Care 2013; 2: 109– 17. 24222819 PMC3821810
- [58]Thiele H, Zeymer U, Neumann FJ, Intraaortic balloon support for myocardial infarction with cardiogenic shock. N Engl J Med 2012; 367: 1287– 96. 22920912
- [59]Puymirat E, Fagon JY, Aegerter P, Cardiogenic shock in intensive care units: evolution of prevalence, patient profile, management and outcomes, 1997-2012. Eur J Heart Fail 2017; 19: 192– 200. 27709722
- [60]Fessler HE, Brower RG, Wise RA, Permutt S. Mechanism of reduced LV afterload by systolic and diastolic positive pleural pressure. J Appl Physiol (1985) 1988; 65: 1244– 50. 3053581
- [61]Grace MP, Greenbaum DM. Cardiac performance in response to PEEP in patients with cardiac dysfunction. Crit Care Med 1982; 10: 358– 60. 7042203
- [62]Bellone A, Barbieri A, Ricci C, Acute effects of non-invasive ventilatory support on functional mitral regurgitation in patients with exacerbation of congestive heart failure. Intensive Care Med 2002; 28: 1348– 50. 12209288
- [63]Calvin JE, Driedger AA, Sibbald WJ. Positive end-expiratory pressure (PEEP) does not depress left ventricular function in patients with pulmonary edema. Am Rev Respir Dis 1981; 124: 121– 8. 7020510
- [64]Wiesen J, Ornstein M, Tonelli AR, Menon V, Ashton RW. State of the evidence: mechanical ventilation with PEEP in patients with cardiogenic shock. Heart 2013; 99: 1812– 7. 23539555 PMC4096289
- [65]Peters J. Mechanical ventilation with PEEP–a unique therapy for failing hearts. Intensive Care Med 1999; 25: 778– 80. 10447533
- [66]Kontoyannis DA, Nanas JN, Kontoyannis SA, Stamatelopoulos SF, Moulopoulos SD. Mechanical ventilation in conjunction with the intra-aortic balloon pump improves the outcome of patients in profound cardiogenic shock. Intensive Care Med 1999; 25: 835– 8. 10447541
- [67]Mathru M, Rao TL, El-Etr AA, Pifarre R. Hemodynamic response to changes in ventilatory patterns in patients with normal and poor left ventricular reserve. Crit Care Med 1982; 10: 423– 6. 7044680
- [68]Hoeper MM, Granton J. Intensive care unit management of patients with severe pulmonary hypertension and right heart failure. Am J Respir Crit Care Med 2011; 184: 1114– 24. 21700906
- [69]Aqel RA, Aljaroudi W, Hage FG, Tallaj J, Rayburn B, Nanda NC. Left ventricular collapse secondary to pericardial effusion treated with pericardicentesis and percutaneous pericardiotomy in severe pulmonary hypertension. Echocardiography 2008; 25: 658– 61. 18652010
- [70]Balanos GM, Talbot NP, Dorrington KL, Robbins PA. Human pulmonary vascular response to 4 h of hypercapnia and hypocapnia measured using Doppler echocardiography. J Appl Physiol (1985) 2003; 94: 1543– 51. 12482766
- [71]Jardin F, Vieillard-Baron A. Right ventricular function and positive pressure ventilation in clinical practice: from hemodynamic subsets to respirator settings. Intensive Care Med 2003; 29: 1426– 34. 12910335
- [72]Paternot A, Repesse X, Vieillard-Baron A. Rationale and description of right ventricle-protective ventilation in ARDS. Respir Care 2016; 61: 1391– 6. 27484108
- [73]Malik AB, Kidd BS. The independent effects of changes in H + and CO 2 concentrations on pulmonary hemodynamics of intact dogs. Can J Physiol Pharmacol 1973; 51: 139– 47. 4697732
- [74]Grasso S, Terragni P, Mascia L, Airway pressure-time curve profile (stress index) detects tidal recruitment/hyperinflation in experimental acute lung injury. Crit Care Med 2004; 32: 1018– 27. 15071395
- [75]Henderson WR, Chen L, Amato MBP, Brochard LJ. Fifty years of research in ARDS. Respiratory mechanics in acute respiratory distress syndrome. Am J Respir Crit Care Med 2017; 196: 822– 33. 28306327
- [76]Vieillard-Baron A, Charron C, Caille V, Belliard G, Page B, Jardin F. Prone positioning unloads the right ventricle in severe ARDS. Chest 2007; 132: 1440– 6. 17925425
