Agents causing occupational asthma
Abstract
The workplace is a significant contributor to the burden of asthma. Although the majority of cases probably represent what is labeled work-exacerbated asthma, in a significant number of subjects, asthma is actually caused by 1 or more agents present in the workplace; this is occupational asthma. Two types of occupational asthma are distinguished, according to whether the asthma appears after a latency period. This article discusses (1) two types of agents causing asthma with a latency period and acting through an apparently immunologic mechanism (high-molecular-weight agents and low-molecular-weight agents) and (2) agents causing asthma without a latency period.
Integrity signals
Registry
Cites
Statistics
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
Over 250 agents may potentially cause sensitization and possibly occupational asthma.
“Over 250 agents may potentially cause sensitization and possibly occupational asthma (OA), and comprehensive lists are available (Table 1) (112–115).”
From Epidemiology of Asthma in Children and Adults (2019) · cites this paper as [114]
Cites
Reactive Airways Dysfunction Syndrome (RADS)
Brooks, S. M., Weiss, M. A., & Bernstein, I. L. (1985) · Chest · doi:10.1378/chest.88.3.376 · Cited by 678 · see citing works
Reactive Airways Dysfunction Syndrome (RADS)
Templeton, D. M., Schwenk, M., Klein, R., & Duffus, J. H. (2016) · IUPAC Standards Online · doi:10.1515/iupac.84.1097 · Cited by 573 · see citing works
Kogevinas, M., Zock, J., Jarvis, D., Kromhout, H., Lillienberg, L., Plana, E., Radon, K., Torén, K., Alliksoo, A., Benke, G., et al. (2007) · The Lancet · doi:10.1016/s0140-6736(07)61164-7 · Cited by 410 · see citing works
Malo, J., Chan‐Yeung, M., & Bernstein, D. I. (1993) · Cited by 395 · see citing works
How much adult asthma can be attributed to occupational factors?
Blanc, P. D., & Toren, K. (1999) · The American Journal of Medicine · doi:10.1016/s0002-9343(99)00307-1 · Cited by 295 · see citing works
Community Outbreaks of Asthma Associated with Inhalation of Soybean Dust
Antó, J. M., Sunyer, J., Rodriguez‐Roisin, R., Suarez-Cervera, M., & Vazquez, L. (1989) · New England Journal of Medicine · doi:10.1056/nejm198904273201701 · Cited by 283 · see citing works
Prevalence of Occupational Asthma Due to Latex among Hospital Personnel
Vandenplas, O., Delwiche, J. P., Evrard, G., Aimont, P., van der Brempt, X., Jamart, J., & Delaunois, L. (1995) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.151.1.7812572 · Cited by 250 · see citing works
Medina-Ramón, M., Zock, J. P., Kogevinas, M., Sunyer, J., Torralba, Y., Borrell, A., Burgos, F., & Antó, J. M. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.017640 · Cited by 238 · see citing works
Occupational asthma in snow crab-processing workers
Cartier, A., Malo, J., Forest, F., Lafrance, M., Pineau, L., St-Aubin, J. J., & Dubois, J. Y. (1984) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(84)90256-2 · Cited by 215 · see citing works
Mapp, C. E., Fryer, A. A., Marzo, N. D., Pozzato, V., Padoan, M., Boschetto, P., Strange, R. C., Hemmingsen, A., & Spiteri, M. A. (2002) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2002.123234 · Cited by 204 · see citing works
Venables, K. M., Topping, M. D., Howe, W., Luczynska, C. M., Hawkins, R., & Taylor, A. J. N. (1985) · BMJ · doi:10.1136/bmj.290.6463.201 · Cited by 200 · see citing works
Jarvis, J. E., Seed, M., Elton, R. A., Sawyer, L., & Agius, R. M. (2005) · Occupational and Environmental Medicine · doi:10.1136/oem.2004.016402 · Cited by 184 · see citing works
Houba, R., Heederik, D. J. J., & Doekes, G. (1998) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.158.5.9803055 · Cited by 163 · see citing works
Incidence and Determinants of IgE-mediated Sensitization in Apprentices
Gautrin, D., Ghezzo, H., Infante‐Rivard, C., & Malo, J. (2000) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/ajrccm.162.4.2001023 · Cited by 134 · see citing works
Juniper, C. P., How, M. J., Goodwin, B. F. J., & KINSHOTT, A. K. (1977) · Occupational Medicine · doi:10.1093/occmed/27.1.3 · Cited by 109 · see citing works
Epidemiological Approaches in Occupational Asthma
Becklake, M. R. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-4 · Cited by 108 · see citing works
Aluminium potroom asthma: the Norwegian experience
Kongerud, J. S., Boe, J., Søyseth, V., Naalsund, A., & Magnus, P. M. (1994) · European Respiratory Journal · doi:10.1183/09031936.94.07010165 · Cited by 87 · see citing works
Long-Term Outcomes in a Prospective Cohort of Apprentices Exposed to High-Molecular-Weight Agents
Gautrin, D., Ghezzo, H., Infante‐Rivard, C., Magnan, M., L’Archevêque, J., Suarthana, E., & Malo, J. (2008) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.200707-991oc · Cited by 79 · see citing works
Piipari, R., & Keskinen, H. (2005) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2005.02386.x · Cited by 75 · see citing works
Merget, R., Caspari, C., Dierkes-Globisch, A., Kulzer, R., Breitstadt, R., Kniffka, A., Degens, P. O., & Schultze‐Werninghaus, G. (2001) · Journal of Allergy and Clinical Immunology · doi:10.1067/mai.2001.113564 · Cited by 73 · see citing works
Incidence and host determinants of work‐related rhinoconjunctivitis in apprentice pastry‐makers
Gautrin, D., Ghezzo, H., Infante‐Rivard, C., & Malo, J. (2002) · Allergy · doi:10.1034/j.1398-9995.2002.23636.x · Cited by 70 · see citing works
Occupational asthma in a factory making flux-cored solder containing colophony.
