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Cited by 769

The DOI matches its Crossref record; 104 of the 104 references it cites were found in a registry or an index.

Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options

Open access
Taqueti, Viviany R., Di Carli, Marcelo F.·2018·Journal of the American College of Cardiology

Abstract

Coronary microvascular disease (CMD) refers to the subset of disorders affecting the structure and function of the coronary microcirculation, is prevalent in patients across a broad spectrum of cardiovascular risk factors, and is associated with increased risk of adverse events. Contemporary evidence supports that most patients with CMD also have macrovessel atherosclerosis, which has important implications for their prognosis and management. In this state-of-the-art review, we summarize the pathophysiology of CMD, provide an update of diagnostic testing strategies, and classify CMD into phenotypes according to severity and coexistence with atherosclerosis. We examine emerging data highlighting the significance of CMD in specific populations, including obesity and insulin resistance, myocardial injury and heart failure with preserved ejection fraction, and nonobstructive and obstructive coronary artery disease. Finally, we discuss the role of CMD as a potential target for novel interventions beyond conventional approaches, representing a new frontier in cardiovascular disease reduction.

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Crossref · 10.1016/j.jacc.2018.09.042

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Metadata

Authors
Taqueti, V. R., & Di Carli, M. F.
Venue
Journal of the American College of Cardiology
Publisher
Elsevier BV
Published
2018-11
Volume
72
Issue
21
Pages
2625-2641
ISSN
0735-1097 (ISSN-L)
OpenAlex
W2900705378
Cited by
769
References
104
FWCI
30.40
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options. https://app.cochat.ai/papers/10.1016/j.jacc.2018.09.042
The paper
Taqueti, V. R., & Di Carli, M. F. (2018). Coronary Microvascular Disease Pathogenic Mechanisms and Therapeutic Options. Journal of the American College of Cardiology. https://doi.org/10.1016/j.jacc.2018.09.042

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.