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2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: Executive Summary
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“According to the 2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease, there is likely no lower limit on the amount of moderate-to-vigorous physical activity at which benefits for ASCVD risk start to accrue, and effort should be made to promote achievement of the minimum recommended amount of physical activity (44).”
From 2021 ACC Expert Consensus Decision Pathway on the Management of ASCVD Risk Reduction in Patients With Persistent Hypertriglyceridemia (2021) · cites this paper as [44]
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Tarn, D. M., Pletcher, M. J., Tosqui, R., Fernández, A., Tseng, C., Moriconi, R., Bell, D. S., Barrientos, M., Turner, J. A., & Schwartz, J. B. (2021) · Preventive Medicine Reports · doi:10.1016/j.pmedr.2021.101357 · Cited by 24
Giugliano, D., Ceriello, A., De Nicola, L., Perrone‐Filardi, P., Cosentino, F., & Esposito, K. (2020) · Diabetes, Obesity and Metabolism · doi:10.1111/dom.13881 · Cited by 22
GLP-1 receptor agonists in diabetic kidney disease
Michos, E. D., & Tuttle, K. R. (2021) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.18771220 · Cited by 23
Self-citationOptimal cardiovascular health is associated with slower cognitive decline
Ferreira, N. V., Gonçalves, N. G., Szlejf, C., Goulart, A. C., Santos, I. S., Duncan, B. B., Schmidt, M. I., Barreto, S. M., Caramelli, P., Feter, N., et al. (2023) · European Journal of Neurology · doi:10.1111/ene.16139 · Cited by 22
Current Antithrombotic Treatments for Cardiovascular Diseases: A Comprehensive Review
Galanti, K., Marino, M. D., Mansour, D., Testa, S., Rossi, D., Scollo, C., Magnano, R., Pezzi, L., D’Alleva, A., Forlani, D., et al. (2024) · Reviews in Cardiovascular Medicine · doi:10.31083/j.rcm2508281 · Cited by 24
“…Heart Association guidelines have identified age as a discriminating factor: patients with high cardiovascular risk without an increased bleeding risk aged between 40 and 70 years might be considered for primary prevention, with low class of recommendation (Class IIB, Level of Evidence A) [15].”
BackgroundStatin use and liver-related prognosis among patients with MASLD
Yun, B., Park, H., Lee, J., Kim, B. K., & Yoon, J. (2024) · JHEP Reports · doi:10.1016/j.jhepr.2024.101313 · Cited by 23
“12 Statins, commonly prescribed as 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors to prevent CVDs, 13 are also recognized for their anti-in fl ammatory and anti fi brotic properties, which may help in mitigating the progression of liver fi brosis in patients with MASLD; 14 however, the use…”
Cardiovascular disease in women: traditional and sex-specific risk factors
Appelman, Y., Gulati, M., van Lennep, J. E. R., Shaw, L. J., & Merz, C. N. B. (2025) · European Heart Journal · doi:10.1093/eurheartj/ehaf1001 · Cited by 31
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Validating the NIH LDL-C equation in a specialized lipid cohort: Does it add up?
Higgins, V., Leiter, L. A., Delaney, S. R., & Beriault, D. R. (2021) · Clinical Biochemistry · doi:10.1016/j.clinbiochem.2021.10.003 · Cited by 23
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Garshick, M. S., Drenkova, K., Barrett, T. J., Schlamp, F., Fisher, E. A. A., Katz, S. D., Jelić, S., Neimann, A. L., Scher, J. U., Krueger, J. G., et al. (2021) · Journal of Investigative Dermatology · doi:10.1016/j.jid.2021.07.190 · Cited by 23
Kumar, R., Joseph, B., Pazdernik, V., Geske, J. R., Núñez, N. A., Pahwa, M., KASHANI, K. B., Veldić, M., Betcher, H. K., Moore, K. M., et al. (2022) · Journal of Clinical Psychopharmacology · doi:10.1097/jcp.0000000000001632 · Cited by 25
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“11 As such, the lower age of patients in this analysis [mean age = 41.3 years] may have impacted on the high percentage of patients within the low baseline 10-year ASCVD risk score group [80%]; however, after stratifying patients by age [<40 vs ≥40 years of age], it was observed that the inclusion…”
InfluentialPark, K. E., Minissian, M., Wei, J., Saade, G. R., & Smith, G. N. (2020) · Clinical Cardiology · doi:10.1002/clc.23374 · Cited by 23
Dietary sodium intake and cortisol measurements
Chen, A., Haas, A. V., Williams, G. H., & Vaidya, A. (2020) · Clinical Endocrinology · doi:10.1111/cen.14262 · Cited by 23
Leong, D. P., Yusuf, R., Iqbal, R., Avezum, Á., Yusufali, A., Rosengren, A., Chifamba, J., Lanas, F. T., Dı́az, M. L., Miranda, J. J., et al. (2025) · The Lancet Global Health · doi:10.1016/s2214-109x(25)00155-x · Cited by 26
Cardiovascular inflammaging: Mechanisms, consequences, and therapeutic perspectives
Spray, L., Richardson, G. D., Haendeler, J., Altschmied, J., Rumampouw, V., Wallis, S. B., Georgiopoulos, G. A., White, S. J., Unsworth, A. J., Stellos, K., et al. (2025) · Cell Reports Medicine · doi:10.1016/j.xcrm.2025.102264 · Cited by 28
Cardiovascular Risk Factors: It's Time to Focus on Variability!