Burge, P. S., Edge, G., Hawkins, R., White, V., & Taylor, A. J. N. (1981) · Thorax · doi:10.1136/thx.36.11.828 · Cited by 70 · see citing works
World at work: Fish processing workers
Jeebhay, M. F., Robins, T. G., & Lopata, A. L. (2004) · Occupational and Environmental Medicine · doi:10.1136/oem.2002.001099 · Cited by 66 · see citing works
Immunology and immunopathology of trimellitic anhydride pulmonary reactions
Patterson, R., Zeiss, C. R., & Pruzansky, J. J. (1982) · Journal of Allergy and Clinical Immunology · doi:10.1016/0091-6749(82)90196-8 · Cited by 60 · see citing works
Occupational asthma in greenhouse workers
Mons, E. (2004) · Current Opinion in Pulmonary Medicine · doi:10.1097/00063198-200403000-00010 · Cited by 60 · see citing works
Gender and snow crab occupational asthma in Newfoundland and Labrador, Canada
Howse, D., Gautrin, D., Neis, B., Cartier, A., Horth-Susin, L., Jong, M., & Swanson, M. C. (2005) · Environmental Research · doi:10.1016/j.envres.2005.06.008 · Cited by 55 · see citing works
Henneberger, P. K. (2007) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e328054c640 · Cited by 55 · see citing works
Prevention of occupational asthma—practical implications for occupational physicians
Tarlo, S. M., & Liss, G. M. (2005) · Occupational Medicine · doi:10.1093/occmed/kqi182 · Cited by 43 · see citing works
Reactive Airways Dysfunction Syndrome (RADS) and Irritant-Induced Asthma
Brooks, S. M. (2013) · Springer eBooks · doi:10.1007/978-1-4614-9044-9_3 · Cited by 40 · see citing works
Reactive Airways Dysfunction Syndrome and Irritant-Induced Asthma
Gautrin, D., Brooks, S. M., & Henneberger, P. K. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-26 · Cited by 36 · see citing works
8 Occupational Allergy due to Platinum Complex Salts
Pepys, J. (1984) · Clinics in Immunology and Allergy · doi:10.1016/s0260-4639(22)00249-3 · Cited by 31 · see citing works
Vandenplas, O., Beezhold, D. H., & Tarlo, S. M. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-20 · Cited by 17 · see citing works
Historical Aspects of Occupational Asthma
Pepys, J., Bernstein, I. L., Malo, J., & Tarlo, S. M. (2021) · CRC Press eBooks · doi:10.1201/9781003000624-2 · Cited by 16 · see citing works
Western Red Cedar (Thuja plicata) and Other Wood Dusts
Chan‐Yeung, M., & Malo, J. (2006) · Cited by 13 · see citing works
Hypersensitivity Pneumonitis and Organic Dust Toxic Syndromes
Cormier, Y. F., & Schuyler, M. R. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-30 · Cited by 11 · see citing works
Laboratory Animal, Insect, Fish and Shellfish Allergy
Gordon, S., Bush, R., & Taylor, A. J. N. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-19 · Cited by 9 · see citing works
Acute Airway Diseases Due to Organic Dust Exposure
Bernstein, L., Essen, S. V., Singh, J., & Schwartz, D. A. (2006) · CRC Press eBooks · doi:10.3109/9780849374531-28 · Cited by 2 · see citing works
Flagged first, then by citations
3 of the 40 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
Epidemiology of Asthma in Children and Adults
Dharmage, S. C., Perret, J. L., & Custovic, A. (2019) · Frontiers in Pediatrics · doi:10.3389/fped.2019.00246 · Cited by 1,200 · see citing works
“- Work exacerbated (pre-existing) asthma (113, 114) (113, 114)”
Hsu, N., Lee, C., Wang, J., Li, Y.-C., Chang, H.-W., Chen, C., Bornehag, C., Wu, P., Sundell, J., & Su, H.-J. J. (2011) · Indoor Air · doi:10.1111/j.1600-0668.2011.00753.x · Cited by 207 · see citing works
Quirce, S., & Barranco, P. (2010) · PubMed · Cited by 182 · see citing works
Quinn, M., Henneberger, P. K., Braun, B. I., Delclos, G. L., Fagan, K., Huang, V., Knaack, J. S., Kusek, L., Lee, S., Moual, N. L., et al. (2015) · American Journal of Infection Control · doi:10.1016/j.ajic.2015.01.029 · Cited by 181 · see citing works
Zock, J., Vizcaya, D., & Moual, N. L. (2010) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e32833733fe · Cited by 160 · see citing works
EAACI position paper: irritant‐induced asthma
Vandenplas, O., Wiszniewska, M., Raulf, M., Frederic de, B. L. A. Y., van Wijk, R. G., Moscato, G., Nemery, B., Pala, G., Quirce, S., Sastre, J., et al. (2014) · Allergy · doi:10.1111/all.12448 · Cited by 151 · see citing works
Wheat allergens associated with Baker's asthma.