- [77]Harjola VP, Mebazaa A, Celutkiene J, Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology. Eur J Heart Fail 2016; 18: 226– 41. 26995592
- [78]Ho AM, Graham CA, Ng CS, Timing of tracheal intubation in traumatic cardiac tamponade: a word of caution. Resuscitation 2009; 80: 272– 4. 19059695
- [79]Thiagarajan RR, Barbaro RP, Rycus PT, Extracorporeal Life Support Organization Registry International Report 2016. ASAIO J 2017; 63: 60– 7. 27984321
- [80]Miller PE, Solomon MA, McAreavey D. Advanced percutaneous mechanical circulatory support devices for cardiogenic shock. Crit Care Med 2017; 45: 1922– 9. 28857849 PMC5640487
- [82]Marhong JD, Telesnicki T, Munshi L, Del Sorbo L, Detsky M, Fan E. Mechanical ventilation during extracorporeal membrane oxygenation. An international survey. Ann Am Thorac Soc 2014; 11: 956– 61. 24983618
- [83]Schmidt M, Pellegrino V, Combes A, Scheinkestel C, Cooper DJ, Hodgson C. Mechanical ventilation during extracorporeal membrane oxygenation. Crit Care 2014; 18: 203. 24447458 PMC4057516
- [85]Preslaski CR, Lat I, MacLaren R, Poston J. Pharmacist contributions as members of the multidisciplinary ICU team. Chest 2013; 144: 1687– 95. 24189862
- [86]Shulman R, McKenzie CA, Landa J, Pharmacis’s review and outcomes: Treatment-enhancing contributions tallied, evaluated, and documented (PROTECTED-UK). J Crit Care 2015; 30: 808– 13. 25971871
- [87]deBacker J, Hart N, Fan E. Neuromuscular blockade in the 21st century management of the critically ill patient. Chest 2017; 151: 697– 706. 27818334
- [88]Barr J, Fraser GL, Puntillo K, Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med 2013; 41: 263– 306. 23269131
- [89]Cavalcanti AB, Suzumura ÉA, Laranjeira LN, for the Writing Group for the Alveolar Recruitment for Acute Respiratory Distress Syndrome Trial Investigators. Effect of lung recruitment and titrated positive end-expiratory pressure (PEEP) vs low PEEP on mortality in patients with acute respiratory distress syndrome: a randomized clinical trial. JAMA 2017; 318: 1335– 45. 28973363 PMC5710484
- [90]Meade MO, Cook DJ, Guyatt GH, Ventilation strategy using low tidal volumes, recruitment maneuvers, and high positive end-expiratory pressure for acute lung injury and acute respiratory distress syndrome: a randomized controlled trial. JAMA 2008; 299: 637– 45. 18270352
- [91]Briel M, Meade M, Mercat A, Higher vs lower positive end-expiratory pressure in patients with acute lung injury and acute respiratory distress syndrome: systematic review and meta-analysis. JAMA 2010; 303: 865– 73. 20197533
- [92]Bollen CW, van Well GT, Sherry T, High frequency oscillatory ventilation compared with conventional mechanical ventilation in adult respiratory distress syndrome: a randomized controlled trial [ ISRCTN24242669]. Crit Care 2005; 9: R430– 9. 16137357 PMC1269459
- [93]Derdak S, Mehta S, Stewart TE, High-frequency oscillatory ventilation for acute respiratory distress syndrome in adults: a randomized, controlled trial. Am J Respir Crit Care Med 2002; 166: 801– 8. 12231488
- [94]Sud S, Sud M, Friedrich JO, High frequency oscillation in patients with acute lung injury and acute respiratory distress syndrome (ARDS): systematic review and meta-analysis. BMJ 2010; 340: c2327. 20483951
- [96]Taccone P, Pesenti A, Latini R, Prone positioning in patients with moderate and severe acute respiratory distress syndrome: a randomized controlled trial. JAMA 2009; 302: 1977– 84. 19903918
- [97]Sud S, Friedrich JO, Taccone P, Prone ventilation reduces mortality in patients with acute respiratory failure and severe hypoxemia: systematic review and meta-analysis. Intensive Care Med 2010; 36: 585– 99. 20130832
- [99]Pelosi P, Brazzi L, Gattinoni L. Prone position in acute respiratory distress syndrome. Eur Respir J 2002; 20: 1017– 28. 12412699