Barnett, M. P., & Bangalore, S. (2020) · Journal of Lipid and Atherosclerosis · doi:10.12997/jla.2020.9.2.255 · Cited by 23
Lei, M., Wu, Y., Chung, S., Chen, C.-C., Chen, W.-C., & Hsu, Y.-C. (2020) · Journal of Atherosclerosis and Thrombosis · doi:10.5551/jat.59386 · Cited by 22
How to Diagnose and Manage Radiation Cardiotoxicity
Ganatra, S., Chatur, S., & Nohria, A. (2020) · JACC CardioOncology · doi:10.1016/j.jaccao.2020.07.010 · Cited by 22
The dawn of the four-drug era? SGLT2 inhibition in heart failure with reduced ejection fraction
Genuardi, M. V., & Mather, P. J. (2021) · Therapeutic Advances in Cardiovascular Disease · doi:10.1177/17539447211002678 · Cited by 25
Munjral, S., Ahluwalia, P., Jamthikar, A. D., Puvvula, A., Saba, L., Faa, G., Singh, I. M., Chadha, P. S., Turk, M., Johri, A. M., et al. (2021) · Frontiers in Bioscience-Landmark · doi:10.52586/5026 · Cited by 22
“It is therefore recommended for these individuals to have a mindful food intake [ 29].”
BackgroundPark, C. S., Yang, H., Han, K., Lee, H., Kang, J., Han, J., Park, K. W., Kang, H., Koo, B., & Kim, H.-S. (2023) · Journal of Advanced Research · doi:10.1016/j.jare.2023.05.003 · Cited by 23
“Therefore, current guidelines recommend lowering LDL cholesterol levels to prevent recurrent ASCVD, as well as for primary prevention in individuals at high risk of ASCVD [13–15].”
BackgroundMcDoom, M. M., Cooper, L. A., Hsu, Y., Singh, A., Perin, J., & Thornton, R. L. J. (2020) · Journal of General Internal Medicine · doi:10.1007/s11606-020-05671-y · Cited by 24
Cardioprotective Strategies to Prevent Cancer Treatment-Related Cardiovascular Toxicity: a Review
Upshaw, J. N. (2020) · Current Oncology Reports · doi:10.1007/s11912-020-00923-w · Cited by 22
Umbrella Review on Non-Statin Lipid-Lowering Therapy
Beshir, S. A., Hussain, N., Elnour, A. A., & Said, A. S. A. (2021) · Journal of Cardiovascular Pharmacology and Therapeutics · doi:10.1177/10742484211002943 · Cited by 21
Metadata
- Authors
- Arnett, D. K., Blumenthal, R. S., Albert, M. A., Buroker, A. B., Goldberger, Z. D., Hahn, E. J., Himmelfarb, C. D., Khera, A., Lloyd-Jones, D., McEvoy, J. W., Michos, E. D., Miedema, M. D., Muñoz, D., Smith, S. C., Virani, S. S., Williams, K. A., Yeboah, J., & Ziaeian, B.
- ORCID
- Venue
- Journal of the American College of Cardiology
- Publisher
- Elsevier BV
- Published
- 2019-09
- Volume
- 74
- Issue
- 10
- Pages
- 1376-1414
- ISSN
- 0735-1097 (ISSN-L)
- PMC
- PMC8344373
- OpenAlex
- W2984766121
- Cited by
- 1,193
- References
- 286
- Citations by year
- 2026: 87 · 2025: 140 · 2024: 131 · 2023: 167 · 2022: 191 · 2021: 207 · 2020: 191 · 2019: 79
- FWCI
- 153.80
- Type
- journal article
- Language
- en
- Update notices
- Open access
- bronze
- doi.org
- Licence
- Locations
- Journal of the American College of Cardiology (publishedVersion)
- eScholarship (California Digital Library) (submittedVersion)
- Funders
- American Heart Association (17SDG33630113)
- National Institutes of Health (KL2TR001882)
- National Center for Advancing Translational Sciences
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Health Promotion and Cardiovascular Prevention
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiovascular Health and Risk Factors
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Lipoproteins and Cardiovascular Health
- Keywords
- primary prevention, cardiovascular disease, cardiovascular risk factors, cardiovascular disease prevention
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