Salcedo, G., Quirce, S., & Díaz‐Perales, A. (2011) · PubMed · Cited by 148 · see citing works
Asthma and Chronic Obstructive Pulmonary Disease: Common Genes, Common Environments?
Postma, D. S., Kerkhof, M., Boezen, H. M., & Koppelman, G. H. (2011) · American Journal of Respiratory and Critical Care Medicine · doi:10.1164/rccm.201011-1796pp · Cited by 133 · see citing works
“Environmental exposures in adulthood Occupational exposures (75) Occupational exposures (13)”
BackgroundBronchial asthma and COPD due to irritants in the workplace - an evidence-based approach
Baur, X., Bakehe, P., & Vellguth, H. (2012) · Journal of Occupational Medicine and Toxicology · doi:10.1186/1745-6673-7-19 · Cited by 112 · see citing works
“Occupational COPD has not been considered as a subgroup of COPD thus so far [559,564]; and the definition of irritant-induced OA has been heterogenous at best [24,552,565,566].”
BackgroundDiagnosis and Management of Grain-Induced Asthma
Quirce, S., & Díaz‐Perales, A. (2013) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2013.5.6.348 · Cited by 94 · see citing works
“Asthma caused by allergy to proteins from cereal grains is one of the most common types of occupational asthma (OA) and its prevalence does not seem to be declining.(1) The main professions affected are: bakers, confectioners, pastry factory workers, millers, farmers, and cereal handlers.”
BackgroundChemical and biological work-related risks across occupations in Europe: a review
Montaño, D. (2014) · Journal of Occupational Medicine and Toxicology · doi:10.1186/1745-6673-9-28 · Cited by 92 · see citing works
“high-molecular-weight > 5 kDa), (iii) the duration of exposure and the agent concentration [57,58].”
BackgroundAllergens causing occupational asthma: an evidence-based evaluation of the literature
Baur, X., & Bakehe, P. (2014) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-013-0866-9 · Cited by 90 · see citing works
“We also screened the reference lists of already published reviews including their references (van Kampen et al. 2000; Bernstein et al. 2006; Baur 2008; Malo and Chan-Yeung 2009; Tarlo and Malo 2009; Quirce and Sastre 2011).”
MethodLei, T., Chen, F., Liu, H., Sun, H., Kang, Y., Li, D., Li, Y., & Hou, T. (2017) · Molecular Pharmaceutics · doi:10.1021/acs.molpharmaceut.7b00317 · Cited by 84 · see citing works
Occupational Exposure and New-onset Asthma in a Population-based Study in Northern Europe (RHINE)
Lillienberg, L., Andersson, E., Janson, C., Dahlman‐Höglund, A., Forsberg, B., Holm, M., Gĺslason, T., Jögi, R., Omenaas, E. R., Schlünssen, V., et al. (2012) · The Annals of Occupational Hygiene · doi:10.1093/annhyg/mes083 · Cited by 80 · see citing works
“…under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. doi:10.1093/annhyg/mes083 482”
BackgroundInfluentialA compendium of causative agents of occupational asthma
Baur, X. (2013) · Journal of Occupational Medicine and Toxicology · doi:10.1186/1745-6673-8-15 · Cited by 79 · see citing works
“Previous reports and reviews have accumulated narrative and experimental evidence for about 300 causative agents, which are often divided into high or low molecular weight groups ([21-28]).”
BackgroundAssessment of immunotoxicity induced by chemicals in human precision-cut lung slices (PCLS)
Lauenstein, L., Switalla, S., Prenzler, F., Seehase, S., Pfennig, O., Förster, C., Fieguth, H., Braun, A. C., & Sewald, K. (2014) · Toxicology in Vitro · doi:10.1016/j.tiv.2013.12.016 · Cited by 78 · see citing works
“Due to increasing incidences of OA induced by LMW agents, the imperative emerged to identify LMW chemicals which could trigger a sensitization at workplaces, in particular with regard to risk assessment (Malo and Chan-Yeung, 2009; Orriols et al., 2006).”
BackgroundDefinitions and Classification of Work-Related Asthma
Malo, J., & Vandenplas, O. (2011) · Immunology and Allergy Clinics of North America · doi:10.1016/j.iac.2011.07.003 · Cited by 75 · see citing works
Component-Resolved Diagnosis in Food Allergies
Calamelli, E., Liotti, L., Beghetti, I., Piccinno, V., Serra, L., & Bottau, P. (2019) · Medicina · doi:10.3390/medicina55080498 · Cited by 70 · see citing works
Under-estimation of self-reported occupational exposure by questionnaire in hospital workers
Donnay, C., Denis, M.-A., Magis, R., Févotte, J., Massin, N., Dumas, O., Pin, I., Choudat, D., Kauffmann, F., & Moual, N. L. (2011) · Occupational and Environmental Medicine · doi:10.1136/oem.2010.061671 · Cited by 67 · see citing works
“Healthcare workers may be exposed to high levels of a number of pollutants (cleaning and sterilising products, aerosolised medications) and to sensitisers in particular (latex, surface disinfectants, biocides).(5) Disinfecting and cleaning products, such as bleach/ chlorine and ammonia, are skin, nose and lung irritan…”
BackgroundProgress in Occupational Asthma
Tiotiu, A. I., Novakova, S. M., Labor, M., Emelyanov, A. V., Mihaicuta, S. D., Novakova, P. I., & Nedeva, D. (2020) · International Journal of Environmental Research and Public Health · doi:10.3390/ijerph17124553 · Cited by 67 · see citing works
“Wheat is the most frequently encountered cereal, but soya is highly allergenic and thus often the causative agent [15,16].”