- [100]Taylor RW, Zimmerman JL, Dellinger RP, Low-dose inhaled nitric oxide in patients with acute lung injury: a randomized controlled trial. JAMA 2004; 291: 1603– 9. 15069048
- [101]Adhikari NK, Burns KE, Friedrich JO, Granton JT, Cook DJ, Meade MO. Effect of nitric oxide on oxygenation and mortality in acute lung injury: systematic review and meta-analysis. BMJ 2007; 334: 779. 17383982 PMC1852043
- [102]Lundin S, Mang H, Smithies M, Stenqvist O, Frostell C, for the European Study Group of Inhaled Nitric Oxide. Inhalation of nitric oxide in acute lung injury: results of a European multicentre study. Intensive Care Med 1999; 25: 911– 9. 10501745
- [103]Gries A, Herr A, Kirsch S, Inhaled nitric oxide inhibits platelet-leukocyte interactions in patients with acute respiratory distress syndrome. Crit Care Med 2003; 31: 1697– 704. 12794407
- [104]Gebistorf F, Karam O, Wetterslev J, Afshari A. Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults. Cochrane Database Syst Rev 2016: CD002787. PMC6464789 27347773
- [105]Slutsky AS, Ranieri VM. Ventilator-induced lung injury. N Engl J Med 2013; 369: 2126– 36. 24283226
- [106]Serpa Neto A, Cardoso SO, Manetta JA, Association between use of lung-protective ventilation with lower tidal volumes and clinical outcomes among patients without acute respiratory distress syndrome: a meta-analysis. JAMA 2012; 308: 1651– 9. 23093163
- [107]Neto AS, Simonis FD, Barbas CS, Lung-protective ventilation with low tidal volumes and the occurrence of pulmonary complications in patients without acute respiratory distress syndrome: a systematic review and individual patient data analysis. Crit Care Med 2015; 43: 2155– 63. 26181219
- [108]Thompson BT, Chambers RC, Liu KD. Acute respiratory distress syndrome. N Engl J Med 2017; 377: 562– 72. 28792873
- [109]Decailliot F, Demoule A, Maggiore SM, Jonson B, Duvaldestin P, Brochard L. Pressure-volume curves with and without muscle paralysis in acute respiratory distress syndrome. Intensive Care Med 2006; 32: 1322– 8. 16826390
- [110]Talmor D, Sarge T, Malhotra A, Mechanical ventilation guided by esophageal pressure in acute lung injury. N Engl J Med 2008; 359: 2095– 104. 19001507 PMC3969885
- [111]Safdar N, Dezfulian C, Collard HR, Saint S. Clinical and economic consequences of ventilator-associated pneumonia: a systematic review. Crit Care Med 2005; 33: 2184– 93. 16215368
- [112]Ensminger SA, Wright RS, Baddour LM, Afessa B. Suspected ventilator-associated pneumonia in cardiac patients admitted to the coronary care unit. Mayo Clin Proc 2006; 81: 32– 5. 16438476
- [113]Alexiou VG, Ierodiakonou V, Dimopoulos G, Falagas ME. Impact of patient position on the incidence of ventilator-associated pneumonia: a meta-analysis of randomized controlled trials. J Crit Care 2009; 24: 515– 22. 19327314
- [114]Girard TD, Kress JP, Fuchs BD, Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008; 371: 126– 34. 18191684
- [115]Morris AC, Hay AW, Swann DG, Reducing ventilator-associated pneumonia in intensive care: impact of implementing a care bundle. Crit Care Med 2011; 39: 2218– 24. 21666444
- [116]Muscedere J, Rewa O, McKechnie K, Jiang X, Laporta D, Heyland DK. Subglottic secretion drainage for the prevention of ventilator-associated pneumonia: a systematic review and meta-analysis. Crit Care Med 2011; 39: 1985– 91. 21478738
- [117]Dasta JF, McLaughlin TP, Mody SH, Piech CT. Daily cost of an intensive care unit day: the contribution of mechanical ventilation. Crit Care Med 2005; 33: 1266– 71. 15942342
- [118]Seymour CW, Martinez A, Christie JD, Fuchs BD. The outcome of extubation failure in a community hospital intensive care unit: a cohort study. Crit Care 2004; 8: R322– 7. 15469575 PMC1065021
