Cited by 647Food Allergy and Anaphylaxis ResearchDrug-Induced Adverse ReactionsEosinophilic Esophagitis

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9. Food allergy

Sicherer, Scott H., Sampson, Hugh A.·2006·Journal of Allergy and Clinical Immunology

DOI 10.1016/j.jaci.2005.05.048

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Abstract

Food allergy, defined as an adverse immune response to food proteins, affects as many as 6% of young children and 3% to 4% of adults. Food-induced allergic reactions are responsible for a variety of symptoms involving the skin, gastrointestinal tract, and respiratory tract and might be caused by IgE-mediated and non-IgE-mediated (cellular) mechanisms. Our understanding of how food allergy represents an abrogation of normal oral tolerance is evolving. Although any food can provoke a reaction, relatively few foods are responsible for the vast majority of significant food-induced allergic reactions: milk, egg, peanuts, tree nuts, fish, and shellfish. A systematic approach to diagnosis includes a careful history, followed by laboratory studies, elimination diets, and often food challenges to confirm a diagnosis. Many food allergens have been characterized at a molecular level, which has increased our understanding of the immunopathogenesis of food allergy and might soon lead to novel diagnostic and therapeutic approaches. Currently, management of food allergies consists of educating the patient to avoid ingesting the responsible allergen and to initiate therapy in case of an unintended ingestion.

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Proteine im Wein als potenzielle Allergene?
Wigand, P., & Decker, H. (2012) · Springer eBooks · doi:10.1007/978-3-8274-2887-5_17

Authors: Sicherer, S. H., & Sampson, H. A.
Affiliations: Mount Sinai Hospital (US)
Icahn School of Medicine at Mount Sinai (US)
Corresponding author: Sicherer, Scott H.
ORCID: Sicherer, Scott H.
Venue: Journal of Allergy and Clinical Immunology
Publisher: Elsevier BV
Published: 2006-02
Volume: 117
Issue: 2
Pages: S470-S475
ISSN: 0091-6749 (ISSN-L)
DOI: 10.1016/j.jaci.2005.05.048
OpenAlex: W2146550421
Cited by: 647
References: 139
Citations by year: 2026: 4 · 2025: 8 · 2024: 10 · 2023: 15 · 2022: 16 · 2021: 18 · 2020: 16 · 2019: 12 · 2018: 14 · 2017: 21 · 2016: 32 · 2015: 30 · 2014: 36 · 2013: 47 · 2012: 43
FWCI: 8.21
Type: journal article
Language: en
Open access: closed
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
Locations: Journal of Allergy and Clinical Immunology (publishedVersion)
PubMed (publishedVersion)
Topics: Health Sciences › Medicine › Immunology and Allergy › Food Allergy and Anaphylaxis Research
Health Sciences › Medicine › Pharmacology (medical) › Drug-Induced Adverse Reactions
Health Sciences › Medicine › Gastroenterology › Eosinophilic Esophagitis
Keywords: food allergy, IgE-mediated allergy, non-IgE-mediated allergy, oral tolerance, food allergens, cow's milk allergy, egg allergy, peanut allergy, tree nuts, fish allergy, shellfish allergy, food allergy diagnosis, elimination diet, oral food challenge, allergen characterization, immunopathogenesis, food allergy management, accidental ingestion
MeSH terms: Adult, Allergens, Anaphylaxis, Child, Child, Preschool, Diagnosis, Differential, Dietary Proteins, Food Hypersensitivity, Gastrointestinal Diseases, Humans, Infant, Patient Education as Topic, Anti-Asthmatic Agents

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