BackgroundSmith, B., Wong, C. A., Boyko, E. J., Phillips, C. J., Gackstetter, G. D., Ryan, M. A. K., & Smith, T. C. (2012) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e31825107f9 · Cited by 65 · see citing works
Zhu, H., Zhang, H., Lü, K., Yang, S., Tang, X., Zhou, M., Sun, G., Zhang, Z., & Chu, H. (2022) · Environmental Science & Technology · doi:10.1021/acs.est.2c05357 · Cited by 53 · see citing works
Pesonen, M., Koskela, K., & Aalto‐Korte, K. (2020) · Contact Dermatitis · doi:10.1111/cod.13547 · Cited by 50 · see citing works
Jiang, J., Ding, X., Isaacson, K. P., Tasoglou, A., Huber, H., Shah, A. D., Jung, N., & Boor, B. E. (2021) · Journal of Hazardous Materials Letters · doi:10.1016/j.hazl.2021.100042 · Cited by 48 · see citing works
Work related asthma. A causal analysis controlling the healthy worker effect
Dumas, O., Moual, N. L., Siroux, V., Heederik, D. J. J., García‐Aymerich, J., Varraso, R., Kauffmann, F., & Basagaña, X. (2013) · Occupational and Environmental Medicine · doi:10.1136/oemed-2013-101362 · Cited by 48 · see citing works
Pro/Con debate: is occupational asthma induced by isocyanates an immunoglobulin E‐mediated disease?
Wisnewski, A. V., & Jones, M. (2010) · Clinical & Experimental Allergy · doi:10.1111/j.1365-2222.2010.03550.x · Cited by 48 · see citing works
Neuro-immune interactions in chemical-induced airway hyperreactivity
Devos, F. C., Boonen, B., Alpizar, Y. A., Maes, T., Hox, V., Seys, S., Pollaris, L., Liston, A., Nemery, B., Talavera, K., et al. (2016) · European Respiratory Journal · doi:10.1183/13993003.01778-2015 · Cited by 44 · see citing works
Combined exposure to heavy metals in PM2.5 and pediatric asthma
Hsieh, C.-Y., Jung, C., Lin, C., & Hwang, B. (2020) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2020.12.634 · Cited by 44 · see citing works
Time trends in occupational asthma in Belgium
Vandenplas, O., Lantin, A.-C., D’Alpaos, V., Larbanois, A., Hoet, P., Vandeweerdt, M., Thimpont, J., & Speybroeck, N. (2011) · Respiratory Medicine · doi:10.1016/j.rmed.2011.05.002 · Cited by 43 · see citing works
Molecular Signature of Asthma-Enhanced Sensitivity to CuO Nanoparticle Aerosols from 3D Cell Model
Kooter, I. M., Ilves, M., Gröllers‐Mulderij, M., Duistermaat, E., Tromp, P., Kuper, C. F., Kinaret, P., Savolainen, K., Greco, D., Karisola, P., et al. (2019) · ACS Nano · doi:10.1021/acsnano.9b01823 · Cited by 43 · see citing works
Uváčková, Ľ., Škultéty, Ľ., Bekešová, S., McClain, S., & Hajdúch, M. (2013) · Journal of Proteome Research · doi:10.1021/pr400336f · Cited by 42 · see citing works
Prevalence of asthma by industry and occupation in the U.S. working population
McHugh, M. K., Symanski, E., Pompeii, L. A., & Delclos, G. L. (2010) · American Journal of Industrial Medicine · doi:10.1002/ajim.20800 · Cited by 34 · see citing works
Budnik, L. T., Preisser, A. M., Permentier, H. P., & Baur, X. (2012) · International Archives of Occupational and Environmental Health · doi:10.1007/s00420-012-0772-6 · Cited by 32 · see citing works
“Asthma is generally acknowledged as a critical endpoint after exposure to isocyanates (Malo and Chan-Yeung 2009; Maestrelli et al. 2009; Mapp et al. 1994), like 4,4 0 -methy- lenediphenyl diisocyanate (MDI) the most commonly used isocyanate.”
BackgroundOccupational irritants and asthma: an Estonian cross-sectional study of 34 000 adults
Dumas, O., Laurent, É., Bousquet, J. J., Metspalu, A., Milani, L. A., Kauffmann, F., & Moual, N. L. (2014) · European Respiratory Journal · doi:10.1183/09031936.00172213 · Cited by 30 · see citing works
“[5, 7] IgE-mediated mechanisms have been proven for most high and some low molecular weight agents.”