- [119]Liu J, Shen F, Teboul JL, Cardiac dysfunction induced by weaning from mechanical ventilation: incidence, risk factors, and effects of fluid removal. Crit Care 2016; 20: 369. 27836002 PMC5106814
- [121]Hernandez G, Vaquero C, Colinas L, Effect of postextubation high-flow nasal cannula vs noninvasive ventilation on reintubation and post-extubation respiratory failure in high-risk patients: a randomized clinical trial. JAMA 2016; 316: 1565– 74. 27706464
- [122]Tobin MJ. Extubation and the myth of “minimal ventilator settings.” Am J Respir Crit Care Med 2012; 185: 349– 50. 22336673
- [123]McConville JF, Kress JP. Weaning patients from the ventilator. N Engl J Med 2012; 367: 2233– 9. 23215559
- [124]Ruiz-Bailen M, Cobo-Molinos J, Castillo-Rivera A, Stress echocardiography in patients who experienced mechanical ventilation weaning failure. J Crit Care 2017; 39: 66– 71. 28219811
- [125]Ouellette DR, Patel S, Girard TD, Liberation from mechanical ventilation in critically ill adults: an official American College of Chest Physicians/American Thoracic Society clinical practice guideline: inspiratory pressure augmentation during spontaneous breathing trials, protocols minimizing sedation, and noninvasive ventilation immediately after extubation. Chest 2017; 151: 166– 80. 27818331
- [126]Thille AW, Harrois A, Schortgen F, Brun-Buisson C, Brochard L. Outcomes of extubation failure in medical intensive care unit patients. Crit Care Med 2011; 39: 2612– 8. 21765357
- [127]Esteban A, Frutos-Vivar F, Ferguson ND, Noninvasive positive-pressure ventilation for respiratory failure after extubation. N Engl J Med 2004; 350: 2452– 60. 15190137
Cited by
Sorted by citations
Vest, A. R., DiDomenico, R. J., Lichtenstein, L., Slater, T., Ekpo, E., Damluji, A. A., Bohula, E., Alviar, C. L., on behalf of the American Heart Association Acute Cardiac Care and General Cardiology Committee of the Council on Clinical Cardiology, & Council on Cardiovascular and Stroke Nursing (2026) · Circulation · doi:10.1161/cir.0000000000001405 · Cited by 15 · see citing works
Self-citation
- Authors
- Alviar, C. L., Miller, P. E., McAreavey, D., Katz, J. N., Lee, B., Moriyama, B., Soble, J., van Diepen, S., Solomon, M. A., & Morrow, D. A.
- Affiliations
- University of Florida Health (US)
- National Institutes of Health (US)
- University of North Carolina at Chapel Hill (US)
- University of Pittsburgh (US)
- Rush University Medical Center (US)
- Brigham and Women's Hospital (US)
- Corresponding author
- Morrow, David A.
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2018-09
- Volume
- 72
- Issue
- 13
- Pages
- 1532-1553
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC11032173
- OpenAlex
- W2890571093
- Cited by
- 271
- References
- 5
- Citations by year
- 2026: 51 · 2025: 56 · 2024: 44 · 2023: 27 · 2022: 26 · 2021: 35 · 2020: 17 · 2019: 15
- FWCI
- 2.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH Clinical Center
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Respiratory Support and Mechanisms
- Physical Sciences › Engineering › Biomedical Engineering › Mechanical Circulatory Support Devices
- Health Sciences › Medicine › Surgery › Hemodynamic Monitoring and Therapy
- Keywords
- positive pressure ventilation, cardiac intensive care, cardiogenic pulmonary edema, cardiogenic shock, cardiac arrest, mechanical circulatory support, non-invasive ventilation, invasive mechanical ventilation, cardiorespiratory interaction
- MeSH terms
- Algorithms, Hypoxia, Cardiac Output, Coronary Care Units, Coronary Circulation, Heart Failure, Hemodynamics, Humans, Positive-Pressure Respiration, Respiration, Shock, Cardiogenic, Ventilator Weaning, Ventricular Function
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review