BackgroundResultSadekar, N., Boislève, F., Dekant, W., Fryer, A. D., Gerberick, G. F., Griem, P., Hickey, C., Krutz, N. L., Lemke, O., Mignatelli, C., et al. (2021) · Critical Reviews in Toxicology · doi:10.1080/10408444.2021.2024142 · Cited by 29 · see citing works
“Depending on the chemical and its exposure, symptoms can additionally be classified as immediate or late-onset (Malo and Chan-Yeung 2009).”
BackgroundB-lymphocytes as Key Players in Chemical-Induced Asthma
Vooght, V. D., Carlier, V. A., Devos, F. C., Haenen, S., Verbeken, E. K., Nemery, B., Hoet, P., & Vanoirbeek, J. A. (2013) · PLoS ONE · doi:10.1371/journal.pone.0083228 · Cited by 28 · see citing works
“In low molecular weight induced asthma, specific IgE antibodies are frequently not present, which suggests that non-IgE mediated mechanisms are involved in the pathogenesis [5].”
BackgroundLaKind, J. S., & Goodman, M. G. (2019) · Allergy Asthma and Clinical Immunology · doi:10.1186/s13223-019-0384-8 · Cited by 28 · see citing works
Cleaning and asthma characteristics in women
Dumas, O., Siroux, V., Luu, F., Nadif, R., Zock, J., Kauffmann, F., & Moual, N. L. (2013) · American Journal of Industrial Medicine · doi:10.1002/ajim.22244 · Cited by 28 · see citing works
“, 2012], there is a general agreement that occupational asthma may be induced through immunologic or nonimmunologic mechanisms [Maestrelli et al., 2009; Malo and Chan-Yeung, 2009], related to different types of occupational exposures (allergens or irritants).”
BackgroundOccupational Asthma: New Low-Molecular-Weight Causal Agents, 2000–2010
Pralong, J. A., Cartier, A., Vandenplas, O., & Labrecque, M. (2012) · Journal of Allergy · doi:10.1155/2012/597306 · Cited by 27 · see citing works
“More than 400 distinct agents have been documented as causing OA [10], and their number is steadily growing with the development of industrial processes.”
Farm Work-Related Asthma Among US Primary Farm Operators
Mazurek, J. M., White, G. E., Rodman, C. M., & Schleiff, P. L. (2015) · Journal of Agromedicine · doi:10.1080/1059924x.2014.976729 · Cited by 26 · see citing works
Knaysi, G. A., Smith, A. R., Wilson, J. M., & Wiśniewski, J. (2017) · Current Allergy and Asthma Reports · doi:10.1007/s11882-017-0675-4 · Cited by 26 · see citing works
“subtilis is a known sensitizing agent linked to occupational asthma [32].”
BackgroundBello, A., Xue, Y., Gore, R. J., Woskie, S., & Bello, D. (2019) · International Journal of Hygiene and Environmental Health · doi:10.1016/j.ijheh.2019.04.014 · Cited by 24 · see citing works
Understanding health beliefs and behaviour in workers with suspected occupational asthma
Walters, G. I., Soundy, A., Robertson, A. S., Burge, P. S., & Ayres, J. G. (2015) · Respiratory Medicine · doi:10.1016/j.rmed.2015.01.003 · Cited by 23 · see citing works
“Most cases of occupational asthma have an allergic mechanism, where there is sensitization to an agent after a latent period of exposure [2].”
New causes of occupational asthma
Quirce, S., & Sastre, J. (2011) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e328344586a · Cited by 22 · see citing works
Hoy, R. F., BURDON, J. G. W., Chen, L., Miles, S., Perret, J. L., Prasad, S., Radhakrishna, N., Rimmer, J., Sim, M. R., Yates, D. H., et al. (2020) · Respirology · doi:10.1111/resp.13951 · Cited by 21 · see citing works
Lemière, C., Ameille, J., Boschetto, P., Labrecque, M., & Pralong, J.-A. (2012) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2012.06.003 · Cited by 21 · see citing works
Weinmann, T., Forster, F., von Mutius, E., Vogelberg, C., Genuneit, J., Windstetter, D., Nowak, D., Radon, K., & Gerlich, J. (2019) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0000000000001655 · Cited by 21 · see citing works
Lalko, J., Kimber, I., Dearman, R. J., Api, A. M., & Gerberick, G. F. (2012) · Journal of Immunotoxicology · doi:10.3109/1547691x.2012.725784 · Cited by 21 · see citing works
“This includes several commonly cited and well-described classes of materials such as the acid anhydrides, diisocyanates, reactive dyes, and platinum salts (Malo and Chan-Yeung, 2009).”
BackgroundCleaning agents and disinfectants: moving from recognition to action and prevention
Heederik, D. J. J. (2014) · Clinical & Experimental Allergy · doi:10.1111/cea.12286 · Cited by 20 · see citing works
“Many disinfectants and cleaning agents are known as irritants or sensitisers [13].”
Asthma phenotypes in adults and clinical implications
Fajt, M. L., & Wenzel, S. E. (2009) · Expert Review of Respiratory Medicine · doi:10.1586/ers.09.57 · Cited by 19 · see citing works
Specificity of α‐amylase and trypsin inhibitor proteins in wheat against insect pests
Priya, S., Kumar, S., Kaur, N., & Gupta, A. (2012) · New Zealand Journal of Crop and Horticultural Science · doi:10.1080/01140671.2012.722112 · Cited by 18 · see citing works
“The association between inhibitors and allergies is of greatest concern, as baker’s asthma is one of the most common types of occupational asthma and its prevalence does not appear to be declining (Malo & Chan-Yeung 2009).”
BackgroundCells and mediators in diisocyanate-induced occupational asthma
Shin, Y. S., Kim, M. A., Pham, D. L., & Park, H. (2013) · Current Opinion in Allergy and Clinical Immunology · doi:10.1097/aci.0b013e32835e0322 · Cited by 18 · see citing works
Qaid, E. Y. A., & Long, I. (2025) · Egyptian Journal of Bronchology · doi:10.1186/s43168-025-00443-w · Cited by 16 · see citing works
“Ammonia and chlorine are two examples of compounds that can quickly cause irritant-induced asthma [2, 15].”
InfluentialTsui, H.-C., Ronsmans, S., Hoet, P., Nemery, B., & Vanoirbeek, J. (2022) · The Journal of Allergy and Clinical Immunology In Practice · doi:10.1016/j.jaip.2022.05.014 · Cited by 16 · see citing works
Talini, D., Novelli, F., Bacci, E., Dente, F. L., Santis, M. D., Franco, A. D., Melosini, L., Vagaggini, B., & Paggiaro, P. L. (2011) · Journal of Allergy · doi:10.1155/2011/781470 · Cited by 15 · see citing works
“Occupational asthma with latency period can be induced by sensitization to either a specific allergen (high molecular weight compounds, HMWC) or chemical compounds (low molecular weight compounds, LMWC) present in the workplace [1].”
BackgroundVooght, V. D., Haenen, S., Verbeken, E. K., Nemery, B., Hoet, P., & Vanoirbeek, J. A. (2010) · Toxicology · doi:10.1016/j.tox.2010.09.014 · Cited by 15 · see citing works
Bonavigo, L., Salve, M. D., Zucchetti, M., & Annunziata, D. (2009) · Progress in Nuclear Energy · doi:10.1016/j.pnucene.2009.07.009 · Cited by 13 · see citing works
“The resulting metal dusts can be inhaled; this inhalation per se produces damage; moreover it causes pathologies like respiratory syndrome or chromosome damage (Gurzau et al., 2003; Jelmert et al., 1994; Malo and Chan-Yeung, 2009; Rana, 2008).”
BackgroundCasas, L., & Nemery, B. (2014) · European Respiratory Journal · doi:10.1183/09031936.00090014 · Cited by 13 · see citing works
Advances in environmental and occupational respiratory disease in 2007
Bush, R. K., & Peden, D. B. (2008) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2008.03.034 · Cited by 12 · see citing works
de Olim, C., Bégin, D., Boulet, L., Cartier, A., Gérin, M., & Lemière, C. (2015) · Canadian Respiratory Journal · doi:10.1155/2015/519123 · Cited by 12 · see citing works
“Workers from many industries are typically not exposed to a single sensitizing agent, but to several agents (13).”
BackgroundOccupational Exposures and the Development of New-onset Asthma
Hoy, R. F., Burgess, J. A., Benke, G., Matheson, M. C., Morrison, S. C., Gurrin, L. C., Walters, E. H., Dharmage, S. C., & Abramson, M. J. (2013) · Journal of Occupational and Environmental Medicine · doi:10.1097/jom.0b013e31827edefb · Cited by 12 · see citing works
Espinosa, A., Zock, J., Benavente, Y., Boffetta, P., Becker, N., Brennan, P., Cocco, P., Foretová, L., Maynadié, M., Staines, A. S., et al. (2013) · Cancer Epidemiology · doi:10.1016/j.canep.2013.02.006 · Cited by 11 · see citing works
Occupational exposure to toluene diisocyanate and neutrophilic bronchitis without asthma
Pala, G., Pignatti, P., & Moscato, G. (2011) · Clinical Toxicology · doi:10.3109/15563650.2011.590141 · Cited by 11 · see citing works
Japanese guidelines for occupational allergic diseases 2020
Dobashi, K., Usami, A., Yokozeki, H., Tsurikisawa, N., Nakamura, Y., Sato, K., Okumura, J., Yamaguchi, M., Dobashi, K., Akiyama, K., et al. (2020) · Allergology International · doi:10.1016/j.alit.2020.03.010 · Cited by 11 · see citing works
Employed adults with asthma who have frequent workplace exposures
White, G. E., Mazurek, J. M., & Storey, E. P. (2014) · Journal of Asthma · doi:10.3109/02770903.2014.944984 · Cited by 11 · see citing works
“Adult asthma is associated with a large number of agents, including over 350 that can be found in the workplace [5].”
Olivieri, M., Spiteri, G., Brandi, J., Cecconi, D., Fusi, M., Zanoni, G., & Rizzi, C. (2022) · Molecules · doi:10.3390/molecules27041212 · Cited by 10 · see citing works
Immunological Treatments for Occupational Allergy
Crivellaro, M., Senna, G., Marcer, G., & Passalacqua, G. (2013) · International Journal of Immunopathology and Pharmacology · doi:10.1177/039463201302600301 · Cited by 10 · see citing works
Japanese Guideline for Occupational Allergic Diseases 2014
Dobashi, K., Akiyama, K., Usami, A., Yokozeki, H., Ikezawa, Z., Tsurikisawa, N., Nakamura, Y., Sato, K., & Okumura, J. (2014) · Allergology International · doi:10.2332/allergolint.14-rai-0771 · Cited by 10 · see citing works
Scholten, B., Westerhout, J., Pronk, A., Stierum, R. H., Vlaanderen, J. J., Vermeulen, R. C. H., Jones, K., Santonen, T., & Portengen, L. (2023) · Environment International · doi:10.1016/j.envint.2023.107917 · Cited by 9 · see citing works
Japanese guidelines for occupational allergic diseases 2017
Dobashi, K., Akiyama, K., Usami, A., Yokozeki, H., Ikezawa, Z., Tsurikisawa, N., Nakamura, Y., Sato, K., Okumura, J., & Takayama, K. (2017) · Allergology International · doi:10.1016/j.alit.2016.12.010 · Cited by 9 · see citing works
“a) PUVA [A] b) NB-UVB [B] (5) Barrier-cream gloves are effective for prevention.”
Pralong, J. A., Seed, M., Yasri, R., Agius, R. M., Cartier, A., & Labrecque, M. (2012) · Occupational and Environmental Medicine · doi:10.1136/oemed-2012-101189 · Cited by 8 · see citing works
Respiratory symptoms of exposure to substances in the workplace among Bulgarian dentists
Stoeva, I. (2020) · Community Dentistry And Oral Epidemiology · doi:10.1111/cdoe.12584 · Cited by 8 · see citing works
Word, L. J., McAden, E. P., Poole, C., & Nylander‐French, L. A. (2022) · Frontiers in Genetics · doi:10.3389/fgene.2022.944197 · Cited by 8 · see citing works
Asthme et expositions aux produits de nettoyage
Dumas, O., Kauffmann, F., & Moual, N. L. (2013) · Archives des maladies professionnelles et de médecine du travail/Archives des maladies professionnelles et de l'environnement · doi:10.1016/j.admp.2012.12.014 · Cited by 8 · see citing works
Occupational asthma caused by inhaling smoke from roasting perilla seeds
Jung, S., Lee, W., Yong, S. J., Shin, K. C., Kim, C. W., Lee, J.-H., Jung, Y.-R., Kim, H. S., Yu, T.-S., & Kim, S. (2013) · Allergy Asthma & Respiratory Disease · doi:10.4168/aard.2013.1.1.90 · Cited by 8 · see citing works
Association of MBL With Work-Related Respiratory Symptoms in Bakery Workers
Kim, M., Yoon, M. K., Kim, S., & Park, H. (2016) · Allergy Asthma and Immunology Research · doi:10.4168/aair.2017.9.1.85 · Cited by 7 · see citing works
“Baker’s asthma is the most common occupational asthma and wheat is the representative cereal causing grain-induced asthma.(1-5) IgE-mediated sensitization is known as the major mechanism of baker’s asthma.”
BackgroundAdvances in environmental and occupational respiratory diseases in 2009
Peden, D. B., & Bush, R. K. (2010) · Journal of Allergy and Clinical Immunology · doi:10.1016/j.jaci.2010.01.004 · Cited by 7 · see citing works
Word, L. J., French, J. E., Robbins, Z. G., & Nylander‐French, L. A. (2021) · Frontiers in Genetics · doi:10.3389/fgene.2021.700636 · Cited by 7 · see citing works
Facteurs déclenchants : allergènes respiratoires (usuels et professionnels)
Barnig, C., & Casset, A. (2012) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2012.04.004 · Cited by 7 · see citing works
Bittner, C., Garrido, M. V., Harth, V., & Preisser, A. M. (2016) · Advances in experimental medicine and biology · doi:10.1007/5584_2016_226 · Cited by 7 · see citing works
Occupation held at the time of asthma symptom development
Knoeller, G. E., Mazurek, J. M., & Storey, E. P. (2013) · American Journal of Industrial Medicine · doi:10.1002/ajim.22203 · Cited by 6 · see citing works
Knowledge and Perceptions of Asthma in a Nigerian High School
Ilesanmi, O. T. (2017) · Texila international journal of public health · doi:10.21522/tijph.2013.05.04.art058 · Cited by 6 · see citing works
Orphan immunotherapies for allergic diseases
Ridolo, E., Montagni, M., Incorvaia, C., Senna, G., & Passalacqua, G. (2016) · Annals of Allergy Asthma & Immunology · doi:10.1016/j.anai.2015.12.031 · Cited by 6 · see citing works
Word, L. J., French, J. E., Robbins, Z. G., Boyer, J. C., & Nylander‐French, L. A. (2020) · Frontiers in Genetics · doi:10.3389/fgene.2020.00836 · Cited by 6 · see citing works
Respiratory symptoms of exposure to substances in the workplace among dental laboratory technicians
Stoeva, I. (2020) · Medycyna Pracy · doi:10.13075/mp.5893.01033 · Cited by 6 · see citing works
Inhalationsbedingte chemische Lungenschädigung
Ochmann, U., & Nowak, D. (2009) · Der Pneumologe · doi:10.1007/s10405-008-0229-5 · Cited by 6 · see citing works
Asthma and COPD: Common Genes, Common Environments?
Postma, D. S., Kerkhof, M., Boezen, H. M., & Koppelman, G. H. (2011) · Cited by 5 · see citing works
Component-resolved Diagnostics in Allergy Practice Focusing on Food Allergy: A Systematic Review
Moitra, S., Tripathi, S. K., Mukherjee, S., Samajdar, S. S., Ghosh, S., Munshi, S., & Vedanthan, P. K. (2023) · Bengal Physician Journal · doi:10.5005/jp-journals-10070-8016 · Cited by 5 · see citing works
Prevalence and Risk Factors of Work-Related Asthma in Hospital Cleaning Workers
Ecin, S. M., Sandal, A., Çetintepe, S. P., Koyuncu, A., Kurt, Ö. K., Yıldız, A. N., & Demır, A. U. (2022) · Turkish Thoracic Journal · doi:10.5152/turkthoracj.2022.21183 · Cited by 5 · see citing works
Berufliche Rhinitis und Asthma
Scherer, K., Bircher, Tamm, M., & Miedinger (2012) · Therapeutische Umschau · doi:10.1024/0040-5930/a000283 · Cited by 5 · see citing works
“tionszwischenfall) Asthma ausgelöst wird [3].”
Asthme professionnel indemnisé dans le centre tunisien: étude transversale sur huit ans
Omrane, A., Kreim, A., Henchi, M. A., Kammoun, S., Bessadi, L., Amri, C., Khalfallh, T., & Bouzgarrou, L. (2017) · Pan African Medical Journal · doi:10.11604/pamj.2017.26.164.11486 · Cited by 5 · see citing works
“Si différents mécanismes physiopathologiques peuvent être incriminés dans le développement de cette pathologie, l’asthme allergique demeure le mieux étudié [2, 3].”
Primary Care of the Patient with Asthma
Lenaeus, M. J., & Hirschmann, J. V. (2015) · Medical Clinics of North America · doi:10.1016/j.mcna.2015.05.007 · Cited by 5 · see citing works
Moscato, G., Dykewicz, M. S., Desrosiers, M., & Castano, R. (2013) · Asthma in the Workplace · doi:10.3109/9781841849256.024 · Cited by 4 · see citing works
Asthma in damp indoor work environments
Karvala, K. (2012) · Työväentutkimus Vuosikirja · Cited by 4 · see citing works
Oh, S.-M., & Kwon, E.-J. (2011) · The Journal of the Korea Contents Association · doi:10.5392/jkca.2011.11.10.355 · Cited by 3 · see citing works
Trends in occupational respiratory conditions with short latency in the UK
Barradas, A. M. C., Iskandar, I. Y. K., Carder, M., Gittins, M., Fishwick, D., Seed, M., & van Tongeren, M. (2024) · Occupational Medicine · doi:10.1093/occmed/kqae057 · Cited by 3 · see citing works
“In the case of asthma, although both substances are responsible for causing sensitization, they have been shown to differ in a number of ways in terms of properties and disease mechanisms [31].”
BackgroundAsthma and Cleaning: What’s New?
Ederlé, C., Donnay, C., Khayath, N., Mielcarek, M., & Frederic de, B. L. A. Y. (2018) · Current Treatment Options in Allergy · doi:10.1007/s40521-018-0153-9 · Cited by 3 · see citing works
Metal Fume Fever and Metal-Related Lung Disease
Truncale, T. (2015) · John Wiley & Sons, Inc. eBooks · doi:10.1002/9781118834015.ch40 · Cited by 2 · see citing works
Lemmenes, L. (2013) · Nursing Clinics of North America · doi:10.1016/j.cnur.2012.12.004 · Cited by 2 · see citing works
Stoeva, I., Dencheva, M., Mircheva, K. M., & Chonin, A. (2020) · Folia Medica · doi:10.3897/folmed.62.e48268 · Cited by 2 · see citing works
- Authors
- Malo, J.-L., & Chan-Yeung, M.
- Affiliations
- Hôpital du Sacré-Cœur de Montréal (CA)
- ORCID
- Malo, Jean-Luc
- Venue
- Journal of Allergy and Clinical Immunology
- Publisher
- Elsevier BV
- Published
- 2009-03
- Volume
- 123
- Issue
- 3
- Pages
- 545-550
- ISSN
- 0091-6749 (ISSN-L)
- OpenAlex
- W1965344915
- Cited by
- 145
- References
- 40
- Citations by year
- 2026: 2 · 2025: 2 · 2024: 3 · 2023: 3 · 2022: 10 · 2021: 5 · 2020: 11 · 2019: 6 · 2018: 2 · 2017: 8 · 2016: 6 · 2015: 9 · 2014: 12 · 2013: 18 · 2012: 19
- FWCI
- 9.56
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Allergy and Clinical Immunology (publishedVersion)
- PubMed (publishedVersion)
- The HKU Scholars Hub (University of Hong Kong) (submittedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Occupational exposure and asthma
- Health Sciences › Medicine › Physiology › Asthma and respiratory diseases
- Health Sciences › Health Professions › Occupational Therapy › Occupational Health and Safety in Workplaces
- Keywords
- occupational asthma, asthma triggers, high molecular weight allergens, low molecular weight allergens, immune mechanisms, latency period, work-exacerbated asthma, occupational exposure
- MeSH terms
- Air Pollutants, Occupational, Allergens, Asthma, Humans, Occupational Diseases, Occupational Exposure, Workplace
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
